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Research in Human Behavior and Reproduction Program

Dr. Ellen W. Freeman
Program Director

University of Pennsylvania Health System
Suite 820
3701 Market Street
Philadelphia, PA 19104

Phone: (215)662-3329
Fax: (215)349-5521

Mission Statement

The Human Behavior and Reproduction Program in the Department of  Obstetrics/Gynecology is dedicated to clinical research of behavioral and emotional factors that affect women’s health.  The program was established by the endowment of the Stuart and Emily B.H. Mudd Professorship of Human Behavior and Reproduction with the mandate to combine the knowledge of medicine and women’s health in ways that enhance the quality of life.  Dr. Karl Rickels in the Department of Psychiatry currently holds the Mudd Professorship. The Human Behavior and Reproduction program brings a unique interdisciplinary collaboration to the studies of reproductive issues in the context of behavioral, psychological and social factors. 

About Our Program

The goals of the Human Behavior and Reproduction Program are:

  • Conduct research in the behavioral, physiological and psychosocial aspects of problems in human behavior and reproduction.
  • Improve medical treatments through applications of research findings.
  • Increase the involvement of women in their health care.
  • Supervise and mentor medical, graduate and post-graduate students for research training in the areas of human behavior and reproduction.
  • Current major research areas of the Program are the PMS Program, long-term longitudinal studies of hormones and behaviors linked to ovarian aging, and clinical trials of treatments to improve women’s reproductive health care.

PMS Program

The PMS Program is conducted for the treatment and investigation of premenstrual syndromes (PMS).  For more information about this program, please visit

Ovarian Aging Studies

Supported by the National Institutes of Health, a population-based cohort of late reproductive age women was randomly identified and is now in Year 12 as the cohort participants move through the hormonal transition to menopause.  Studies focus on changes in reproductive hormones and determination of their associations with symptoms commonly attributed to menopause. 

Active Clinical Trials

Clinical trials and research activities are conducted as they relate to the goals of the program. For more detailed information on current studies please visit: