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Nov 16

Penn Study Finds that Antioxidant Found in Vegetables has Implications for Treating Cystic Fibrosis

Scientists at the University of Pennsylvania School of Medicine discovered that a dietary antioxidant found in such vegetables as broccoli and cauliflower protects cells from damage caused by chemicals generated during the body’s inflammatory response to infection and injury. The finding has implications for such inflammation-based disorders as cystic fibrosis (CF), diabetes, heart disease, and neurodegeneration.
Nov 12
zebrafish development

Penn Study Provides First Clear Idea of How Rare Bone Disease Progresses

While normal human ACVR1 can rescue the altered developmental pattern of a zebrafish embryo lacking the zebrafish ACVR1 gene, the mutated FOP version of ACVR1 over-compensates for the lack of the zebrafish gene and causes excess formation of tail (ventral) structures at the expense of head (dorsal) structures.
An international team of scientists, led by researchers at the University of Pennsylvania School of Medicine, is taking the first step in developing a treatment for a rare genetic disorder called fibrodysplasia ossificans progressiva (FOP), in which the body’s skeletal muscles and soft connective tissue turns to bone, immobilizing patients over a lifetime with a second skeleton. Their latest study provides the first clear glimpse of how FOP might develop at a cellular level in the human body.
Nov 6

Penn Medicine Study Finds Higher Carotid Arterial Stenting Rates Associated with Poorer Clinical Outcomes for Medicare Patients

Among eligible Medicare beneficiaries, increased use of carotid arterial stenting (CAS) procedures to treat carotid stenosis—the narrowing of the carotid artery—is associated with higher rates of mortality and adverse clinical outcomes, including heart attack and stroke, according to researchers from the University of Pennsylvania School of Medicine.
Nov 3

Weight Training Boosts Breast Cancer Survivors’ Body Image and Satisfaction with Intimate Relationships

In addition to building muscle, weightlifting is also a prescription for self-esteem among breast cancer survivors, according to new University of Pennsylvania School of Medicine research. Breast cancer survivors who lift weights regularly feel better about bodies and their appearance and are more satisfied with their intimate relationships compared with survivors who do not lift weights, according to a new study published in the journal Breast Cancer Research and Treatment.

 

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