| Time course of cell death for neurons which have
been phototransfected with Elk-1 mRNA. In the first panel (O mins.)
the lightning bolts and squares show the region of the dendrite
into which the mRNA was phototransfected. By 180 mins clear indications
of cell death in a cell soma attached to the phototransfected dendrite
is observed (arrow) and by 420 minutes
other cell somas attached to phototransfected dendrites are observed
to be dying. Other cells whose dendrites are not phototrasfected
are observed to be healthy in this image.
Image Credit: Lindy Barrett, PhD and Jai Yoon Sul, PhD, Univeristy
of Pennsylvania School of Medcine; Nature Methods, June 2006
|