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Nimesh D. Desai, M.D.
Cardiovascular Surgery

 
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Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
6th Floor Silverstein Pavilion
Philadelphia, PA 19104
Administrative Assistant: Heather Verdi
Administrative Telephone: 215-615-0343

Clinical Office:
Pennsylvania Hospital
700 Spruce Street, Suite 305
Philadelphia, PA 19106
Telephone: 215-829-8713
Fax: 215-829-8780

Perelman Center for Advanced Medicine
Penn Heart and Vascular Center

East Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Telephone: 215-615-0343

Contact Information (internal use only)

nimesh.desai@uphs.upenn.edu

 

Dr. Desai received his medical degree from the Schulich School of Medicine at the University of Western Ontario and his doctorate of philosophy in clinical epidemiology from the University of Toronto. He completed an integrated cardiac
surgery residency at the University of Toronto and is a Fellow of the Royal College of Surgeons of Canada. He most recently completed an advanced surgical fellowship at Penn Medicine with an emphasis on aortic and endovascular surgery.

Dr. Desai’s research interests include organizing large multi-center clinical trials to assess new cardiovascular technologies and health process evaluations to improve quality of care for cardiac patients. Dr. Desai’s clinical focus is on advanced aortic surgery, both endovascular and open, percutaneous aortic valve replacement, complex valve surgery, multiple arterial grafting and hybrid surgical approaches to atrial fibrillation.

 
Faculty Appointments
2009 - present Assistant Professor of Surgery at HUP, PPMC & PAH
Perelman School of Medicine
Philadelphia, Pennsylvania
 
Hospital and Administrative Appointments
2009 - present Attending Surgeon
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2009 - present Active Surgeon
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania
 
2009 - present Active Surgeon
Pennsylvania Hospital
Philadelphia, Pennsylvania
 
Other Appointments
2004 - present Council Member
Gerson Lehrman Group Healthcare Council
New York, New York
 
Education/Training
1992 - 1996 B.Sc. University of Ottawa
(Biochemistry, Summa Cum Laude)
 
1996 - 2000 M.D. University of Western Ontario
 
2004 - 2008 Ph.D. University of Toronto
(Clinical Epidemiology)
 
Postgraduate Training and Fellowship Appointments
July 2000 -
June 2002
Core Junior Surgery Residency (Cardiac)
University of Toronto, Toronto, Ontario, Canada
 
July 2002 -
June 2005
Research Fellowship/PhD, University of Toronto
Toronto, Ontario, Canada
 
July 2005 -
Dec. 2005
Senior Thoracic Surgery Resident
Trillium Hospital, Mississauga, Ontario, Canada
 
Jan. 2006 -
June 2006
Senior Vascular Surgery Resident
Toronto General Hospital, Toronto, Ontario, Canada
 
July 2006 -
Dec. 2006
Senior Cardiac Surgery Resident
Sunnybrook Hospital, Toronto, Ontario, Canada
 
Jan. 2007 -
July 2007
Chief Cardiac Surgery Resident, St. Michael’s Hospital
Toronto, Ontario, Canada
 
July 2007 -
Dec. 2007
Chief Congenital Cardiac Resident
Hospital for Sick Children, Toronto, Ontario, Canada
 
Jan. 2008 -
July 2008
Chief Cardiac Surgery Resident
Toronto General Hospital, Toronto, Ontario, Canada
 
July 2008 -
June 2009
Advance Aortic Surgery Fellow
University of Pennsylvania Medical Center
Philadelphia, Pennsylvania
 
Memberships/Societies
 
 
 
 
 
 
 
 
Research
 
Research Publications, peer reviewed (print or other media)
  1. Del Rizzo DF, Boyd WD, Novick RJ, McKenzie FN, Desai ND, Menkis AH: Safety and cost-effectiveness of MIDCABG in high-risk CABG patients. Annals of Thoracic Surgery 66(3): 1002-1007, September 1998.
  2. Boyd WD, Desai ND, Del Rizzo DF, Novick RJ, McKenzie FN, Menkis AH: Off-pump surgery decreases postoperative complications and resource utilization in the elderly. Annals of Thoracic Surgery 68(4): 1490-1493, October 1999.
  3. Boyd WD, Desai ND, Novick RJ, McKenzie FN, Del Rizzo DF, Menkis AH: Use of cardio-pulmonary bypass in high-risk patients is a predictor of adverse outcome. Seminars in Cardiothoracic & Vascular Anesthesia 4(2): 86-91, July 2000.
  4. Boyd WD, Desai ND, Kiaii B, Rayman R, Menkis AH, McKenzie FN, Novick RJ: A comparison of robot-assisted versus manually constructed endoscopic coronary anastomosis. Annals of Thoracic Surgery 70(3): 839-843, September 2000.
  5. Boyd WD, Rayman R, Desai ND, Menkis AH, Dobkowski W, Ganapathy S, Kiaii B, Jablonsky G, McKenzie FN, Novick RJ: Closed-chest coronary artery bypass grafting on the beating heart with the use of a computer-enhanced surgical robotic system. Journal of Thoracic & Cardiovascular Surgery 120(4): 807-809, October 2000.
  6. Abrahamov D, Erez E, Tamariz M, Dagan O, Pearl E, Abrahamov Y, Gendel B, Desai N, Kats J, Vidne B, Barak V: Plasma vascular endothelial growth factor level is a predictor of the severity of postoperative capillary leak syndrome in neonates undergoing cardiopulmonary bypass. Pediatric Surgery International 18(1): 54-59, January 2002.
  7. Cohen J, Butany J, Leask RL, Desai ND, Lenkie S, Feindel CM: Chronic aortic dissection: 27 years after aortic valve replacement. Canadian Journal of Cardiology 18(4): 437-438, April 2002.
  8. Desai ND, Butany J: Cardiac tumors. Geriatrics and Aging 5(3): 22-27, 2002.
  9. Mallidi HR, Pelletier MP, Lamb J, Desai N, Sever J, Christakis GT, Cohen G, Goldman BS, Fremes SE: Late outcomes in patients with uncorrected mild to moderate mitral regurgitation at the time of isolated coronary artery bypass grafting. Journal of Thoracic & Cardiovascular Surgery 127(3): 636-644, March 2004.
  10. Desai ND, Pelletier MP, Mallidi HR, Christakis GT, Cohen GN, Fremes SE, Goldman BS: Why is off-pump coronary surgery uncommon in Canada? Results of a population-based survey of Canadian heart surgeons. Circulation 110(11 Suppl 1): II7-12, September 2004.
  11. Desai ND, Cohen EA, Naylor CD, Fremes SE: Radial Artery Patency Study Investigators. A randomized comparison of radial-artery and saphenous-vein coronary bypass grafts. New England Journal of Medicine 351(22): 2302-2309, November 2004.
  12. Desai ND, Merin O, Cohen GN, Herman J, Mobilos S, Sever JY, Fremes SE, Goldman BS, Christakis GT: Long-term results of aortic valve replacement with the St. Jude Toronto stentless porcine valve. Annals of Thoracic Surgery 78(6): 2076-2083, December 2004.
  13. Desai ND, Miwa S, Kodama D, Cohen G, Christakis GT, Goldman BS, Baerlocher MO, Pelletier MP, Fremes SE: Improving the quality of coronary bypass surgery with intraoperative angiography: Validation of a new technique. Journal of the American College of Cardiology 46(8): 1521-1525, October 2005.
  14. Desai ND: Invited Commentary. Annals of Thoracic Surgery 80(6): 2192-3, December 2005. PMCID: 16305869.
  15. Miwa S, Desai N, Koyama T, Chan E, Cohen EA, Fremes SE: Radial Artery Patency Study Investigators. Radial artery angiographic string sign: Clinical consequences and the role of pharmacologic therapy. Annals of Thoracic Surgery 81(1): 112-119, January 2006.
  16. Desai ND, Fremes SE: Efficacy and safety of edifoligide: Letter to the editor. Journal of American Medical Association 295(13): 1514-5, April 2006. PMCID: 16595752.
  17. Desai ND, Miwa S, Kodama D, Koyama T, Cohen G, Pelletier MP, Cohen EA, Christakis GT, Goldman BS, Fremes SE: A randomized comparison of intraoperative indocyanine green angiography and transit-time flow measurement to detect technical errors in coronary bypass grafts. Journal of Thoracic & Cardiovascular Surgery 132(3): 585-594, September 2006.
  18. Butany J, Leask RL, Desai ND, Jegatheeswaran A, Silversides C, Scully HE, Feindel C: Pathologic analysis of 19 heart valves with silver-coated sewing rings. Journal of Cardiac Surgery 21(6): 530-538, November/December 2006.
  19. Desai ND, Naylor CD, Kiss A, Cohen EA, Feder-Elituv R, Miwa S, Radhakrishnan S, Dubbin J, Schwartz L, Fremes SE: Radial Artery Patency Study Investigators. Impact of patient and target-vessel characteristics on arterial and venous bypass graft patency: Insight from a randomized trial. Circulation 115(6): 684-691, February 2007.
  20. Desai ND: Pitfalls assessing the rold of drug-eluting stents in multivessel coronary disease. Annals of Thoracic Surgery 85(1): 25-7, January 2008. PMCID: 18154771.
  21. Desai ND, Moussa F, Singh SK, Chu P, Fremes SE: Intraoperative fluorescence angio-graphy to determine the extent of injury after penetrating cardiac trauma. Journal of Thoracic & Cardiovascular Surgery 136(1): 218-219, July 2008.
  22. Desai ND, Moussa F, Singh SK, Chu P, Fremes SE: Intraoperative fluorescence angiography to determine the extent of injury after penetrating cardiac trauma. Journal of Thoracic and Cardiovascular Surgery 136(1): 218-9, July 2008. PMCID: 18603081.
  23. MacIver J, Rao V, Delgado DH, Desai N, Ivanov J, Abbey S, Ross HJ: Choices: A study of preferences for end-of-life treatments in patients with advanced heart failure. Journal of Heart & Lung Transplantation 27(9): 1002-1007, September 2008.
  24. Singh SK, Desai ND, Petroff SD, Deb S, Cohen EA, Radhakrishnan S, Schwartz L, Dubbin J, Fremes SE: Radial Artery Patency Study Investigators. The impact of diabetic status on coronary artery bypass graft patency: Insights from the radial artery patency study. Circulation 118(14 Suppl): S222-225, September 2008.
  25. Desai ND: Comment on Levine et al. "Rescue percutaneous coronary intervention for graft failure immediately after coronary artery bypass grafting: case report and review of literature." Journal of Cardiac Surgery 23(6): 713-715, Nov-Dec 2008. PMCID: 19016997.
  26. Desai ND, Szeto WY: Complex aortic arch aneurysm and dissections: hybrid techniques for surgical and endovascular therapy. Current Opinion in Cardiology 24(6): 521-527, November 2009. PMCID: 19809310.
  27. Desai ND, Christakis GT, Cohen GN, Sever JY, Fremes SE, Goldman BS: Durability of stent-less aortic bioprostheses in the subcoronary position: A comparison with stented porcine and pericardial bioprostheses. Annals of Thoracic Surgery 2009.
  28. Desai ND, Pochettino A: Distal aortic remodeling using endovascular repair in acute DeBakey I aortic dissection. Seminars in Thoracic and Cardiovascular Surgery 21(4): 387-392, Winter 2009. PMCID: 20226353.
  29. Singh SK, Desai ND, Chikazawa G, Tsuneyoshi H, Vincent J, Zagorski BM, Pen V, Moussa F, Cohen GN, Christakis GT, Fremes SE: The Graft Imaging to Improve Patency (GRIIP) clinical trial results. The Journal of Thoracic and Cardiovascular Surgery 139(2), February 2010. PMCID: 20006356.
  30. Szeto WY, Moser WG, Desai ND, Milewski RK, Cheung AT, Pochettino A, Bavaria JE: Transapical deployment of endovascular thoracic aortic stent graft for an ascending aortic psuedoaneurysm. The Annals of Thoracic Surgery 89(2): 616-618, February 2010. PMCID: 20103359.
  31. Milewski RK, Pacini D, Moser GW, Moeller P, Cowie D, Szeto WY, Woo YJ, Desai N, Di Marco L, Pochettino A, Di Bartolomeo R, Bavaria JE: Retrograde and antegrade cerebral perfusion: results in short elective arch reconstructive times. Annals of Thoracic Surgery 89(5): 1448-1457, May 2010. PMCID: 20417760.
  32. Andritsos M, Desai ND, Grewal A, Augoustides JG: Innovations in aortic disease management: the descending aorta. Journal of Cardiothoracic and Vascular Anesthesia 24(3): 253-529, June 2010. PMCID: 20399116.
  33. Augoustides J, Szeto WY, Desai ND, Pochettino A, Cheung, AT, Savino JS, Bavaria, JE: Classification of acute type a dissection: focus on clinical presentation and extent. European Journal of Cardiothoracic Surgery July 2010. PMCID: 20615719
Research Publications, peer-reviewed reviews
  1. Fazel S, Angoulvant D, Desai N, Yang S, Weisel RD, Li RK: Cardiac restoration: Frontier or fantasy? Canadian Journal of Cardiology 21(4): 355-359, March 2005.
  2. Desai ND, Fremes SE: Radial artery conduit for coronary revascularization: As good as an internal thoracic artery? Current Opinion in Cardiology 22(6): 534-540, November 2007.
 
Publications
 
Abstracts
  1. Deb S, Desai ND, Fremes SE: Peripheral neurological complications following radial artery harvesting in coronary artery bypass surgery: Analysis from a randomized controlled clinical trial. Canadian Cardiovascular Congress, Vancouver, British Columbia October 2006.
  2. Desai ND, Christakis GT, Cohen GN, Sever JY, Deb S, Tarulli M, Fremes SE, Goldman BS: Durability of stentless aortic bioprostheses in the subcoronary position: A comparison with stented porcine and pericardial bioprostheses. Canadian Cardiovascular Congress, Vancouver, British Columbia October 2006.
  3. Desai ND, Christakis GT, Cohen GN, Tarulli M, Deb S, Sever JY, Fremes SE, Goldman BS: Impact of small aortic prosthesis on early and late mortality after aortic valve replace-ment. Canadian Cardiovascular Congress, Vancouver, British Columbia October 2006.
  4. Gupta M, Braga M, Gillett J, Desai N, Verma S: LDL response to statins does not differ between South Asians and white Caucasians. Canadian Cardiovascular Congress, Vancouver, British Columbia October 2006.
  5. Desai ND, Christakis GT, Cohen GN, Sever JY, Fremes SE, Goldman BS: Durability of stentless aortic bioprostheses in the subcoronary position: A comparison with stented porcine and pericardial bioprostheses. Society of Thoracic Surgeons Meeting, San Diego, CA January 2007.
  6. Desai ND, Singh SK, Lagopoulos ME. Christakis GT, Nesher N, Cohen GN, Fremes SE, Goldman BS: Intraoperative graft assessment reduces myocardial injury after coronary bypass surgery. Society of Thoracic Surgeons Meeting, San Diego, CA January 2007.
  7. Desai ND, Kapila V, Pelletier MP, Cohen G, Goldman BS, Christakis GT, Fremes SE: Platelet transfusions are a potential cause of mortality and morbidity after coronary artery bypass grafting. American College of Cardiology, New Orleans, LA March 2007.
  8. Desai ND, Christakis GT, Cohen GN, Sever JY, Fremes SE, Goldman BS: Impact of small aortic prosthesis on early and late mortality after aortic valve replacement. Society for Heart Valve Disease Meeting, New York, NY June 2007.
  9. Desai ND, Christakis GT, Cohen GN, Goldman BS, Fremes SE: Multiple Arterial Grafting in the Setting of Acute Myocardial Infarction. Canadian Cardiovascular Society, Quebec City, Quebec 2007.
  10. Desai ND, Christakis GT, Cohen GN, Goldman BS, Fremes SE: The role of multiple arterial grafting in the setting of acute myocardial infarction. American Heart Association Scientific Sessions 2007.
  11. Desai ND, Singh SK, Lagopoulos ME. Christakis GT, Nesher N, Cohen GN, Fremes SE, Goldman BS: Intraoperative graft assessment reduces myocardial injury after coronary bypass surgery. Canadian Cardiovascular Society, Quebec City, Quebec 2007.
  12. MacIver J, Desai ND, Delgado D, Rao V, Abbey S, Ross HJ: Congestive heart failure: Offering individualized choice evaluation study. International Society for Heart Lung Disease Meeting, San Francisco, CA 2007.
  13. Desai ND, Rajan D, Tan KT, Rubin BB: Emergent thoracic endografting in a peripartum Marfan's patient. American Association of Thoracic Surgery Aortic Symposium 2008.
  14. Desai ND, Gleason TG, Coselli JS, David TE, Smith III JM, Bavaria, JE: Mid-term results of the st. jude medical toronto root bioprosthesis. Society of Heart Valve Disease 2009.
  15. Desai ND, Szeto W, Zeeshan A, Brown D, Moeller P, Pochettino A, Bavaria JE: Durability of porcine bioroots in younger patients with aortic root pathology: A propensity matched comparison with composite mechanical roots. Society of Heart Valve Disease 2009.
  16. Desai ND, Szeto WY, Zeeshan A, Brown D, Pochettino A, McCarthy F, Moeller P, Bavaria JE.: Durability of Porcine Bioroots in Younger Patients With Aortic Root Pathology: A Propensity Matched Comparison With Composite Mechanical Roots. Society of Thoracic Surgeons Meeting, Ft Lauderdale, FL January 2010.
  17. Bavaria JE, Szeto W, Roche L, Walsh E, Burtch K, Desai ND, Herrmann HC: The impact of a transcatheter valve program: Outcome of nearly 600 referrals. Southern Thoracic Surgery Association Meeting 2010.
  18. Desai ND, McCarthy F, Szeto W, Pochettino A, Erwin R, El-Sayed Y, Bavaria, J: Hemodynamic performance of biologic root replacements: pericardial composite v. Porcine bioroots. Aortic Surgery Symposium 2010.
  19. Milewski RK, Jassar AS, Pochettino A, Szeto WY, Desai ND, Moeller PJ, Gorman JH, Bavaria JE: The reoperative aortic root: Degenerative failure vs. Infectious destruction - Outcomes of the "true redo-root" reconstruction. Aortic Surgery Symposium 2010.
  20. Moeller P, Szeto WY, Moser G, Desai ND, Acker, MA, Pochettino A, Bavaria, JE: Endovascular repair of the ascending aorta. Aortic Surgery Symposium 2010.
  21. Wallen RJ, Szety WY, Desai ND, Sodhi N, Moeller P, Pochettino A, Bavaria JE: The use of thoracic endovascular stent grafting (TEVAR) in acute aortic tragedies as compared to open surgical repair. Aortic Surgery Symposium 2010.
  22. Desai ND, Burtch K, Moeller P, Moser WG, Pochettino A, Woo E, Fairman RM, Szety WY, Bavaria JE: Long-term comparison of TEVAR to open surgery for the treatment of thoracic aneurysm. American Association for Thoracic Surgery May 2011.
  23. Desai ND, Moser W, Moeller P, Szeto W, Wang G, Woo E, Pochettino A, Bavaria J: Renal dysfunction and TEVAR: Risk factors and prognostic impact in large prospective cohort. American Heart Association Scientific Sessions 2011 June 2011.
  24. Desai ND, Pochettino A, Szeto W, Moeller P, Moser W, Bavaria, J: Early and late results of operative management of type A aortic dissection in higher risk patients. American Heart Association Scientific Session 2011 November 2011.
  25. Bavaria J, Desai ND, Burtch K, Vuong D, Morris R, Szeto W: Two year results of the St. Jude medical trifecta pericardial aortic valve bioprosthesis. Society of Heart Valve Disease 2011.
  26. Bavaria J, Desai ND, Szeto W, Sodhi N, Lazar SF, Robin L, Walsh L, Bannan A, Herrmann H: Hemodynamic comparison of aggressive supra-annular surgical aortic valve replacement versus transcatheter aortic valve implantation. Society of Heart Valve Disease 2011.
  27. Desai ND, McCarthy F, Pochettino A, Mitchell A, Selvin E, Szeto W, Bavaria J: Mild and moderate mitral regurgitation during aortic root reconstruction: The dilemma of annuloplasty. Society of Heart Valve Disease 2011.
  28. McCarthy F, Pochettino A, Mitchell A, Selvin E, Szeto W, Desai ND, Bavaria J: Stentless porcine bioroots v. pericardial composite roots v. mechanical composite roots: hemodynamic comparison and ventricular remodeling in aortic root replacement surgery. Society of Heart Valve Disease 2011.
  29. Desai ND: Retrograde aortic dissection after thoracic endovascular aortic repair: Incidence of a new disease. AATS Aortic Symposium April 2012.
  30. Desai ND: Early and late results of operative management of type A aortic dissection in higher risk patients. AATS Aortic Symposium April 2012.
Editorials, Reviews, Chapters, including participation in committee reports (print or other media)
  1. Desai ND, Christakis GT: Bioprosthetic and mechanical aortic valve replacement. Chap. 38 in Cardiac Surgery in the Adult, Second Edition. Cohn LH, Edmunds LH Jr. (eds.). New York: McGraw Hill, Page: 951-986, 2002.
  2. Desai ND, Fremes SE: Off-pump versus on-pump coronary bypass surgery. [Commentary/ Letter]. New England Journal of Medicine 350(17): 1791-1793, April 2004.
  3. Desai ND: Invited commentary. [Commentary]. Annals of Thoracic Surgery 80(6): 2192-2193, December 2005.
  4. Desai ND: The origins of heart surgery. Heart Surgery in Canada: Anecdotes, History & Perspective. Goldman BS, Belanger S (eds.). New York: Xlibris Press, Page: 18-29, 2005.
  5. Desai ND, Fremes SE: Efficacy and safety of edifoligide. [Commentary/ Letter]. Journal of the American Medical Association 295(13): 1514, April 2006.
  6. Desai N, Fremes SE: Comment on "Intraoperative indocyanine green angiography: Ready for prime time?" in JTCS 2007;133:592-3. [Commentary/Letter]. Journal of Thoracic & Cardiovascular Surgery 133(5): 1396-1397, May 2007.
  7. Desai ND, Christakis GT: Bioprosthetic aortic valve replacement: Stented pericardial and porcine valves. Chap. 34 in Cardiac Surgery in the Adult, Third Edition. Cohn LH, Edmunds LH Jr. (eds.). New York: McGraw Hill, Page: 857-894, 2007.
  8. Desai ND: Pitfalls assessing the role of drug-eluting stents in multivessel coronary disease. [Commentary]. Annals of Thoracic Surgery 85(1): 25-27, January 2008.
  9. Desai ND: Comment on Levine et al. "Rescue percutaneous coronary intervention for graft failure immediately after coronary artery bypass grafting: Case report and review of literature." [Commentary]. Journal of Cardiovascular Surgery 23(6): 713, November/December 2008.
  10. Stein E, Daigle S, Weiss SJ, Desai ND, Augoustides JG: Successful management of a complicated traumatic ventricular septal defect. Journal of Cardiothoracic and Vascular Anesthesia 25(3): 547-552, June 2011 Notes: [Case Report]

Dr. Nimesh Desai

 
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