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Maria Reila Molina, MSN, CRNP
Cardiovascular Surgery

 
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Office:
Hospital of the University of Pennsylvania
Heart-Lung Transplant Nurse Practitioner
6 Silverstein, 3400 Spruce St.
Philadelphia, PA 19104
Office: 215-614-0329
Fax: 215-349-5798

Contact Information (internal use only)

maria.molina@uphs.upenn.edu

 

Maria R. Molina holds three national nursing certifications (board certified in Acute Care Nurse Practitioner, Adult Gerontology ACNP and Critical Care RN), and is also a Penn Certified Research Coordinator. Maria stands in a unique position at the nexus of cardiovascular medicine, pulmonary medicine, critical care and cardiothoracic surgery with research focus on outcomes of advanced heart failure therapies, and integration of practice-based studies into clinical practice (e.g. immunologic variances pre & post cardiothoracic transplantation, and mechanical circulatory support as bridge to transplantation). Maria is a recognized co-investigator of internationally funded (BRIGHT: Building Research Initiative Group: Chronic Illness Management and Adherence in Transplantation) initiatives to improve cardiothoracic transplant care using distance technology, and conducting cutting edge dyadic symptom management. She has authored and co-authored more than 60 impactful conference papers and abstracts with emphasis on NP roles in advocating early referral for advanced therapies, developing risk stratification strategies for pre & post cardiothoracic transplantation, and the national impact of NP making great strides in translating research to bedside through NP managed care interventions. Maria’s contributions to advancement of nursing science have been acknowledged by multiple honors and awards (2016 American Association of Nurse Practitioners State Award for Excellence and 2015 International Transplant Nursing Excellence Award), as well as invitations to present in national and international scientific sessions.

 
Appointments
 
 
 
 
 
 
 
 
 
 
Education/Training
2012 - 2013  Post Master’s Certificate in Teaching:
University of Pennsylvania, School of Nursing,
 
2006 - 2009 Master of Science in Nursing: Acute-Critical Care Nurse Practitioner
Rutgers, the State University of New Jersey, School of Nursing
Formerly: University of Medicine and Dentistry of New Jersey, School of Nursing
 
 
 
 
 
Memberships/Societies
2015 - present PCNP: Pennsylvania Coalition of Nurse Practitioners
 
2013 - present  AANP: American Association of Nurse Practitioners
 
2013 - present  AST: American Society of Transplantation
 
2012 - present ACRP: Association of Clinical Research Professionals: Greater Philadelphia Chapter
 
2011 - present ISHLT: International Society of Heart and Lung Transplant
 
2010 - present ITNS: International Transplant Nurses Society
 
2008 - 2013 AANP: American Academy of Nurse Practitioners
 
2008 - 2012 ACNP: American College of Nurse Practitioners
 
2008 - 2012 Sigma Theta Tau International (Honor Society of Nursing): Omicron Pi Chapter 
 
2004 - present AACN: American Association of Critical Care Nurses
 
Research
2016 - present Outcomes Research of ECMO (Extracorporeal Membrane Oxygenator) Recipients
This is a descriptive –retrospective analysis of the clinical outcomes and survival of ECMO recipients at The University of Pennsylvania. The population studied will be the patients who underwent ECMO (either Veno-Venous of Veno-Arterial) from 1/1/2005 to present.
 
2016 - present L-TOR (Lung Transplant Outcomes Research) Study
The purpose of this study is to describe and quantify the clinical outcomes and survival of lung transplant recipients (alone or in combination with concurrent heart, kidney, or liver transplantation) at the University of Pennsylvania from 1991 to present
 
2015 - present ROHT (Research Outcomes of Heart Transplant) Study
This study is a descriptive analysis of the clinical outcomes, survival of heart transplants recipients (combined with other solid organ such as: kidney, liver, and lung), and identify risk stratification strategies in preventing transplant related complications and co-morbidities. The population studied will be the patients who received a heart transplant from 1996 to present.
 
2014 - present ORDER (Outcomes Research of Drug interactions and Economic Relationship) Study
This is a retrospective-chart review of pharmacological outcomes research of immunosuppressive medications, immunomodulators, antibiotics, antivirals, antifungals, antihypertensive, antihyperlipidemia, parenteral nutrition and other drug related medication-interactions and their economic impact to patient who had ventricular assist device (VAD) and received heart transplant from 1996-present
 
2013 - 2015  BRIGHT (Building Research Initiative Group: Chronic Illness Management and Adherence in Transplantation)
Penn Transplant Institute Research Liaison/ Site Coordinator                        
This study is Penn Heart Transplant Institute’s collaboration with the Institute of Nursing Science of the University of Basel (Switzerland), the Center of Health Services and Nursing Research of the University of Leuven (Belgium), and the   International Transplant Nurses Society (ITNS).
 
Publications
  1. Ticehurst, EH; Molina, MR; Kearns, J; Goldberg, LR; Tsai, D; Wald, JW; Kamoun, M. Antibody-mediated rejection in heart transplant recipients: long term follow-up of patients with high levels of donor-directed anti-DQ antibodies. Human Immunology 2011; 72(s1): s94.
  2. Molina, MR; Ticehurst, EH; Goldberg, LR; Chojnowski, D; Hornsby, N; Forfia, P.  Echo-Doppler Profile of Abnormal Right Ventricular-Pulmonary Arterial Interaction Is Associated with Beneficial Response in Heart Transplant Recipients with Pulmonary Hypertension.  J Heart and Lung Transplantation. Apr 2012; 31 (4S): S128 (360).
  3. Vallabhajosyula, P; Komlo, C; Molina, MR;  Roche, L; Kim,Y;  Goldberg, LR; Pochettino, A.  Combined Heart-Liver Transplantation (HLT) for Failed Single Ventricle/Fontan Physiology. J Heart and Lung Transplantation Apr 2012; 31 (4S): S112 (314).
  4. Frank, R; Molina, MR, Wald, JW; Goldberg, LR; Kamoun, M; Lal, P. Immunologic Variances Are Associated with the Development of Cardiac Allograft Vasculopathy. Am J of Transplantation Jun 2012; 12 (2S): 1205.
  5. Javaheri,A; Zamani,P;  Molina,MR; et al, and Rader, DJ. Increased Cholesterol Efflux Capacity is Associated with Improved Survival in Heart Transplant Recipients.Journal of Cardiac Failure. 08/2014; 20(8S):S81. DOI: 10.1016/j.cardfail.2014.06.231
    Frank, R; Molina, MR, Wald, JW; Goldberg, LR; Kamoun, M; Lal, P. Correlation of Circulating Donor Specific Anti-HLA Antibodies and Presence of C4d in Endomyocardial Biopsy with Heart Allograft Outcomes: A Single Center Retrospective Study. J Heart and Lung Transplantation, Apr 2013; 32 (4): 410-417
  6. Brisco, MA; Vorovich, E; Molina, MR; Testani, JM. Substantial Recovery of Renal Function is Uncommon Early Post Cardiac Transplant Irrespective of Pre-transplant LVAD Support. J Heart and Lung Transplantation Apr 2013; 32 (4S): S272 (756).
  7. Okada, DR; Molina, MR; Vorovich, EE; Han, Y. Assessment of Left Ventricular Function by Transthoracic Echocardiography following Orthotopic Heart Transplant. Journal of the American Society of Echocardiography, 2013 26(6): B33-34
  8. Frank, R; Molina, MR, Wald, JW; Goldberg, LR; Kamoun, M; Lal, P. Circulating Donor-Specific Anti–Human Leukocyte Antigen Antibodies and Complement C4d Deposition Are Associated with the Development of Cardiac Allograft Vasculopathy. American Journal of Clinical Pathology 2014 142:809-815
  9. Kamoun, M; Kearns, J; Molina, MR, Byui, M; Wald, JW, Capolla, T, and Goldberg, LR. Successful Outcomes of Combined Heart-Liver Transplant Across Pre-Formed High Levels of Donor Specific HLA Antibodies. Human Immunology 10/2014; 75:26-27. DOI:10.1016/j.humimm.2014.08.033
  10. Frank, R; Dean, S; Molina, MR, Kamoun, M; Lal, P. Correlations of lymphocyte subset infiltrates with donor specific antibodies and acute antibody mediated rejection in endomyocardial biopsies. Clinical Pathology, nov, 2014; DOI: 10.1016/j.carpath.2014.11.001
  11. Okada DR, Molina MR, Kohari M, Vorivich EE, Owens A, and Han Y. Clinical echocardiographic indices of left ventricular diastolic function correlate poorly with pulmonary capillary wedge pressure at 1 year following heart transplantation. International Journal of Cardio Imaging, online Feb. 16, 2015; The International Journal of Cardiovascular Imaging 02/2015; DOI: 10.1007/s10554-015-0624-z
  12. Vorovich, E., Molina, MR., Claridge, T., Williams, M., Chambers, S., Gearhart, C. . . . Zamani, P. Use of Basiliximab is Associated with Similar Outcomes Post Orthotopic Heart Transplantation: A Single Center Experience. Journal of Cardiac Failure August 2015, 21(8), S40-S41.
  13. Chen J, Stein S, Molina MR, Owens A, Han Y. Right heart size in orthotopic heart transplant population: Influence of donor and recipient gender, race, and body surface area. Int J Cardiol. 2015 Oct 8; 203:105-106 doi:10.1016/j.ijcard.2015.10.066
  14. Javaheri, A., Zamani, P., Molina, MR, Rodrigues, A., Chambers, S., Stutman, P., Maslanek, W., Williams, M.., . . .and Rader, DJ. Correlation of improved cholesterol efflux capacity of high density lipoprotein with survival and allograft vasculopathy in cardiac transplant recipients.Arteriosclerosis, Thrombosis, and Vascular Biology 2015, 35(Suppl 1), A540-A540
  15. Frank, R; Lal, P; Kearns, J; Molina, MR; et al. and Kamoun, M. Correlation of Circulating Complement-Fixing Donor-Specific Antibodies Identified by the C1q Assay and Presence of C4d in Endomyocardial Biopsy Specimens. American Journal of Clinical Pathology 145(1):62-68 · January 2016. DOI: 10.1093/ajcp/aqv016
  16. Birati, EY; Mathelier, H; Molina, MR, et. al. and Jessup, M. Comparison of Causes of Death After Heart Transplantation in Patients with Left Ventricular Ejection Fractions ≤35% Versus >35. The American journal of cardiology 117(8) · January 2016. DOI: 10.1016/j.amjcard.2016.01.028
  17. Menachem, J; Golbus, J; Molina, MR; et al.a nd Wald, J. Successful Cardiac Transplantation Outcomes in Patients with Adult Congenital Heart Disease: A Team Based Approach. Journal of the American College of Cardiology 67(13):1446 · April 2016. DOI: 10.1016/S0735-1097(16)31447-4
  18. Javaheri, A.; Molina, MR; Zamani, P; et al. and Rader, DJ. Cholesterol efflux capacity of high-density lipoprotein correlates with survival and allograft vasculopathy in cardiac transplant recipients.The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation · July 2016. DOI: 10.1016/j.healun.2016.06.022
  19. Reza, N; Menachem, J; Molina, MR; et al & Goldberg, LR. Cardiopulmonary Exercise Testing in Adults with Congential Heart Disease Underestimates Disease Prior to Cardiac Transplantation. Journal of Cardiac Failure August 2016 DOI: 10.1016/j.cardfail.2016.06.37
  20. Hanff, TC; Molina, MR; Owens, AT; et al. and Birati, EY. Body Mass Index and Survival in Orthotopic Heart Transplant Patients. Journal of Cardiac FailureAugust 2016. DOI: 10.1016/j.cardfail.2016.06.398
  21. Molina, MR; Yelavarty, P; Chojnowski, D; et.al, and Forde-McLean, R. Simulect for Induction in Heart Transplant Patients -the Double-Edged Sword. Journal of Cardiac Failure August 2016. DOI: 10.1016/j.cardfail.2016.06.393
  22. Padegimas, A, Molina, MR, Korwin, A, Birati, EY, and Kamoun, M. Successful long term outcomes in combined heart-liver transplants across preformed high levels of donor specific antibodies in highly sensitized patients. October 2016, DOI: 10.1016/j.healun.2016.09.012
  23. Menachem, J, Golbus, JR, Molina, MR, …. et al and Wald, JW. Successful cardiac transplantation outcomes in patients with adult congenital heart disease. Heart (British Cardiac Society) · March 2017
    DOI: 10.1136/heartjnl-2016-310933
  24. Courthwright, A, Zaleki,D, Ahya, V, et al…. Molina, MR and Diamond, J. Causes and Preventability of Unplanned Rehospitalization Following Lung Transplantation.  April, 2017. DOI: 10.1016/j.healun.2017.01.1429
  25. Bermudez, CA, Molina, MR, Thomasson, A, Blumberg, E…. et al and Crespo, MM. Lung Transplant Experience with Public Health Services (PHS) “Increased Risk Donors”: Recipient Outcomes and Incidence of Transmission and Conversion. April, 2017. DOI: 10.1016/j.healun.2017.01.125
  26. Bermudez, CA, Molina, MR, Goldberg, LR.. et al and Acker, MA. Incidence and Implications of Primary Graft Dysfunction (PGD) in heart transplantation using the ISHLT Consensus Criteria. April, 2017. DOI:10.1016/j.healun.2017.01.1133
  27. Lim, B, Lasky, J, Shaufler, C, etal….. Molina, MR and Cantu,E. Lung Allocation Score Implementation Narrowed Racial/Ethnic Disparities in Adult Lung Transplantation Outcomes. April, 2017. DOI: 10.1016/j.healun.2017.01.033
  28. Gentile, J, Molina, MR, Atluri, P,… et al and Bermudez, CA. ECMO use in INTERMACS 1 patients as a Bridge to LVAD with Intention to Transplant versus Bridge to Direct Heart Transplant: Single Center Experience. April, 2017. DOI: 10.1016/j.healun.2017.01.943
Book Chapter Publication
  1. Ticehurst, EH; Molina,  MR;  Frank,  R;  Kearns,  J; Lal,  P; Goldberg, LR; Tsai, D; Wald ,JW; Kamoun,  M. Antibody-mediated rejection in heart transplant recipients: long term follow-up of patients with high levels of donor-directed anti-DQ antibodies.  In:  Checka, JM and Terasaki PI, editors. Clinical Transplants 2011: 409-414. Los Angeles, UCLA Tissue Typing Laboratory, 2012.
  2. Cardiovascular Nursing: Scope and Standards of Practice 2nd edition
    American Nurses Association for American Nurses Publishing
    Molina, MR. Co-author/contributor; PUB. DATE July 2015; ISBN: 9781558106239; PUB# 9781558106239
 
Awards
2017 Best Research Abstract Award: International Transplant Nurses Society (ITNS) 
“Plasmapheresis and Desensitization Therapies for Solid Organ Transplantation” 
26th Transplant Nursing Symposium, June 26, 2017, Lake Buena Vista, Florida
 
2016 Most Published Advanced Practitioner: University of Pennsylvania Health System
Advanced Practice Provider Annual Recognition, October 27, 2016
 
2016  TOP Best Research Abstract Award: International Transplant Nurses Society (ITNS) 
“Building an Infrastructure for Interprofessional Collaborative Patient Centered
Outcomes Research,” 25th ITNS Conference, Pittsburg, PA, October 16, 2016 
 
2016 American Association of Nurse Practitioners State Award for Excellence in Clinical Practice
AANP Conference, San Antonio, Texas, June 21-26, 2016
 
2015 Rutgers University Nursing Alumni Rising Star Award
Rutgers School of Nursing Alumni Association (RSONAA)
Annual RSONAA Awards Celebration Event, October 20, 2015, Grand Summit Hotel, NJ
 
2015 TOP Best Research Abstract Award:International Transplant Nurses Society (ITNS)
Right Ventricle Failure: Is it Pulmonary or Portal Hypertension?
24th ITNS Conference, Chicago, June 14, 2015.
 
2015 Transplant Nursing Excellence Award: International Transplant Nurses Society (ITNS)
24th ITNS Conference, Chicago, June 14, 2015.
University of Pennsylvania Health System, APP Annual Recognition, October, 2014
 
2014 Penn Advanced Practice Providers’ (APP) Inaugural Best Clinical Practice
“March Madness Tournament Winner”
Heart Transplant Team, Hospital of University of Pennsylvania
University of Pennsylvania Health System, APP Annual Recognition, October, 2014
 
2014 TOP Best Research Abstract Award:International Transplant Nurses Society (ITNS)
Cardiac Allograft Vasculopathy: An Accelerated Form of Coronary Artery Disease
23rd   ITNS Conference, Houston, Texas, September 27-29, 2014
 
2009 Magna Cum Laude, Rutgers University, the state University of New Jersey (formerly UMDNJ)
 
2008 Margaret Doherty Scholarship Award, Sigma Theta Tau International:
Omicron Pi  Chapter, UMDNJ: University of Medicine and Dentistry of New Jersey

Maria Molina

 
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