VNS (vagus nerve stimulation) Therapy, the only implantable device specifically indicated for long-term treatment of treatment-resistant depression, is delivered through a small pacemaker-like device that is implanted under the skin in the chest area. A thin, thread-like wire, attached to the generator, runs under the skin to the left vagus nerve and sends mild pulses to the brain.

Image Courtesy: Cyberonics, Inc. ©2005