Small Animal Imaging Facility - Services

To prevent the spread of disease among the general animal population, SAIF provides its own animal housing. Any animal, once scanned in any SAIF facility, may not be taken back to its original housing facility without going through quarantine.

There are two areas designated to hold SAIF animals. Our mouse area can presently hold a maximum of approximately 200 cages (5 mice/cage maximum). In addition, it has an isolation unit for another 40 cages. The rat holding area can hold about 75 cages (3 rats/cage maximum).

Animals are expected to be housed in SAIF only for longitudinal studies.

Completion of study:

After a study is completed, it is expected that the animals will be either euthanized or moved back into another housing facility after being quarantined. Animals destined to be euthanized immediately after scanning, may be transported from their non-SAIF housing to SAIF areas, scanned and appropriately euthanized.

Animal Husbandry:

Husbandry of animals is provided by ULAR

Radioactivity:

For animals being imaged using radioactive materials, two special rooms are provided to allow the radioactivity to decay safely. The radioactivity is monitored by SAIF staff. It is the responsibility of the investigator to provide for husbandry during this decay period as ULAR will not handle radioactive animals. Typically for PET pharmaceuticals, this period is only 24 hours. In case of questions, address them to Dr Richard Freifelder.

Facility Access:

Personnel access to all SAIF housing areas is granted on an "as needed" basis. All questions regarding housing, access, length of stay, etc., in SAIF housing should be addressed to Katie Malitsky (Katie.Malitsky@uphs.upenn.edu). Animals may be delivered directly to the housing areas but only with prior arrangement with SAIF staff and only if all applications, animal ordering request forms and protocols specifically call for the animals to be housed in SAIF.

High Risk Animals:

High risk animals require additional procedures and will be handled on a case by case basis.

Personal Protective Equipment:

All investigators are required to follow proper gowning procedures and to log animals in and out of SAIF housing. Failure to do so will result in loss of privileges. This is to insure the safety of all investigators animals. Please see SAIF SOP 2.01 for details.