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August 16, 2004
X Marks the Spot: Vector Insertion
is Viral Specific
Mapping integration sites has implications
for
better-engineered gene therapies and new HIV drugs
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Integration sites in the human genome.
HIV integation sites shown as blue "lollipops";
MLV integration sites shown in lavender; and ASLV integration
sites shown in green in each of the numbered human chromosomes.
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Credit: R.S. Mitchell, B.F. Beitzel, A.R.W. Schroder,
P. Shinn, H.
Chen, C.C. Berry, J.R. Ecker, F.D. Bushman/PLoS Biology |
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