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Ultrasound
Research Laboratory

Department of Radiology
University of Pennsylvania

Chandra M Sehgal PhD
Director
Professor
Department of Radiology
1 Silverstein
3400 Spruce Street
University Of Pennsylvania
Philadelphia, PA 19104

Phone: 215-349-5461 (Office)
215-662-6673 (Lab)
Fax: 215-615-4666
Email: sehgalc@uphs.upenn.edu

Ultrasound Research Laboratory
Department of Radiology | University of Pennsylvania

Publications and Presentations


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1981 1985 1989 1993 1997 2001 2005


2008
Andrew K.W. Wood, DVSc, PhD, Ralph M. Bunte, DVM, Heather E. Price, BS, Margaret S. Deitz, BS, Jeff H. Tsai, BS William M.-F. Lee, MD, Chandra M. Sehgal, PhD The Disruption of Murine Tumor Neovasculature by Low-intensity Ultrasound—Comparison Between 1- and 3-MHz Sonication Frequencies Acad Radiol 2008; 15:1133–1141
2007
Gabriela S Seiler, Lisa S Ziemera, Susan Schultzc, William M.F Lee and Chandra M Sehgal Dose-response relationship of ultrasound contrast agent in an in vivo murine melanoma model Cancer Imaging (2007) 7, 216-223
G. C. Karakousis, C. Menon, S. Schultz, D. G. Buerk, C. Sehgal, D. L. Fraker;Perfusate Acidification Enhances Response to Melphalan Isolated Limb Perfusion by a Nitric Oxide Mediated Tumor Specific Reduction in Blood Flow. Association for Academic Surgery and Society of University Surgeons—ABSTRACT #399
Robert E. Krisch, MD, PhD, Chandra M. Sehgal, PhD, Peter H. Arger, MDPredicting PSA Response of Prostate Cancer to Radiation Therapy with Doppler Sonography JOURNAL OF CLINICAL ULTRASOUND—DOI 10.1002/jcu 2007 Wiley Periodicals, Inc.
Farooq A. Chaudhry, MD, Sripal Bangalore, MD, MHA, Shrikanth Upadya, MD, Ajay Shah, MD, Hossein Eftekhari, MD, Danny Pudpud, RDCS, and Chandra M. Sehgal, PhD,Cross-sectional Imaging Identifies Flow-mediated Vasodilatation More Accurately Compared with Longitudinal Imaging Journal of the American Society of Echocardiography Volume 20 Number 12, 2007
Wood A.K.W., Bunte R.M., Cohen J.D., Tsai J.H., Lee W.M-F., Sehgal C.M.The antivascular action of physiotherapy ultrasound on a murine tumor: role of a microbubble contrast agent. Ultrasound in Med. & Biol., 2007;33 (12):1901-1910.
A.K.W. Wood, R.M. Bunte, S. Ansaloni, W.M-F. Lee, C.M. Sehgal.Histopathologic studies of the disruption of murine tumor vasculature by mild-intensity ultrasound (abstract). Proceedings 14th Meeting, International Veterinary Radiology Association, Vancouver, Canada. Veterinary Radiology and Ultrasound 2007; 48:188.
2006
Chandra M. Sehgal & Susan P. Weinstein & Peter H. Arger & Emily F. Conant A Review of Breast Ultrasound J Mammary Gland Biol Neoplasia (2006) 11: 113–123
Susan P. Weinstein, MD, Emily F. Conant, MD, and Chandra Sehgal, PhDTechnical Advances in Breast Ultrasound Imaging Seminars in Ultrasound, CT and MRI 27:273-283
Bunte R.M., Ansaloni S., Sehgal C.M., Lee W.M-F., Wood A.K.W. Histpathological observations of the antivascular effects of physiotherapy ultrasound on a murine neoplasm. Ultrasound in Med.& Biol., 2006, 32 (3):453-461.
Wood A.K.W., Bunte R.M., Ansaloni S., Lee W.M-F., Sehgal.C.M. The antivascular actions of mild intensity ultrasound on a murine neoplasm. Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound. Edited by G.T. Clement, N.J. McDannald, and K.Hynynen, American Institute of Physics, 2006:467-471.

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2005
TW Cary, EF Conant, PH Arger, and CM Sehgal, Diffuse boundary extraction of breast masses on ultrasound by leak plugging. Med. Phys. 32, 3318-3328 (2005)
Weinstein SP, Conant EF, Sehgal CM, Woo IP, Patton JA. Hormonal variations in the tissue vascularity of the breast tissue. J Ultrasound Med 2005, 24:67-72.
Andrew K.W. Wood, Sara Ansaloni, Lisa S. Ziemer, William M.F. Lee, Michael D. Feldman, and Chandra M. Sehgal The Antivascular Action of Physiotherapy Ultrasound on Murine Tumors Ultrasound in Med. & Biol., Vol. 31, No. 10, pp. 1403–1410, 2005
Ansaloni S., Arger P.H., Cary T.W., Sehgal C.M. Evaluation of Contrast-enhanced Power Doppler Imaging for Measuring Blood Flow. Medical Imaging 2005, Ultrasonic Imaging and Signal Processing, vol 5750.
Arger P.H., Schultz S.M., Sehgal C.M., Cary T.W., Aronchick J. Teaching Medical Students Diagnostic Sonography. J Ultrasound Med 2005; 24:1365-1369.
Song J.H., Venkatesh S.S., Conant E.F., Arger P.H., Sehgal C.M. Comparative Analysis of Logistic Regression and Artificial Neural Network for Computer-Aided Diagnosis of Breast Masses. Academic Radiology 2005; 12:487-495.
Song J.H., Venkatesh S.S., Conant E.F., Cary T.W., Arger P.H., Sehgal C.M. Artificial Neural Network to Aid Differentiation of Malignant and Benign Breast Masses by Ultrasound Imaging. Medical Imaging 2005, Ultrasonic Imaging and Signal Processing, vol 5750.
Chaudhry M., Rosen M., Schultz S., Englander S., Sehgal S., Tomaszewski M., Schnall M. Multimodality Assessment of Breast Tumor Physiology and Metabolism. SPIE vol 5746, p 23-30 2005.
Ziemer L.S., Schultz S.M., Lee W.M.F., Sehgal C.M. Dose Effect Relationship of an Ultrasound Contrast (Optison) Pre and Post Antivascular Treatment. RSNA Scientific Assembly and Annual Meeting 2005.
Tsai J.H., Makonnen S., Feldman M., Sehgal C.M., Maity A., Lee W.M.F. Ionizing Radiation Inhibits Tumor Neovascularization by Inducing Ineffective Angiogenesis. Cancer Biology & Therapy 4:12, 2005.
Sehgal C.M., Kao Y.H., Cary T.W., Arger P.H., Mohler E.R. User-guided Automated Segmentation of Time-series Ultrasound Images for Measuring Vasoreactivity of the Brachial Artery Induced by Flow Mediation. Medical Imaging 2005, Ultrasonic Imaging and Signal Processing, vol 5750.
Yu G., Durduran T., Zhou C., Wang H., Putt M.E., Saunders H.M., Sehgal C.M., Glatstein E., Yodh A.G., Busch T.M. Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy. Clinical Cancer Research 2005; 11 (9).
Zimer L.S., Lee W.M.F., Vinogradov S.A., Sehgal C.M., Wilson D.F., Oxygen Distribution in Murine Tumors: Characterization Using Oxygen-dependent Quenching of Phosphorescence. Journal of Applied Physiology 98:1503-1510, 2005.
Puthumana J.J., Sehgal C.M., Upadaya S., Syed T.M., Kim I., Bangalore S., Kao Y.H., Chaudhry F.A. Cross Sectional Imaging More Accurately Identifies Flow Mediation Vasodilatation. Circulation 2004; 110 (17) III-486: 2057.
Wood A.K., Bunte R.M., Ansaloni S., Lee W.M.F., Sehgal C.M. The Antivascular Actions of Mild Intensity Ultrasound on a Murine Neoplasm. 5th International Symposium on Therapeutic Ultrasound, October 2005.

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2004
Arger PH, Malkowicz SB, VanArsdalen KN, Sehgal, CM, Holzer A, Schultz SM. Color and power Doppler sonography in the diagnosis of prostate cancer comparison between vascular density and total vascularity. J Ultrasound Med. 2004 May;23(5): 623–30.
Weinstein SP, Conant EF, Mies C, Acs G, Lee S, Sehgal CM. Posterior acoustic shadowing in benign breast lesions - sonographic-pathologic correlation. J Ultrasound Med. 2004 Jan; 23(1):73-83.
Sehgal CM, Cary TW, Kangas SA, Weinstein SP, Schultz SM, Arger PH, Conant EF. Computer-based margin analysis of breast ultrasound for differentiating malignant and benign masses. J Ultrasound in Medicine, 2004, 23: 1201-1209.
Sehgal CM. Tumor perfusion by multigated contrast-enhanced Doppler imaging. P431-433. 10th Annual Symposium on Ultrasound Contrast Agents May 11, 2004. The Leading Edge in Diagnostic Ultrasound
Sehgal CM, Kangas SA, Cary TW, Weinstein SP, Schultz SM, Arger PH, Conant EF. Quantitative description of solid breast nodules by ultrasound imaging Proc SPIE Vol 5373, p. 324-330, Medical Imaging 2004: Ultrasonic Imaging and Signal Processing; William F. Walker, Stanislav Y. Emelianov; Eds.
Sehgal CM, Cary TW, Kangas SA, Weinstein SP, Schultz SM, Arger PH, Conant EF. Computer-based margin analysis of breast ultrasound for differentiating malignant and benign masses. J Ultrasound in Medicine, 2004, 23: 1201-1209.
Sehgal CM, Kangas SA, Cary TW, Weinstein SP, Schultz SM, Arger PH, Conant EF. Quantitative description of solid breast nodules by ultrasound imaging Proc SPIE Vol 5373, p. 324-330, Medical Imaging 2004: Ultrasonic Imaging and Signal Processing; William F. Walker, Stanislav Y. Emelianov; Eds.
Cary T.W., Conant E.F., Arger P.H., Sehgal C.M. Semi-automated Boundary Detection of Breast Masses in Ultrasound Images. RSNA Scientific Assembly and Annual Meeting 2004.
Schultz S.M., Conant E.F., Weinstein S.P., Kangas S.A., Arger P.H., Schnall M.D. Evaluation of Ultrasound Imaging Parameters on the Fremitus Effects in Breast Imaging. RSNA Scientific Assembly and Annual Meeting 2004.
Sehgal C.M., Cary T.W., Arger P.H., Lee W.M. Tumor Perfusion by contrast-enhanced Doppler Imaging. J Ultrasound Med 23: S1-S153, June 2004.
Sehgal C.M., Cary T.W., Kangas S.A., Weinstein S.P., Schultz S.M., Arger P.H, Schnall M.D., Conant E.F. Discrimination of Ultrasound Breast Masses Using Computer-based Margin Analysis. J Ultrasound Med 23: S1-S153, June 2004.
Cary T.W, Arger P.H., Sehgal C.M. Dynamic region growing for breast tumor boundary detection. J Ultrasound in Med. 2004 Jun; 23(S6):S109.
Phatak N., Ahmad , Ginsberg G., Sehgal C., Kochman M. Computer-assisted Analysis of EUS Images for Parenchymal and Border Differences in Pancreatic Mass Lesions. Gastrointestinal Endo. 59 (5): AB221-AB221 Suppl. S APR 2004.
Kangas S.A., Schultz S.M., Conant E.F., Weinstein S.P., Arger P.H., Schnall M.D., Sehgal C.M. Differences Between Conventional and Compound Ultrasound Images in Solid Breast Lesions. RSNA Scientific Assembly and Annual Meeting 2004.

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2003
Kamotani Y, Lee WM, Arger PH, Cary TW, Sehgal CM. Multigated contrast-enhanced power Doppler to measure blood flow in mice tumors. Ultrasound Med Biol. 2003 Jul; 29(7):977-84.
Kao YH, Mohler ER, Arger PH, Sehgal CM. Brachial artery: measurement of flow-mediated dilatation with cross-sectional US-technical validation. Radiology. 2003 Sep;228(3):895-900.
Knox VW 4th, Sehgal CM, Wood AK. Correlation of ultrasonographic observations with anatomic features and radiography of the elbow joint in dogs. Am J Vet Res. 2003 Jun; 64(6):721-6.
Menon C, Polin GM, Prabakaran I, Hsi A, Cheung C, Culver JP, Pingpank JF, Sehgal CS, Yodh AG, Buerk DG, Fraker DL. An integrated approach to measuring tumor oxygen status using human melanoma xenografts as a model. Cancer Res. 2003 Nov 1; 63(21):7232-40.
Sehgal CM, Arger PH, Holzer AC, Krisch RE. Correlation between Doppler vascular density and PSA response to radiation therapy in patients with localized prostate carcinoma. Acad Radiol. 2003 Apr; 10(4):366-72.
Guoqiang Yu, Turgut Durduran, Theresa M. Busch, Hsing-Wen Wang, Chao Zhou, H. Mark Saunders, Chandra M. Sehgal, Arjun G. Yodh. Noninvasive monitoring hemodynamic responses in RIF tumors during and after PDT. Proc SPIE Vol 4952. p. 131-139, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy XII; David Kessel; Ed.

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2002
Arger PH, Malkowicz SB, Van Arsdalen KN, Sehgal CM, Holzer A, Barrett R. Impact of added biopsy areas on prostate cancer detection: preliminary analysis. J Ultrasound Med. 2002 Feb; 21(2):135-9.
Lee JC, Kim DC, Gee MS, Saunders HM, Sehgal CM, Feldman MD, Ross SR, Lee WM. Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res. 2002 Feb 1; 62(3):747-55.
Loren DE, Sehgal CM, Ginsberg GG, Kochman ML. Computer-assisted analysis of lymph nodes detected by EUS in patents with esophageal carcinoma. Gastrointestinal Endoscopy.2002;6(5):742-46.
Mohler ER 3rd, Sehgal CM, Ferrari VA, Parmacek M, Shih A, Wilensky RL. A novel ultrasound method for evaluation of collateral development in limb ischemia. Vasc Med. 2002 Aug;7(3):169-75.
Weinstein SP, Sehgal CM, Conant EF, Patton JA. Microcalicification in breast tissue phantoms visualized with acoustic resonance coupled with power Doppler US: Initial observations. Radiology.2002;224:265-69.

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2001
Arger PH, Sehgal CM, Conant EF, Zuckerman J, Rowling SE, Patton JA, Study P. Interreader variability and predictive value of US descriptions of solid breast masses: pilot study. Acad Radiol. 2001 Apr; 8(4):335-42.
Gee MS, Saunders HM, Lee JC, Sanzo JF, Jenkins WT, Evans SM, Trinchieri G, Sehgal CM, Feldman MD, Lee WM. Doppler ultrasound imaging detects changes in tumor perfusion during antivascular therapy associated with vascular anatomic alterations. Cancer Res. 2001 Apr 1; 61(7):2974-82.
Sehgal CM, Arger PH, Silver AC, Patton JA, Saunders HM, Bhattacharyya A, Bell CP. Renal blood flow changes induced with endothelin-1 and fenoldopam mesylate at quantitative Doppler US: initial results in a canine study. Radiology. 2001 May; 219(2):419-26.
Micklethwaite L, Wood AK, Sehgal CM, Polansky M, Dowling BA, Dart AJ, RoseRJ, Hodgson DR. Use of quantitative analysis of sonographic brightness for detection of early healing of tendon injury in horses. Am J Vet Res. 2001 Aug; 62(8):1320-7.

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2000
Mohler ER 3rd, Klugherz B, Goldman R, Kimmel SE, Wade M, Sehgal CM. Trial of a novel prostacyclin analog, UT-15, in patients with severe intermittent claudication.Vasc Med. 2000; 5(4):231-7.
Sehgal CM, Arger PH, Rowling SE, Conant EF, Reynolds C, Patton JA. Quantitative vascularity of breast masses by Doppler imaging: regional variations and diagnostic implications. J Ultrasound Med. 2000 Jul; 19(7):427-40.

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1999
Arger PH, Sehgal CM, Pugh CR, Kotlar EY, Kirchofer JI, KC Bovee. Evaluation of change in blood flow by contrast-enhanced power Doppler imaging during norepinepherine-induced renal vasoconstriction. J Ultrasound Med.1999;18:843-51.

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1998
Sehgal CM, Arger PH, Pugh CR, Kirchofer JI, Kotlar EY, Bovee KC. Comparison of power Doppler and B-scan sonography for renal imaging using a sonographic contrast agent. J Ultrasound Med. 1998 Dec; 17(12):751-6.

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1997
Evans SM, Laughlin KM, Pugh CR, Sehgal CM, Saunders HM. Use of power Doppler ultrasound-guided biopsies to locate regions of tumor hypoxia. Br J Cancer. 1997; 76(10):1308-14.
Sehgal CM, Arger PH. Mathematical modeling of the dilution curves for ultrasonographic contrast agents. J Ultrasound Med. 1997 Jul; 16(7):471-9.
Sehgal CM, Arger PH, Bovee KC, Pugh CR, Kirchofer JI. Comparative. analysis of renal flow using contrast power Doppler and gray scale ultrasound. Proc SPIE. 1997.3033:209-214. Medical Imaging. Physiology and Function from Multidimensional Images; Eric A. Hoffman ; Ed.

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1996
Pugh CR, Arger PH, Sehgal CM. Enhancement of Power, Color and spectral Doppler by ultrasonic contrast agent. J Ultrasound Med. 1996 Dec;15(12):843-52.
Shlanskey-Goldberg RD, Cines DB, Sehgal CM. Catheter-delivered ultrasound potentiates in vitro thrombolysis. J Vasc Interv Radiol. 1996 May-Jun; 7(3):313-20.

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1995
Sehgal CM. Nonlinear ultrasonics to determine molecular properties of pure liquids. Ultrasonics. 1995;33(2): 155-61.
Sehgal CM, Arger PH, Pugh CR. Sonographic enhancement of renal cortex by contrast media. J Ultrasound Med. 1995 Oct;14(10):741-8.
Sehgal CM, Arger PH, Pugh CR. Influence of post-processing curves on contrast-echographic imaging. J Ultrasound Med. 1995 Oct;14(10):735-40.
Wang SL, Sutton MS, Sehgal CM. Quantitation of organ symmetry by diagnostic ultrasonic imaging: A group theoretical Approach. Med Phys. 1995 Oct;22(10):1611-8.

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1994
Chandrasekaran K, Sehgal CM, Hsu TL, Young N., D’Adamo AJ, Robb RA, Pandian NG. Three dimensional volumetric ultrasound imaging of arterial pathology from two dimensional intravascular ultrasound. An in vitro study. Angiology. 1994 Apr;45(4):253-64.
Sehgal CM, Broderick GA, Whittington R, Gorniac RJ, Arger PH. Three-dimensional ultrasound and volumetric assessment of the prostate. Radiology. 1994 Jul;192(1):274-8.
Wood AK, Sehgal CM, Reef VB. Three-dimensional sonographic imaging of equine superficial digital flexor tendon. Am J Vet Res. 1994 Nov;55(11):1505-8.

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1993
Laskey WE, Brady ST, Kussmaul WG, Waxler AR, Krol J, Hermann HL, Hirshfeld Jr. JN, Sehgal C. Intravascular ultrasonographic assessment of the results of coronary artery stenting. Am Heart J. 1993 Jun;125(6):1576-83.
Sehgal CM, Leveen, RF, Shlansky-Goldberg RD. Ultrasound assisted thrombolysis: Preliminary studies. Investigative Radiology.1993 Oct; 28(10):939-43.
Sehgal CM. Quantitative relationship between tissue composition and scattering of ultrasound. J Acoust Soc Am. 1993 Oct;94(4):1944-52.
Wood AK, Sehgal CM, Polansky M. The sonographic brightness of flexor tendons and ligaments of metacarpal region of the horse. Am J Vet Res. 1993 Dec;54(12):1969-74.

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1992
Chandrasekeran K, D'Adamo AJ, Sehgal CM. Three-dimensional reconstruction of ultrasonic images in intravascular ultrasound imaging. In Intravascular Ultrasound Imaging.Ed Johnas JM York PG Churchill, Livingston, NY, 141-147, 1992.
Sehgal, CM, Guidera SA, Yeramusu VG, Laskey WE. Measurements of regional mechanical stress on blood vessels by intravascular ultrasound imaging. Ultrasonics Symposium, 1992. Proceedings., IEEE 1992 , 20-23 Oct. 1992 Pages:1061 - 1069 vol.2.
Wood AK, Polansky M, Kundel HL, Reef V, Sehgal CM. Equine tendon and ligament sonography: Current concepts and future directions. Proc 38th Annual American Association of Equine Practitioners, 253-264, ISSN 0065-7182, Lexington, Ky, 40511, 1992.

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1991
Sehgal CM, Lewallen DG, Robb RA, Greenleaf JF. Ultrasonic imaging of musculoskeletal system. News in Physiological Sciences.1991; 6:16-20.
Sehgal CM, Chandrasekeran K, Pardian N. Volumetric-intravascular imaging by high frequency ultrasound. Diagnostic and Therapeutic Cardiovascular Interventions, Progress in Biomedical Optics.SPIE 226-233, Vol 1425, 1991.
Kim D., Nicholson J.A., Greenleaf J.F., Sehgal C.M. Least squares and imaging using phase and frequency measurements of the nonlinear parameter B/A. Acoustical Imaging, Vol. 18, Edited by H. Lee and G. Wade. Plenum Press, New York, 1991. Page 305-316.
Lu J., Kinnick R., Greenleaf J.F., Sehgal C.M. Multi-electrical excitation of a transducer for ultrasonic imaging. Acoustical Imaging, Vol. 18, Edited by H. Lee and G. Wade. Plenum Press, New York, 1991. Page 511-519.
Sehgal C.M., Greenleaf J.F. Ultrasonic computed tomography for imaging bones and adjoining soft tissues. Material Research Society Symposium Proceedings. Vol. 217. Advanced Tomographic Imaging Methods for the Analysis of Materials. November 28-30, 1990, Boston, MA. Page 157-165.

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1990
Chu A, Sehgal CM, Greenleaf JF. Use of gray value distribution of run lengths for texture analysis. Pattern Recognition Letters. 1990;11, 415-20.
Kim D, Greenleaf JF, Sehgal CM. Ultrasonic imaging of the nonlinear parameter B/A: simulation studies to evaluate phase and frequency modulation methods. Ultrasound in medicine and Biology. 1990;16, 175-81.
Sehgal CM, Errabolu RL, Greenleaf JF. Interrelationship between acoustic nonlinearity and sound speed in biological tissues. In Frontiers of Nonlinear Accoustics: Proceedings of 12th INSA. Eds Hamilton MF and Blackstock DT. Elsevier Applied Science
Kim D, Nicholson JA, Sehgal CM, Greenleaf JF. Least square estimation and imaging using phase and frequency measurements of nonlinear parameter. In Hua Lee and Glen Wade, editors, Acoustical Imaging, Proceedings of the 18th International Symposium on Acoustical Imaging, Santa Barbara, California, volume 18, pages , New York, September 1990. Plenum Press.
Lu JY, Kinnick R, Greenleaf JF, Sehgal CM. Multi-electrical excitation of a transducer for ultrasonic imaging. In Hua Lee and Glen Wade, editors, Acoustical Imaging, Proceedings of the 18th International Symposium on Acoustical Imaging, Santa Barbara, California, volume18, New York, September 1990. Plenum Press.

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1989
Kim, D, Kinnick RR Sehgal CM, Greenleaf JF. Doppler ultrasound parametric spectral estimation using third-order statistics. Engineering in Medicine and Biology Society, 1989 Proceedings IEEE,9-12 Nov. 1989 vol 2. P:685-86.

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1988
Errabolu RL, Sehgal CM, Bahn RC, Greenleaf JF. Measurement of ultrasonic nonlinear parameter in excised fat tissues. Ultrasound in Med and Biol. 1988;14(2):137-46.
Sehgal CM, Lewallen DG, Nicholson JA, Robb RA, Greenleaf JF. Ultrasound Transmission and reflection computerized tomography for imaging bones and adjoining soft tissue. Ultrasonics Symposium, 1988. Proceedings., IEEE 1988 , 2-5 Oct. 1988 Pages:849 - 852 vol.2
Verrall RE, Sehgal CM. Sonoluminescence. In Suslick KS editor.Ultrasound Its Chemical Physical and Biological Effects. 1988 p227-86.NY NY. VCH Publishers.

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1987
Errabolu RL, Sehgal CM, Greenleaf JF. Dependence of ultrasonic nonlinear parameter B/A on fat. Ultrasonic Imaging.1987 July; 9(3):180-94.
Verrall RE, Sehgal CM. Sonoluminescence. Ultrasonics. 1987; 25:29-30.
Greenleaf JF, Ylitalo J, Sehgal CM. New ultrasonic tomographies. Invited talk, The 6th Congress of the European Federation of Societies, EUROSON 87, June 8-10, 1987,Helsinki - Finland

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1986
Sehgal CM, Porter B, Greenleaf JF. Ultrasonic nonlinear parameters and sound speed of alcohol-water mixtures. J Acoust Soc Am. 1986 ;79(2) :566-70.
Sehgal CM, Brown M, Bahn RC, Greenleaf JF. Measurement and use of acoustic nonlinearity and sound speed to estimate the composition of excised livers. Ultrasound in Med and Biol. 1986 ;12(11) :865-74.
Sehgal CM, Greenleaf JF. Correlative study of properties of water in biological systems using ultrasound and magnetic resonance. Magn Reson Med. 1986;3 :976-85.
Sehgal CM, Ravi-Meher EL, Greenleaf JF. Measurement of acoustic nonlinearity and sound speed to estimate composition of excised livers. Proceedings of the Institute of Acoustics.1986;8 (Part 2):63-9.

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1985
Sehgal CM, Porter B, Greenleaf JF. Relationship between acoustic nonlinearity and the bound and unbound states of water. IEEE 1985 Ultrasonics Symposium, 85CH2209-5, II pp.883-886, 1985.

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1984
Sehgal C, Greenleaf JF. Diffraction of ultrasound by soft tissues: The inhomogeneous continuous model. In Acoustical Imaging. New York, Plenum Publishing Corporation, 13:217-231, 1984.
Sehgal CM, Greenleaf JF. Scattering of ultrasound by tissues. Ultrasonic Imaging. 1984 Jan; 6(1) :60-80.
Sehgal CM, Bahn RC, Greenleaf JF. Measurement of acoustic nonlinearity parameter B/A of human tissues by thermodynamic method. J Acoust Soc Am. 1984;76 :1023-29.

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1983
Sehgal CM, Wang SY. Chemical dosimetry for the measurement of transient cavitation activity. IEEE Transactions on Sonics and Ultrasonics. 1983;30 (6): 374-9.

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1982
Sehgal C, Yu TJ, Sutherland RG, Verrall RE. Use of 2,2 diphenyl-1-picrylhydryzl to investigate the chemical behavior of free radicals induced by ultrasonic cavitation. J Phys Chem. 1982; 86:2982-2986.
Sehgal C, Verrall RE. A review of the electrical hypothesis of sonoluminescence. Ultrasonics. 1982; 37.
Sehgal CM, Greenleaf JF. Ultrasonic absorption and dispersion of biological media: a postulated model. J Acoust Soc of Am. 1982; 72:1711-1718.

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1981
Sehgal C, Sutherland RG, Verrall RE. Sonoluminescence from Br2 and I2 saturated solutions. J Phys Chem. 1981; 85:315-317.
Sehgal C, Wang SY. Threshold intensities and kinetics of sonoreaction of thymine in aqueous solutions at low ultrasonic intensities. J Am Chem Society. 1981; 103:6606-6611.

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1980
Sehgal C, Sutherland RG, Verrall RE. Optical Spectra of sonoluminescence from transient and stable cavitation in water saturated with various gases. J Phys Chem. 1980; 84:388-395.
Sehgal C, Sutherland RG, Verrall RE. Sonoluminescence of NO and NO2 saturated water as a probe of acoustic cavitation. J Phys Chem. 1980; 84:396-401.
Sehgal C, Sutherland RG, Verrall RE. Sonoluminescence intensity as a function of bulk solution temperatures. J Phys Chem. 1980; 84:525-528.
Sehgal C, Sutherland RG, Verrall RE. Selective quenching of species that produce sonoluminescence. J Phys Chem. 1980; 84:520-531.
Sehgal C, Sutherland RG, Verrall RE. Sonoluminescence of argon saturated copper sulfate solution. J Phys Chem. 1980; 84:227.
Sehgal C, Sutherland RG, Verrall RE. Cavitation induced oxidation of Fe2+ in the presence of alcohols. J Phys Chem. 1980; 84:2920-2922.

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1979
Sehgal C, Steer RP, Sutherland RG, Verrall RE. Sonoluminescence of argon alkali salt solutions as a probe of acoustic cavitation. J Chem Phys. 1979; 70: 2242.

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1977
Sehgal C, Steer RP, Sutherland RG, Verrall RE. Sonoluminescence of aqueous solutions J Phys Chem. 1977; 81:2618-2620.

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Phone: 215-349-5461 (Office)
215-662-6673 (Lab)
Fax: 215-615-4666
Email: sehgalc@uphs.upenn.edu

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