ATTENTION: Change in SAIF application process.
Please see "Application Forms & Instructions" page for details
Mission Statement

The Small Animal Imaging Facility (SAIF) of the University of Pennsylvania provides multi-modality radiological imaging and image analysis for cells, tissues, and small animals. The SAIF combines state-of-the-art instrumentation and a nationally recognized staff to assist investigators with a wide range of imaging based experimental approaches. The SAIF currently provides a comprehensive suite of imaging modalities including: magnetic resonance imaging (MRI) and spectroscopy (MRS), optical imaging (including bioluminescence, fluorescence, and near-infrared imaging), computed tomography (CT), positron emission tomography (PET), single photon emission computed tomography (SPECT), and ultrasound (US).
In addition, dedicated housing is available for mice and rats undergoing longitudinal imaging studies. Ancillary facilities and resources of the SAIF are devoted to chemistry, radiochemistry, image analysis and animal tumor models, including assistance with animal handling.
Drs. Mitchell Schnall, Lewis Chodosh and Jerry Glickson serve as Faculty Co-Directors for the SAIF, and Dr. Stephen Pickup serves as Technical Director.
The SAIF is organized into four Imaging Sub-Cores, each of which is overseen by a faculty director, as well as an animal holding unit.
These include:
- MRI/MRS (MRI, MRS): Dr Stephen Pickup
- Nuclear Medicine (PET, SPECT, CT): Dr Joel S Karp
- Optical/Bioluminescence (Bioluminescence, Fluorescence, near-IR): Dr Wafik El-Deiry
- Ultrasound (Gray-scale, 3D, color and power Doppler): Dr Sandy Sehgal
- Animal Housing (Mouse (5 Richards) and Rat (2 Richards)): Dr Richard Freifelder
What Services are Available?
Detailed descriptions of the individual Sub-Cores, their resources, and pricing structure are provided within the following pages:
In addition, space renovations are currently underway to consolidate the MR, Optical, and Ultrasound components of the SAIF into a single location in 1 John Morgan along with convenient access to additional on-site animal housing. The consolidated facility will include a new 9.4T horizontal bore MR spectrometer and is expected to provide the research community with a unique opportunity to apply multiple imaging modalities to biological questions within an integrated imaging suite.
Who Do I Contact?
Technical/Scientific Questions: Specific Sub Core Director
Animal Housing
Application Process
Billing
