Raymond r. townsend, M.D.
Professor of Medicine
Business Address:
University of Pennsylvania
One Founders
3400 Spruce Street
Philadelphia, PA 19104
Phone: 215-662-2638
Fax: 215-349-5703
Email: townsend@mail.med.upenn.edu
Education:
Undergraduate: LaSalle University,Philadelphia, PA
Degree: B.A.
Medical: Hahnemann Medical College, Philadelphia, PA
Degree: M.D.
Residency: Allegheny General Hospital, Pittsburgh, PA
Fellowship: Temple University, Philadelphia, PA
Board Certification: Internal Medicine, Nephrology, Clinical Pharmacology
Research Interests:
Raymond R. Townsend, MD, is a Professor of Medicine, an Associate Director of the federally funded Clinical & Translational Research Center at the University of Pennsylvania, and the Director of the Penn Hypertension program. He is currently a Principal Investigator in a 7-center U01 grant (DK-060984) to evaluate the role of demographic, humoral and genetic factors in the progression of kidney disease and the development and progression of cardiovascular disease in patients with chronic kidney disease. He is the P.I. of an R01 grant evaluating the specific role of pulse wave velocity in the renal and cardiovascular consequences of chronic kidney disease (DK-067390). He collaborates with Dr. Karen Teff (PhD) evaluating the role of the parasympathetic nervous system in insulin sensitivity, and the effects of glucose on novel humoral regulators of appetite and metabolism, including leptin, pancreatic polypeptide and gherelin. His clinical interests are in hypertension and metabolism. He is a Fellow of the American Heart Association and a Fellow of the Council for High Blood Pressure Research. He is a member of the NHLBI Joint National Committee (JNC8) and the chair of the American Heart Association’s 7th Hypertension Summer School (July 2010).
Selected References:
Townsend RR, Chirinos JA, Parsa A, Weir MA, Sozio SM, Lash JP, Chen J, Steigerwalt SP, Go AS, Hsu CY, Rafey M, Wright JT Jr, Duckworth MJ, Gadegbeku CA, Joffe MP; for the Chronic Renal Insufficiency Cohort Investigators. Central Pulse Pressure in Chronic Kidney Disease: A Chronic Renal Insufficiency Cohort Ancillary Study. Hypertension 2010;56(3):518-524. PMID 20660819 PMCID/NIHMSID 229327
Townsend RR, Wimmer NJ, Chirinos JA, Parsa A, Weir M, Perumal K, Lash JP, Chen J, Steigerwalt SP, Flack J, Go AS, Rafey M, Rahman M, Sheridan A, Gadegbeku CA, Robinson NA, Joffe M. Aortic PWV in Chronic Kidney Disease: A CRIC Ancillary Study. American Journal of Hypertension 2010;23:282-289
Muntner P, Anderson A, Charleston J, Chen Z, Ford V, Makos G, O'Connor A, Perumal K, Rahman M, Steigerwalt S, Teal V, Townsend R, Weir M, Wright JT Jr; Chronic Renal Insufficiency Cohort (CRIC) Study Investigators. Hypertension awareness, treatment, and control in adults with CKD: results from the Chronic Renal Insufficiency Cohort (CRIC) Study. American Journal of Kidney Diseases 2010;55(3):441-451
Scialla JJ, Leonard MB, Townsend RR, Appel L, Wolf M, Budoff MJ, Chen J, Lustigova E, Gadegbeku CA, Glenn M, Hanish A, Raj D, Rosas SE, Seliger SL, Weir MR, Parekh RS. Correlates of Osteoprotegerin and Association with Aortic Pulse Wave Velocity in Patients with Chronic Kidney Disease. Clinical Journal of the American Society of Nephrology 2011;6(11):2612-2619. PMID: 21940840
Townsend RR, Anderson AH, Chen J, Gadebegku CA, Feldman HI, Fink JC, Go AS, Joffe M, Nessel LA, Ojo A, Rader DJ, Reilly MP, Teal V, Teff K, Wright JT, Xie D. Metabolic Syndrome, Components, and Cardiovascular Disease Prevalence in Chronic Kidney Disease: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. American Journal of Nephrology 2011;33(6):477-484. PMID: 21525746
Townsend R, Bittar N, Rosen J, Smith W, Ramsay A, Chrysant SG, Weiss R, Pivodic A, Duquesroix B, Djian J. Blood pressure effects of naproxcinod in hypertensive patients. J Clin Hypertens (Greenwich) 2011;13(5):376-384. PMID: 21545399
Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutiérrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St. John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-o M, Kusek JW, Keane MG, Wolf M. Fibroblast growth factor 23 induces left ventricular hypertrophy. Journal of Clinical Investigation 2011;121(11):4393-4408. PMID: 21985788. PMCID: 3204831
Townsend RR. Attending rounds: a patient with drug-resistant hypertension. Clinical Journal of the American Society of Nephrology 2011;6(9):2301-2306. PMID: 21852665
DeLoach SS, Meyers KE, Townsend RR. Living donor kidney donation: another form of white coat effect. American Journal of Kidney Disease 2012;35(1):75-79.
R. R. Townsend. Analyzing the radial pulse waveform: narrowing the gap between blood pressure and outcomes. Curr.Opin.Nephrol.Hypertens. 16 (3):261-266, 2007.
R. R. Townsend, S. Kapoor, and C. B. Mcfadden. Salt intake and insulin sensitivity in healthy human volunteers. Clin.Sci.(Lond) 113 (3):141-148, 2007.
R. R. Townsend. Vascular compliance and arterial calcification: impact on blood pressure reduction. Current Opinion Nephrology and Hypertension 17:93-98, 2008.
R. R. Townsend. Stroke in chronic kidney disease: prevention and management. Clin.J.Am.Soc.Nephrol. 3 Suppl 1:S11-S16, 2008.
K.L. Teff, J. Grudziak, R.R. Townsend et al. Endocrine and metabolic effects of consuming fructose- and glucose-sweetened beverages with meals in obese men and women: influence of insulin resistance on plasma triglyceride responses J.Clin.Endocrinol.Metab. 94:1562-1569, 2009.
Townsend, R.R. Angiotensin and insulin resistance: conspiracy theory. Current Hypertension Reports 5:110-116, 2003.
Mulrow, C.D., Townsend, R.R. Guiding lights for antihypertensive treatment in patients with nondiabetic chronic renal disease: proteinuria and blood pressure levels? Annals of Internal Medicine 139 (4):296-298, 2003.
Townsend R.R., McFadden C.B., Ford, V., Cadee J.A. A randomized, double-blind, placebo-controlled trial of casein protein hydrolysate (C12 peptide) in human essential hypertension. American Journal of Hypertension 17(11 Pt 1):1056-8, 2004.
Cohen D.L., Townsend R.R., Clark T.W. Renal Artery Stenosis due to Fibromuscular Dysplasia in an 18-week Pregnant Female. Obstetrics & Gynecology 2005;105:1232-1235.