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Kristoffel R. Dumon, M.D.
Gastrointestinal Surgery

 
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Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
4 Silverstein Pavilion
Philadelphia, PA 19104
Administrative Assistant: Shakira Tucker
Administrative Telephone:
215-662-2029
Administrative Fax: 215-349-8195
Patient Appointments: 215-662-2626

Clinical Office:
Perelman Center for Advanced Medicine
GI Surgery
West Pavilion, 4th Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104

Contact Information (internal use only)

dumonk@uphs.upenn.edu

 

Dr. Kristoffel Dumon joined the Division of Gastrointestinal Surgery in the Department of Surgery. His clinical interests include minimally invasive surgery and weight loss surgery. Dr. Dumon completed his Surgery residency at the University of Pennsylvania in 2006 which included a research fellowship in surgical oncology and a clinical fellowship in Minimally Invasive and Bariatric Surgery. As a member of the the Bariatric Surgery Program, Dr. Dumon and the Bariatric Surgery Team at Penn offer comprehensive medical care for morbidly obese patients before and after surgery. The expertise of professionals in psychology, nutrition, medicine, nursing and surgery are the core components of the program. The PENN Bariatric Surgery team works together to provide the patient with the best medical care, while achieving lifestyle and weight loss goals.  

His clinical research interests include the multidisciplinary management of bariatric patients, the use of new technologies such as endoluminal strategies and robotic surgery for the treatment of Bariatric patients. He also investigates clinical outcome with bariatric surgery and is involved with patient safety and quality improvement research in this field. He has authored numerous journal articles and textbook chapters related to his clinical and basic research interests. In addition to his clinical activities, Dr Dumon continues to be heavily involved with resident education and the development of a comprehensive surgical skills curriculum for residents in surgery.

 
Faculty Appointments
2007 - present Assistant Professor of Surgery at HUP
Perelman School of Medicine
Philadelphia, Pennsylvania
 
2005 - 2007 Instructor in Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1998 - 2005 Assistant Instructor in Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1999 - 2001 Research Fellow, Harrison Department of Surgical Research
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1995- 1998 Research Instructor in Clinical and Experimental Surgery
Heinrich Heine University, Duesseldorf
 
1995 - 1998 Instructor in Surgery
Heinrich Heine University, Duesseldorf, Germany
 
1994 - 1998 Lecturer in Pediatric Surgery
Heinrich Heine University, Duesseldorf, Germany
 
Hospital and Administrative Appointments
2014 - present Interim Director, Penn Simulation Center at Rittenhouse Square
 
2014 - present Course Director, Surgical Simulation, Measy Surgical Simulation Center
 
2014 - present Director Fundamentals of Laparoscopic Surgery Skills Course, Measy Skills Center
 
2011 - 2014 Chief of Surgery, Philadelphia VA Medical Center
Philadelphia VA Medical Center   
 
2011 - present Section Chief General Surgery, Philadelphia VA Medical Center
Philadelphia VA Medical Center   
 
2006 - present  Attending Surgeon, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2006 - present  Attending Surgeon, Philadelphia VA Medical Center
Philadelphia, Pennsylvania
 
2006 - present  Associate Director, Department of Surgery Simulation Center
 
2006 - 2012 Associate Course Coordinator, Surgery Simulation Curriculum
 
2007 - present Course Director FLS Course
 
Education/Training
1983 - 1990 MD - Katholieke Universiteit Leuven, Belgium (Medical School)
 
  Faculty of Medicine, Minderbroederstraat 13, 3001
Leuven, Belgium
 
  Surgical Resident, General and Trauma Surgery
Director: Prof. Dr. med. H.-D. Rher, Klinik fr Allgemein- und Unfallchirurgie der
Heinrich-Heine Universitt, Dsseldorf, Germany
 
Postgraduate Training and Fellowship Appointments
2005 - 2006 Chief Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2004 - 2005 Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2003 - 2004 Fellowship in Bariatric Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2001 - 2003 Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1999 - 2001 Research Fellow
Harrison Department of Surgical Research
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1998 - 1999 Internship in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1992 - 1998 Resident in General and Trauma Surgery
Heinrich-Heine Universitaet
Duesseldorf, Germany
 
1991 - 1991 Resident in Anesthesiology
Katholieke Universiteit
Leuven, Belgium
 
Memberships/Societies
 
Memberships in Professional and Scientific Societies
  • Orde Der Geneesheren, Belgium
  • Deutsche Gesellschaft Fuer Chirurgie, Germany
  • Founding Member Deutsche Gesellschaft fuer Moleculare Chirurgie, Germany
  • (In Process) Member Society of American Gastrointestinal Endoscopic Surgeons (SAGES)
  • (In Process) Member American Society of Metabolic and Bariatric Surgeons (ASMBS)
  • (In Process) Member Association for Academic Surgeons
  • Member American College of Surgeons Educational Institutes
  • FACS American College Of Surgeons, USA
  • Member, ASMBS Center of Excellence
 
Research
Dr Dumon’s basic science research focuses on the immune mechanisms and inflammatory response in the surgical patient and the molecular basis of pancreatic cancer. His clinical research interests include the multidisciplinary management of bariatric patients, the use of new technologies such as endoluminal strategies and robotic surgery for the treatment of Bariatric patients. He also investigates clinical outcome with bariatric surgery and is involved with patient safety and quality improvement research in this field. He is currently involved with research looking at the value and impact of formal surgical skills education for the training of surgical residents. He has authored numerous journal articles and textbook chapters related to his clinical and basic research interests.
 
Publications
Research Publications, peer reviewed
  1. Goretzki PE, Gorelov VN, Weißmann K, Dumon K, Ebeling B, Simon D, Gynes M, Palm D, Mollner S, Pfeuffer T, Bosilij B, Lyons J, Röher H-D Mutation and expression of alpha Gs in differential thyroid carcinoma (DTC) and medullary thyroid carcinoma (MTC). Exp. Clin. Endocrinol. 101:54-59, 1993. 
  2. Dumon K, Barteneva NS, Gorelov VN, Palm D, Röher H-D, Goretzki PE Overexpression of Growth-Stimulating GTP-Binding Proteins (GSP/Ras) in the Presence of Mutations: The Possiblity of future Simple Screening Procedures. Langenbecks Arch Chir Suppl I. 345-348, 1994.
  3. Dumon K, Barteneva NS, Gorelov VN, Gross-Weege W, Röher H-D, Goretzki PE Frühzeitige Identifizierung von Methicillin-Oxacillin-resistenten Staphylococcus aureus-Stämmen mittels Polymerase Chain Reaction (PCR). Ein diagnostisches Verfahren mit klinscher Bedeutung. Langenbecks Arch Chir Suppl I.  497-499, 1995.
  4. Gorelov VN, Dumon K, Barteneva NS, Palm D, Röher H-D, Goretzki PE Overexpression of Gs alpha subunit in thyroid tumors bearing a mutated Gs alpha gene. J Cancer Res Clin Oncol 121: 219-224 , 1995.
  5. Willnow U, Dumon K., Godehart E. Effect of hyperthermia 42.5°C/120 min on 3H-thymidine incorporation in different tissue components of Wilms´ tumors: An in vitro study. Klin. Padiatr. 208 (4) 145-150, 1996.
  6. Gorelov VN, Dumon K, Barteneva NS, Röher H-D, Goretzki PE. A  modified PCR-based method for rapid non-radioactive detection of clinical important pathogens. Microbiol. Immunol 40 (9) 611-616, 1996.  
  7. Dumon K, Gorelov VN, Gross-Weege W, Röher H-D, Goretzki PE  Sensitive, rapid and species specific PCR-based method for the early identification of nosocomial infections in surgical intensive care patients. Langenbecks Arch Chir . 391-394, 1996.
  8. Dumon K, Gorelov VN, Gross-Weege W, Unger A., Füth R, Röher H-D, Goretzki PE Use of  a PCR-oriented method for early detection of nosocomial infections in surgical intensive care patients. Langenbecks Arch Chir. 114:369-372, 1997.
  9. Gross-Weege W, Weiss M, Schneider M, Wenning M, Harms B, Dumon K, Ohmann C, Röher H.-D. (1997) Safety of a low-dosage Filgrastim (rhG-CSF) treatment in non-neutropenic surgical intensive care patients with an inflammatory process. Intensive Care Med  23:16-22, 1997.
  10. Willnow U, Dumon K.  In Vitro Study on the Effect of Hyperthermia (42,5, 120 min) and Cytostatic Agents on the DNA- and RNA-Synthesis of Embryonal Tumors and Sarcomas in Children. Langenbecks Arch Chir , 1100-1101, 1997.
  11. Gross-Weege W, Dumon K, Dahmen A, Schneider EM, Röher HD.Granulocyte Colony-Stimulating Factor (G-CSF) Serum Levels in Surgical Intensive Care Patients. Infection 25: 213-216, 1997.
  12. Dumon K, Roßbach C, Harms B, Gorelov V, Groß-Weege W, Schneider EM, Goretzki PE, Röher HD: Tumornekrosefaktor-alpha (TNF-alpha) Gen-Polymorphismus bei chirurgischen intensivpatienten mit SIRS Langenbecks Arch Chir. 359-363, 1998.
  13. Gross-Weege W, Dumon K, Harms B, Segendorf C, Schneider EM, Raffel A, Sandmann W, Röher HD. Does the prophylactic administration of filgrastim (rmetHuG-CSF) reduce infectious complications in surgical intensive care patients? Langenbecks Arch of Surg 499-50, 1999.
  14. Gorelov V, Bulankin A, Fischer U, Dumon K, Hohndorf L, Baersch G, Liebig B, Heins S, Hattenhorst U, Rainov N, Kramm C, Burdach S. Stable transgenic expression of IL2 and HSV1-TK by single and fusion tumor cell lines bearing ews/fli1 chimeric genes. Human Gene Therapy, 2000
  15. Dumon KR, Chakrani F, During MJ, Rosato EF, Williams NN, Croce CC. Inhibition of tumor growth and induction of apoptosis by adeno associated virus mediated fragile histidine triade (FHIT) gene overexpression in pancreatic cancer cell lines. Gastroenterology 118 (4): 643-643 3271, 2000
  16. Ishii H, Dumon K, Vecchione A, Trapasso F, Miomori K, alder H, Mori M, Sozzi G, Baffa R, Huebner K, Croce CM. Effect of adenoviral transduction of the fragile histidine triade gene into esophageal cancer cells.  Cancer Research, 61(4): 1578-84, 2001
  17. Dumon K, Ishii H, Vecchione A, Trappazo F, Baldassarre G, Chakrani F, Druck T, Rosato EF, Williams NN, Baffa R, During M, Huebner K, Croce CM. Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer Cancer Research, 61(12) 4827-36, 2001
  18. Dumon K, Ishii H, Fong LY, Zanesi N, Fidanza V, Mancini R, Vecchione A, Baffa R, Trappazo F, During M, Huebner K, Croce CM FHIT Gene Therapy Prevents Tumor Development in Fhit-deficient Mice. PNAS 98(6) 3346-51,2001
  19. Ishii H, Dumon K, Vecchione A, Fong LY, Baffa R, Huebner K, Croce CM. Potential cancer therapy with the fragile histidine triad gene: review of the preclinical trails JAMA 286(19):2441-9,2001
  20. Ishii H, Dumon K, Vecchione A, Fong LY, Baffa R, Huebner K, Croce CM. Potential cancer therapy with the fragile histidine triad gene: review of the preclinical trials JAMA 286(19):2441-9,2001
  21. Staege MS, Gorelov V, Bulankin A, Fischer U, Dumon K, Hohndorf L, Hattenhorst U, Kramm C, Burdach S. Stable transgenic expression of IL-2 and HSV1-tk by single and fusion tumor cell lines bearing EWS/FLI-1 chimeric genes. Pediatric Hematology And Oncology 20 (2): 119-140 2003
  22. Weiss M, Voglic S, Harms-Schirra B, Lorenz I, Lasch B, Dumon K, Gross-Weege W, Schneider EM. Effects of exogenous recombinant human granulocyte colony-stimulating factor (filgrastim, rhG-CSF) on neutrophils of ill patients with systemic inflammatory response syndrome depend on endogenous G-CSF plasma concentrations on admission. Intensive Care Medicine 29 (6): 904-914  2003
  23. Iuliano R, Trapasso F, Le Pera I, Schepis F, Sama I, Clodomiro A, Dumon KR, Santoro M, Chiariotti L, Viglietto G, Fusco A An adenovirus carrying the rat protein tyrosine phosphatase eta suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo. Cancer Research 63 (4): 882-886, 2003
  24. Yendamuri S, Kuroki T, Trapasso F, Henry A, Dumon K, Huebner K, Williams NN, Kaiser LR, Croce CM. WW Domain containing oxidoreductase gene expression is altered in non-small cell lung cancer. Cancer Research 63: 878-881, 2003
  25. Yendamuri S, Trapasso F, Calin G, Kuroki T, Dumon K, Williams N, Kaiser L, Croce C. ALTS1 is downregulated in non-small cell lung cancer, and its restoration inhibits growth And Suppresses Tumorigenicity In Lung Cancer Cell Lines Journal Of The American College Of Surgeons 197 (3): 29-31, 2003
  26. Yendamuri S, Kuroki T, Trapasso F, Rattan S, Dumon K, Williams N, Croce C. WW domain containing oxidoreductase (WWOX) gene in human pancreatic cancer. Journal Of The American College Of Surgeons 197 (3): 76, 2003
  27. Dumon KR, Metz D, Kochman ML, Williams NN. The role of therapeutic endoscopy for postoperative management of obstructive symptoms after hand assisted Roux-en-Y-gastric bypass. Gastrointestinal Endoscopy 59 (5): 137, 2004
  28. Trapasso F, Yendamuri S, Dumon KR, Iuliano R, Cesari R, Feig B, Seto R, Infante L, Ishii H, Vecchione A, During MJ, Croce CM, Fusco A Restoration of receptor-type protein tyrosine phosphatase eta function inhibits human pancreatic carcinoma cell growth in vitro and in vivo. Carcinogenesis 25 (11): 2107-2114 2004
  29. Trapasso F, Sarti M, Cesari R, Yendamuri S, Dumon KR, Aqeilan RI, Pentimalli F, Infante L, Alder H, Abe N, Watanabe T, Viglietto G, Croce CM, Fusco A. Therapy of human pancreatic carcinoma based on suppression of HMGA1 protein synthesis in preclinical models. Cancer Gene Therapy 11 (9): 633-641 p 2004
  30. Dumon KR, Traynor O, Broos P, Gruwez JA, Darzi AW, Williams NN. Surgical education in the new millennium: the European perspective.  Surgical Clinics Of North America 84 (6): 1471-1479 Dec 2004
  31.  S Jha, MS Levine, SE Rubesin, K Dumon, ML Kochman, I Laufer, NN WilliamsDetection of strictures on upper gastrointestinal tract radiographic examinations after laparoscopic Roux-en-Y gastric bypass surgery: importance of projection. American Journal of Roentgenology 186 (4), 1090-1093; 2006
  32. Ashish C. Sinha, M.D., Ph.D., Min Wang, B.A., Kristoffel R. Dumon, M.D., Noel N. Williams, M.D.: Incidence of Post Operative Nausea and Vomiting in the Extremely Obese after Weight Loss Surgery. 107: 1053 Anesthesiology 2007
  33. Kristoffel R Dumon, MD; Katie Foster-Kilgarriff, MSN, CRNP; Diane Filter, MSN, MPH; Steven E Raper, MD, FACS; Noel N Williams, MD, FRCSI  The Implementation Of A Designated Bariatric Surgery Program Leads To Improved Clinical Outcomes, Surgery for Obesity and Related Diseases 3 (3), 356; 2007
  34. Kristoffel R Dumon, MD; Katie Foster-Kilgarriff, MSN, CRNP; Diane Filter, MSN, MPH; Noel N Williams, MD, FRCSI, Hand-Assisted Laparoscopic Roux-En-Y Gastric Bypass: Results Of 1000 Cases. Surgery for Obesity and Related Diseases 3 (3), 356-357; 2007
  35. Roy J Kim, MD, MPH; Jessica M Langer; Kristoffel Dumon, MD; Diane E Filter, MSN, MPH; David B Sarwer, PhD; Noel N Williams, MB, BCh, M Clinical Outcomes For Adolescents Undergoing Bariatric Surgery. Surgery for Obesity and Related Diseases 3 (3), 306; 2007 
  36. Sai Yendamuri, Francesco Trapasso, Manuela Ferracin, Rossano Cesari, Cinzia Sevignani, Masayoshi Shimizu, Shashi Rattan, Tamotsu Kuroki, Kristoffel R. Dumon, Florencia Bullrich, Chang-gong Liu, Massimo Negrini, Noel N. Williams, Larry R. Kaiser, Carlo M. Croce and George A. Calin Tumor Suppressor Functions of ARLTS1 in Lung Cancers, Cancer Res. 2007 Aug 15;67(16):7738-45.
  37. Paul J Foley, Kristoffel R Dumon, Robert E Roses, Olanrewaju Olaoye, Rajesh Aggarwal, Ara W Darzi, James L Mullen, Larry R Kaiser, Jon B Morris, Noel N Williams. A dedicated one-month laparoscopic and endoscopic skills rotation significantly improves surgical residents' technical skill and reduces error scores Journal of the American College of Surgeons 207 (3); 2008
  38. Herdrich, Benjamin J., Dumon, Kristoffel R., Morris, Jon B., Williams, Noel N. Simulation rotation offers junior surgical residents a perceived improvement in technical training compared to traditional training models. Journal of the American College of Surgeons 207 (3); 2008
  39. Mittal, Mayank K. Dumon, Kristoffel R. Herdrich, Benjamin J. Okusanya, Olugbenga T. Hashimoto, Daniel A. Olaoye, Olanrewaju Resnick, Andrew S. Murayama, Kenric M. Williams, Noel N. A novel bronchoscopy training curriculum for junior surgical residents improves quality and efficiency of simulated bronchoscopy Journal of the American College of Surgeons 209 (3); 2009
  40. Mittal, Mayank K. Dumon, Kristoffel R. Okusanya, Olugbenga T. Hashimoto, Daniel A. Resnick, Andrew S. Murayama, Kenric M. Williams, Noel N. Immediate global performance enhancement in open surgical skills of junior surgical residents undergoing a dedicated monthly surgical skills training curriculum Journal of the American College of Surgeons  209 (3), 116-117; 2009
  41. Okusanya, Olugbenga T. Dumon, Kristoffel R. Mittal, Mayank K. Kelz, Rachel R. Hashimoto, Daniel A. Olaoye, Olanrewaju Resnick, Andrew S. Murayama, Kenric M. Williams, Noel N. Establishment of resident laparoscopic virtual reality skills proficiency Journal of the American College of Surgeons 209 (3); 2009
  42. Swenson DW, Levine MS, Rubesin SE, Williams NN, Dumon K. Utility of routine barium studies after adjustments of laparoscopically inserted gastric bands. AJR Am J Roentgenol.; 194(1):129-35, 2010.
  43. Ruutiainen AT, MS Levine, K Dumon. Intraluminal erosion and retrograde migration of laparoscopic gastric band with high-grade obstruction at gastroesophageal junction Surgery for Obesity and Related Diseases 8 (2), 14-16; 2012
  44. NN Williams, MK Mittal, KR Dumon, G Matika, LA Pray, AS Resnick, JB Morris. Penn Medicine Clinical Simulation Center. Journal of surgical education 68 (1), 83-86; 2011
  45. Edelson PK, Dumon KR, Sonnad SS, Shafi BM, Williams NN.  Robotic vs. conventional laparoscopic gastric banding: A comparison of 407 cases.  Surgical Endoscopy 25(5):1402-1408, May 2011 (Epub Oct. 26, 2010). 
  46. Dumon KR, Edelson PK, Raper SE, Foster-Kilgarriff K, Williams NN.  Implementation of designated bariatric surgery program leads to improved clinical outcomes.  Surgery for Obesity & Related Disorders 7(3):2711-2716, 2011 (Epub Feb. 26, 2011).
  47. A Mittal, Mayank K.; Kreitz, Keith A.; Resnick, Andrew S.; Morris, Jon B.; Williams, Noel N.; Dumon, Kristoffel R. Novel Approach for Augmenting Percutaneous Endoscopic Gastrostomy Tube Placement Training  Simulation in Healthcare: The Journal of the Society for Simulation in Healthcare. 5(6):346-349, 2010.
  48. KR Dumon, KM Murayama Bariatric surgery outcomes. Surgical Clinics of North America 91 (6), 1313-1338; 2011
  49. Danzer E, Dumon K, Kolb G, Pray L, Selvan B, Resnick AS, Morris JB, Williams NN.  What is the cost associated with the implementation and maintenance of an ACS/APDS-based surgical skills curriculum?  Journal of Surgical Education 68(6):519-525, 2011.
  50. Vetter ML, Dumon KR, Williams NN.  Surgical treatments for obesity. Psychiatric Clinics of North America 34(4):881-893, 2011.
  51. Mittal MK, Dumon KR, Edelson PK, Acero NM, Hashimoto D, Danzer E, Selvan B, Resnick AS, Morris JB, Williams NN. Successful implementation of the american college of surgeons/association of program directors in surgery surgical skills curriculum via a 4-week consecutive simulation rotation. Simul Healthc;7(3):147-54, 2012
  52. Hashimoto DA, Gomez ED, Danzer E, Edelson PK, Morris JB, Williams NN, Dumon KR. Intraoperative resident education for robotic laparoscopic gastric banding surgery: a pilot study on the safety of stepwise education J Am Coll Surg. Jun;214(6):990-6: 2012
  53. Acero NM, Motuk G, Luba J, Murphy M, McKelvey S, Kolb G, Dumon KR, Resnick AS. Managing a surgical exsanguination emergency in the operating room through simulation: an interdisciplinary approach.J Surg Educ.;69(6):759-65, 2012
  54. Karlin Bark, Ernest D Gomez, Charlotte Rivera, William McMahan, Austin C Remington, Kenric M Murayama, David I Lee, Kristoffel R Dumon, Noel N Williams, Katherine J Kuchenbecker Surgical instrument vibrations are a construct-valid measure of technical skill in robotic peg transfer and suturing tasks. Proc. Medical Robotics. 50-51, 2012
  55. JA Cintolo, MS Levine, S Huang, K Dumon. Intraluminal Erosion of Laparoscopic Gastric Band Tubing into Duodenum with Recurrent Port-Site Infections. Journal of Laparoendoscopic & Advanced Surgical Techniques 22 (6), 591-594; 2012
  56. Choudhury RA, Murayama KM, Abt PL, Glick HA, Naji A, Williams NN, Dumon KR. Roux-en-Y gastric bypass compared with aggressive diet and exercise therapy for morbidly obese patients awaiting renal transplant: a decision analysis. Surg Obes Relat Dis. 2014 Jan-Feb;10 (1):79-87.
  57. Bromberger B, Porrett P, Choudhury R, Dumon K, Murayama KM
  58. Weight loss interventions for morbidly obese patients with compensated cirrhosis: a Markov decision analysis model. J Gastrointest Surg. 2014 Feb; 18(2):321-7.
  59. William McMahan, Ernest D. Gomez, Liting Chen, Karlin Bark, John C. Nappo, Eza I. Koch, David I. Lee, Kristoffel R. Dumon, Noel N. Williams, Katherine J. KuchenbeckerA practical system for recording instrument interactions during live robotic surgery, Journal of Robotic Surgery, April p 1-8; 2013
  60. Dumon K, Savulionyte G. Bariatric surgery produces greater weight loss and improvements in medical conditions than non-surgical treatment of obesity. Evid Based Med. 2014 Aug;19(4):138.
  61. Rashikh A Choudhury RA, Murayama KM, Neylan CJ, Savulionyte G, Glick H, Williams NN, Dempsey DT, Dumon KR. Re-examining the BMI Threshold for Bariatric Surgery in the United States. Journal of Gastrointestinal Surgery, 2014,(Accepted with Revisions)
  62. Rashikh Choudhury, Chris Neylan, Uma Kannan, Linden Karas, Noel Williams, Kristoffel Dumon.  Robotic-Assisted vs. Hand-Assisted Laparoscopic Sleeve Gastrectomy Performed by Surgical Residents.  Surgical Endoscopy. 2013 (Submitted)
  63. Umashankkar Kannan, Noel N Williams, Daniel T Dempsey, Kristoffel R Dumon. Robot-Assisted vs. Hand-Assisted Laparoscopic Sleeve Gastrectomy: Comparison of 108 cases. Surgical Endoscopy 2014, (Submitted)
Abstracts (selection of peer reviewed)
  1. Dumon K, Orr MD, Merwin J Allosteric subunit strucuture of the acetylcholine receptor protein at the neuromuscular junction.  A computer simulation.  American Society of Anesthesiologists, 1990 Annual Meeting. Las Vegas, October 19-23. Congressissue: P. 362., 1990
  2. Dumon K, Orr MD. Serotonin Receptors: Strucuture and  Function.American Society of Anesthesiologists, 1993 Annual Meeting. Washington, D.C., October 9-13. Congressissue: P. 234.,1993
  3. Gorelov VN, Barteneva NS, Dumon K, Palm D, Röher H-D, Goretzki P,  Wenzel BE  A point mutation of the Gs-a gene in thyroid  tissue from patients with  graves´disease (GD): correlation with the level of expression of Gsa-proteins. Sixty Eighth Annual Meeting. The American Thyroid Association, Chicago, Illinois. September 28th - october 1st, 1994.    Congressissue: S-37, 1994
  4. Dumon K, Gross-Weege W, Buscher S, Ohmann C, Becker H  A Computer based program for monitoring severity of illness in surgical intensive care patients with SIRS or sepsis at admission. Clin Int Care 5 Suppl(2): 118, 1994
  5. Dumon K, Gross-Weege W, Buscher S, Ohmann C, Becker H A computer based program for monitoring severity of illness in SICU patients: evaluation of 220 consecutive cases. Intensive Care Med. 20 Suppl(2): S7, 1994
  6. Dumon K, Barteneva N, Gorelov V, Gross-Weege W, Goretzki P Early identification of Methicillin-Resistant Staphylococcus aureus by Polymerase Chain Reaction (PCR). A diagnostic procedure of clinical importance. Curr Opin Surg Inf 3 Suppl(1): S30, 1995
  7. Gross-Weege W, Dahmen A, Dumon K, Ohmann C  Failure of granulocyte colony-stimulating factor (G-CSF) increase in surgical intensive care patients with sepsis. Curr Opin Surg Inf 3 Suppl(1): S 12, 1995
  8. Lorenz I, Dumon K, Khanna R, Scharf RE, Schneider EM Systemic versus local      inflammatory cytokines. Concentration of interleukin-8 (IL-8), interleukin-6 (IL-6) and the soluble interleukin-6 receptor (sIL-6R,p80) in patients with sepsis and septic shock Immunol. Letters 56: S31, 1997
  9. Harms B, Groß-Weege W, Dumon K, Scharf RE, Schneider EM Soluble CD62e as a measure of an attenuated inflammatory response in sepsis patients treated with G-CSF. Immunol Letters 56: S168, 1997
  10. Harms B, Groß-Weege W, Dumon K, Segendorf C, Schneider EM Surface bound soluble CD62E in intensive care patients treated with and without G-CSF Acta Haematologica 98 (suppl 1): 73, 1997
  11. Harms B, Dumon K, Groß-Weege W, Lorenz I, Röher HD, Scharf  RE, Schneider EM Effect of G-CSF-treatment for the prophylaxis of sepsis on the reconstitution of CD14, on neutrophil presensitization and on non-impaired phagocytic function in patients with extended surgery, trauma and hemorrhagic shock. Shock 7 (suppl): 79, 1997
  12. Gross-Weege W, Dumon K, Segendorf C, Harms B, Schneider EM, Röher HD Randomized trial with filgrastim (r-metHuG-CSF) for the prophylaxis of sepsis in surgical intensive care patients. Shock 7 (suppl): 81, 1997
  13. Lorenz I, Dumon K, Khanna R, Gross-Weege W, Scharf RE, Schneider EM Interleukin-8 (IL-8), interleukin-6 (IL-6) and interleukin-6 receptor (sIL-6R,p80) levles as prognostic factors for trauma and infectious complications after surgery Shock 7 (Suppl): 102, 1997
  14. Dumon K, Gorelov VN, Gross-Weege W, Unger A, Füth R,  Röher H-D, Goretzki PE A modified PCR-based method for the early detection of clinical pathogens in surgical intensive care patients  Shock 7 (Suppl): 12, 1997
  15. Gross-Weege W, Asgari S, Dumon K, Röher HD. (1997) Prävalenz und Prognose von SIRS bei laparotomierten Patienten der Intermediate Care Station. Intensivmedizin u. Notfallmedizin 34: 20, 1997
  16. Segendrof C, Gross-Weege W, Dumon K, Harms B, Schneider EM, Hartrung T, Wendel A, Sandmann W, Röher HD Randomisierte Studie mit Filgrastim (r-metHuG-CSF) zur Prophylaxe der Sepsis bei chirurgischen Intensivpatienten. Intensivmedizin u. Notfallmedizin 34: 49, 1997 
  17. Dumon K, Roßbach C, Lorenz I, Harms B, Gorelov V, Gross-Weege W, Röher HD,Schneider EM. : Tumornekrosefaktor-alpha (TNF-a) Gen Polymorphismus und Zytokin-Expression bei chirurgischen Intensivpatienten mit SIRS. Intensivmedizin u. Notfallmedizin 34: 49, 1997 
  18. Gorelov V, Dumon K, Spengler HP, Fischer U, Buttlies B, Genutt P, Wieczorec U, Heidmann O, Engel B, Kramm C, Burdach S. Genneration of ewing tumor cell line with stabel expression of IL2 und HSV1-TK. Annals of Hematology, S 15, 1998 
  19. Gorelov V, Fisher U, Dumon K, Kramm C, Burdach S. Transgenic expression of IL2 and HSV1-TK by EWS/FLI-1 expressing tumor cell lines and presentation of EWS/FLI1 fusion peptides as tumor antigens by dendritic cells. American Society of Gene Therapy 2nd Annual Meeting, June 9-13, 1999 Abstract Band p.107, 1999 
  20. Trapasso F, Luliano R, Le Pera I, Dumon K, Santoro M, Viglietto G, Fusco A, Croce CM. Tumor Suppressor Activity of A Receptor-Type Protein Tyrosine Phosphatase in Epithelial Carcinomas. Proceedings of the American Association for Cancer Research, 41, 745, 2000 
  21. Dumon K, Chakrani F, During MJ, Rosato EF, Williams NN, Croce CM. Inhibition of Tumor Growth and Induction of Apoptosis by Adeno Associated Virus Mediated Fragile Histidine Triade (FHIT) Gene Overexpression in Pancreatic Cancer Cell Lines. Gastroenterology, Suppl A-636, 2000. 
  22. Dumon K, Williams NN, Croce C.  Inhibition of tumor growth and induction of apoptosis by adeno-associated virus-mediated fragile histidine triade (FHIT) gene overexpression in pancreatic cancer cell lines.  Gastroenterology 2000.
  23. Dumon K, Williams NN.  Surg-Assist device (SSAT/AGA).  Gastroenterology 2001.
  24. Dumon K, Markmann J, Williams.  Comparison of hand-assisted donor nephrectomy with totally laparoscopic and open donor nephrectomy.  Surgical Endoscopy 2002.
  25. Dumon K, Williams NN.  Results of 154 Consecutive Hand Assisted laparoscopic Roux-en-Y Gastric Bypasses to Treat Morbid Obesity.  Surgical Endoscopy 2003.
  26. Yendamuri S, Kuroki M, Trapasso F, Rattan S, Dumon K, Williams NN, Croce C. The WW domain containing Oxidoreductase (WWOX) gene is altered in Pancreatic Cancer. JACS  2003;197:S76.
  27. Yendamuri S, Trapasso F, Calin G, Kuroki T, Dumon KR, Williams NN, LR Kaiser, CM Croce. ALTS1 is downregulated in non-small cell lung cancer and its restoration inhibits growth and suppresses tumorigenicity in lung cancer cell lines. JACS. 2003;197:S29.
  28. Dumon K, Metz D, Kochman M, Williams NN.  The role of therapeutic endoscopy for postoperative management of obstructive symptoms after hand assisted roux-en-y-gastric bypass. Gastroenterlogy 2004
  29. KR Dumon, SE Raper, D Filter, NN Williams. The impact of an institutional review panel on patient selection. How do panel decisions affect patient selection?  Surgery for Obesity and Related Diseases 4 (3), 343; 2008
  30. Foley PJ, Dumon KR, Roses RE, Olaoye O, Aggarwal R, Darzi A, et al. A dedicated one-month laparoscopic and endoscopic skills rotation significantly improves surgical residents' technical skill and reduces error scores. ; 207 (3, Supplement 1):S94. Research Presented at the 94th Annual Clinical Congress, American College of Surgeons 2008
  31. Herdrich BJ, Dumon KR, Morris JB, Williams NN. Simulation rotation offers junior surgical residents a perceived improvement in technical training compared to traditional training models. ; 207(3, Supplement 1):S90. Research Presented at the 94th Annual Clinical Congress, American College of Surgeons 2008
  32. Mayank K Mittal, Scott W Cowan, Kristoffel R Dumon, Daniel A Hashimoto, Olugbenga Okusanya, Andrew S Resnick, Noel N Williams. Bronchoscopy guided tracheostomy a hybrid model providing airway training for residents. SAGES ; April 22- 25, 2009
  33. Mayank K Mittal, Daniel A Hashimoto, Olugbenga Okusanya, Peter McCombs, Andrew Resnick, Noel N Williams, Kristoffel R Dumon, MD. Harnessing simulation technology for scenario-based instruction of abdominal aortic aneurysm repairs. ; SAGES April 22-25th, 2009
  34. Mayank K Mittal, Noel N Williams, Keith A Kreitz, Olugbenga Okusanya, Daniel A Hashimoto , Andrew S Resnick, Kristoffel R Dumon. Low fidelity simulation model for percutaneous endoscopic gastrostomy (peg) tube placement. Sages emerging technology; SAGES April 22-25th, 2009
  35. Paula K Edelson, Bsc, Kristoffel R Dumon,MD, Seema S Sonnad, Phd, Bilal M Shafi, MD, Noel N Williams,Robotic Vs. Conventional Laparoscopic Gastric Banding: Acomparison Of 407 Cases; SAGES, 2010
  36. Mayank K Mittal, MD MRCS, Ben Selvan, MD MS, K R Dumon, MD, A S Resnick, MD, N N Williams, MD, J B Morris, MD, R R Kelz, MD MSCE, Cost Effective Simulation Based Endocrine Surgery Training Module SAGES, 2010
  37. B Selvan, K Dumon, JB Morris, A Resnick, M Mittal, NN Williams. High intensity, proctored interval training for junior surgical residents in fundamentals of laparoscopic surgery leads to the achievement of adequate proficiency levels comparable to the proficiency levels of senior residents. Journal of the American College of Surgeons 211 (3), S117-S118; 2010
  38. B Selvan, K Dumon, P McCombs, D Hashimoto, J Morris, A Resnick, N Williams PASS (Penn Assessment of Surgical Skills)-validation of a new tool to assess technical and nontechnical skills of surgical residents. Journal of the American College of Surgeons 213 (3), S126-S127; 2011
  39. DA Hashimoto, E Gomez, PK Edelson, E Danzer, JB Morris, NN Williams, KR Dumon. Intraoperative resident education for robotic laparoscopic gastric banding surgery. Journal of the American College of Surgeons 213 (3), S129-S130; 2011
  40. N Martinez, G Motuk, G Kolb, J Luba, KR Dumon, AS Resnick.Journal of the American College of Surgeons 215 (3), S112-S113; 2012
  41. Ernest D. Gomez, BS, BSE, Karlin Bark, PhD, Charlotte Rivera, William McMahan, MS, Austin Remington, David I. Lee, MD, Noel N. Williams, MD, FRCS, Kenric M. Murayama, MD, FACS, Kristoffel R. Dumon, MD, Katherine J. Kuchenbecker, PhD Construct validity of instrument vibrations as a measure of robotic surgical skill. Journal of the American College of Surgeons .Volume 215, Issue 3, Supplement , Pages S119-S120, 2012
  42. Ernest D. Gomez, Karlin Bark, Charlotte Rivera, William McMahan, Austin Remington, David I. Lee, Noel Williams, Kenric Murayama, Kristoffel Dumon, and Katherine J. Kuchenbecker. Construct validity of instrument vibrations as a measure of robotic surgical skill. Journal of the American College of Surgeons, 215(3):S119–120, 2012
  43. Karlin Bark, Ernest D. Gomez, Charlotte Rivera, William McMahan, Austin Remington, Kenric Murayama, David I Lee, Kristoffel Dumon, Noel Williams, and Katherine J. Kuchenbecker. Surgical instrument vibrations are a construct-valid measure of technical skill in robotic peg transfer and suturing tasks. In Proc. Hamlyn Symposium on Medical Robotics, 2012
  44. B Bromberger, K Dumon, RA Choudhury, P Porrett, K Murayama.Weight-Loss Interventions for Morbidly Obese Patients With Compensated Cirrhosis: A Markov Decision Analysis Model;Gastroenterology 144 (5), S-1125-S-1126; 2013
  45. Ernest D. Gomez, Rajesh Aggarwal, William McMahan, Eza Koch, Daniel. A. Hashimoto, Ara Darzi, Kenric M. Murayama, Kristoffel R Dumon, Noel N.Williams, and Katherine J. Kuchenbecker. Instrument contact vibrations are a construct-valid measure of technical skill in fundamentals of laparoscopic surgery training tasks. In Proc. Annual Meeting of the Association for Surgical Education (ASE), Orlando, Florida, USA, April 2013
  46. William McMahan, Ernest D. Gomez, Liting Chen, Karlin Bark, John C. Nappo, Eza I. Koch, David I Lee, Kristoffel Dumon, Noel Williams, and Katherine J. Kuchenbecker. A practical system for recording instrument interactions during live robotic surgery. In Proc. Medicine Meets Virtual Reality  2013.
Editorials, Reviews, Chapters
  1. Dumon K, Canter RJ, Williams NN.  Surgical approach to ampullary and pancreatic neoplasia.  Clinician's Guide to GI Oncology.  2004
  2. Dumon K, Darzi A, Traynor O, Williams NN.  Surgical education in the new millennium: the European Perspective.  Surgical Clinics of North America, 84:1471-1491, 2004.
  3. Dumon K, Rosato E The Pancreas. The Surgical Review. An Integrated Basic and Clinical Science Study Guide, 2005
  4. Book Review: Pioneers In Surgical Gastroenterology. Kristoffel R. Dumon, Jon B. Morris. Gastroenterology December 2007 (Vol. 133, Issue 6, Pages 2069-2070)
  5. Ronald F. Parsons, Dumon K. Central Venous Catheterization. Gowned and Gloved Surgery: introduction to common Procedures, Saunders, 2009
  6. Dumon KR, Williams NN. Adjustable gastric Banding. Evidence-based Approach to MIS, 2012.
 
Awards, Honors, and Membership in Honorary Societies
2009 Quality and Patient Safety Award:
Simulation Based Procedural Training for 2009 Medicine and Surgical Interns
 
1999 NIH Grant Recipient of a National Research Service Award (NRSA) postdoctoral fellowship grant F32 for “Development and Application of an Adenoviral Vector for FHIT Gene Transfer in Human Pancreatic Cancer"
 
1990 Erasmus Scholarship Award
 
 
 

Dr. Kristoffell Dumon

 
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