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NOVEMBER 25 , 2008
  Understanding Donor-Recipient Genetics Could Decrease Early Kidney Transplant Complications, Penn Study Suggests
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The three-dimensional structure mapping of the amino acid sequence in the antigen binding domain of the HLA-A molecule. The amino acid sequence was mapped onto its molecular surface. Amino acid variability at position 62 (an important T cell receptor contact site) and 163 (a peptide and a T cell receptor contact site) were found to be associated with increased risk of delayed allograft function.

Credit: Malek Kamoun MD, PhD, University of Pennsylvania
The three-dimensional structure mapping of the amino acid sequence in the antigen binding domain of the HLA-A molecule. The amino acid sequence was mapped onto its molecular surface. Amino acid variability at position 62 (an important T cell receptor contact site) and 163 (a peptide and a T cell receptor contact site) were found to be associated with increased risk of delayed allograft function.
 


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