penn medicine
penn surgery
penn surgery home penn surgery clinical penn surgery education penn surgery research penn surgery administration

Edward Cantu, III, M.D.
Cardiovascular Surgery

 
  • Profile Home
  • Appointments
  • Education
  • Societies
  • Research
  • Publications
  • Awards

Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
6 Silverstein Pavilion
Philadelphia, PA 19104
Administrative Assistant: Julianne Davis
Administrative Telephone: 215-615-6582
Administrative Fax: 215-349-5798

Clinical Office:
Perelman Center for Advanced Medicine
Heart & Vascular Center
East Pavilion, 2nd floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Telephone: 215-615-6582
Clinical Fax:
215-349-5798

Contact Information (internal use only)

edward.cantu@uphs.upenn.edu

 

Dr. Cantu is an Assistant Professor of Surgery at the Hospital of the University of Pennsylvania and the Presbyterian Medical Center of Philadelphia and the Pennsylvania Hospital and is the Associate Surgical Director of Lung Transplantation, Director of Ex Vivo Lung Perfusion Center, Hospital of the University of Pennsylvania.

 
Faculty Appointments
2010 - present Assistant Professor of Surgery at HUP, PPMC & PAH
Perelman School of Medicine, Philadelphia, Pennsylvania
 
Hospital and Administrative Appointments
2014 - present   OPTN/UNOS Chairman for the Ad Hoc Committee, third party perfusion regulation
 
2013 - present  OPTN/UNOS Membership and Professional Standards Committee (MPSC) Member
 
2012 - present  Interim Surgical Director of Lung Transplantation
Hospital of the University of Pennsylvania
 
2012 - present International Society of Heart and Lung Transplantation Registry and Database
Working Group
 
2012 - present Surgical Director of Lung Transplantation
Hospital of the University of Pennsylvania
 
2011 - present The Gift of Life Donor Program Medical Advisory and Policy Board member
 
2010 - present Attending Surgeon
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
 
2010 - present Active Surgeon
Penn Presbyterian Medical Center, Philadelphia, Pennsylvania
 
2010 - present Active Surgeon
Pennsylvania Hospital, Philadelphia, Pennsylvania
 
2010 - present Assistant Professor of  Surgery, Associate Surgical Director of Lung Transplantation
Director of Ex Vivo Lung Perfusion Center
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
 
2007 - 2010  Cardiothoracic Surgery Resident,  Duke University Medical Center
Durham, North Carolina
 
2006 - 2010 Consultant, Duke Clinical Research Institute
Durham, North Carolina
 
2004 - 2008 Advanced Trauma and Life Support Instructor, Duke University Medical Center
Durham, North Carolina
 
2002 - 2004 Instructor, Physician Assistant Program, Duke University Medical Center
Durham, North Carolina
 
2002 - 2004 NIH NRSA Fellow, Duke University Medical Center
Durham, North Carolina
 
1997 - 1998 House Officer of Research, Columbia University
New York, New York
 
1996 - 1997 American Heart Association Research Fellow, Columbia University
New York, New York
 
1995 Mayo Clinic Summer Research Fellow
Rochester, Minnesota
 
Education/Training
1994 - 2000 MD - Columbia University College of Physicians and Surgeons
New York, New York
 
1990 - 1994 BA - Harvard University
Cambridge, Massachusetts (Biology)
 
Postgraduate Training and Fellowship Appointments
2000 - 2001 Internship, General and Thoracic Surgery
Duke University Medical Center
Durham, North Carolina
 
2001 - 2002 Junior Assistant Resident
General and Thoracic Surgery
Duke University Medical Center
Durham, North Carolina
 
2002 - 2004 Research Fellow in Thoracic Transplantation
Duke University Medical Center
Durham, North Carolina
 
2004 - 2006 Senior Assistant Resident in General and Thoracic Surgery
Duke University Medical Center
Durham, North Carolina
 
2006 - 2007 Chief Resident in General and Thoracic Surgery
Duke University Medical Center
Durham, North Carolina
 
2007 - 2010 Cardiothoracic Surgery Resident
Duke University Medical Center
Durham, North Carolina
 
Memberships/Societies
 
National/International Societies
2007 - present American College of Chest Physicians
 
2007 - present American Society of Transplant Surgeons
 
2002 - present American College of Surgeons
 
1994 - present American Medical Association
 
 
Research
7/1/2014 - 7/1/2019 TSFRE: Thoracic Surgery foundation for research and education
Role: Principal Investigator
Title: "Lung Transplant Donor: Prediction, Evaluation, and Mechanism"
 
7/1/2014 - 1/1/2016 NIH, LRP
Role: Principal Investigator
Title: “Lung Transplant Donor: Prediction, Evaluation and Mechanism”
 
7/1/2013 – 7/1/2017 Harold Amos Medical Faculty Development Program Award
Role: Principal Investigator
Title: Ex vivo lung perfusion donor selection and enhanced recovery
 
2/2013 - 2/2018 NIH K23
Role: Principal Investigator
Title: Lung transplant donor: prediction, evaluation and mechanism
 
6/1/2011 – 7/1/2018 Philadelphia Antiques Show
Role: Principal Investigator
Title: Ex Vivo Lung Perfusion
 
7/15/2011 - 7/15/2012 McCabe Pilot Award
Role: Principal Investigator
Title: Pre-operative Donor Predictive Gene Expression Signature in Lung Transplantation
 
7/1/2007 - 7/1/2012 American Society of Transplant Surgeons
Role: Co-Principal Investigator
Title: Prospective Registry of Outcomes in Patients Electing Lung Transplantation (PROPEL): A correlative analysis using gene signature array
 
7/1/2007 - 7/1/2009 NIH, LRP
Role: Investigator
Title: Gene Expression Signatures of Oncogenic Pathway Deregulation in Non-Small Cell Lung Cancer
 
7/8/2002 - 7/7/2004 NIH, 1F32HL071457-01, 5F32HL071457-02
Role: Investigator
Title: Role of coagulation and pulmonary xenograft injury
 
7/1/1997 - 7/1/1998 NIH, 3R01HL042507-08S1
Role: Investigator
Title: Modulation of Endothelial Cell Function by Hypoxia
 
7/1/1996 - 7/1/1997 American Heart Association
Role: Investigator
Title: Hyperacute Rejection in Xenotransplantation
 
Publications
Research Publications, Peer Reviewed
  1. O'Hair DP, Cantu E, McGregor C, Jorgensen B, Gerow-Smith R, Galantowicz ME, Schulman LL. Preliminary experience with mycophenolate mofetil used after lung transplantation. J Heart Lung Transplant 1998;17(9):864-8.
  2. Maruyama S, Cantu E, 3rd, Demartino C, Vladutiu A, Caldwell PR, Wang CY, D'Agati V, Godman G, Stern DM, Andres G. Membranous glomerulonephritis induced in the pig by antibody to angiotensin-converting enzyme: considerations on its relevance to the pathogenesis of human idiopathic membranous glomerulonephritis. J Am Soc Nephrol 1999;10(10):2102-8.
  3. Maruyama S, Cantu E, 3rd, DeMartino C, Wang CY, Chen J, Al-Mohanna F, Nakeeb SM, D'Agati V, Pernis B, Galili U, Godman G, Stern DM, Andres G. Interaction of baboon anti-alpha-galactosyl antibody with pig tissues. Am J Pathol 1999;155(5):1635-49.
  4. Maruyama S, Cantu E, Pernis B, Galili U, Godman G, Stern DM, Andres G. Alpha-galactosyl antibody redistributes alpha-galactosyl at the surface of pig blood and endothelial cells. Transpl Immunol 1999;7(2):101-6.
  5. Schulman LL, O'Hair DP, Cantu E, McGregor C, Ginsberg ME. Salvage by volume reduction of chronic allograft rejection in emphysema. J Heart Lung Transplant 1999;18(2):107-12.
  6. Biancone L, Cantaluppi V, Segoloni G, Boccellino M, Del Sorbo L, Conaldi PG, Tjoelker LW, Maruyama S, Cantu E, Stern D, Andres G, Camussi G. Role of platelet-activating factor in functional alterations induced by xenoreactive antibodies in porcine endothelial cells. Transplantation 2000;70(8):1198-205.
  7. Maruyama S, Cantu E, 3rd, Galili U, D'Agati V, Godman G, Stern DM, Andres G. alpha-galactosyl epitopes on glycoproteins of porcine renal extracellular matrix. Kidney Int 2000;57(2):655-63.
  8. Lau CL, Cantu E, 3rd, Gonzalez-Stawinski GV, Holzknecht ZE, Nichols TC, Posther KE, Rayborn CA, Platt JL, Parker W, Davis RD. The role of antibodies and von Willebrand factor in discordant pulmonary xenotransplantation. Am J Transplant 2003;3(9):1065-75.
  9. Cantu E, 3rd, Appel JZ, 3rd, Hartwig MG, Woreta H, Green C, Messier R, Palmer SM, Davis RD, Jr. J. Maxwell Chamberlain Memorial Paper. Early fundoplication prevents chronic allograft dysfunction in patients with gastroesophageal reflux disease. Ann Thorac Surg 2004;78(4):1142-51; discussion -51.
  10. Cantu E, Davis RD. Lung Transplantation: Timing, Perioperative Considerations and Postoperative Outcome. Advances in Pulmonary Hypertension 2004;3(1):9-18.
  11. Cantu E, Parker W, Platt JL, Duane Davis R. Pulmonary xenotransplantation: rapidly progressing into the unknown. Am J Transplant 2004;4 Suppl 6:25-35.
  12. Hartwig MG, Appel JZ, 3rd, Cantu E, 3rd, Simsir S, Lin SS, Hsieh CC, Walczak R, Palmer SM, Davis RD, Jr. Improved results treating lung allograft failure with venovenous extracorporeal membrane oxygenation. Ann Thorac Surg 2005;80(5):1872-9; discussion 9-80.
  13. Hartwig MG, Patel V, Palmer SM, Cantu E, Appel JZ, Messier RH, Davis RD. Hepatitis B core antibody positive donors as a safe and effective therapeutic option to increase available organs for lung transplantation. Transplantation 2005;80(3):320-5.
  14. Lukes DJ, Cantu E, Gaca JG, Hallberg E, Karlsson-Parra A, Parker W, Olausson M, Davis RD. Oral feeding with pig peripheral lymphocytes decreases the xenogeneic delayed type hypersensitivity reaction in galactosyltransferase knockout mice. Transplant Proc 2005;37(8):3327-31.
  15. Radeva JI, Reed SD, Kalo Z, Kauf TL, Cantu E, 3rd, Cretin N, Schulman KA. Economic evaluation of everolimus vs. azathioprine at one year after de novo heart transplantation. Clin Transplant 2005;19(1):122-9.
  16. Appel JZ, 3rd, Hartwig MG, Cantu E, 3rd, Palmer SM, Reinsmoen NL, Davis RD. Role of flow cytometry to define unacceptable HLA antigens in lung transplant recipients with HLA-specific antibodies. Transplantation 2006;81(7):1049-57.
  17. Cantu E, Gaca JG, Palestrant D, Baig K, Lukes DJ, Gibson SE, Gonzalez-Stawinski GV, Olausson M, Parker W, Davis RD. Depletion of pulmonary intravascular macrophages prevents hyperacute pulmonary xenograft dysfunction. Transplantation 2006;81(8):1157-64.
  18. Appel JZ, 3rd, Lee SM, Hartwig MG, Li B, Hsieh CC, Cantu E, 3rd, Yoon Y, Lin SS, Parker W, Davis RD. Characterization of the innate immune response to chronic aspiration in a novel rodent model. Respir Res 2007;8:87.
  19. Cantu E, Balsara KR, Li B, Lau C, Gibson S, Wyse A, Baig K, Gaca J, Gonzalez-Stawinski GV, Nichols T, Parker W, Davis RD. Prolonged function of macrophage, von Willebrand factor-deficient porcine pulmonary xenografts. Am J Transplant 2007;7(1):66-75.
  20. Hartwig MG, Snyder LD, Appel JZ, 3rd, Cantu E, 3rd, Lin SS, Palmer SM, Davis RD. Rabbit anti-thymocyte globulin induction therapy does not prolong survival after lung transplantation. J Heart Lung Transplant 2008;27(5):547-53.
  21. de la Fuente SG, Safford SD, Cantu E, Ludwig KA. Spinal abscess presenting as the initial symptom of Crohn's disease. Int J Colorectal Dis 2009; May;24(5):601-2. doi: 10.1007/s00384-008-0599-5. Epub 2008 Oct 18. PubMed PMID: 18931849.
  22. Diamond Joshua M, Feng Rui, Meyer Nuala, Lederer David, Lee James C, Kawut Steven M, Ahya Vivek, Cantu Edward, Palmer Scott, Weinacker Ann, Bhorade Sangeeta, Lama Vibha, Orens Jonathan B, Sonett Joshua, Wille Keith, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim, Shah Ashish, Shah Pali D, Demissie Ejigayehu, Reynolds John, Belperio John, ilkes David, Ware Lorraine, Christie Jason D: PTX3 Polymorphisms Are Associated with Primary Graft Dysfunction after Lung Transplantation. The Journal of Heart and Lung Transplantation 30(4): S23, 2011, April. In press.
  23. Diamond JM, Meyer NJ, Feng R, Rushefski M,  Lederer DJ, Kawut SM, Lee JC, Cantu E, Shah R, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Weill D, Arcasoy S, Shah PD, Belperio JA, Wilkes D, Ware LB, Palmer SM and Christie JD for the Lung Transplant Outcomes Group.Variation in PTX3 is Associated With Primary Graft Dysfunction After Lung Transplantation. Am J Respir Crit Care Med. 2012 Sep 15;186(6):546-52.
  24. Shah RJ, Diamond JM, Lederer DJ, Arcasoy SM, Cantu E, Demissie EJ, Kawut SM, Kohl B, Lee JC, Sonett J, Christie JD, Ware, LB “Plasma Monocyte Chemotactic Protein-1 (MCP-1) levels at 24 hours are a biomarker of primary graft dysfunction following lung transplantation” Translational Res. 2012 Dec;160(6):435-42.
  25. Shah RJ, Bellamy SL, Lee JC, Cantu E, Diamond JM, Mangalmurti N, Kawut, SM, Ware LB, Christie JD "Early plasma soluble Receptor for Advanced Glycation End Product levels are associated with bronchiolitis obliterans syndrome"  American Journal of Transplantation  In press.
  26. Diamond JM, Porteous MK, Cantu E, Meyer NJ, Shah RJ, Lederer DJ, Kawut SM, Lee J, Bellamy S, Palmer SM, Lama VN, Bhorade S, Crespo M, Demissie E, Wille K, Orens J, Shah PD, Weinacker A, Weill D, Arcasoy S, Wilkes DS, Ware LB, and Christie JD for the Lung Transplant outcomes Group.  “Elevated Plasma Angiopoietin-2 Levels and Primary Graft Dysfunction after Lung Transplantation” PLoS ONE 2012;7(12):e51932.
  27. Cantu E, Lederer DJ, Meyer K, Milewski K, Suzuki Y, Shah RJ, Diamond JM, Meyer NJ, Tobias JW, Baldwin DA, Van Deerlin VM, Olthoff KM, Shaked A, Christie JD; for the CTOT Investigators. Gene set enrichment analysis identifies key innate pathways in primary graft dysfunction after lung transplantation. Am J Transplant. 2013 May 24. doi: 10.1111/ajt.12283.
  28. Farooki AM, Bazick-Cuschieri H, Gordon EK, Lee JC, Cantu E, Augoustides JG. CASE X-2013 Rescue Therapy With Early Extracorporeal Membrane Oxygenation for Primary Graft Dysfunction After Bilateral Lung Transplantation. J Cardiothorac Vasc Anesth. 2013 Aug 29. doi:pii: S1053-0770(13)00122-5.
    10.1053/j.jvca.2013.02.021. [Epub ahead of print] PubMed PMID: 23999325
  29. E Cantu, D. Lederer, K. Meyer, K. Milewski1, Y. Suzuki1, R.J. Shah, J.M. Diamond, N.J. Meyer, J.W. Tobias, D.A. Baldwin, V.M. Van Deerlin, K.M. Olthoff, A. Shaked, J.D. Christie: the CTOT Investigators. Gene set enrichment analysis identifies key innate immune pathways in primary graft dysfunction after lung transplantation. The Journal of Heart and Lung Transplantation. 2013 Jul;13(7):1898-904. doi: 10.1111/ajt.12283. Epub 2013 May 24.
    PubMed PMID: 23710539.
  30. Shah RJ, Diamond JM, Cantu E, Lee JC, Lederer DJ, Lama VN, Orens J, Weinacker A, Wilkes DS, Bhorade S, Wille KM, Ware LB, Palmer SM, Crespo M, Localio AR, Demissie E, Kawut SM, Bellamy SL, Christie JD. “Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation. Chest. 2013 Aug;144(2):616-22. doi: 10.1378/chest.12-1480. PubMed PMID: 23429890; PubMed Central PMCID: PMC3734891.
  31. Shah RJ, Bellamy SL, Lee JC, Cantu E, Diamond JM, Mangalmurti N, Kawut SM, Ware LB, Christie JD. Early plasma soluble receptor for advanced glycation end-product levels are associated with bronchiolitis obliterans syndrome. Am J Transplant. 2013 Mar;13(3):754-9. doi: 10.1111/ajt.12062. Epub 2013 Jan 17. PubMed PMID: 23331756; PubMed Central PMCID: PMC3582806.
  32. Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy SL, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade SM, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD; Lung Transplant Outcomes Group. Clinical risk factors for primary graft dysfunction after lung transplantation. Am J Respir Crit Care Med. 2013 Mar
    1;187(5):527-34. doi: 10.1164/rccm.201210-1865OC. Epub 2013 Jan 10. PubMed PMID: 23306540; PubMed Central PMCID: PMC3733407.
  33. Shah RJ, Wickersham N, Lederer DJ, Palmer SM, Cantu E, Diamond JM, Kawut, SM, Lama VN,
    Bhorade S, Crespo M, Demissie E, Sonnett J, Willie K, Orens J, Weinacker A, Shah P, Arcasoy S, Wilkes DS, Christie JD, Ware LB; “Preoperative plasma club (clara) cell secretory protein levels are associated with primary graft dysfunction after lung transplantation”. Lung Transplant Outcomes Group. Am J Transplant. 2014 Feb:14(2):446-52. Doi:10.1111/ajt.12541. Epub 2014 Jan 8. PMID:24400993 PubMed-in process.
  34. Diamond JM, Akimova T, Kazi A, Shah RJ, Cantu E, Feng R, Levine MH, Kawut SM, Meyer NJ, Lee JC, Hancock WW, Aplenc R, Ware LB, Palmer SM, Bhorade S, Lama VN, Weinacker A, Orens J, Wille K, Crespo M, Lederer DJ, Arcasoy S, Demissie E, Christie JD; “Genetic variation in the prostaglandin E2 pathway is associated with primary graft dysfunction” Am J  Respir Crit Care Med. 2014 Mar 1:189(5):567-75. doi:10.1164/rccm.201307-12830C. PubMed PMID:24467603.
  35. Cohen DG, Christie JD, Anderson BJ, Diamond JM, Judy RP, Shah RJ, Cantu E, Bellamy SL, Blumenthal NP, Demissie E, Hopkins RO, Mikkelsen ME: Cognitive function, mental health, and health-related quality of life after lung transplantation. Ann Am Thorac Soc. 2014 May; 11(4): 522-30. doi:10.1513/Annals ATS.201311-3880C.PMID:24605992. Pub-Med-in process
  36. Shah RJ, Emtiazjoo AM, Diamond JM, Smith PA, Roe DW, Wille KM, Orens JB, Ware LB, Weinacker A, Lama VN, Bhorade SM, Palmer SM, Crespo M, Lederer DJ, Cantu E, Eckert GJ, Christie JD, Wilkes DS. “Genetic variation in prostaglandin E2 pathway associated with primary graft dysfunction”. Amer J Respir Crit Care Med. 2014 Jun 15; 189(12):1564-7.doi:10.1164/rccm201312-2121LE. PMID:24930532. PubMed-in process
  37. Chaney J, Suzuki Y, Cantu E , van Berkel V. Lung donor selection criteria. J Thorac Dis 2014; 6(8):1032-1038. doi: 10.3978/j.issn.2072-1439.2014.03.24 Review. PMID: 25132970. PubMed.
  38. Shah RJ1, Emtiazjoo AM, Diamond JM, Smith PA, Roe DW, Wille KM, Orens JB, Ware LB, Weinacker A, Lama VN, Bhorade SM, Palmer SM, Crespo M, Lederer DJ, Cantu E, Eckert GJ, Christie JD, Wilkes DS. “Plasma complement levels are associated with primary graft dysfunction and mortality after lung transplantation.”Am J Respir Crit Care Med 2014 Jun 15; 189(12): 1564-7. Doi:10.1164/rccm.201312-2121LE. PMID: 24930532 Pub-Med-in process.
Abstracts
  1. O'Hair DP, Cantu E, Schulman LL, McGregor C, Simonelli P, Jellen P, Ginsberg ME. Lung Volume Reduction Surgery following Single Lung Transplantation for Emphysema. ISHLT 1996.
  2. O'Hair DP, Cantu E, Umana JP, McGregor C, Ginsberg ME, Schulman LL, Galantiwicz ME. Lung Transplantation Using Mycophenolate Mofetil. ISHLT 1996.
  3. Cantu E, Maruyama S, Al-Mohanna F, Nakeeb SM, Wang  CY, Godman G, Galili U, Stern DM, Andres G. Lesions Induced in Pig Lungs by Baboon Anti-alpha-Galactosyl Antibody. AHA 1998.
  4. Cantu E, Gaca JG, Lukes DJ , Palestrant D, Baig K, Gonzalez-Stawinski GV, Parker W, Davis RD. Depletion of Porcine Pulmonary Intravascular Macrophages Attenuates Hyperacute Pulmonary Xenograft Dysfunction. IXA 2003.
  5. Cantu E, Gaca JG, Lukes DJ , Palestrant D, Baig K, Gonzalez-Stawinski GV, Parker W, Davis RD. Passenger Pulmonary Macrophages Play a Key Role in the Coagulopathy and Endothelial Activation Associated with Pulmonary Xenograft Dysfunction. IXA 2003.
  6. Cantu E, Gibson S, Wyse A, Lau CL, Gaca JG, Gonzalez-Stawinski GV, Baig K, Nichols T, Parker W, Davis RD. Role of porcine von Willebrand factor in Pulmonary Xenograft Injury. IXA 2003.
  7. Cantu E, Appel JZ, Hartwig MG, Palmer S, Messier R, Davis RD. Early Fundoplication Prevents Chronic Allograft Dysfunction In Patients With Gastroesophageal Reflux Disease (GERD). STS  2003 (J. Maxwell Chamberlain Award).
  8. Lukes DJ, Cantu E, Gaca JG, Hallberg E, Karlsson-Parra A, Parker W, Olausson M, Davis RD.Oral Feeding With Pig Peripheral Lymphocytes (pPBL) Decreases The Xenogeneic DTH Reaction In Galactosyltransferase Knockout Mice. STA 2003.
  9. Appel JZ, Cantu E, Hartwig MG, Reinsmoen NL, Palmer SM and Davis RD. Role of Flow Cytometry to Exclude Unacceptable HLA Antigens in Lung Transplant Recipients with Anti-HLA Antibodies. ISHLT 2004.
  10. Hartwig MG, Cantu E, Appel JZ, Woreta H, Palmer SM and Davis RD. Non- Alloimmune Injury Mediated by Gastroesophageal Reflux Precipitates Alloimmune Injury in Lung Transplant Patients. ISHLT 2004.
  11. Hartwig MG, Kadakia A, Cantu E, Appel JZ, Davis RD, Palmer SM. Non-Specific Bronchial Hyperreactivity After Lung Transplant is not Related to Gastroesophageal Reflux or Predictive of Clinical Outcomes. ATS 2004.
  12. Hartwig MG, Appel JZ, Cantu E, Davis RD. Early reflux monitoring following lung transplantation may underestimate the incidence of gastroesophageal reflux. ATC 2004.
  13. Appel JZ, Burgess BO, Herczyk WF, Cantu E, Hartwig MG, Palmer SM, Davis RD, Reinsmoen NL. Perioperative desensitization therapy decreases acute rejection in sensitized lung transplant recipients. ASHI 2004.
  14. Appel JZ, Burnette A, Mohler K, Li B, Hartwig M, Cantu E, Palmer S, Parker W, Reinsmoen N, Davis D. Role of cellular immunity in GERD-associated bronchiolitis obliterans syndrome. ACS 2004.
  15. Cantu E, Gibson S, Wyse A, Lau C, Gaca J, Gonzalez-Stawinskil GV, Baig K, Nichols T, Parker W, Davis RD. Porcine von Willebrand factor antigen deficiency with pulmonary intravascular macrophage depletion abrogates hyperacute pulmonary xenograft dysfunction. ATC 2004.
  16. Bush EL, Appel JZ, Li B, Balsara KR, Hartwig M, Cantu E, Parker W, Davis RD, Lin SS. Chronic aspiration in lung allotransplantation induces a donor-specific hyperimmune state. ISHLT 2007.
  17. Bush EL, Balsara KR, Hartwig M, Pbillips-Bute BG, Shaw A, Cantu E, Appel JZ, Davis RD, Welsby IJ, Lin SS. Perioperative predictors of renal failure following off-pump primary double lung transplantation. ISHLT 2007.
  18. Bush EL, Balsara KR, Hartwig MG, Appel JZ, Cantu E, Simsir SA, Parker WR, Palmer SM, Lin SS, Davis RD. Effectiveness of non-primary single lung transplants for patients with COPD and bronchiolitis obliterans syndrome (BOS) following initial lung transplant. ATC 2007.
  19. Balsara KR, Cantu E, Bush EL, Appel JZ, Hartwig MG, Lin SS, Davis RD. Early fundoplication reduces the incidence of chronic allograft drysfunction in patients with gastroesophageal reflux disease. ISHLT 2008.
  20. Shah RJ, Diamond JM, Kawut S, Cantu E, Wickersham N, Ware LB, Christie JD. Plasma RAGE levels measured 24 hours after lung transplantation are associated with bronchiolitis obliterans syndrome (BOS). ISHLT 2012.
  21. Diamond JM, Feng R, Meyer NJ, Shah R, Kawut SM, Lederer DJ, Lee JC, Ahya V, Cantu E, Weinacker A, Bhorade S, Lama VN, Orens JB, Sonett J, Willie KM, Crespo M, Weill D, Kohl B, Arcasoy SM, Shah AS, Shah PD, Demissie E, Reynolds JM, Belperio JA, Wilkes D, Ware LB, Palmer SM, Christie JD. Functional TLR4 polymorphisms are associated with lower risk of primary graft dysfunction (PGD) after lung transplantation. ISHLT 2012.
  22. Cantu E, Erhunmwunsee L, Feng R, Meyer NJ, Diamond JM, Shah RJ, Rao S, Lin SS, Davis RD, Christi JD. Paired donor lung expression suggest key effectors in primary graft dysfunction. ISHLT 2012.
  23. Diamond JM, Meyer NJ, Feng R, Rushefski M,  Lederer DJ, Kawut SM, Lee JC, Cantu E, Shah R, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Weill D, Arcasoy S, Shah PD, Belperio JA, Wilkes D, Ware LB, Palmer SM and Christie JD for the Lung Transplant Outcomes Group.Variation in PTX3 is Associated With Primary Graft Dysfunction After Lung Transplantation. American Journal of Respiratory and Critical Care Medicine. In press.
  24. Diamond JM, Meyer NJ, Feng R, Rushefski M,  Lederer DJ, Kawut SM, Lee JC, Cantu E, Shah R, Lama VN, Bhorade S, Crespo M, Demissie E, Sonett J, Wille K, Orens J, Weinacker A, Weill D, Arcasoy S, Shah PD, Belperio JA, Wilkes D, Ware LB, Palmer SM and Christie JD for the Lung Transplant Outcomes Group: Variation in PTX3 is Associated With Primary Graft Dysfunction After Lung Transplantation. American Journal of Respiratory and Critical Care Medicine In Press.
  25. Diamond Joshua M, Feng Rui, Meyer Nuala, Lederer David, Lee James C, Kawut Steven M, Ahya Vivek, Cantu Edward, Palmer Scott, Weinacker Ann, Bhorade Sangeeta, Lama Vibha, Orens Jonathan B, Sonett Joshua, Wille Keith, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim, Shah Ashish, Shah Pali D, Demissie Ejigayehu, Reynolds John, Belperio John, Wilkes David, Ware Lorraine, Christie Jason D: PTX3 Polymorphisms Are Associated with Primary Graft Dysfunction after Lung Transplantation. The Journal of Heart and Lung Transplantation 30(4): S23, April 2011 Notes: International Society for Heart and Lung Transplantation 2011
  26. Diamond Joshua M, Lederer David, Kawut Steven M, Lee James C, Cantu Edward, Ahya Vivek, Palmer Scott, Weinacker Ann, Bhorade Sangeeta, Lama Vibha, Orens Jonathan B, Sonett Joshua, Wille Keith, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim, Shah Ashish, Shah Pali D, Demissie Ejigayehu, Reynolds John, Belperio John, Wilkes David, Ware Lorraine, Christie Jason D: Elevated PTX3 Concentration Is Associated with Primary Graft Dysfunction after Lung Transplantation in Patients with Idiopathic Pulmonary Fibrosis The Journal of Heart and Lung Transplantation 30(4): S23-S24, April 2011 Notes: International Society for Heart and Lung Transplantation 2011
  27. Diamond Joshua M, Feng Rui, Meyer Nuala J, Kawut Steven M, Lee James C, Ahya Vivek, Cantu Edward, Ware Lorraine, Palmer Scott M, Bhorade Sangeeta, Lama Vibha N, Weinacker Ann, Orens Jonathan B, Sonett Joshua, Wille Keith M, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim M, Shah Ashish S, Shah Pali D, Demissie Ejigayehu, Reynolds John M, Belperio John A, Lederer David J, Christie Jason D: Genetic Variation In Prostaglandin E2 Family Members Is Associated With The Development Of Primary Graft Dysfunction After Lung Transplantation  American Journal of Respiratory and Critical Care Medicine Page: A4014, May 2011 Notes: American Thoracic Society 2011.
  28. Diamond Joshua M, Feng Rui, Meyer Nuala J, Kawut Steven M, Lee James C, Ahya Vivek, Cantu Edward, Ware Lorraine, Palmer Scott M, Bhorade Sangeeta, Lama Vibha N, Weinacker Ann, Orens Jonathan B, Sonett Joshua, Wille Keith M, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim M, Shah Ashish S, Shah Pali D, Demissie Ejigayehu, Reynolds John M, Belperio John A, Lederer David J, Christie Jason D: Genetic Variation In Prostaglandin E2 Family Members Is Associated With The Development Of Primary Graft Dysfunction After Lung Transplantation. University of Pennsylvania Department of Medicine Research Day June 2011.
  29. Diamond Joshua M, Feng Rui, Meyer Nuala J, Kawut Steven M, Lee James C, Ahya Vivek, Cantu Edward, Ware Lorraine, Palmer Scott M, Bhorade Sangeeta, Lama Vibha N, Weinacker Ann, Orens Jonathan B, Sonett Joshua, Wille Keith M, Crespo Maria, Weill David, Kohl Benjamin, Deutschman Clifford, Arcasoy Selim M, Shah Ashish S, Shah Pali D, Demissie Ejigayehu, Reynolds John M, Belperio John A, Lederer David J, Christie Jason D: Genetic Variation in Prostaglandin E2 Family Members is Associated with the Development of Primary Graft Dysfunction. NHLBI Symposium on Gene Discovery and Clinical Applications for Cardiovascular, Lung, and Blood Diseases  September 2011.
  30. Diamond Joshua M, Feng Rui, Meyer Nuala J, Shah Rupal J, Kawut Steven M, Lederer David J, Lee James C, Ahya Vivek, Cantu Edward, Weinacker Ann, Bhorade Sangeeta, Lama Vibha N, Orens Jonathan B, Sonett Joshua, Wille Keith M, Crespo Maria, Weill David, Kohl Benjamin, Arcasoy Selim M, Shah Ashish S, Shah Pali D, Demissie Ejigayehu, Reynolds John M, Belperio John A, Wilkes David, Ware Lorraine B, Palmer Scott M, Christie Jason D: Functional TLR4 Polymorphisms Are Associated with Lower Risk of Primary Graft Dysfunction (PGD) after Lung Transplantation The Journal of Heart and Lung Transplantation 31(4): S76, April 2012 Notes: International Society of Heart and Lung Transplantation 2012
  31. Porteous Mary, Diamond Joshua M, Meyer Nuala J, Lederer David J, Kawut Steven M, Lee James, Cantu Edward, Palmer Scott M, Weinacker Ann, Bhorade Sangeeta, Lama Vibha N, Orens Jonathan, Sonett Joshua, Crespo Maria M, Wille Keith M, Weill David, Demissie Ejigayehu, Reynolds John M, Belperio John A, Wilkes David S, Ware Lorraine B, Christie Jason D : Association Of Angiopoietin-2 Plasma Levels And Development Of Primary Graft Dysfunction Following Lung Transplantation  American Journal of Respiratory and Critical Care Medicine Page: A3762, May 2012 Notes: American Thoracic Society 2012.
  32. E Cantu, L Erhunmwunsee, R Feng, N.J. Meyer, J.M. Diamond, R.J. Shah, S Rao, S.S. Lin, R.D. Davis, J.D. Christie: Paired Donor Lung Expression Suggest Key Effectors in Primary Graft Dysfunction, The Journal of Heart and Lung Transplantation ISHLT 2012.
  33. Shah RJ, Diamond JM, Kawut S, Cantu E, Wickersham N, Ware LB, Christie JD. Plasma RAGE levels measured 24 hours after lung transplantation are associated with bronchiolitis obliterans syndrome (BOS). ISHLT 2012.
  34. Diamond JM, Feng R, Meyer NJ, Shah R, Kawut SM, Lederer DJ, Lee JC, Ahya V, Cantu E, Weinacker A, Bhorade S, Lama VN, Orens JB, Sonett J, Willie KM, Crespo M, Weill D, Kohl B, Arcasoy SM, Shah AS, Shah PD, Demissie E, Reynolds JM, Belperio JA, Wilkes D, Ware LB, Palmer SM, Christie JD. Functional TLR4 polymorphisms are associated with lower risk of primary graft dysfunction (PGD) after lung transplantation. ISHLT 2012.
  35. Cantu E, Erhunmwunsee L, Feng R, Meyer NJ, Diamond JM, Shah RJ, Rao S, Lin SS, Davis RD, Christi JD. Paired donor lung expression suggest key effectors in primary graft dysfunction. ISHLT 2012.
  36. Shah RJ, Bellamy SL, Lee JC, Cantu E, Diamond JM, Mangalmurti N, Kawut SM, Ware LB, Christie JD: Early Plasma Soluble Receptor for Advanced Glycation End-Product Levels Are Associated With Bronchiolitis Obliterans Syndrome. Am J Transplant. 2013 Jan 17.
  37. Shah, Rupal; Diamond, Joshua; Cantu, Edward; Lee, James; Lederer, David; Lama, Vibha; Orens, Jonathan; Weinacker, Ann; Wilkes, David; Bhorade, Sangeeta; Wille, Keith; Ware, Lorraine; Palmer, Scott; Crespo, Maria M; Localio, A. Russell; Demissie, EJ; Kawut, Steven; Bellamy, Scarlett; Christie, Jason: "Latent class analysis identifies distinct phenotypes of primary graft dysfunction after lung transplantation." CHEST.
  38. Edward Cantu, Yoshikazu Suzuki, Joshua M. Diamond, Rupal Shah, Nuala J. Meyer, David J. Lederer, Steven M. Kawut, James Lee, Scott M. Palmer, Vibha N. Lama, Sangeeta Bhorade8, Maria Crespo, Ejigayehu Demissie, Keith Wille, Jonathan Orens, Pali D. Shah, Ann Weinacker, David Weill, Selim Arcasoy, David Wilkes, David Roe, Lorraine B. Ware, Clifford S. Deutschman, Rui Feng, Jason D. Christie: the Lung Transplant Outcomes Group. Protein quantitative trait loci analysis identifies genetic variation in the innate immune regulator TOLLIP in post lung transplant primary graft dysfunction risk. The Journal of Heart and Lung Transplantation. ISHLT 2013.
  39. E. Cantu, D. Lederer, K. Meyer, K. Milewski1, Y. Suzuki1, R.J. Shah, J.M. Diamond, N.J. Meyer, J.W. Tobias, D.A. Baldwin, V.M. Van Deerlin, K.M. Olthoff, A. Shaked, J.D. Christie: the CTOT Investigators. Gene set enrichment analysis identifies key innate immune pathways in primary graft dysfunction after lung transplantation. The Journal of Heart and Lung Transplantation.  ISHLT 2013.
  40. P.G. Sanchez, R.D. Davis, F. D’ovidio, M.J. Weyan, P.C. Camp, E. Cantu, B.P. Griffith: Cardiac Surgery, University of Maryland, Baltimore, MD; Cardiac Surgery, Duke University, Durham, NC; Surgery, Columbia University, New York, NY; Surgery, University of Colorado, Aurora, CO; Thoracic Surgery, Brigham and Women’s Hospital, Boston, MA; Cardiac Surgery, University of Pennsylvania, Philadelphia, PA. The Journal of Heart and Lung Transplantation. ISHLT 2013.
  41. Diamond JM, Lee JC, Kawut SM, Shah RJ, Localio AR, Bellamy S, Lederer DJ, Cantu E, Kohl BA, Lama VN, Bhorade S, Crespo M, Demissie E, Sonnett J, Wille K, Orens J, Shah AS, Weinacker A, Arcasoy S, Shah PD, Wilkes DS, Ware LB, Palmer SM, Christie JD; for the Lung Transplant Outcomes Group. Clinical Risk Factors for Primary Graft Dysfunction after Lung Transplantation. The Journal of Heart and Lung Transplantation. ISHLT 2013.             
Editorship
  1. Cantu E, Turek J. Editor. Case-Based Review of Cardiothoracic Surgery. May 4, 2013. 1st ed. Fox and Locke Publishing.

Book Chapters

  1. Cantu E, D’Amico TA. Thoracoscopic Pulmonary Resection. Pappas TN, Pryor AD, Harnisch MP, eds. Atlas of laparoscopic surgery. 3rd ed. Philadelphia: Current Medicine; 2007.
  2. Cantu E, Milano CA, Smith PK. Critical Care for the Adult Cardiac Patient. In Sellke FW, Del Nido PJ, Swanson SJ, Sabiston DC, Spencer FC, eds. Sabiston & Spencer: Surgery of the Chest. 7th ed. Philadelphia, Pa.: Elsevier Saunders; 2009.
  3. Cantu E, Zaas DW. Organ Donor Management and Procurement. In Klein AA, Lewis C, Madsen J, eds. Organ Transplantation: A Clinical Guide. 1st ed. United Kingdom:  Cambridge University Press; 2011.
  4. Cantu E. Aortic Stenosis. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.
  5. Cantu E. Acute Pulmonary Embolus. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.
  6. Cantu E. Chronic Pulmonary Embolus. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.
  7. Cantu E. Constrictive Pericarditis. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.
  8. Cantu E. Cardiac Tumor. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.
  9. Cantu E. Cardiac Ischemia. In Cantu E, Turek J, eds. Case-Based Review of Cardiothoracic Surgery. 1st ed. Fox and Locke Publishing. May 2013.          
 
Awards
2014 NIH LRP Award
 
2014 Thoracic Surgery Foundation for Research and Education Award
 
2013 Section Editor: Current Opinion in Organ Transplantation
 
2012 Harold Amos Medical Faculty Development Program Award
 
2011 Philadelphia Antiques Show and Board of Women Visitors Grant for most promising Research
 
2011 McCabe Award
 
2007 American Society of Transplant Surgeons Thoracic Award
 
2007 NIH LRP Award
 
2003 STS J. Maxwell Chamberlain Award
 
2002 - 2004 Ruth L. Kirschstein National Research Service Award
 
2000 Samuel W. Rover and Lewis Rover Award in Physiology and Cellular Biophysics
 
2000 Aura E. Severinghaus Scholar
 
1997 - 1998 NIH RO1Supplemental Grant
 
1996 - 1997 American Heart Association Research Grant
 
1994 Graduation cum laude, Harvard University

Dr. Edward Cantu

 
footer Terms of Use Legal Disclaimer Site Map Contact Us Financial Assistance About Penn Medicine Privacy Statement
penn medicine