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Ed Federico
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May 12, 2004

Landmark Kidney Study at Penn
Seeks Volunteers

Project Aims to Discover how Kidney Disease Affects the Heart

(Philadelphia, PA) – Researchers at the Hospital of the University of Pennsylvania are looking for volunteers to participate in the Chronic Renal Insufficiency Cohort (CRIC) study. The landmark project is being led by Raymond Townsend, MD, Associate Professor of Medicine. The multi-site, national study will try to gain a better understanding of kidney (renal) problems and their effects on the heart.

Volunteers should be 21 to 74 years old with modest impairment of kidney function (this is measured by a blood test called the ‘serum creatinine’ level), but not on dialysis, and must not have undergone a kidney transplant. Researchers will carefully monitor participants’ heart and kidney health for several years through an annual visit, which includes a physical exam, echocardiograms after 1 and 4 years, blood tests, and urine samples. Volunteers and their doctors will be provided with study results. All tests are free of charge and there is modest compensation for participants’ involvement.

Researchers hope to recruit 3000 participants in the USA, with about 450 coming from Pennsylvania, New Jersey and Delaware. Completion of enrollment for the study is expected to take two years, finishing in December 2005, with subjects followed-up for 4 years. The study is sponsored by the National Institutes of Health (NIH), through the branch of the NIH known as the National Institute of Diabetes, Digestive and Kidney Diseases (NIDDK).

Anyone interested should call (215) 662-3636 or (215) 662-2962. The toll free number is 1-866-589-CRIC (2742). More information about the CRIC study can be obtained through the internet by going to www.cristudy.org or by contacting the research team through an email at CRIC@mail.med.upenn.edu.

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PENN Medicine is a $2.5 billion enterprise dedicated to the related missions of medical education, biomedical research, and high-quality patient care. PENN Medicine consists of the University of Pennsylvania School of Medicine (founded in 1765 as the nation’s first medical school) and the University of Pennsylvania Health System (created in 1993 as the nation’s first integrated academic health system).

Penn’s School of Medicine is ranked #2 in the nation for receipt of NIH research funds; and ranked #4 in the nation in U.S. News & World Report’s most recent ranking of top research-oriented medical schools. Supporting 1,400 fulltime faculty and 700 students, the School of Medicine is recognized worldwide for its superior education and training of the next generation of physician-scientists and leaders of academic medicine.

Penn Health System consists of four hospitals (including its flagship Hospital of the University of Pennsylvania, consistently rated one of the nation’s “Honor Roll” hospitals by U.S. News & World Report), a faculty practice plan, a primary-care provider network, three multispecialty satellite facilities, and home health care and hospice.


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