Department of Obstetrics & Gynecology

Education

Resident Research


Jamie A. Bastek, MD, MSCE
Director of Resident Research



Mary D. Sammel, ScD
Associate Director

Penn is a leading academic medical center with an outstanding basic and clinical research program in women’s health. We believe that residents will benefit from their research experience.  The research program at Penn enhances a resident’s educational experience, provides insight into a career in academic medicine and a one-on-one mentoring relationship with a faculty member, familiarizes residents with research opportunities and skills, and prepares our residents for fellowship training. The residents are also introduced to basic clinical research skills such as study design and statistics in a series of didactic lectures. Residents may apply for research funding by sending requests to the department chair, Dr. Deborah A. Driscoll. The residents present their study findings at the Department’s Annual Resident Research Day each spring.

Our resident research program was established in 2003 under the leadership of  Dr. Michal Elovitz and has been very successful.  The majority of our chief residents and some of our PGY2 and PGY3s have had presentations at national meetings including the Society for Gynecologic Investigation, American Society of Reproductive Medicine, American College of Obstetricians and Gynecologists, and the Society for Maternal Fetal Medicine.

Program

During orientation, the incoming interns will be introduced to the concept of  the research project and its importance.  An overview of the program and a timeline will be described.  Examples of current research projects from each division will be briefly discussed.  During orientation, the incoming interns will take the required IRB course necessary for the involvement in patient research.  For each year during residency, each class will meet with the residency research director in:
  • January.  These meetings will be used to review progress appropriate for each year, to offer guidance and suggestions.  These meetings will be in addition to meetings with each individual mentor.
  • In January/February of intern year, the resident research director will meet with the intern class.  At this meeting, the specifics of the research timetable will be discussed.  A list of potential mentors with their research interests will be distributed. 
  • By September of second year, a mentor must be identified and a research idea submitted including a description of the proposed project (in general terms), methods to be utilized (chart review, etc) is submitted to the director.
  • By May (before Resident Research Day) of second year, a progress report must be submitted.  This form will indicate (1) IRB or IACUC approval, (2) any difficulties noted or perceived in study design, and (3) resource limitations
  • Research will be conducted throughout the residency with a target of preliminary data analysis occurring in the third year. A progress report should be presented in November/December of the third year to the Resident Research Committee. Ideally, research would have sufficient results to allow submission to a national meeting during the third year with attendance in the fourth year. Minimum requirements are presentations in the spring of the fourth year at our annual Resident Research Day.
  • Ideally, the research would have sufficient results to allow submission to a national meeting during the beginning of 4th year.
  • Presentation in spring of 4th year at our annual Resident Research Day.

Research Program Timeline

Research Program Timeline


Excellence in Resident Research Awards

2014 - Nyia Noel, MD, MPH

Risks factors for hospital readmission for patients undergoing benign gynecologic surgery

2013 - Amanda Rohn, MD

Are chorioamnionitis and labor dystocia unintended conseuences of an oxytocin protocol?

2012 - Samantha Weed, MD

Examining the correlation between placental and serum placenta growth factor in preclampsia

2011 - Wendy Benalt, MD

Single Umbilical artery: fetal and neonatal outcomes

2010 - Georgia McCann, MD

Clinical predictors of bevacizumab-induced gastrointestinal perforation

2009 - Jamie Bastek, MD
Adverse Neonatal Outcomes: Examining the Risks Between Preterm, Late Preterm and Term Infants

2008 - Jacob C. Larkin, MD
Disruption of angiogenic signaling in preeclampsia and IUGR: etiologic event or downstream marker of disease?

2007 - Rebecca M. Mazar, MD
Metabolic Score as a Novel Approach to Assessing Preeclampsia Risk

2006 - Heidi S. Harvie, MD, MBA
Cost Analysis of Incorporating a Nurse Practitioner in a Urogynecology Practice

2005 - Irene Su, MD
Taurine and the Taurine Transporter in Unexplained Infertility

2004 - Stacey L. Jeronis, M.D
Persistence of Cervical HPV and CIN 1 in an Inner City Population


Resident Publications and Presentations 2013-2014

Mary Ackenbom, M.D.

Presentation

The Brief Debrief: Improving Communication and Patient Safety Culture on Labor and Delivery. ACOG, April 2014.

Lori Cory, M.D.

Grant

Cervical Cancer Free America

Robert Dood, M.D., MSCE

Publications

Dood RL, Gracia CR, Sammel MD, Haynes K, Senapati S, Strom BL. Endometrial Cancer After Endometrial Ablation vs Medical Management of Abnormal Uterine Bleeding. J Minim Invasive Gynecol. February 2014.

Kaitlyn Edelson, M.D.

Presentations

Edelson PK, Bastek JA, Levine LD. Does antenatal testing for morbid obesity increase the risk of induction of labor? ACOG, May 2014

Rebecca Feldman, M.D.

Publications

Hillman JK, Johnson LN, Limaye M, Feldman RA, Sammel M, Dokras A. Black women with polycystic ovary syndrome (PCOS) have increased risk for metabolic syndrome and cardiovascular disease compared with white women without PCOS. Fertil Steril. February 2014.

Presentations

Hillman JK, Johnson LN, Limaye M, Feldman RA, Sammel M, Dokras A. Black women with polycystic ovary syndrome (PCOS) have increased risk for metabolic syndrome and cardiovascular disease compared with white women without PCOS. ASRM, October 2013

Feldman R, Sckell B, Asgary R. Cervical cancer screening: Knowledge, attitudes, and practices among New York city homeless women. American Public Health Association Annual Meeting, November 2013

Elizabeth Greenstein, M.D.

Presentation

Greenstein EA, Dade AV, Arora VM, Farnan JM. Interruptions During Resident Handoffs on Labor and Delivery: A Mixed-Methods Multi-Site Study. APGO/CREOG National Meeting, February 2014

Adi Hirshberg, M.D.

Publications

Levine LD, Bogner H, Hirshberg A, Elovitz MA, Sammel MD, Srinivas SK: Term induction of labor and subsequent preterm birth. Am J Obstet Gynecol. Oct 2013.

Levine LD, Hirshberg A, Srinivas SK: Term induction of labor and risk of cesarean delivery by parity. J Matern Fetal Neonatal Med. Dec 2013.

Hirshberg A, Levine LD, Srinivas SK: Labor length among overweight and obese women undergoing induction of labor. J Matern Fetal Neonatal Med. Feb 2014.

Hirshberg A, Levine LD, Schwartz N, Durnwald CP: Reversed end-diastolic flow in the middle cerebral artery preceding death in a normally grown fetus. Obstet Gynecol. August 2013.

Hirshberg A, Draper J, Curley C, Sammel MD, Schwartz N.  A random protein-creatinine ratio accurately predicts baseline proteinuria in early pregnancy.  J Matern Fetal Neonatal Med. April 2014

Bastek JA, Hirshberg A, Chandrasekaran S, Owen CM, Heiser LM, Araujo BA, McShea MA, Ryan ME, Elovitz MA. The role of biomarkers and cervical length in predicting preterm birth in asymptomatic, high risk women: The PREDICT study for preterm birth. Obstet Gynecol. August 2013.

Presentations

Levine LD, Hirshberg A, Elovitz MA, Srinivas SK: Does stage of labor at time of cesarean affect risk of subsequent preterm birth? SMFM, February 2014

Hirshberg A, Srinivas SK.  Do clinical factors predict readmission for persistent hypertensive disease in women with preeclampsia?  SMFM, February 2014

Charles Hummel, M.D., Ph.D.

Publications

Diaz, E, Burky, RE III, Hummel, CS, and Farias-Eisner, R. "Early detection of ovarian cancer." Expert review of Obstetrics and Gynecology. March 2013.

White, M, Cohen, J, Hummel, CS, Burky, RB, Cruz, A, and Farias-Eisner, R. "The role of oxidative stress in ovarian cancer: implications for the treatment of patients." In Cancer Oxidative Stress and Dietary Antioxidants. Ed: Victor R. Preedy. Elsevier, 2014.

Carter Monique Owen, M.D.

Publications

Owen CM, Goldstein EH, Clayton JA, Segars JH. Racial and ethnic health disparities

in reproductive medicine: an evidence-based overview. Semin Reprod Med. September 2013.

Connell MT, Owen CM, Segars JH. Genetic Syndromes and Genes Involved in the

Development of the Female Reproductive Tract: A Possible Role for Gene Therapy. J Genet

Syndr Gene Ther 2013.

Stephanie Purisch, M.D.

Presentations

Purisch S, Brandt J, Srinivas S, Bastek J. Is frequency of sexual intercourse during pregnancy

associated with preterm birth? SMFM, February 2014

Brandt J, Purisch S, Srinivas S, Bastek J. Does activity restriction during pregnancy impact preterm birth? SMFM, February 2014

 

Andrea Roe, M.D.

Publications

Roe AH,  Prochaska E, Smith M, Sammel M, Dokras A. Using the Androgen Excess-PCOS Society Criteria to Diagnose Polycystic Ovary Syndrome and the Risk of Metabolic Syndrome in Adolescents. J Pediatr. May 2013.

Anna Sokalska, M.D., Ph.D.

Publications

Villanueva JA, Sokalska A, Cress AB, Ortega I, Bruner-Tran KL, Osteen KG, Duleba AJ. Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. J Clin Endocrinol Metab. March 2013.

Sokalska A, Anderson M, Villanueva J, Ortega I, Bruner-Tran KL, Osteen KG, Duleba AJ. Effects of simvastatin on retinoic acid system in primary human endometrial stromal cells and in a chimeric model of human endometriosis. J Clin Endocrinol Metab. March, 2013.

Villanueva JA, Sokalska A, Cress AB, Ortega I, Bruner-Tran KL, Osteen KG, Duleba AJ. Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. J Clin Endocrinol Metab. March 2013.

Sokalska A, Stanley SD, Villanueva JA, Ortega I, Duleba AJ. Comparison of effects of different statins on growth and steroidogenesis of rat ovarian theca-interstitial cells. Biol Reprod. February 2014.

Ortega I, Villanueva JA, Wong DH, Cress AB, Sokalska A, Stanley SD, Duleba AJ. Resveratrol potentiates effects of simvastatin on inhibition of rat ovarian theca-interstitial cells steroidogenesis. J Ovarian Res. February 2014.

Presentations

Duleba A, Ortega I, Stanley S, Villanueva J, Sokalska A. Effects of lipophilic and hydrophilic statins on growth and steroidogenesis of rat ovarian theca-interstitial cells. SGI, March 2013

Duleba A, Villanueva J, Ortega I, Scott S, Sokalska A. Retinoic acid inhibits proliferation and androgen production of theca-interstitial cells; potentiation of these effects by simvastatin. ENDO: The 95th Annual Meeting & Expo, June 2013 


Resident Research Committee

  • Jamie Bastek, MD, MSCE
  • Deborah A. Driscoll, MD
  • Catherine Salva, MD
  • Mary Sammel, ScD