JULY 11, 2006
  Penn researchers identify small molecules capable of fighting treatment-resistant tumors
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Image    1

Screening many classes of compounds for activity of small molecule candidate drugs in p53 mutant cancer cells. Using light-emitting reporter genes and imaging technology the investigators were able to detect which compounds restored p53-responsivity and killed the mutant cancer cells.

Image Credit: Wafik El-Deiry, MD, PhD, University of Pennsylvania School of Medicine; Proceedings of the National Academy of Sciences


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