Robert C. Gorman, M.D.
Cardiovascular Surgery |
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- Profile Home
- Appointments
- Education
- Memberships
- Research
- Publications
Administrative Office:
Smilow Center for Translational Research
Gorman Cardiovascular Research Group
3400 Civic Center Blvd, Bldg 421
11th floor, Rm 113
Philadelphia, PA 19104-5156
Administrative Assistant: Nicole Caporaso
Administrative Telephone: 215-746-4085
Administrative Fax: 215-746-2375
Contact Information (internal use only)
gormanr@uphs.upenn.edu
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Robert C. Gorman, MD, is Professor of Surgery, Director of Cardiac Surgical Research and a member of the Bioengineering Graduate Group at the University of Pennsylvania. Since joining the Faculty of in 1999, Dr. Gorman has developed a research organization dedicated to the clinical translation of laboratory research into effective and less invasive clinical therapies for heart disease. His specific research interests include the pathophysiology and treatment of structural heart disease, cardiac imaging, mitral valve disease, the bicuspid aortic valve, aortic aneurysms and biocompatibility of synthetic surfaces. Dr. Gorman has been continuously funded for the past 13 years by National Institutes of Health and the American Heart Association. He has managed over 25M dollars of research funding during his career. Dr. Gorman has integrated an aggressive entrepreneurial approach to his research effort. He has 14 issued or pending patent applications which form the core intellectual property support for two start-up companies |
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| Faculty Appointments |
| 1990 - 1995 |
Assistant Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 1990 - 1995 |
Assistant Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 1995 - 1996 |
Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 1996 - 1999 |
Instructor of Cardiothoracic Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 1999 - 2005 |
Assistant Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 2005 - 2010 |
Associate Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania |
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| 2010 - present |
Professor of Surgery
Perelman School of Medicine
Philadelphia, Pennsylvania |
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| Hospital and Administrative Appointments |
| 1999 - 2010 |
Attending Surgeon
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 1999 - 2010 |
Active Surgeon
Presbyterian Medical Center Philadelphia, Pennsylvania |
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| 1999 - 2010 |
Active Surgeon, Pennsylvania Hospital
Philadelphia, Pennsylvania |
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| 1999 - 2010 |
Active Surgeon, Veterans Affairs Medical Center
Philadelphia, Pennsylvania |
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| 2003 - present |
Director of Cardiac Surgical Research |
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| Education/Training |
| 1981 - 1984 |
B.S.Ch.E.
(Chemical Engineering, Summa Cum Laude)
Newark College of Engineering,
New Jersey Institute of Technology,
Newark, New Jersey |
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| 1984 - 1985 |
Study in the Department of Bioengineering
University of Pennsylvania
Philadelphia, Pennsylvania (no degree awarded) |
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| 1985 - 1989 |
M.D. Robert Wood Johnson Medical School/
University of Medicine and Dentistry of New Jersey
Piscataway, New Jersey |
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| Postgraduate Training and Fellowship Appointments |
| 1989 - 1990 |
Intern in Surgery Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 1990 - 1992 |
Junior Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 1992 - 1994 |
Research Fellow
Harrison Department of Surgical Research
Philadelphia, Pennsylvania |
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| 1994 - 1995 |
Senior Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 1995 - 1996 |
Chief Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 1996 - 1999 |
Resident in Cardiothoracic Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| Military Service |
| 1980 - 1981 |
U.S. Naval Academy, Annapolis, MD |
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| Memberships/Societies |
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| National Societies |
- Cardiac Surgery Biology Club, 2005
- American College of Cardiology
- American Association for Thoracic Surgery, 2003
- Committee on Scientific Affairs and Government Relations (2003-2006)
- Web Committee (2003-2004)
- Society of Thoracic Surgeons, 2002
- Workforce on New Technology (2006-Present)
- Society of University Surgeons, 2001
- Membership Committee (2002-2004)
- Publications Committee (2002-2004)
- Strategic Planning Committee (2002)
- American College of Surgeons
- Fellow, 2001
- Associate Fellow, 1999- 2001
- Candidate Group, 1992-1999
- Association for Academic Surgery, 2001
- Heart Failure Society of America, 2001
- International Society for Heart and Lung Transplantation, 2000
- American Heart Association, 1999
- American Medical Association, 1985
- American Institute of Chemical Engineers, 1981-85
- American Society of Artificial Organs, 2006
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| Local Societies |
- College of Physicians of Philadelphia, Fellow, 2003-pres.
- Medical Society of New Jersey, 1985-1989
- Philadelphia County Medical Society, 1989-pres.
- Registered Engineer in Training by the State of New Jersey (#8554), 1985
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| Research |
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The research activities of Robert C. Gorman, M.D.
and Joseph H. Gorman, III, M.D. laboratory: |
| The principal goal of the Gorman Cardiovascular Research Group (GCRG) is to develop more effective and, when possible, less invasive approaches to the treatment of structural cardiovascular disease. We are committed to: |
- A better understanding of all aspects of structural cardiovascular disease.
- The design, development and commercialization of new, effective and less invasive treatment strategies for structural cardiovascular disease.
- The development and maintenance of clinically relevant large animal models of structural cardiovascular disease.
- Testing of emerging technologies developed by corporate/ academic colleagues.
- The design, development and implementation of new and novel imaging modalities that can guide emerging therapeutic technologies and allow for better clinical risk stratification for individual patients.
- The education of surgical, medical, engineering and radiology trainees at all academic levels.
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| Publications |
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| Research Publications, peer reviewed |
- Taher MF, Cecchini AB, Allen MA, Gobran SR, Gorman RC, Guthrie BL, Lingenfelter KA, Rabbany SY, Rolchigo PM, Melbin J, Noordergraaf A. Baroreceptor Responses Derived from a Fundamental Concept. Annals of Biomedical Engineering 16: 429-433, 1988
- Brolin RE, Kenler HA, Gorman RC, Cody RP. The Dilemma of Outcome of Assessment After Operations for Morbid Obesity. Surgery 105: 337-346, 1989
- Brolin RE, Gorman RC, Milgrim LM, Abbott JM, George S, Gocke DJ. Use of Nutrition Support in Patients with AIDS. A Four-Year Retrospective Review. Nutrition 7: 19-22, 1991
- Brolin RE, Gorman RC, Milgrim LM, Kenler HA. Multivitamin Prophylaxis in Prevention of Post-Gastric Bypass Vitamin and Mineral Deficiencies. International Journal of Obesity 15: 661-667, 1991
- Gorman RC, Morris JB, Metz CA, Weltz C, Mullen JL. The Button Jejunostomy for Long- Term Jejunal Feeding. A Prospective Randomized Trial. Journal of Parenteral and Enteral Nutrition 17: 428-431, 1993
- Gorman RC, Jardines L, Daly J. Enteroenteric Intussusception Due to a Metastatic Malignant Fibrous Histiocytoma. A Case Report. Journal of Surgical Oncology 54: 203-205, 1993
- Gorman RC. Atherosclerosis and Atherogenesis in Fishman S, Savage E, and Miller L eds. Review of Surgical Basic Science, JB Lippincott, Philadelphia: 124-133, 1993
- Gorman RC, Morris JB, Kaiser L. Esophageal Disease in the Elderly: Patient in Surgery in the Elderly. Surgical Clinics of North America 74: 93-112, 1994
- Gorman RC, McCaughan JS, Ratcliffe MB, Gupta KB, Guy TS, Edmunds Jr LH. A Three-Dimensional Analysis of Papillary Muscle Spatial Relationships in Acute Post Infarction Mitral Insufficiency. Surgical Forum 45: 330-334, 1994
- Gorman RC, Nance ML, Morris JB. Enteral Feeding Techniques in Torosian M, ed. Clinical Nutrition. Science and Principles of Practice, Mercel and Dekker, New York: 329-352, 1994
- Nance ML, Gorman RC, Morris JB. Techniques for Long-term Jejunal Access. Contemporary Surgery 46: 21-25, 1995
- Gorman RC, Buzby GP. Difficult Access Problems in Vascular Access in Cancer Patients. Surgical Oncology Clinics of North America 4: 453-472, 1995
- Gorman RC, McCaughan JS, Ratcliffe MB, Gupta KB, Streicher JT, Ferrari VA, St John-Sutton MG, Bogen DK, Edmunds LH Jr . Pathogenesis of Acute Ischemic Mitral Regurgitation in Three Dimensions. Journal of Thoracic and Cardiovascular Surgery 109: 684-693, 1995
- Gorman RC, Rosato, EF. Variceal Ligation and Nonshunting Procedures for Bleeding Esophageal Varices in Ernst CB and Stanley JC, ed. Current Therapy in Vascular Surgery, 3rd Edition, BC Decker, Philadelphia: 740-744, 1995
- Gorman RC, Ziats NP, Rao AK, Gikakis NS, Sun L, Khan MM, Stenach N, Sapatnekar S, Cowhand Z, Gorman III JH, Niewiarowski S, Colman RW, Anderson JM, Edmunds Jr LH Surface-Bound Heparin Fails to Reduce Thrombin Formation During Clinical Cardiopulmonary Bypass. Journal of Thoracic and Cardiovascular Surgery 111: 1-11, 1996
- Gorman III JH, Gupta KB, Streicher JT, Gorman RC, Jackson BM, Edmunds Jr LH. Dynamic 3-D Imaging of the Mitral Valve Using Rapid Sonomicrometry Array Localization. Journal of Thoracic and Cardiovascular Surgery 112: 712-725, 1996
- Gorman III JH, Gorman RC, Jackson BM, Hiramatsu Y, Gikakis NS, Kelley ST, Edmunds Jr LH. Three-dimensional Annular Changes in Acute Ischemic Mitral Regurgitation. Surgical Forum 47: 288-290, 1996
- Gorman RC, Gorman III JH, Edmunds Jr LH. Surface-Bound Heparin Fails to Reduce Thrombin Formation during Clinical Cardiopulmonary Bypass. Journal of Thoracic and Cardiovascular Surgery 112: 557, 1996
- Gorman RC, Morris JB. Minimally Invasive Access to the Gastrointestinal Tract in Rombeau JL, Rolandelli RH, Caldwell MD, ed. Clinical Nutrition Enteral and Tube Feeding, 2nd Edition, W.B. Saunders Company, Philadelphia: 125-145, 1996
- Gorman III JH, Gorman RC, Jackson BM, Hiramatsu Y, Gikakis NS, Kelley ST, St John Sutton MG, Plappert T, Edmunds Jr LH. Distortions of the Mitral Valve in Acute Ischemic Mitral Regurgitation. Annals of Thoracic Surgery 64: 1026-1031, 1997
- Gorman III JH, Gorman RC, Jackson BM, Kelley ST, Malekan R, Edmunds Jr LH. The Effect of Inotropic State on the Size of the Mitral Valve Annulus. Surgical Forum 48: 275-278, 1997
- Gorman III JH, Gorman RC, Jackson BM, Hiramatsu Y, Gikakis NS, Kelley, Edmunds Jr LH. Papillary Muscle Discoordination Rather Than Increased Annular Area Facilitates Mitral Regurgitation After Acute Posterior Infarction. Circulation 96 (Suppl II): 124-127, 1997
- Gorman RC, Rosato EF, Low DW. Total Proctocolectomy for Inflammatory Bowel Disease in Nyhus JM, Baker RJ, Fischer JE, ed. Mastery of Surgery, 3rd, Little, Brown & Co., Boston: 1481-1489, 1997
- Gorman RC, Busby GP. Perioperative Nutritional Support in Shikora SA and Blackburn GL, ed. Nutrition Support. Theory and Therapeutics, Chapman & Hall, New York: 91-112, 1997
- Gorman RC, Morris JB, Mullen JL. Enteral Access Options in Shikora SA and Blackburn GL, ed. Nutrition Support. Theory and Therapeutics, Chapman & Hall, New York: 241-270, 1997.
- Gorman III JH, Gorman RC, Plappert T, Hiramatsu Y, Gikakis NS, St. John-Sutton MG, Edmunds Jr LH. Infarct Size and Location Determine the Development of Ischemic Mitral Regurgitation. Journal of Thoracic and Cardiovascular Surgery 115: 615-622, 1998
- Brolin RE, Gorman III JH, Gorman RC, Petschenik AJ, Bradley LJ, Kenler HA, Cody RP. Are Vitamin B-12 and Folate Deficiency Clinically Important After Roux-en-Y Gastric Bypass? Journal of Gastrointestinal Surgery 2: 432-436, 1998
- Brolin RE, Gorman III JH, Gorman RC, Petschenik AJ, Robertson LB, Kenler HA, Cody RP Prophylactic Iron Supplementation After Roux-En-Y Gastric Bypass. A Prospective Double Blind Randomized Study. Archives of Surgery 133: 740-744, 1998
- Gorman RC, Lights V, Furth E, Torosian MH. Unique Presentation of a Granular Cell Tumor as a Paratracheal Mass. Oncology Reports 5: 1551-1554, 1998
- Kelley ST, Malekan R, Jackson BM, Gorman III JH, Plappert T, Gorman RC, St John Sutton MG, Edmunds Jr LH. Restraining Infarct Expansion Preserves Left Ventricular Geometry and Function After Acute Anteroapical Infarction. Circulation 99: 135-142, 1999
- Kelley ST, Malekan R, Gorman JH III, Jackson BM, Gorman RC, Suzuki Y, Plappert T, Bogen DK, St. John Sutton MG, Edmunds LH Jr. Restraining Infarct Expansion Preserves Left Ventricular Geometry and Function after Acute Anteroapical Infarction (letter) Circulation 100: e152-152, 1999
- Smythe WR, Gorman RC, DeCampli WM, Spray TL, Kaiser LR, Acker MA. Management of Exsanguinating Hemoptysis during Cardiopulmonary Bypass. Annals of Thoracic Surgery 67: 1288-1291, 1999
- Jackson BM, Gorman III JH, Gorman RC, Kelley ST, Edmunds Jr LH. Recruitment of the Non-Infarcted Borderzone Leads to Aneurysm Formation after Anteroapical Infarction. Surgical Forum 50:171-173, 1999
- Gorman RC, Gorman III JH, Jackson BM. Revascularization for Cardiogenic Shock. New England Journal of Medicine 341: 2095-2096, 1999
- Gorman RC, Gardner TJ. Myocardial Reperfusion Injury in Pillai R and Wright J, ed. Surgery for Ischemic Heart Disease, Oxford University Press, Inc., New York: 81-98, 1999
- Bridges CR, Gorman RC, Stecker MM, Bavaria JE. Acute Type A Aortic Dissection. Retrograde Cerebral Perfusion with Left Superior Vena Cava. Annals of Thoracic Surgery 69: 1940-1941, 2000
- Gorman RC, Gorman III JH. Revascularization Techniques in Acute Myocardial Infarction. New England Journal of Medicine 343: 1815-1816, 2000
- Bowen FW, Narula N, Hattori T, Plappert T, Khan M, Jackson BM, Gorman III JH, Gorman RC, St John Sutton M, Edmunds Jr LH. Late Infarct Reperfusion Attenuates Ventricular Dilatation by Affecting Collagen Remodeling in the Infarct Zone. Surgical Forum 51: 162-164, 2000
- Gorman III JH, Gorman RC, Milas BL, Acker MA. Circulatory Management in the Unstable Cardiac Patient. Seminars in Thoracic and Cardiovascular Surgery 12: 316-325, 2000
- Milas BL, Jobes DR, Gorman RC. Management of Bleeding and Coagulopathy after Heart Surgery. Seminars in Thoracic and Cardiovascular Surgery 12: 316-325, 2000
- Gorman RC, Gorman III JH. Mechanism Underlying Mechanical Dysfunction in the Borderzone Left Ventricular Aneurysm. A Finite Element Model Study. Invited commentary Annals of Thoracic Surgery 71:662, 2001
- Gorman III JH, Gorman RC, Kaiser LR. Appropriate Indications for Single and Bilateral Lung Transplantations. Current Opinion in Organ Transplantation 6:243-247, 2001
- Bavaria JE, Pochettino A, Brinster DR, Gorman RC, McGarvey ML, Gorman III JH, Escherich A, Gardner TJ. New Paradigms and Improved Results for the Surgical Treatment of Acute Type A Dissection. Annals of Surgery 234: 336-343, 2001
- Bowen FW, Carboni AF, O'Hara ML, Pochettino A, Rosengard BR, Morris RJ, Gorman RC, Gorman III JH, Acker MA. Application of "Double Bridge Mechanical" Resuscitation for Profound Cardiogenic Shock Leading to Cardiac Transplantation. Annals of Thoracic Surgery 72: 86-90, 2001
- Moainie SL, Guy TS, Jackson BM, Bowen FW, Narula J, Edmunds Jr LH, Gorman III JH, Gorman RC. Strain Induced Apoptosis of Borderzone Myocardium Leads to Heart Failure Following Antero-Apical Infarction. Surgical Forum 52: 97-99, 2001
- Guy TS, Moainie SL, Jackson BM, Bowen FW, Plappert TJ, St John Sutton M, Edmunds Jr LH, Gorman III JH, Gorman RC. Prophylactic Mitral Annuloplasty Prevents Mitral Regurgitation But Not Heart Failure After Posterolateral Myocardial Infarction. Surgical Forum 52:102-103, 2001
- Gorman III JH, Gorman RC, Morris JB. Soft Tissue Infections in Lanken PN, Manaker S, Hanson III CW, ed. The Intensive Care Manual, W.B. Saunders Company, Philadelphia: 745-753, 2001
- Bowen FW, Gorman RC. Cardiovascular Physiology in Kreisel D, Krupnick AS, Kaiser LR, ed. The Surgical Review, Lippincott, Williams & Wilkins, Philadelphia: 304-313, 2001
- Gorman RC, Kaiser LR. Lung Transplantation in Greenfield L, Lillemoe K, Mulholland M, Oldham K, Zelnock G, ed. Surgery. Scientific Principles and Practice, 3rd, Williams & Wilkins, Philadelphia: 608-632, 2001
- Gorman RC, Gorman JH III. Cellular Myoplasty: What Are We Really Trying to Achieve? Annals of Thoracic Surgery 73: 342-343, 2002
- Moainie SL, Guy TS, Plappert T, Gorman III JH, Gorman RC. Correction of Traumatic Tricuspid Regurgitation Using the Double Orifice Technique. Annals of Thoracic Surgery 73: 963-965, 2002
- Gorman RC, Gorman III JH. Cellular Myoplasty: What Are We Trying to Achieve. Journal of Thoracic and Cardiovascular Surgery 123: 582-583, 2002
- Gorman RC, Gorman III JH. The Role of Apoptosis in Myocardial Stunning After Open Heart Surgery. (Invited Commentary) Annals of Thoracic Surgery 73: 1235, 2002
- Moainie SL, Guy TS, Gorman III JH, Jackson BM, Plappert T, St John Sutton M, Edmunds Jr LH, Gorman RC. Infarct Restraint Attenuates Remodeling and Reduces Chronic Ischemic Mitral Regurgitation after Posterolateral Infarction. Annals of Thoracic Surgery 74: 444-449, 2002
- Moainie SL, Gorman JH III, Guy TS, Bowen III FW, Jackson BM, Plappert T, Narula N, St John Sutton MG, Edmunds Jr LH, Gorman RC. An Ovine Model of Postinfarction Dilated Cardiomyopathy. Annals of Thoracic Surgery 74: 753-760, 2002
- Stewart AS, Gorman RC, Pochettino A, Rosengard BR, and Acker MA. Left Ventricular Assist Device for Right Side Assistance in Patients with Transposition. Annals of Thoracic Surgery 74: 912-914, 2002
- Salgo IS, Gorman III JH, Gorman RC, Jackson BM, Bowen FW, Plappert T, Edmunds Jr LH, St John Sutton MG. Effect of Annular Shape on Leaflet Curvature in Reducing Mitral Leaflet Stress. Circulation 106: 711-717, 2002
- Jackson BM, Gorman III JH, Moainie S, Guy TS, Narula N, Narula J, St John Sutton M, Edmunds Jr LH, Gorman RC. Extension of Borderzone Myocardium in Postinfarction Dilated Cardiomyopathy. Journal of American College of Cardiology 40: 1160-1167, 2002
- Pilla JJ, Blom AS, Brockman DJ, Bowen F, Yuan Q, Giammarco J, Ferrari VA, Gorman III JH, Gorman RC, Acker MA. Ventricular Constraint Using the Acorn Cardiac Support Device Reduces Myocardial Akinetic Area in an Ovine Model of Acute Infarction Circulation 106: I207-I211, 2002
- Gorman RC, Gorman III JH. Revascularization Alone (Without Mitral Valve Repair) Suffices in Patients with Advanced Ischemic Cardiomyopathy and Mild to Moderate Mitral Regurgitation (Invited Commentary). Annals of Thoracic Surgery 74: 1481, 2002
- Bavaria JE, Brinster DR, Gorman RC, Woo YJ, Gleason T, Pochettino A. Advances in the Treatment of Acute Type A Dissection: An Integrated Approach. Annals of Thoracic Surgery 74: S1848-S1852, 2002
- Jackson BM, Gorman III JH, Salgo I, Moainie S, St John Sutton MG, Edmunds Jr LH, Gorman RC. Borderzone Geometry Increases Wall Stress after Myocardial Infarction: Contrast Echocardiographic Assessment. American Journal of Physiology (Heart and Circulatory Physiology) 284: H475-H479, 2003
- Naimark WA, Lemoore JJ, Klugherz BD, Wang Z, Guy TS, Osman H, Moainie SL, Gorman III JH, Gorman RC, Palasis M, Parmacek MS, Wilensky RL. Adenovirus-Catheter Compatibility Increases Gene Expression After Delivery to Porcine Myocardium. Human Gene Therapy 14:161-166, 2003
- Wilson EM, Moainie SL, Baskin JM, Lowry AS, Guy TS, St. John Sutton MG, Gorman III JH, Edmunds Jr LH, Gorman RC, Spinale FG. Region and Type Specific Induction of Matrix Metalloproteinases in Post Myocardial Infarction Remodeling. Circulation 107: 2857-2863, 2003
- Gorman III JH, Jackson BM, Kolansky DM, Gorman RC. Emergency Mitral Valve Replacement in the Octogenarian. Annals of Thoracic Surgery. Annals of Thoracic Surgery 76: 269-270, 2003
- Gorman III JH, Low D, Guy IV TS, Gorman RC, Rosato EF. Extended Left Colon Interposition for Esophageal Replacement Using Arterial Augmentation. Annals of Thoracic Surgery 76:933-935, 2003
- Loren AW, Desai S, Gorman RC, Schuchter LM. Re-Transplantation of a Cardiac Allograft Inadvertently Harvested from a Donor with Metastatic Melanoma. Transplantation 76:741-743, 2003
- Gorman III JH, Gorman RC, Jackson BM, Enomoto Y, St. John Sutton MG, and Edmunds Jr LH. Annuloplasty Ring Selection for Chronic Ischemic Mitral Regurgitation: Lessons from the Ovine Model. Annals of Thoracic Surgery 76:1556-1563, 2003
- Gorman RC, Gorman III JH. Does Repair of Ischemic Mitral Regurgitation Help? Annals of Thoracic Surgery. Annals of Thoracic Surgery 76:1775, 2003
- Edmunds LH Jr, Gorman JH III, Gorman RC. Sheep Models of Postinfarction Left Ventricular Remodeling in Singal PK, Dixon IMC, Kirshenbaum LA, Dhalla NS, eds. Cardiac Remodeling and Failure pp.231-244, Kluwer Academic Publishers, Boston 2003
- Gorman RC, Gorman JH III, Edmunds LH Jr. Ischemic Mitral Regurgitation in Cohn LH and Edmunds LH Jr, eds. Cardiac Surgery in the Adult pp.751-769, McGraw-Hill, New York, 2003
- Gorman III JH, Gorman RC. Semi-Rigid Annuloplasty Band Allows Dynamic Mitral Annular Motion and Minimizes Valvular Gradients: An Echocardiographic Study (Invited Commentary). Annals of Thoracic Surgery 77: 518, 2004
- Gorman III JH, Jackson BM, Enomoto Y, Gorman RC. The Effect of Regional Ischemia on Mitral Valve Annular Saddle Shape. Annals of Thoracic Surgery 77: 544-548, 2004
- Nasuti J, Zhang PJ, Feldman MD, Pasha T, Khurana JS, Gorman III JH, Gorman RC, Narula J MD, Narula N. Fibrillin and Other Matrix Proteins in Mitral Valve Prolapse Syndrome Annals of Thoracic Surgery 77: 532-536, 2004
- Guy IV TS, Moainie SL, Gorman III JH, Jackson BM, Plappert T, Enomoto Y, St. John Sutton MG, Edmunds Jr LH, Gorman RC. Prevention of Ischemic Mitral Regurgitation Does Not Influence the Outcome of Remodeling After Posterolateral Myocardial Infarction. Journal of the American College of Cardiology 43: 377-383, 2004
- Gorman III JH, Jackson BM, Moainie SL, Enomoto Y, Gorman RC. The Influence of Inotropy and Chronotropy on the Mitral Valve Sphincter Mechanism. Annals of Thoracic Surgery 77: 852-858, 2004
- Gorman RC, Jackson BM, Gorman III JH. Potential Role of Ventricular Compressive Therapy. Surgical Options in Heart Failure. Surgical Clinics of North America 84:45-59, 2004
- Gorman RC, Jackson BM, Gorman JH III, Edmunds LH Jr. The Mechanics of the Remodeled/Fibrosed Heart in Villarreal F, ed. Interstitial Fibrosis in Heart Failure, pp.149-166, Kluwer Academic Publishers, Boston 2004.
- Jackson BM, Gorman III JH, Gorman RC. Increased Border-Zone Stress in Bulging Ventricular Aneurysms. Annals of Thoracic Surgery 77: 1876, 2004
- Parish LM, Jackson BM, Enomoto Y, Gorman RC, Gorman III JH. The Dynamic Anterior Mitral Annulus. Annals of Thoracic Surgery 78:1248-1255, 2004
- Gorman RC, Gorman III JH, Parish LM, St. John-Sutton MG. Infarction Induced Ventricular Remodeling: Selected References. Annals of Thoracic Surgery 78: 1507-1510, 2004
- Dang ABC, Guccione JM, Zhang P, Gorman RC, Gorman III JH, Ratcliffe M. Effect of Ventricular Size and Patch Stiffness in Surgical Anterior Ventricular Restoration: A Finite Element Model Study. Annals of Thoracic Surgery 79:185-193, 2005
- Gorman III JH, Gorman, R C, Rosato EF. Surgical Therapy for End-Stage Achalasia. Annals of Thoracic Surgery 79: 756, 2005
- Gorman III JH, Gorman, R C. Chronic Ischemic Mitral Regurgitation: Toward a Solution or Still an Enigma? Annals of Thoracic Surgery 79: 752-753, 2005
- Enomoto Y, Gorman III JH, Moainie SL, Jackson BM, Parish LM, Plappert T, Zeeshan A, St. John-Sutton MG, Gorman RC. Early Ventricular Restraint after Myocardial Infarction: Extent of the Wrap Determines the Outcome of Remodeling. Annals of Thoracic Surgery 79:881-887, 2005
- Enomoto Y, Gorman III JH, Moainie SL, Guy TS, Jackson BM, Parish LM, Plappert T, Zeeshan A, St. John-Sutton MG, Gorman RC. Surgical Treatment of Ischemic Mitral Regurgitation May not Influence Ventricular Remodeling. Journal of Thoracic and Cardiovascular Surgery 129:504-511, 2005
- Narula N, Narula J, Zhang PJ, Haider N, Raghunath PN, Gorman III JH, Gorman RC, Tomaszewski JE. Is the Myofibrillarlytic Myocyte a Forme Fruste Apoptotic Myocyte? Annals of Thoracic Surgery 79:1333-1337, 2005
- Dang ABC, Guccione JM, Mishell JM, Zhang P, Wallace AW, Gorman RC, Gorman III JH, Ratcliffe MB. Akinetic Myocardial Infarcts Must Contain Contracting Myocytes: Finite Element Model Study. American Journal of Physiology (Heart and Circulatory Physiology) 288: H1844-H1850, 2005
- Baumgartner WA, Burrows S, del Nido PJ, Gardner TJ, Goldberg S, Gorman RC, Letsou GV, Mascette A, Michler RE, Puskas JD, Rose EA, Rosengart TK, Sellke FW, Shumway SJ, Wilke N. Special Report: Recommendations of the National Heart, Lung, and Blood Institute Working Group on Future Direction in Cardiac Surgery. Circulation 111: 3007 – 3013, 2005
- Valettas N, Gorman JH, Gorman RC. Pathophysiology and Percutaneous Coronary Sinus Repair of Mitral Regurgitation in Herrmann HC, ed. Interventional Cardiology: Percutaneous Non-Coronary Intervention, pp.49-68. Humana Press, Totawa NJ, 2005
- Blom AS, Pilla JJ, Gorman RC, Gorman III JH, Mukherjee R, Spinale FG, Acker MA. Infarct Size Reduction and Attenuation of Global Left Ventricular Remodeling with the CorCap™ Cardiac Support Device Following Acute Myocardial Infarction in Sheep. Heart Failure Reviews 10: 125-139, 2005
- Blom AS, Mukherjee R, Pilla JJ, Lowry AS, Yarbrough WM, Mingoia JT, Hendrick JW, Stroud RE, McLean JE, Affuso J. Gorman III JH, Gorman RC, Acker MA, Spinale FG. A Cardiac Support Device Modifies Left Ventricular Geometry and Myocardial Structure After Myocardial Infarction. Circulation 112:1274-1283, 2005
- Jackson BM, Parish LM, Gorman III JH, Enomoto Y, Sakamoto H, Plappert T, St. John Sutton MG, Salgo I, Gorman RC. Borderzone Geometry After Acute Myocardial Infarction: A Three-Dimensional Contrast Enhanced Echocardiographic Study. Annals of Thoracic Surgery 80:2250-2256, 2005
- Pilla JJ, Blom AS, Gorman III JH, Brockman DJ, Affuso J, Parish LM, Sakamoto H, Jackson BM, Acker MA, Gorman, RC. Early Post Infarction Ventricular Restraint Improves Borderzone Wall Thickening Dynamics during Remodeling. Annals of Thoracic Surgery 80:2257-2262, 2005
- Gorman RC, Gorman III JH. Why Should We Repair Ischemic Mitral Regurgitation? Annals of Thoracic Surgery 81: 785, 2006
- Gorman RC. Mitral Valve Surgery for CHF: A Failed Concept? Journal of the American College of Cardiology (Cardiosource Spotlight) 47:CS2-CS5, 2006
- Leshnower BG, Sakamoto H, Zeeshan A, Parish LM, Hinmon R, Plappert T, Gorman III JH, Gorman RC. The Role of Acetaminophen in Acute Myocardial Infarction. American Journal of Physiology-Heart and Circulatory Physiology. 290:2424-2431, 2006
- Kheradvar A, Milano M, Gorman RC, Gorman III JH, Gharib M. Assessment of Left Ventricular Elastic and Viscous Components Based on Ventricular Harmonic Behavior. Cardiovascular Engineering. 6: 31-40, 2006
- St. John Sutton MG, Gorman RC. Surgery for Asymptomatic Severe Mitral Regurgitation in the Elderly: Early Surgery or Wait and Watch. Circulation 114:258-260, 2006
- Sacks MS, Enomoto Y, Graybill JR, Merryman WD, Zeeshan A, Yoganathan AP, Levy R, Gorman RC, Gorman III JH. In-Vivo Dynamic Deformation of the Mitral Valve Anterior Leaflet. Annals of Thoracic Surgery 82:1369-1377, 2006
- Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman III JH, Spinale FG, Gorman RC. Expression of Matrix Metalloproteinases and Endogenous Inhibitors within Ascending Aortic Aneurysms of Patients with Marfan syndrome. Circulation 114(1 Supplement): I365-I370, 2006
- Gorman III JH, Ryan LP, Gorman RC. Pathophysiology of Ischemic Mitral Insufficiency: Does Repair Make a Difference? Heart Failure Reviews 11:219-229, 2006
- Sakamoto H, Parish L, Hamamoto H, Enomoto Y, Zeeshan A, Plappert T, Jackson B, St. John-Sutton M, Gorman RC, Gorman, III JH. The Effect of Hemodynamics on Dynamic Mitral Leaflet Curvature. Journal of Thoracic and Cardiovascular Surgery 132:1414-1419, 2006
- Gorman RC. Innovations in Valve Surgery: Introduction. Seminars in Thoracic and Cardiovascular Surgery. 18: 114, 2006
- Ryan LP, Salgo IS, Gorman RC, Gorman III JH. The Emerging Role of Three-Dimensional Echocardiography in Mitral Valve Repair. Seminars in Thoracic & Cardiovascular Surgery. 18: 126-134, 2006
- Gorman III JH, Gorman RC. Mitral Valve Surgery for CHF: A Failed Innovation? Seminars in Thoracic & Cardiovascular Surgery 18: 135-138, 2006
- Ranji M, Kanemoto S, Matsubara M, Grosso M, Gorman III J, Gorman RC, Jaggard D, Chance B. Fluorescence Spectroscopy and Imaging of Myocardial Apoptosis. Journal of Biomedical Optics 11(6), 064036; 2006
- Rapoport SH, Connolly JM, Fulmer J, Dai N, Murti BH, Gorman RC, Gorman III JH, Alferiev I, Levy RJ. Mechanisms of the In Vivo Inhibition of Calcification of Bioprosthetic Porcine Aortic Valve Cusps and Aortic Wall with Triglycidylamine/Mercapto Bisphosphonates. Biomaterials 28:690-699, 2007
- Ryan L, Jackson B, Parish L, Sakamoto H, Plappert T, St. John Sutton M, Gorman III JH, Gorman RC. Quantification and Localization of Mitral Valve Tenting in Ischemic Mitral Regurgitation Using Real-Time Dimensional Echocardiography. European Journal of Cardiothoracic Surgery 31: 840-845, 2007
- Clark-Greuel JN, Connolly JM, Sorichillo E, Narula NR, Rapport HS, Mohler ER, Gorman III JH, Gorman RC, Levy RJ Transforming Growth Factor-ß1 Mechanisms in Aortic Valve Calcification: Increased Alkaline Phosphatase and Related Events Annals of Thoracic Surgery Annals of Thoracic Surgery. 83:946-953, 2007
- Ikonomidis JS, Jones JA, Barbour JR, Stroud RE, Clark LL, Kaplan BS, Zeeshan A, Bavaria JE, Gorman III JH, Spinale FG, Gorman RC. Expression of Matrix Metalloproteinases and Endogenous Inhibitors within Ascending Aortic Aneurysms of Patients with Bicuspid or Tricuspid Aortic Valves. Journal of Thoracic and Cardiovascular Surgery 133:1028-1036, 2007
- Ryan LP, Jackson BM, Enomoto Y, Parish L, Plappert TJ, St. John-Sutton MB, Gorman RC, Gorman III JH. Description of Regional Mitral Annular Non-planarity in Healthy Human Subjects: A Novel Methodology. Journal of Thoracic and Cardiovascular Surgery 134:644-648, 2007
- Leshnower BG, Sakamoto H, Hamamoto H, Zeeshan A, Gorman III JH, Gorman RC. The Progression of Myocardial Injury during Coronary Occlusion in the Collateral Deficient Heart: A Non-Wavefront Phenomenon. American Journal of Physiology-Heart and Circulatory Physiology 293: H1799-H1804, 2007
- Ranji M, Matsubara M, Grosso MA, Jaggard DL, Chance B, Gorman RC, Gorman III JH. Fluorescence spectroscopy to assess apoptosis in myocardium. Progress in Biomedical Optics and Imaging (Proceedings of SPIE) 6438: 64380J1-64380J4, 2007
- Ryan LP, Jackson BM, Parish LM, Plappert TJ, St. John-Sutton MG, Gorman III JH, Gorman RC. Regional and Global Patterns of Annular Remodeling in Ischemic Mitral Regurgitation. Annals of Thoracic Surgery 84:553-559, 2007
- Jones JE, Stroud RE, Kaplan BS, Leone AM, Bavaria JE, Gorman III JH, Gorman RC, Ikonomidis JS. Differential Protein Kinase C Isoform Abundance in Ascending Aortic Aneurysms from Patients with Bicuspid versus Tricuspid Aortic Valves. Circulation 116: I144-I149, 2007
- Ryan LP, Jackson BM, Parish LM, Sakamoto H, Plappert TJ, St. John –Sutton M, Gorman III JH, Gorman RC. Mitral Valve Tenting Index: A Novel Assessment of Sub-Valvular Remodeling. Annals of Thoracic Surgery 84:1243-1249, 2007
- Szeto WY, Gorman RC, Gorman III JH, Acker MA. Ischemic Mitral Regurgitation. In: Cardiac Surgery in the Adult. Cohn LH (ed): McGraw-Hill, New York, pp. 785- 802, 2007
- Sacks MS, Hamamoto H, Connolly JM, Gorman RC, Gorman III JH, Levy RJ. In Vivo Biomechanical Assessment of Trigycidylamine Crosslinked Pericardium. Biomaterials 28: 5390–5398, 2007
- Ryan LP, Opotowski AR, Joseph H. Gorman III JH, Gorman RC. Management of Mitral Regurgitation in the Elderly Patient. Aging Health 3: 637-646, 2007
- Sakamoto H, Parish L, Hamamoto H, Ryan LP, Eperjesi TJ, Plappert T, Jackson BM, St John-Sutton MG, Gorman III JH, Gorman RC. The Effect of Reperfusion on Left Ventricular Regional Remodeling Strains after Myocardial Infarction. Annals of Thoracic Surgery 84:1528 –1537, 2007
- Croft LR, Gorman RC, Gorman III JH, Jimenez JH, Yoganathan AP. Efficacy of the Edge – to – Edge repair in the setting of a dilated ventricle. Annals of Thoracic Surgery 84:1578–1584, 2007
- Blom A, Pilla J, Arkles J, Dougherty L, Ryan L, Gorman III JH, Acker M, Gorman RC. Early Ventricular Restraint Prevents Infarct Expansion and Improves Borderzone Function after MI: A Study Using MRI 3D Surface Modeling and Myocardial Tagging. Annals of Thoracic Surgery 84:2004 –2010, 2007
- Jimenez JH, Liou SW, Padala M, He Z, Sacks MS, Gorman RC, Gorman III JH, Yoganathan AP. A Saddle Shaped Annulus Reduces Systolic Strain on the Central Region of the Mitral Valve Anterior Leaflet. Journal of Thoracic and Cardiovascular Surgery 134: 1562-1568, 2007
- Ryan LP, Jackson BM, Eperjesi TJ, Plappert T, St. John-Sutton M, Gorman RC, Gorman III JH. Quantitative Description of Mitral Valve Geometry by Means of Real-Time Three-Dimensional Echocardiography. Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery 2:237-244, 2007
- Atluri P, Hiesinger W, Gorman RC, Pochettino A, Jessup M, Acker MA, Morris RJ, Woo YJ. Cardiac retransplantation is an efficacious therapy for primary cardiac allograft failure. Journal Cardiothoracic Surgery 3:26-30, 2008
- Zhang PJ, Brooks JS, Goldblum JR, Yoder B, Seethala R, Pawel B, Gorman III JH, Gorman RC, Huang JH, Acker MA, Narula N. Primary cardiac sarcomas: a clinicpathologic analysis of a series with follow-up information in 17 patients and emphasis on long-term survival. Human Pathology 39: 1385-1395, 2008
- Ryan LP, Jackson BM, Hamamoto H, Eperjesi TJ, Plappert T, St. John Sutton M, Gorman RC, Gorman III JH. The Influence of Annuloplasty Ring Geometry on Mitral Leaflet Curvature. Annals of Thoracic Surgery 86: 749-760, 2008
- Ryan LP, Jackson BM, Eperjesi TJ, Plappert T, St. John Sutton M, Gorman RC, Gorman III JH. Regional Assessment of Human Mitral Leaflet Curvature Using Real-Time Three-Dimensional Echocardiography. Journal of Thoracic and Cardiovascular Surgery 136: 726-734, 2008
- Leshnower BG, Kanemoto S, Matsubara M, Sakamoto H, Hinmon R, Gorman III JH, Gorman RC. Cyclosporine Preserves Mitochondrial Morphology after Myocardial Ischemia/Reperfusion Independent of Calcineurin Inhibition. Annals of Thoracic Surgery 86:1286-1292, 2008
- Gorman III JH, Gorman RC. Surgical Therapy for Functional Mitral Regurgitation: The Key to Preventing Heart Failure? Current Heart Failure Reports 5:211-215, 2008
- Ryan LP, Matsuzaki K, Noma M, Jackson BM, Eperjesi TJ, Plappert T, St. John Sutton MG, Gorman III JH, Gorman RC. Dermal Filler Injection: A Novel Approach to Limiting Infarct Expansion. Annals of Thoracic Surgery 87: 148-156, 2009
- Kanemoto S, Matsubara M, Noma M, Leshnower BG, Parish LM, Jackson BM, Hinmon R, Hamamoto H, Gorman III JH, Gorman RC. Mild Hypothermia to Limit Myocardial Ischemia-Reperfusion Injury: Importance of Timing. Annals of Thoracic Surgery 87: 157-163, 2009
- Hamamoto H, Leshnower BG, Parish LM, Sakamoto H, Kanemoto S, Hinmon R, Miyamoto S, Gorman III JH, Gorman RC. Regional Heterogeneity of Myocardial Reperfusion Injury: Effect of Mild Hypothermia. Annals of Thoracic Surgery 87: 164-171, 2009
- Hamamoto H, Sakamoto H, Leshnower BG, Parish LM, Kanemoto S, Hinmon R, Plappert T, Miyamoto, St. John-Sutton MG, Gorman III JH, Gorman RC. Very Mild Hypothermia During Ischemia and Reperfusion Improves Postinfarction Ventricular Remodeling. Annals of Thoracic Surgery 87: 172-177, 2009
- Hamamoto H, Gorman III JH, Ryan LP, Hinmon R, Martens TP, Schuster MD, Plappert T, Kiupel M, St. John-Sutton MG, Itescu S, Gorman RC. Allogeneic Mesenchymal Precursor Cell Therapy to Limit Post-MI Remodeling: The Effect of Cell Dosage. Annals of Thoracic Surgery 87: 794-802, 2009
- Pilla JJ, Gorman III JH, Gorman RC. Theoretical Impact of Infarct Compliance on Left Ventricular Function. Annals of Thoracic Surgery 87: 803-811, 2009
- Parish LM, Gorman III JH, Kahn S, Plappert T, St. John-Sutton MG, Bavaria JE, Gorman RC. Aortic Size in Acute Type A Dissection: Implications for Preventive Ascending Aortic Replacement. European Journal of Cardiothoracic Surgery 35: 941-946, 2009
- Ranji M, Matsubura M, Leshnower BG, Hinmon R, Jaggard DL, Chance B, Gorman RC, Gorman III JH. Quantifying Acute Myocardial Injury Using Ratiometric Fluorometry. IEEE-Transactions on Biomedical Engineering 56:1556-1563, 2009
- Phillippi JA, Klyachko EA, Kenny IV JP, Eskay MA, Gorman RC, Gleason TG. Basal and Oxidative Stress-Induced Expression of Metallothionein is Decreased in Ascending Aortic Aneurysms of Bicuspid Aortic Valve Patients. Circulation. 119:2498-2506, 2009
- Eckert CE, Vergnat M, Gorman III JH, Gorman RC, Sacks MS. In-Vivo Dynamic Deformation of the Mitral Annulus. Annals of Biomedical Engineering. 37: 1757-1771, 2009
- Connolly JM, Bakay MA, Fulmer JT, Gorman RC, Gorman III JH, Oyama MA, Levy RJ. Fenfluramine Disrupts the Mitral Valve Interstitial Cell Response to Serotonin. American Journal of Pathology. 175:988-997, 2009
- Pilop C, Aregger F, Gorman RC, Brunishol R, Gerrits B, Schaffner T, Gorman III JH, Matyas G, Carrel T, Frey BM. Proteomic Analysis in Aortic Media of Patients with Marfan Syndrome Reveals Increased Activity of Calpain 2 in Aortic Aneurysms. Circulation. 120:983-991, 2009
- Liu Y, Wen H, Gorman RC, Pilla JJ, Gorman III JH, Buckberg GD, Teague SD, Kassab GS. Reconstruction of Myocardial Tissue Motion and Strain Fields from Displacement-Encoded MR Imaging. American Journal of Physiology. 297: H1151-H1162, 2009
- Dixon JA, Gorman RC, Stroud RE, Bouges S, Hirotsugu H, Gorman III JH, Martens TP, Itescu S, Schuster MD, Plappert T, John-Sutton MG, Spinale FG. Mesenchymal Cell Transplantation and Myocardial Remodeling Following Myocardial Infarction. Circulation 120:S220–S229, 2009
- Padala M, Hutchison RA, Croft LR, Jimenez JH, Gorman RC, Gorman III JH, Sacks MS, Yoganathan AP. Saddle Shape of the Mitral Annulus Reduces Systolic Strain on the P2 Segment of the Posterior Mitral Leaflet. Annals of Thoracic Surgery. Annals of Thoracic Surgery 88:1499-1505, 2009
- Mahmood F, Subramanian B, Gorman III JH, Gorman RC, Levine RA, Maslow A, Panzica PJ, Hagberg RM, Karthik S, Khabbaz KR. Three-Dimensional Echocardiographic Assessment of Changes in Mitral Valve Geometry after Valve Repair. Annals of Thoracic Surgery 88:1838–1844, 2009
- Xu C, Pilla JJ, Blom AS, Isaac G, Gorman III JH, Gorman RC, Dougherty L. Myocardial Deformation Analysis of 3D Tagged Cardiac Images Using an Optical Flow Method. Journal of Cardiovascular Magnetic Resonance 12:19, 2010
- Matsubara M, Ranji M, Leshnower BG, Noma M, Ratcliffe SJ, Chance B, Gorman RC, Gorman III JH. In Vivo Fluorometric Assessment of Cyclosporine on Mitochondrial Function during Myocardial Ischemia and Reperfusion. Annals of Thoracic 89:1532-1537, 2010
- Bouma W, Noma M, Kanemoto S, Matsubara M, Leshnower BG, Hinmon R, Gorman III JH, Gorman RC. Gender-Related Resistance to Myocardial Ischemia-Reperfusion Injury is Associated with High Constitutive ARC Expression. American Journal of Physiology 298: H1510-H1517, 2010
- Herdrich BJ, Gorman RC. Progenitor Cells for the Treatment of Acute Myocardial Infarction. Advances in Wound Care 1: 519-525, 2010
- Ifkovits JL, Tous E, Minakawa M, Morita M, Robb JD, Koomalsingh KJ, Gorman III JH, Gorman RC, Burdick JA. Injectable Hydrogel Properties Influence Extent of Post-Infarction Left Ventricular Remodeling in an Ovine Model. Proceedings of the National Academy of Science 107: 11507-11512, 2010.
- Matsuzaki K, Morita M, Hamamoto H, Noma M, Robb JD, Gillespie MJ, Gorman III JH, Gorman RC. Annuloplasty for Ischemic Mitral Regurgitation does not Influence Long-Term Ventricular Remodeling. Annals of Thoracic 90:788-795, 2010.
- Mahmood F, Gorman III JH, Subramanian B, Gorman RC, Panzica PJ, Hagberg RM, Lerner AB, Maslow A, Khabbaz KR. Changes in Mitral Valve Annular Geometry After Repair Saddle Shaped vs. Flat Annuloplasty Rings. Annals of Thoracic Surgery 90:1212-1220, 2010.
- Witschey WR, Pilla JJ, Ferrari G, Koomalsingh KJ, Harris M, Hinmon R, Zsido GA, Gorman III JH, Gorman RC, Reddy R. Rotating Frame Spin Lattice Relaxation In a Swine Model of Chronic Left Ventricular Myocardial Infarction. Magnetic Resonance in Medicine 64: 1454-1461, 2010.
- Herdrich BJ, Noma M, Danzer E, Davey MG, Lind RC, Plappert T, Radu A, Gorman III JH, Gorman RC, Liechty KW. Regenerative Healing Following Fetal Myocardial Infarction. European Journal of Cardiothoracic Surgery 38: 691-698, 2010.
- Xu C, Brinster CJ, Jassar AS, Vergnat M, Eperjesi TJ, Gorman RC, Gorman III JH, Jackson BM. A Novel Approach to in Vivo Mitral Valve Stress Analysis. American Journal of Physiology American Journal of Physiology 299: H1790-H1794, 2010.
- Matsubara M, Kanemoto S, Leshnower BG, Albone EF, Hinmon R, Plappert T, Gorman III JH, Gorman RC. Single Dose GLP-1-Tf Ameliorates Myocardial Ischemia/Reperfusion Injury. Journal of Surgical Research 165:38-45, 2011.
- Vergnat M, Jassar AS, Jackson BM, Ryan LP, Eperjesi TJ, Pouch AM, Weiss SJ, Cheung AT, Acker MA, Gorman III JH, Gorman RC. Ischemic Mitral Regurgitation: A Quantitative Three-Dimensional Echocardiographic Analysis. Annals of Thoracic Surgery 91:157-164, 2011.
- Jassar AS, Brinster CR, Vergnat V, Robb JD, Eperjesi TJ, Pouch AM, Weiss SJ, Cheung AT, Acker MA, Gorman III JH, Gorman RC, Jackson BM. Quantitative Mitral Valve Modeling using Real-Time 3D-Echocardiography –Technique and Repeatability. Annals of Thoracic Surgery 91:165-171, 2011.
- Jackson BJ, Gorman RC. Invited Commentary on Three-Dimensional Echocardiography for the Preoperative Assessment of Patients with Left Ventricular Aneurysm. Annals of Thoracic Surgery 91:113–22, 2011.
- Nathan DP, Xu C, Gorman III JH, Fairman RM, Bavaria JE, Gorman RC, Chandran KB Jackson BM. Pathogenesis of Acute Aortic Dissection: A Finite Element Stress Analysis. Annals of Thoracic 91:458-464, 2011.
- Gorman RC, Jackson BM, Burdick JA, Gorman III JH. Infarct Restraint to Limit Adverse Ventricular Remodeling. Journal of Cardiovascular Translational Research 4:73–81, 2011.
- Jermihov PN, Lu J, Sacks MS, Gorman RC, Gorman III JH, Chandran KB. Effect of Geometry on the Leaflet Stresses in Simulated Models of Congenital Bicuspid Aortic Valves. Cardiovascular Engineering and Technology 2: 48-56, 2011.
- Robb JD, Harris MA, Minakawa M, Rodriguez E, Koomalsingh KJ, Shuto T, Jassar AS, Allukian M, Shin D, Dori Y, Glatz AC, Rome JJ, Gorman RC, Gorman III JH, Gillespie MJ. Bilateral Branch Pulmonary Artery Melody® Valve Implantation Reduces Pulmonary Regurgitation in an Ovine Model of Postoperative Tetralogy of Fallot. Circulation: Cardiovascular Interventions 4: 80-87, 2011.
- Ekhterae D, Hinmon R, Matsuzaki K, Noma Mio, Zhu W, Xiao RP, Gorman RC, Gorman III JH. Infarction Induced Myocardial Apoptosis and ARC Activation. Journal of Surgical Research 166: 59-67, 2011.
- Gorman RC, Gillespie MJ, Gorman III JH. Percutaneous Repair or Surgery for Mitral Regurgitation. New England Journal of Medicine 365:189, 2011.
- Morita M, Eckert CE, Matsuzaki K, Noma Mio, Ryan LP, Burdick JA, Jackson BM, Gorman III JH, Sacks MS, Gorman RC. Modification of Infarct Material Properties Limits Adverse Ventricular Remodeling. Annals of Thoracic Surgery 92:617-625, 2011.
- Vergnat M, Jackson BM, Cheung AT, Weiss SJ, Ratcliffe SJ, Gillespie MJ, Woo YJ, Bavaria JE, Acker MA, Gorman RC, Gorman III JH. Saddle-Shape Annuloplasty Increases Mitral Leaflet Coaptation after Repair for Flail Posterior Leaflet. Annals of Thoracic Surgery 92:797– 804, 2011.
- Connolly JM, Bakay MA, Alferiev IS, Gorman RC, Gorman III JH, Kruth HS, Ashworth PE, Kutty JK, Schoen FJ, Bianco RW, Levy RJ. Triglycidylamine Cross-linking Combined with Ethanol Inhibits Bioprosthetic Heart Valve Calcification. Annals of Thoracic Surgery 92: 858–865, 2011.
- Wenk JF, Eslami P, Zhang Z, Xu C, Gorman III JH, Robb JD, Ratcliffe MB, Gorman RC, Guccione JM. A Novel Method for Quantifying the In-Vivo Mechanical Effect of Material Injected into a Myocardial Infarction. Annals of Thoracic Surgery 92:935-941, 2011.
- Gorman RC, Gorman III JH. A Clinical Commentary: Injectable Acellular Hydrogels for Cardiac Repair. Journal of Translational Cardiovascular Research 4:543-544, 2011.
- Dixon JA, Gorman RC, Stroud RE, Meyer EC, Baker NL, Morita M, Hamamoto H, Ryan LP, Gorman III JH, Spinale FG. Targeted Regional Injection of Biocomposite Microspheres Alters Post Myocardial Infarction Remodeling and Matrix Proteolytic Pathways. Circulation 124:S35-S45, 2011.
- Nathan DP , Xu C, Plappert T, Desjardins B, Gorman III JH, Bavaria JE, Gorman RC, Chandran KB, Jackson BM. Increased Ascending Aortic Wall Stress in Patients with Bicuspid Aortic Valves. Annals of Thoracic Surgery 92:1384-1390, 2011.
- Nathan DP, Xu Chun, Pouch AM, Chandran KB, Desjardins B, Gorman III JH, Fairman RM, Gorman RC, Jackson BM. Increased Wall Stress of Saccular versus Fusiform Aneurysms of the Descending Thoracic Aorta. Annals of Vascular Surgery 25: 1129-1137, 2011.
- Robb JD, Minakawa M, Koomalsingh KJ, Shuto T, Jassar AS, Jackson BM, Ratcliffe SJ, Gorman RC, Gorman III JH. Posterior Leaflet Augmentation Improves Leaflet Tethering in Repair of Ischemic Mitral Regurgitation. European Journal of Cardiothoracic Surgery 40: 1501-1507, 2011.
- Tous E, Ifkovits JL, Koomalsingh KJ, Shuto T, Kondo N, Gorman III JH, Gorman RC, Burdick JA. Injectable Hyaluronic Acid Hydrogel Degradation Behavior on Infarction Induced Ventricular Remodeling. Biomacromolecules 12:4127-4135, 2011.
- Shuto T, Kondo N, Dori Y, Koomalsingh KJ, Glatz AC, Rome JJ, Gorman III JH, Gorman RC, Gillespie MJ. Percutaneous Transvenous Melody® Valve-in-Ring Procedure for Mitral Valve Replacement. Journal of the American College of Cardiology 58: 2475-2480, 2011.
- Jones JA, Stroud RE, O’Quinn EC, Black LE, Barth JL, Elefteriades JA, Bavaria JE, Gorman III JH, Gorman RC, Spinale FG, Ikonomidis JS. Selective Micro-rna Suppression in Human Thoracic Aneurysms: Relationship of mir-29a to Aortic Size and Proteolytic Induction. Circulation: Cardiovascular Genetics 4:605-613, 2011.
- Alturi P, Gorman RC, Gorman III JH, Acker MA. Ischemic Mitral Regurgitation. In: Cardiac Surgery in the Adult. Cohn LH (ed): McGraw-Hill, New York, pp. 629-646, 2012.
- Ikonomidis JS, Ruddy JM, Benton SM, Arroyo J, Brinsa TA, Stroud RE, Zeeshan A, Bavaria JE, Gorman III JH, Gorman RC, Spinale FG, Jones JA. Aortic Dilatation With Bicuspid Aortic Valves: Cusp Fusion Correlates to Matrix Metalloproteinases and Inhibitors Annals of Thoracic Surgery 93:457-464, 2012.
- Jassar AS, Bavaria JE, Szeto WY, Moeller PJ, Maniaci J, Milewski RK, Gorman III JH, Desai ND, Gorman RC, Pochettino A. Graft Selection for Aortic Root Replacement in Complex Active Endocarditis: Does It Matter? Annals of Thoracic Surgery 93:480-487, 2012.
- Pouch AM, Xu C, Yushkevich PA, Jassar AS, Vergnat M, Gorman III JH, Gorman RC, Sehgal CM, Jackson BM. Semi-Automated Mitral Valve Morphometry and Computational Stress Analysis Using 3D Ultrasound. Journal of Biomechanics 45:903-907, 2012.
- Pouch AM, Yushkevich PA, Jackson BM, Jassar AS, Vergnat M, Gorman III JH, Gorman RC, Sehgal CM. Development of a Semi-Automated Method for Mitral Valve Modeling with Medial Axis Representation Using 3D Ultrasound. Medical Physics 39:933-950, 2012.
- Kondo N, Shuto T, McGarvey JR, Koomalsingh KJ, Takebe M, Gorman RC, Gorman III JH, Gillespie MJ. Transvenous Melody® Valve-In-Ring Procedure for Mitral Valve Replacement: Feasibility in Four Distinct Annuloplasty Rings. Annals of Thoracic Surgery 93:783-788, 2012.
- Gorman III JH, Gorman RC. Impact of Annuloplasty Device Aggressiveness on Leaflet Coaptation (Reply). Annals of Thoracic Surgery 93:1021, 2012.
- Sainger R, Grau JB, Branchetti E, Poggio P, Seefried WF, Field BC, Acker MA, Gorman RC, Gorman III JH, Hargrove III CW, Bavaria JE, Ferrari G. Human Myxomatous Mitral Valve Prolapse: Role of Bone Morphogenetic Protein 4 in Valvular Interstitial Cell Activation. Journal of Cellular Physiology 227: 2595-2604, 2012.
- Sainger R, Grau JB, Poggio P, Branchetti E, Bavaria JE, Gorman RC, Gorman III JH, Ferrari G. Dephosphorylation of Circulating Human Osteopontin Correlates with Severe Valvular Calcification in Patients with Calcific Aortic Valve Disease. Biomarkers 17:111-118, 2012.
- Robb JD, Harris MA, Minakawa M, Rodríguez E, Koomalsingh KJ, Shuto T, Dori Y, Gorman RC, Gorman III JH, Gillespie MJ. An Ovine Model of Pulmonary Insufficiency and Right Ventricular Outflow Tract Dilatation. Journal of Heart Valve Disease 21:247-252, 2012.
- Pouch AM, Yushkevich PA, Jackson BM, Gorman III JH, Gorman III JH , Gorman RC, Sehgal CM. Dynamic Shape Modeling of the Mitral Valve from Real-Time 3D Ultrasound Images Using Continuous Medial Representation. Progress in Biomedical Optics and Imaging (Proceedings of SPIE) 8320: 8320091-8320098, 2012.
- Xu C, Jassar AS, Nathan DP, Eperjesi TJ, Brinster CJ, Vergnat M, Gorman RC, Gorman III JH, Jackson BM. Augmented Mitral Valve Leaflet Area Decreases Leaflet Stress: A Finite Element Simulation. Annals of Thoracic Surgery 93: 1141-1145, 2012.
- Wenk JF, Klepach D, Lee LC, Zhang Z, Ge L, Tseng E, Martin A, Kozerke S, Gorman III JH, Gorman RC, Guccione JM. First Evidence of Depressed Contractility in the Borderzone of a Human Myocardial Infarction. Annals of Thoracic Surgery 93: 1188-1193, 2012.
- Siefert AW, Jimenez JH, West DS, Koomalsingh KJ, Gorman RC, Gorman III JH, Yoganathan AP. In-Vivo Transducer to Measure Dynamic Mitral Annular Forces. Journal of Biomechanics 45: 1514-1516, 2012.
- Kloner RA, Hale S, Dai W, Gorman RC, Shuto T, Koomalsingh KJ, Sloan RC, Fraiser CR, Watson CR, Bostian PA, Kypson AP Brown DA. Reduction of Ischemia/Reperfusion Injury with Bendavia, a Mitochondrial-Targeting Cytoprotective Peptide. Journal of the American Heart Association 1:e001644, 2012.
- Siefert AW, Jimenez JH, Koomalsingh KJ, West DJ, Aguel F, Shuto T, Gorman RC, Gorman III JH, Yoganathan AP. Dynamic Assessment of Mitral Annular Force Profile in an Ovine Model. Annals of Thoracic Surgery 94:59-65, 2012.
- Tous E, Weber HM, Lee LH, Koomalsingh KJ, Takashi S, Kondo N, Gorman III JH, Lee D, Gorman RC, Burdick JA. Tunable Hydrogel-Microsphere Composites that Modulate Local Inflammation and Collagen Bulking. Acta Biomaterialia 8:3218-3227, 2012.
- Vergnat M, Levack MM, Jassar AS, Jackson BM, Acker MA, Woo YJ, Gorman RC, Gorman III JH. The Influence of Saddle-Shaped Annuloplasty on Leaflet Curvature in Patients with Ischemic Mitral Regurgitation. European Journal of Cardiothoracic Surgery 42:493-499, 2012.
- Witschey WRT, Zsido GA, Koomalsingh KJ, Kondo N, Minakawa M, Shuto T, McGarvey JR, Levack MM, Contijoch F, Pilla JJ, Gorman III JH, Gorman RC. In Vivo Chronic Myocardial Infarction Characterization by Spin Locked Cardiovascular Magnetic Resonance. Journal of Cardiovascular Magnetic Resonance 14:37, 2012.
- Amini R, Eckert CE, Koomalsingh KJ, Minakawa M, Gorman III JH, Gorman RC, Sacks MS. On the In-Vivo Deformation of the Mitral Valve Anterior Leaflet: Effects of Annular Geometry and Referential Configuration. Annals of Biomedical Engineering 40: 1455-1467, 2012.
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