Clinical Office - Patients
Perelman Center for Advanced Medicine
3400 Civic Center Blvd.
Suite 1-300S
Philadelphia, PA 19104
Phone: 215-662-2638
Fax: 215-349-5703
Research Faculty Office:
Room 305 CRB
415 Curie Boulevard
Philadelphia, PA 19104
Phone: 215-573-1830
Fax: 215-898-0189
Administration Office:
Hospital of the University
of Pennsylvania
Renal-Electrolyte &
Hypertension Division
One Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Phone: 215-662-7934
Fax: 215-615-0349
Deepak nihalani, ph.d.
ASSISTANT research PROFESSOR OF medicine
Business Address:
Hospital of the University of Pennsylvania
322 CRB
415 Curie Boulevard
Philadelphia, PA 19104
Board Certification: Internal Medicine and Nephrology
Research Interests:
Molecular movement in podocytes depends on Myo1c motor function
Clinical and Other Interests:
Selected References:
George B, Verma R, Soofi A, Garg P, Zhang J, Park T-J, Giardino L, Ryzhova L, Johnstone DB, Wong H, Nihalani D, Salant DJ, Hanks SK, Rastaldi M, Holzman, LM: Crk 1/2-dependent signaling is necessary for podocyte foot process spreading in mice. Journal of Clinical Investigation 2011.
Garg R, Peddada N, Sagar A, Nihalani D, Ashish F: Visual insight into how low pH alone can induce actin severing ability in gelsolin under calcium free conditions. The Journal of Biological Chemistry 286(23): 20387-97, Jun 2011.
Arif E, Wagner MC, Johnstone DB, Wong HN, George B, Pruthi PA, Lazzara MJ, Nihalani D: Motor protein myolc is a podocyte protein that facilitiates the transport of slit diaphragm protein neph1 to the podocyte membrane. Molecular and Cellular Biology 31(10): 2134-50, May 2011.
Wagner MC, Rhodes G, Wang E, Pruthi V, Arif E, Saleem MA, Wean SE, Garg P, Verma R, Holzman LB, Gattone V, Molitoris BA, Nihalani D: Ischemic injury to kidney induces glomerular podocyte effacement anddissociationof slit diaphragm proteins Neph1 and ZO-1. The Journal of Biological Chemistry 283(51): 35579-89, Dec 2008.
Garg P, Verma R, Nihalani D, Johnstone DB, Holzman LB: Neph1cooperates withnephrin to transduce a signal that induces actin polymerization. Molecular and Cellular Biology 27(24); 8698-712, Dec 2007.