UPHS Radiology Department Official Web Site -- LSNI

Research of the Laboratory is aimed at quantitatively characterizing tissue microarchitecture and its relationship to physiology and function by means of spatially resolved nuclear magnetic resonance in animals and humans. The current focus of the Laboratory is on the development of new methods for the quantitative assessment of metabolic bone disease by means of the MR-based "virtual bone biopsy", and new methods for the study of tissue mineralization. A second line of research focuses on the quantification of carotid artery disease and its implications on brain perfusion. Additional projects deal with ultrahigh-resolution microscopy of neuronal architecture in spinal cord injury models as well as methods for indirect assessment of tissue microstructure by means of diffusion diffraction, anisotropic dipolar relaxation and multiple quantum coherence imaging.

Felix W. Wehrli, Ph.D., Director
Professor of Radiologic Science, Biochemistry and Biophysics,
1 Founders
University of Pennsylvania Medical Center
3400 Spruce Street Philadelphia
PA 19104, USA