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August 16, 2004

X Marks the Spot: Vector Insertion is Viral Specific

Mapping integration sites has implications for
better-engineered gene therapies and new HIV drugs



Integration sites in the human genome. HIV integation sites shown as blue "lollipops"; MLV integration sites shown in lavender; and ASLV integration sites shown in green in each of the numbered human chromosomes.

Credit: R.S. Mitchell, B.F. Beitzel, A.R.W. Schroder, P. Shinn, H.
Chen, C.C. Berry, J.R. Ecker, F.D. Bushman/PLoS Biology

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