Cardiovascular Research Group

The Cardiovascular Research Group develops and applies novel MR imaging and analysis tools for the study of cardiovascular function and flow.

SPAMM

SPAMM (SPAtial Modulation of Magnetization) Simulated 3D tag data set

For studies of cardiac function, we have developed a rapid 4D tagged imaging sequence, which combined with 3D optical flow analysis (OFM) allows direct tracking of myocardial deformation. Accurate quantification of the motion and deformation of the intact myocardium is fundamental to understanding cardiac mechanics, improving diagnosis and developing treatments.

MR imaging has also been used to assess infarct size in vivo. From makers placed on the epicardial surface, infarct size is estimated from 3D models by integrating the volume bounded by the markers.

Whole heart high temporal and spatial resolution myocardial perfusion from MR first pass enhancement images are being applied to the study of myocardial infarction.

Many of the tools developed for our cardiovascular research have been applied to other applications such as breast DCE-MRI, lung perfusion, lung nodule detection and head and neck tumor classification.