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Joshua I. S. Bleier, M.D.
Colon and Rectal Surgery

 
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Administrative Office:
Pennsylvania Hospital
800 Walnut Street, Floor 20
Philadelphia, PA 19107
Administrative Assistant: Charmaine Briggs
Administrative Telephone: 215 454- 3204
Administrative Fax: 215-829-5350
Patient Appointments: 215-829-5333

Clinical Offices:
Pennsylvania Hospital
800 Walnut Street, Floor 20
Philadelphia, PA 19107
Clinical Telephone: 215-829-5333
Clinical Fax: 215-829-5350

Perelman Center for Advanced Medicine
West Pavilion, 4th Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Telephone: 215-829-5333
Clinical Fax: 215-829-5350

Contact Information (internal use only)

joshua.bleier@uphs.upenn.edu

 

Dr. Joshua Bleier is board certified in Colon and Rectal and General Surgery. He attended The University of Pennsylvania for both his undergraduate and medical degrees. He received his General Surgery training at Cornell, and completed a research fellowship in Immunology at Memorial Sloan-Kettering Cancer Center. He completed his Colon and Rectal Training at the University of Minnesota.

Dr. Bleier is the Section Chief of Colon and Rectal Surgery at Pennsylvania Hospital, and is the Associate Program Director for the Clorectal Fellowship. In addition, he is the Clerkship Director for the medical Student Surgical Curriculum.

Dr. Bleier’s practice spans the range of colon and rectal disease. He specializes in the management and treatment of benign diverticular disease and Colon and rectal Cancer with both standard and minimally invasive approaches, included laparoscopy and robotics, with an emphasis on sphincter-preservation. His areas of specialty also include the surgical treatment of Inflammatory Bowel Disease, as well as the spectrum of benign anorectal and pelvic floor disorders, Including sacral nerve stimulation for fecal incontinence. His practice includes colonoscopy, as well as advanced techniques for local treatment of early rectal polyps and cancers using Transanal Endocscopic Microsurgery (TEM).

 
Faculty Appointments
2014 - present  Associate Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2008 - 2014 Assistant Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2001 - 2002 Clinical Associate in Surgery
Weill Medical College of Cornell University
New York, New York
 
2006 - 2007 Senior Clinical Associate in Surgery
Weill Medical College of Cornell University
New York, New York
 
Hospital and Administrative Appointments
2013 - present Section Chief of Colorectal Surgery
Pennsylvania Hospital
 
2013 - present Associate Program Director
Colorectal Fellowship
 
2013 - present Clerkship Director
Introductory Surgical Clerkship (SU200)
 
2009 - present  Attending Surgeon
Veterans Administration Medical Center (VAMC)
Philadelphia, Pennsylvania
 
2008 - present   Attending Surgeon
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2008 - present Attending Surgeon
Pennsylvania Hospital
Philadelphia, Pennsylvania
 
2008 - present  Attending Surgeon
Presbyterian Medical Center
Philadelphia, Pennsylvania
 
2000 - 2002 Assistant Surgeon
New Presbyterian Hospital/Weill Medical Center
New York, New York
 
2002 -2003 Fellow in Surgery
Weill Medical College of Cornell University
New York, New York
 
2003 - 2004 Administrative Chief Research Fellow
Memorial Sloan-Kettering Cancer Center
New York, New York
 
2004 - 2007 Assistant Surgeon
New Presbyterian Hospital/Weill Medical Center
New York, New York
 
Education/Training
1996 - 2000 M.D. University of Pennsylvania School of Medicine
 
1992 - 1996 B.A. University of Pennsylvania College of Arts & Sciences (Biology)
 
Postgraduate Training and Fellowship Appointments
2007 - 2008 Fellow in Colon & Rectal Surgery
University of Minnesota Medical Center
St. Paul, Minnesota
 
2004 - 2007 Categorical Resident in Surgery
New York Presbyterian Hospital/ Weill Medical Center
New York, New York
 
2002 - 2004 Clinical Fellow in Surgery
New Presbyterian Hospital/Weill Medical Center
New York, New York
 
2002 - 2004 Research Fellow
Memorial Sloan-Kettering Institute for Cancer Research
New York, New York
 
2000 - 2002 Categorical Resident in Surgery
New York Presbyterian Hospital/ Weill Medical Center
New York, New York
 
Memberships/Societies
 
National/International Societies
  American Association for Cancer Research
 
  Fellow, American College of Surgeons
 
  Fellow, American Society of Colon and Rectal Surgeons
 
  American Society of Colon & Rectal Surgeons
 
  Society for American Gastrointestinal and Endoscopic Surgeons
 
  The Society of Laparoendoscopic Surgeons
 
  Association for Surgical Education
 
Local/Regional Societies
  Pennsylvania Colorectal Society, Board Member
2012 – 2013,  Member-at-large
2013 – 2014,  Historian
2014 – 2015, Secretary
 
  Philadelphia Academy of Surgery, Fellow
 
  Abramson Cancer Center of the University of Pennsylvania
Cancer Therapeutics Research Program, Associate Member 
 
Research
 
Clinical Trials
NCT01602081: Site Principal Investigator, Ligation of the Intersphincteric Fistula Tract  (LIFT) + Biodesign for Anal Fistula (LIFT+Graft) (CLOSED Jan 2014)
 
SMG1108: Site Principal Investigator, A Randomized, Prospective, Multi-centered Study Comparing Clinical Outcomes of the Ligation of Intersphincteric Fistula tract (LIFT) Procedure versus Use of an Anal Fistula Plug (AFP) in the Surgical Repair of Trans-sphincteric Anal Fistulae of Cryptoglandular Origin. (CLOSED Jan 2011)
 
 
 
 
 
Publications
 
Research Publications, Peer Reviewed
  1. Bleier JI, Krupnick AS, Kreisel D, Song HK, Rosato EF, Williams NN.  Hand-assisted laparoscopic vertical banded gastroplasty: early results.  Surgical Endoscopy 14(10):902-907, Oct. 2000.
  2. Weyant MJ, Bleier JI, Naama H, Eachempati SR, Schiff J, Barie PS, Yankelevitz DF. Severe crushed chest injury with large flail segment: computed tomographic three-dimensional reconstruction.  Journal of Trauma-Injury Infection & Critical Care. 52(3):605, Mar. 2002.
  3. Marshall MB, Deeb ME, Bleier JI, Kucharczuk JC, Friedberg JS, Kaiser LR, Shrager JB. Suction vs water seal after pulmonary resection: a randomized prospective study.  Chest 121(3):831-835, Mar. 2002.
  4. Pillarisetty VG, Shah AB, Miller G, Bleier JI, DeMatteo RP.  Liver dendritic cells are less immunogenic than spleen dendritic cells because of differences in subtype composition.  Journal of Immunology 172(2):1009-1017, Jan. 15, 2004.
  5. Sarkaria IS, Eachempati SR, Weyant MJ, Hydo LJ, Barie CA, Bleier JI, Boffa DJ, Barie PS.  Current surgical opinion of computed tomography for acute appendicitis.  Surgical Infection 5(3):243-252, May 2004.
  6. Miller G, Bleier JI, Antonescu C, Pillarisetty VG, Shah AB, Lahrs S, DeMatteo RP. Natural killer cell depletion confounds the antitumor mechanism of endogenous IL-12 overexpression.  International Journal of Cancer 110(3):395-402, June 20, 2004.
  7. Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP.  Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.  Journal of Immunology 172(12):7408-7416, June 15, 2004.
  8. Katz SC, Pillarisetty VG, Bleier JI, Shah AB, DeMatteo RP.  Liver sinusoidal endothelial cells are insufficient to activate T cells.  Journal of Immunology 173(1):230-235, July 1, 2004.
  9. Pillarisetty VG, Katz SC, Bleier JI, Shah AB, DeMatteo RP.  Natural killer dendritic cells have both antigen presenting and lytic function and in response to CpG produce IFN-gamma via autocrine IL-12.  Journal of Immunology 174(5):2612-2618, Mar. 1, 2005.
  10. Katz SC, Pillarisetty VG, Bleier JI, Kingham TP, Chaudhry UI, Shah AB, DeMatteo RP. Conventional liver CD4 T cells are functionally distinct and suppressed by environmental factors.  Hepatology 42(2):293-300, Aug. 2005.
  11. Bleier JI, Katz SC, Chaudhry UI, Pillarisetty VG, Kingham TP 3rd, Shah AB, Raab JR, DeMatteo RP.  Biliary obstruction selectively expands and activates liver myeloid dendritic cells.  Journal of Immunology 176(12):7189-7195, June 15, 2006.
  12. Bleier JI, Moon V, Feingold, Whelan RL, Arnell T, Sonoda T, Milsom JW, Lee SW. Initial repair of iatrogenic colon perforation using laparoscopic methods. Surgical Endoscopy 22(3):646-649, Mar. 2008.
  13. Menon C, Bauer TW, Kelley ST, Raz DJ, Bleier JI, Patel K, Steele K, Fraker DL.  Tumoricidal activity of high-dose tumor necrosis factor alpha is mediated by macrophage-derived nitric oxide burst and permanent blood flow shutdown.  International Journal of Cancer 123(2):464-475, July 15, 2008.
  14. Nash G, Bleier J, Milsom J, Trencheva K, Sonoda T, Lee S. Minimally invasive surgery is safe and effective for urgent and emergent colectomy. Colorectal Disease. 2010 May;12(5):480-4.
  15. Bleier JI, Moloo H, Goldberg SM. Ligation of the Intersphincteric Fistula Tract (LIFT): An effective new technique for complex fistulae. Diseases of the Colon and Rectum. 2010 Jan;53(1):43-6.
  16. Bleier JIS, Moloo H. Current management of cryptoglandular fistula-in-ano. World J Gastroenterol 2011; 17(28):3286-91.
  17. Glasgow SC, Bleier JI, Burgart LJ, Finne CO, Lowry AC. Meta-analysis of Histopathologic Features of Primary Colorectal Cancers that Predict Lymph Node Metastases. J Gastrointest. Surg. 2012; 16(5): 1019-28.
  18. Mollo EA, Reinke CE, Nelson C, Holena DN,  Kann B, William NN, Bleier JI,  Kelz RR. The Simulated Ward: Ideal for Training Clinical Clerks in an Era of Patient Safety.  J Surg Res. 2012; 177(1): e1-6.
  19. Hatch Q, Champagne B, Maykel J, Davis B, Johnson E, Bleier J, Francone T, Steele S. Crohn’s Disease and Pregnancy: The Impact of Perianal Disease on Delivery Methods and Complications. Dis Colon Rectum. 2013; In press

Abstracts

  1. “Laparoscopic Surgery for Recurrent Crohn’s Disease.”  (with Lee SW, Sonoda T, Milsom JW.)  New York Society of Colon & Rectal Surgeons, New York, NY (March 2007)
  2. “Martius Flap Repair of Complex Rectovaginal Fistulas.”  (with Lee AE, Mellgren AF, Madoff RD, Lowry AC.) American Society of Colon and Rectal Surgeons, Annual Meeting and Tripartite Meeting, Boston, MA (June 2008)
  3. “Salvage Coccygectomy for Refractory Coccydynia is a Safe and Effective Treatment.”  (with Lee AE, Mellgren AF, Spencer MP.) American Society of Colon and Rectal Surgeons, Annual Meeting and Tripartite Meeting, Boston, MA. June 2008.
  4. M“The impact of infliximab on the indications for surgery in ulcerative colitis.” (with Mahmoud N, Aberra F). American Society of Colon and Rectal Surgeons, Annual Meeting May 2011.
Editorials, Reviews, Chapters, Participation in Committee Reports (print or other media)
  1. Bleier JI, Townsend: Sabiston Textbook of Surgery, 18th Edition. Online update to Chapter on Colon and Rectum
  2. Bleier JI, Resnick A, Mahmoud, N. Seminars in Colon and Rectal Surgery: Ventral Hernia Repair. Chapter, “Complications of Ventral Hernia”. 2009
  3. Bleier JI, Invited Review of Anorectal Melanoma. Journal of Gastroenterology and Hepatology, July 2009.
  4. Bleier JI, Fry RD. Maingot’s Abdominal Operations. Chapter 42, Cancer of the Anus, 12th Ed. 2009
  5. Hedrick T, Bleier JI, Steele S. Clinics in Colon and Rectal Surgery: Metabolic Support of the Enterocutaneous Fistula Patient. Volume 23, 2010.
  6. Bleier JI, Moloo H. Seminars in Colon and Rectal Surgery: Advances in Colorectal Surgery: Management of Cryptoglandular Fistula-in-Ano. 22(1); 9-14.
  7. Bleier JI, Moloo H. Netter’s Surgical Anatomy and Approaches: Sites of Perirectal Abscess, Fistula in Ano. Saunders, 2013. Edited by Conor Delaney.
  8. Moloo H, Bleier JI, Steele S.  Seminars in Colon and Rectal Surgery: Current management of Colonic Diverticular Disease: Surgery for Complicated Diverticulitis. 22(3); 157-161.
  9. Bleier JI, Moloo H, Goldberg SM. Master Techniques in Colon and Rectal Surgery. Chapter, “Ligation of the Intersphincteric Fistula Tract: the LIFT Procedure.” 2012.
  10. Fry RD, Mahmoud NN, Maron DJ, Bleier JI. Sabiston Textbook of Surgery, 19th Edition. Chapter 52: Colon and Rectum. Elsevier, 2012.
  11. Lewis R, Bleier JI, Kann B. Clinics in Colon and Rectal Surgery: Anorectal Crohn’s Disease. 26(2): 90-99.  2013.
  12. Bleier JI, Fry RD. Complexities in Colon and Rectal Surgery: Decision-Making and Management. Section 5, Chapter 24: Considerations in the Elderly. Springer, 2014, forthcoming.
  13. Aarons C, Bleier JI, Stein S. Clinics in Colon and Rectal Surgery: Surgical Clinic Guidelines for Peri-Operative Care: Fluid Restriction. 26(3): 197-202. 2013
  14. Bleier JI, Maykel J, Steel S. Surgical Clinics of North America: Complications, Considerations, and Consequences of Colorectal Surgery: Life after Proctectomy. Elsevier, 93(1) 89-106. 2013.
  15. Bleier JI, Kann B, Alavi K. Clinics in Colon and Rectal Surgery: Faculty Development in Academic Surgery; Academic Goals. 26(4): 212-217. 2013.
  16. Bleier JI, Kann B, Steele SR. Minimally Invasive Approaches to Colon and Rectal Disease: Technique and Best Practices; Laparoscopy in the Elderly. Springer Publishing. In press.
  17. Shanmugan S, Bleier JI, Francone T.  Seminars in Colon and Rectal Surgery: Anastomotic Leak: The ideal Bowel Prep. In press
Books
  1. Blackbourne L, ed.; Bleier J, Assoc. Ed.  Surgical Recall, 4th Edition.  Philadelphia: Lippincott Williams & Wilkins, 2005
Alternative Media
  1. Bleier J, Tuite C, Baum R.  A striking radiographic example of bronchial hemorrhage.  SCVIR Case Club (on-line), Case No. 1299-02, 1999.
  2. Bleier J, Roberts D, Wu S, Baum R, Haskal Z.  Inadvertent arterial placement of subclavian central venous catheter.  SCVIR Case Club (on-line), 7:6, 1999.
 
Awards, Honors and Membership in Honorary Societies
2008  Carl Christenson, MD Award for Outstanding Resident Scholar
University of Minnesota, Colon and Rectal Surgery Fellowship
 
2003 - 2004 Administrative Chief Research Fellow, Memorial Sloan-Kettering Cancer Center
 
2000 Alpha Omega Alpha Honor Society
 
2000 I.S. Ravdin Prize for Excellence as a Surgical Student
University of Pennsylvania School of Medicine
 
1996 Benjamin Franklin Scholar, University of Pennsylvania School of Arts & Sciences
 
 

Dr. Joshua Bleier

 
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