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Hometown
Midland, Texas
College
Texas A&M University, BS Biology
Graduate School
Baylor College of Medicine, PhD Molecular Biology, 1991
Post-Doctoral
University of California, San Francisco
Year Appointed to Penn Faculty
1999
Other Faculty Appointments
Joint Appointment in Radiation Oncology, University of Pennsylvania
Joint appointment School of Dental Medicine, University of Pennsylvania
Adjunct Assistant Professor, University of California, San Francisco
Areas of Expertise
Cancer biology
Molecular biology
Areas of Special Interest
Mechanisms of tumor cell invasion
Lab-on-a-Chip devices for detection of cancer and nodal disease
Current Research Interests
Extracellular matrix regulation of tumor cell invasion and metastasis
DNA and mRNA changes associated with squamous cell carcinoma development and invasion
Positions Held in Major Societies (Past & Present)
Member of Cell and Molecular Biology Graduate Group-Cell Growth and Cancer Program
Link to Ziober CAMB Web Page http://www.med.upenn.edu/camb/faculty/cgc/ziober.html
Selected Publications
Ziober, A. F., Fall, E.M., and Ziober, B.L. The extracellular matrix in oral squamous cell carcinoma: friend or foe? Head and Neck, 28, 740-749, 2006.
Ziober, A. F.; Patel, K. R.; Alawi, F.; Gimotty, P.; Feldman, M. M.; Chalian, A. A.; Weinstein, G. S.; Hunt, J.; Ziober, B. L . Identification of a Gene Signature for Prediction of Oral Squamous Cell Carcinoma. Clinical Cancer Research, 12, 5960-5971, 2006.
Yuen, H.W., Ziober, A.F., Gopla, P., Nasrallah, I. , Fall, E.M., Meneguzzi, G., Ang, H.Q., and Ziober, B.L . Suppression of laminin-5 expression leads to increased motility, tumorigenicity, and invasion. Experimental Cell Research, 309,198-210, 2005.
Nardone, H.C., Ziober, A.F., LiVolsi, V.A., Mandel, S.J., Baloch, Z.W., Weber, R.S. and Ziober B.L. C-met Expression in Tall Cell Variant Papillary Carcinoma of the Thyroid. Cancer, 98, 1386-1393, 2003. Yeh, M.G., Ziober, B.L. and Kramer, R.H. The laminin-binding alpha-7 integrin is regulated by the beta-1D cytoplasmic domain. Mol. Biol. Cell, 14, 3507-3518, 2003.
Ziober, B.L., Silverman, S.S. and Kramer, R.H. Adhesive Mechanisms Regulating Invasion and Metastasis on Oral Cancer. Critical Reviews in Oral Biology12(6):499-510, 2001.
Ziober, B.L., Turner, M.A., Palefsky, J., Banda, M.J., and Kramer, R.H. Type I collagen degradation in invasive oral squamous cell carcinoma. Oral Oncology, 36:365-372, 2000.
Ziober, B.L., Chen, Y.Q., Ramos, D.M., Waleh, N., and Kramer, R.H. Expression of the a7ß1 laminin receptor suppresses melanoma growth and metastatic potential. Cell Growth and Differentiation, 10:479-490, 1999. |
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