CACTIS - Procedures & Policies

Listed are the guidelines that must be followed by all groups who will have access to the CT Scanners for research purposes. It is the policy of CACTIS to maintain a safe environment and to promote a conscientious approach to research projects and developments.

Overview | Definitions | Health & Safety | Qualifications | CT Guidelines


  • Animal Contact: Any contact with mammals, reptiles, amphibians, birds or fish. Animal contact may be direct or indirect. Indirect contact refers to contact with animal products or with items that have been in contact with the animals or their products. Animal products include unpreserved tissues, blood, excreta, body fluids or discharges, hair, dander, etc… Items that could be contaminated by animal products may include sharps, cages, clothing, gloves, etc.
  • Hazard: Anything that has been scientifically proven to have an adverse health effect in a person. Hazards can be of chemical (e.g. disinfectants, preservatives), physical (e.g. bites, kicks and scratches, needle sticks, heavy lifting) or biological (zoonotic agents,) origin.
  • Zoonotic Diseases: A group of infectious diseases transmittable between animals and humans. In some cases, the infected animal may show no signs of illness while still being capable of transmitting an infectious agent.
  • Fomite: An object that, while not capable of being infected, is able to harbor pathogenic microorganisms, which may be transmitted to others.
  • Pathogen: An organism that causes disease in another organism
  • ULAR - University Laboratory Animal Resources: Responsible for the procurement, care, and use of all University-owned animals used for teaching, research, and testing as approved by the Institutional Animal Care and Use Committee (IACUC) and as mandated by federal law and regulations.
  • ID (HUP): Infectious Diseases Department at the Hospital of the University of Pennsylvania
  • OH - Occupational Health: Handles health and exposure issues of employees of the hospital and university.
  • SHC - Student Health Center: This department handles the health issues of students at University of Pennsylvania.
  • Researcher: Any individual participating in the scanning of animals in the CT section. This includes investigators, anesthesia techs, and CT technologists.
  • Standards of Classifications of bio-hazards as defined by the National Institute of Health (NIH):
    • RG - Risk Groups partition animal research studies by the possible etiologic exposures which could take place.
    • Agent - A substance that causes a change: a chemical agent; an infectious agent.
    • RG1 agents are not associated with disease in healthy adult humans. Those agents not listed in Risk Groups (RG) 2, 3, and 4 are not automatically or implicitly classified in RG1; a risk assessment must be conducted based on the known and potential properties of the agents and their relationship to agents that are listed.
    • RG2 agents are associated with human disease which is rarely serious and for which preventive or therapeutic interventions are often available.
    • RG3 agents are associated with serious or lethal human disease for which preventive or therapeutic interventions may be available.
    • RG4 agents are likely to cause serious or lethal human disease for which preventive or therapeutic interventions are not usually available.