Cardiac Function
Simulated 3D tag data set
SPAMM Analysis
Applications
Applications of SPAMM Imaging - Infarct
K9 Cardiomyoplasty analyzed with 2D optical flow
Displacement map of cardiomyoplasty.
Left: Nonstimulated demonstrates uniform displacement over the entire left ventricle
Right: Muscule stimulation resulted in an increase in displacement in the anterior
region of the left ventricle.
Maximum Principal Strain Lambda 1
Left: Uniform strain pattern in the nonstimulated myoplasty
Right: Stimulation increased the principle strain in the aterior region indicating an improvement in
function.
3D Surface Modeling
3 Month Post-MI, Control (left) and Treated (right)
Left: Created Anterior Infarct Right: Placed titanium Markers at BZ
Short axis image of an ovine infarct model eight weeks post infarct
with marker indicating border zone region. The border zone was
considered to be the adjacent myocardium within a 20 degree arc of
the marker.
In the non-infarct borderzone strain increased linearly from end-diastole to end-systole. Strain increased during isovolumic contraction in the control group but decreased thereafter. In the CSD strain increased then remained constant and dramatically increased during late ejection.
The University of Pennsylvania Health System, Philadelphia, PA © 2006, The Trustees of the University of Pennsylvania
