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John C. Kucharczuk, M.D.
Thoracic Surgery

 
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Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
6 White Building
Philadelphia, Pennsylvania 19104
Administrative Assistant: Katie Chance and Melissa Thompson
Administrative Phone: 215-615-1792
Administrative Fax: 215-615-6562
Patient Appointments: 215-615-LUNG

Clinical Office:
Perelman Center for Advanced Medicine
Penn Lung Center
West Pavilion, 1st floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Assistant: Katie Chance
Clinical Phone: 215-662-4988

Contact Information (internal use only)

john.kucharczuk@uphs.upenn.edu

 

Dr. Kucharczuk is the Chief of the Division of Thoracic Surgery. He completed medical school, a general surgery residency and thoracic surgery training all at the University of Pennsylvania. His clinical and research interests focus on general thoracic surgery. He has expertise in the diagnosis and treatment of benign and malignant diseases of the chest including lung cancer, esophageal cancer, mesothelioma, and mediastinal tumors. He performs a high volume of thoracic surgical cases at the Hospital of the University of Pennsylvania, is an active member of the thoracic oncology research laboratory, serves as the educational coordinator for the thoracic surgery service and is involved in a number of basic as well clinical research projects.

 
Faculty Appointments
2009 - present Associate Professor of Surgery at HUP, PPMC and PAH
Perelman School of Medicine
Philadelphia, Pennsylvania
 
2001 - 2009 Assistant Professor of Surgery at HUP, PPMC and PAH
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1998 - 2001 Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1996 - 1998 Assistant Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1994 - 1996 Research Fellow
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1992 - 1994 Assistant Instructor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
Hospital and Administrative Appointments
2012 - present Chief, Division of Thoracic Surgery
University of Pennsylvania Health System
 
2011 - 2012 Interim Chief, Division of Thoracic Surgery
University of Pennsylvania Health System
 
2009 - present

Medical Director Ravdin 6, Thoracic Surgical Unit
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

 
2001 - present Active Surgeon, Pennsylvania Hospital
Philadelphia, Pennsylvania
 
2001 - present Active Surgeon, Presbyterian Medical Center
Philadelphia, Pennsylvania
 
2001 - present Attending Surgeon
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2005 - 2009 Medical Director, Rhoads 1 Thoracic Surgery Unit
Hospital of the University of Pennsylvania
 
2001 - 2006 Chief, Thoracic Surgery Section
Philadelphia Veterans Administration Hospital
Philadelphia, Pennsylvania
 
2001 - 2006 Active Surgeon, Veterans Affairs Medical Center
Philadelphia, Pennsylvania
 
Other Appointments
2011 - 2014  Executive Committee General Thoracic Surgical Club
 
2011 - 2014 Society of Thoracic Surgeons Workforce on National Databases
 
2010 - present American Board of Thoracic Surgery General Thoracic Subcommittee Exam Consultant
 
2008 - present Society of Thoracic Surgery General Thoracic Surgery Database Task Force
 
2007 - present Society of Thoracic Surgery Task Force on Quality Initiatives.
 
2007 - present American Joint Council on Cancer (AJCC). Worldwide Esophageal Cancer Collaboration/ Esophageal Staging Task Force.
 
2007 - present Society of Thoracic Surgeons General Thoracic Surgery Outcomes measures Representative to the American Quality Alliance and the National Quality Forum.
 
2007 - present Appointment to the Society of Thoracic Surgeons Task Force on Quality Initiatives
 
2000 - 2001

Resident Representative
Residency Review Committee in Thoracic Surgery
American Council for Graduate Medical Educatio

 
2000 - 2001 American Board of Medical Specialties
America Council on Graduate Medical Education Joint Initiative on Resident Evaluation – Thoracic Surgery Resident Representative
 
Education/Training
1988 - 1992 M.D. University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1987 - 1988 Georgetown University - College of Arts and Science
Washington, DC
 
1983 - 1987

B.C.E. Villanova University
College of Engineering, Villanova, Pennsylvania
(Cum Laude, Chemical Engineering)

 
Post-Graduate Training
1999 - 2001 Resident in Cardiothoracic Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1998 - 1999 Chief Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1996 - 1998 Resident in Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1994 - 1996 Research Training Fellowship
Thoracic Oncology Research Laboratory
Harrison Department of Surgical Research
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
1993 - 1994 Junior Resident in General Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1992 - 1993 Intern in General Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
Memberships/Societies
 
National and International Societies
  • American College of Surgeons (Fellow)
  • Society of Thoracic Surgeons
  • Association of Academic Surgeons
  • General Thoracic Surgery Biology Club
  • General Thoracic Surgical Club
Local Societies
  • Pennsylvania Medical Society
Membership In Scientific Committees
  • National Institutes of Health Study Section Reviewer
    • ZRG1 SSMI 10B:  Bioengineering and Physiology.
    • ZGR SSMI 50R:  Bioengineering and Nanotechnology
  • American Joint Council on Cancer (AJCC) Worldwide Esophageal
    • Cancer Collaboration/Esophageal Staging Task Force
 
Research
 
Research Interests
2008 - 2013 A Multi-center, Randomized, Double-blind, Placebo-controlled, Phase 3 Study of Single-agent Tarceva® (erlotinib) Following Complete Tumor Resection with or without Adjuvant Chemotherapy in Patients with Stage IB-IIIA Non-small Cell Lung Carcinoma who have EGFR-positive Tumors
 
2008 - 2010 Isolation and Characterization of Lung Cancer Stem Cells
 
2006 - 2011 A Randomized Phase III Study of Sublobar Resection versus Subblolbar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC) 3cm. or Smaller: Z4032
 
2004 - 2010 Use of Proteomic Analysis of Serum Samples for Detection of Non-Small Cell Lung Cancer: Z4031
 
2003 - 2009 A Prospective Study of the Prognostic Significance of Occult Metastases in Patients with Resectable Non-Small Cell Lung Carcinoma
 
2002 - 2010 Randomized Trial of Mediastinal Lymph Node Sampling vs. Complete Lymphadenectomy During Pulmonary Resection in the Patient with NO or N1 (Less Than Hilar) Non-Small Cell Carcinoma
 
2007 - 2012 A double-blind, randomized, placebo-controlled Phase III study to assess the efficacy of recMAGE-A3 + AS15 Antigen-Specific Cancer Immunotherapeutic as adjuvant therapy in patients with resectable MAGE-A3-positive non-small cell lung cancer.
 
2006 - 2013 A Randomized, Double-blind Study to Evaluate the Safety and Effectiveness of the Exhale® Drug-Eluting Stent in Homogeneous Emphysema Subjects with Severe Hyperinflation
 
2003 - 2005 Respiratory muscle adaptations to COPD, VA hospital Philadelphia. Stars and Strips Pilot Grant.
 
2001 - 2002 The use of functional genomic technology (micro arrays) to improve the ability to diagnose malignant mesothelioma. McCabe Fellow, University of Pennsylvania school of Medicine.
 
1994 - 1996 Therapeutic approaches and development of animal models for the treatment of thoracic malignancies utilizing gene therapy, antisense oligonucleotides, and immunotherapeutic approaches. Advisor: Larry R. Kaiser, M.D., Thoracic Oncology Research Laboratory-Division of Thoracic Surgery, University of Pennsylvania Medical Center.
 
1994 - 1996 Pre-clinical toxicity studies of intrathoracic recombinant adenoviral gene therapy utilizing the HSV-thymidine kinase gene in rodents and non-human primates. Proposal to the Food and Drug Administration for a Phase I clinical trial. Advisor: Steven M. Albelda, M.D., Thoracic Oncology Research Laboratory-Division of Pulmonary and Critical Care Medicine, University of Pennsylvania Medical Center.
 
1986 Development and evaluation of a centrifugal extraction system to remove inhibitors from production grade monomer products. Rohm and Haas Company Research and Development Campus, Springhouse, Pennsylvania.
 
Publications
 
Research Publications, Peer-Reviewed
  1. Hwang HC, Smythe WR, Elshami AA, Kucharczuk JC, Amin KM, Williams JL, Litzky LA, Kaiser LR, Albelda SM. Gene therapy using adenovirus carrying the herpes simplex-thy-midine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer.  Am J Respir Cell Mol Biol. 1995 Jul;13(1):7-16.
  2. Kucharczuk JC, Elshami AA, Zhang HB, Smythe WR, Hwang HC, Tomlinson JS, Amin KM, Litzky LA, Albelda SM, Kaiser LR. Pleural-based mesothelioma in immune competent rats:  A model to study adenoviral gene transfer.  Ann Thorac Surg. 1995 Sep;60(3):593-597; discussion 597-8.
  3. Elshami AA, Kucharczuk JC, Sterman DH, Smythe WR, Hwang HC, Amin KM, Litzky LA, Albelda SM, Kaiser LR. The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg. 1995 Sep;222(3):298-307; 307-310.
  4. Elshami AA, Kucharczuk JC, Zhang HB, Smythe WR, Litzky LA, Hwang HC, Kaiser LR, Albelda SM. Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the herpes simplex thymidine kinase gene.  Hum Gene Ther. 1996 Jan 20;7(2):141-148.
  5. Elshami AA, Saavedra A, Zhang HB, Kucharczuk JC, Spray DC, Fishman GI, Kaiser LR, Albelda SM. Gap junctions play a role in the ‘bystander effect’ of the herpes simplex virus thymidine kinase/ganciclovir system in vitro.  Gene Ther. 1996 Jan;3(1):85-92.
  6. Randazzo BP, Kucharczuk JC, Litzky LA, Brown SM, MacLean A, Kaiser LR, Fraser NW, Albelda SM. Herpes simplex 1716--an ICP 34.5 mutant--is severely replication restricted in human skin xenografts in vivo.  Virology. 1996 Sep 15;223(2):392-395.
  7. Kucharczuk JC, Raper S, Elshami AA, Amin KM, Sterman DH, Wheeldon EB, Wilson JM, Litzky LA, Kaiser LR, Albelda SM:  Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates. Hum Gene Ther. 1996 Dec 1;7(18):2225-33.
  8. Kucharczuk JC, Randazzo B, Chang MY, Amin KM, Elshami AA, Sterman DH, Rizk NP, Molnar-Kimber KL, Brown SM, MacLean AR, Litzky LA, Fraser NW, Albelda SM, Kaiser LR. Use of a “replication-restricted” herpes virus to treat experimental human malignant mesothelioma.   Cancer Res. 1997 Feb 1;57(3):466-71.
  9. Kucharczuk JC, Cohen MI, Rhodes LA, Karl TR, Spray TL, Gaynor JW. Epicardial atrial pacemaker lead placement after multiple cardiac operations. Ann Thorac Surg. 2001 Jun;71(6):2057-8.
  10. Deeb ME, Brinster CJ, Kucharczuk J, Shrager JB, Kaiser LR.  Expanded indications for transcervical thymectomy in the management of anterior mediastinal masses.  Ann Thorac Surg. 2001 Jul;72(1):208-11.
  11. Marshall MB, Deeb ME, Bleier JL, Kucharczuk JC, Friedberg JS, Kaiser LR, Shrager JB.  Suction vs water seal after pulmonary resection: a randomized prospective study.  Chest. 2002 Mar;121(3): 831-5.
  12. Shrager JB, Deeb MB, Mick R, Brinster CJ, Childers HE, Marshall MB, Kucharczuk JC, Galetta SL, Bird SJ, Kaiser LR. Transcervical thymectomy for myasthenia gravis achieves results comparable to thymectomy by sternotomy. Ann Thorac Surg. 2002 Aug;74(2):320-6; discussion 326-7.
  13. Singhal S, Weiwrodt R, Malden LD, Amin KM, Matzie K, Friedberg J, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM.  Gene expression profiling of malign-nant mesothelioma.  Clin Cancer Res. 2003 Aug 1;9(8):3080-97.
  14. Singhal S, Amin KM, Kruklitis R, Marshall MB, Kucharczuk JC, DeLong P, Litzky LA, Kaiser LR, Albelda SM.  Differentially expressed apoptotic genes in early stage lung adenocarcinoma predicted by expression profiling. Cancer Biol Ther. 2003 Sep-Oct; 2(5):566-71.
  15. Kucharczuk JC, Kaiser LR, Marshall MB. Weerda diverticuloscope:  novel use to remove embedded esophageal foreign bodies.  Ann Thorac Surg. 2003 Oct;76(4):1276-8.
  16. Paulson EC, Singhal S, Kucharczuk JC, Sterman DH, Kaiser LR, Marshall MB.  Bronchial sleeve resection for posttransplant stricture. Ann Thorac Surg. 2003 Dec; 76(6):2075-6.
  17. Brinster CJ, Singhal S, Lee L, Marshall MB, Kaiser LR, Kucharczuk JC.  Evolving options in the management of esophageal perforation.  Ann Thorac Surg. 2004 Apr; 77(4):1475-83. Review.
  18. Marshall MB, Kaiser LR, Kucharczuk JC.  Simple technique for maximal thoracic muscle harvest.  Ann Thorac Surg. 2004 Apr;77(4):1465-6.
  19. Ahmed Z, Marshall MB, Kucharczuk JC, Kaiser LR, Shrager JB.  Lung cancer in trans-plant recipients: a single-institution experience.  Arch Surg. 2004 Aug;139(8):902-6.
  20. Marshall MB, Ahmed Z, Kucharczuk JC, Kaiser LR, Shrager JB.  Catamenial pneumo-thorax: optimal hormonal and surgical management.  Eur J Cardiothorac Surg. 2005 Apr; 27(4):662-6.
  21. Lee LS, Nance M, Kaiser LR, Kucharczuk JC.  Familial massive leiomyoma with esophageal leiomyomatosis:  an unusual presentation in a father and his 2 daughters.  J Pediatr Surg. 2005 May;40(5):e29-32.
  22. Kucharczuk JC, Kaiser LR.  Radical lobectomy, esophagectomy, and mediastinal dissections for intrathoracic malignancy.  Surg Oncol Clin N Am. 2005 Jul; 14(3):499-509, vi.
  23. O'Brien PK, Kucharczuk JC, Marshall MB, Friedberg JS, Chen Z, Kaiser LR, Shrager JB.  Comparative study of subxiphoid versus video-thoracoscopic pericardial "window". Ann Thorac Surg. Dec 2005 80(6):2013-19.
  24. Marshall MB, Kucharczuk JC, Shrager JB, Kaiser LR.  Anterior surgical approaches to the thoracic outlet. J Thorac Cardiovasc Surg. 2006 Jun;131(6):1255-60.
  25. Levine S, Nguyen T, Friscia M, Zhu J, Szeto W, Kucharczuk JC, Tikunov  BA, Rubinstein NA, Kaiser LR, Shrager JB.  Parasternal Intercostal muscle remodeling in severe chronic obstructive pulmonary disease. J Appl Physiol. 2006 Nov;101(5):1297-302.  Epub 2006 Jun 15.
  26. Kreider ME, Hansen-Flaschen J, Ahmad NN, Rossman MD, Kaiser LR, Kucharczuk JC, Shrager JB.  Complications of video-assisted thoracoscopic lung biopsy in patients with interstitial lung disease.  Ann Thoracic Surg. 2007 Mar; 83(3):1140-4.
  27. Willmont AS, Levine MS, Rubesin SE, Kucharczuk JC, Laufer I.  Intraluminal migration of surgical drains after transhiatal esophagogastrectomy: radiographic findings and clinical relevance.  AJR Am J Roentgenol. 2007 Oct;189(4):780-5.
  28. Vachani A, Nebozhyn M, Singhal S, Alila L, Wakeam E, Muschel R, Powell CA, Gaffney P, Singh B, Brose MS, Litzky LA, Kucharczuk J, Kaiser LR, Marron JS, Showe MK, Albelda SM, Showe LC.  A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma. Clin Canc Res. 2007  May 15;13(10):2905-15.
  29. Ra J, Paulson EC, Kucharczuk J, Armstrong K, Wirtalla C, Rapaport-Kelz R, Kaiser LR, Spitz FR.  Postoperative mortality after esophagectomy for cancer: development of a preoperative risk prediction model.  Ann Surg Oncol. 2008 Jun;15(6):1577-84. Epub 2008 Apr 1.
  30. Wright CD, Kucharczuk JC, O’Brien SM, Grab JD, Allen MS; Society of Thoracic Surgeons General Thoracic Surgery Database.  Predictors of major morbidity and mortality after esophgectomoy for esophageal cancer:  a Society of Thoracic Surgeons General Thoracic Surgery Database risk adjustment model.  J Thorac Cardiovasc Surg. 2009 Mar;137(3):587-95; discussion 596.
  31. Kucharczuk JC.  Invited Commentary.  Hybrid techniques for the management of acute esophageal perforations.  Ann Thorac Surg. 2009 Jul;88(1):199.
  32. Showe MK, Vachani A, Kossenkov AV, Yousef M, Nichols C, Nikonova EV, Chang C, Kucharczuk J, Tran B, Wakeam E, Yie TA, Speicher D, Rom WN, Albelda S, Showe LC.  Gene expression profiles in peripheral blood mononuclear cells can distinguish patients with non-small cell lung cancer from patients with nonmalignant lung disease. Cancer Res. 2009 Dec 15;69(24):9202-10. Epub.
  33. Itkin M, Kucharczuk JC, Kwak A, Trerotola SO, Kaiser LR. Nonoperative thoracic duct embolization for traumatic thoracic duct leak: experience in 109 patients. J Thorac Cardiovasc Surg. 2010 Mar;139(3):584-89; discussion 589-90. Epub 2009 Dec 29.
  34. Montone KT, Litzky LA, Feldman MD, Peterman H, Mathis B, Baliff J, Kaiser LR, Kucharczuk J, Nachamkin I.  In situ hybridization for Coccidioides immitis 5.8S ribosomal RNA sequences in formalin-fixed, paraffin-embedded pulmonary specimens using a locked nucleic acid probe:  a rapid means for identification in tissue sections. Diagn Mol Pathol. 2010 Jun;19(2):99-104.
  35. Weiss J, Eaby B, Stevenson J, Kucharczuk J, Cooper J, Kaiser L, Shrager J, Rengan R, Lancer C, Evans T.  Adjuvant cisplatin and docetaxel for non-small cell lung cancer:  the Hospital of the University of Pennsylvania experience.  J Thorac Oncol. 2010 May; 5(5):667-72.
  36. Koo CW, Miller WT, Kucharczuk JCFocal ground-glass opacities in non-small cell lung carcinoma resection patients.  Eur J Radiol.2010 Jul 29.[Epub ahead of print]
  37. Sanchez PG, Kucharczuk JC, Su S, Kaiser LR, Cooper JD.  National Emphysema Treatment Trial redux:  accentuating the positive.  J Thorac Cardiovasc Surg. 2010 Sep; 140(3):564-72.
  38. Gillespie CT, Sterman DH, Cerfolio RJ, Nader D, Mulligan MS, Mularski RA, Musani AI, Kucharczuk JC, Gonzalez HX, Springmeyer SC. Endobronchial valve treatment for prolonged air leaks of the lung: a case series. Ann Thorac Surg. 2011 Jan;91(1):270-3
  39. Berman AT, Litzky L, Livolsi V, Singhal S, Kucharczuk JC, Cooper JD, Friedberg JR, Evans TL, Stevenson JP, Metz JM, Hahn SM, Rengan R. Adjuvant radiotherapy for completely resected stage 2 thymoma. Cancer. 2011 Feb 1. doi: 10.1002/cncr.25851. Epub 2011 Feb 1.
  40. Levine S, Biswas C, Dierov J, Barsotti R, Shrager JB, Nguyen T, Sonnad S, Kucharczuk JC, Kaiser LR, Singhal S, Budak MT.  Increased proteolysis, myosin depletion, and atrophic AKT-FOXO signaling in human diaphragm disuse.  Am J Respir Crit Care Med. 2011 Feb 15;183(4):483-90.  Epub 2010 Sep 10.
  41. Predina JD, Puc MM, Bergey MR, Sonnad SS, Kucharczuk JC, Staddon A, Kaiser LR, Shrager JB.  Improved survival after pulmonary metastasectomy for soft tissue sarcoma.  J Thorac Oncol. 2011 May;6(5):913-9.
  42. Shah PL, Slebos DJ, Cardosa PF, Cetti E, Voelker K, Levine B, Russell ME, Goldin J, Brown M, Cooper JD, Sybrecht GW; EASE trial study group. Bronchoscopic lung-volume reduction with Exhale airway stents for emphysema (EASE trial): randomized, sham-controlled, multicentre trial. Lancet. 2011 Sep 10;378(9795):997-1005.
  43. Fernandes AT, Mitra N, Xanthopoulos E, Evans T, Stevenson J, Langer C, Kucharczuk JC, Lin L, Rengan R.  The Impact of Extent and Location of Mediastinal Lymph Node Involvement on Survival in Stage III Non-Small-Cell Lung Cancer Patients Treated with Definitive Radiotherapy. Int J Radiat Oncol Biol Phys. 2011 Nov 19 [Epub ahead of print].
  44. Kucharczuk JC. Chest wall sarcomas and induction therapy. Thorac Surg Clin. 2012 Feb;22(1):77-81. Epub 2011 Oct 13.
  45. Patnaik SK, Yendamuri S, Kannisto E, Kucharczuk JC, Singhal S, Vachani A.  MicroRNA Expression Profiles of Whole Blood in Lung Adenocarcinoma.  PLoS One 2012; 7 (9) :e46045. Epub 2012 Sept 28
  46. Trister AD, Pryma DA, Xanthopoulos E, Kucharczuk JC, Sterman D, Rengan R.  Prognostic Value of Primary Tumor FDG Uptake for Occult Mediastinal Lymph Node Involvement in Critically N2/N3 Node-negative Non-Small Cell Lung Cancer.  American Journal of Clinical Oncology.  2012 Oct 29. [Epub ahead of print].
Reviews in Peer-Reviewed Research Publications
  1. Lee LS, Singhal S, Brinster CJ, Marshall B, Kochman ML, Kaiser LR, Kucharczuk JC.  Current management of esophageal leiomyoma. J Am Coll Surg. 2004 Jan;198(1):136-46. Review.
  2. Kucharczuk JC.  Radiofrequency ablation: Emerging therapy for the small pulmonary nodule? Semin Thorac Cardiovasc Surg. 2005 Summer;17(2):134-7. Review.
Abstracts
  1. Singhal S, Lee L, Brinster C, Friedberg J, Amin KA, Kucharczuk JC, Johnson SW, Sterman D, Kaiser LR, Albelda SM. “Genomic Profiling to Explain Positive PET-18FDG Imaging in Patients with Malignant Pleural Mesothelioma.” American Association of Surgery. 36th Annual Meeting. Novermber 7, 2002.
  2. Singhal S, Weiwrodt R, Malden, L, Matzie K, Friedberg J, Amin KM, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” American College of Surgeons.88th Annual Meeting. San Francisco, California. October 9, 2002.
  3. Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” University of Pennsylvania 8th Annual Respiration Research Retreat. Germantown, PA. June 21, 2002.
  4. Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” University of Pennsylvania Department of Medicine Research Retreat. Philadelphia, PA. May 15, 2002.
  5. Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” The Eunice and Irving Annual Scientific Symposium: Advances in Cancer Research. Philadelphia, PA. March 26, 2002.
  6. Kucharczuk JC, Marshall MB, Singhal S, Shrager JB, Kaiser LK.  Needlescopic Sympathectomy for Palmar Hyperhidrosis.  The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting.  Miami FL, October 16-20, 2002.
  7. Kruklitis R, Singhal S, Greenberg J, Marshall MB, Shrager JB, Sterman DH, Kaiser LR, Kucharczuk JC.  Endobronchial Surgery for Removal of Endobronchial Hamartomas.  The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting.  Miami FL, October 16-20, 2002
  8. Marshall MB, Kucharczuk JC, Shrager JB, Kaiser LR.  Anterior Transcervical Thoracic Approach for NSCLC:  Lessons Learned.  The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting.  Miami FL, October 16-20, 2002
  9. Singhal S, Kucharczuk JC, Marshall MB, Kruklitis RJ, Friscia M, Shrager JB, Albleda SM, Kaiser LR.  Transcriptional Profiling of Malignant Mesothelioma Using cDNA Microarrays.  The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting.  Miami FL, October 16-20, 2002.
  10. Singhal S, Kucharczuk JC, Marshall MB, Albelda SM, Kaiser LR. Transcript profiling of patients with N0 lung adenocarcinomas to predict survival.  83rd Annual Meeting of the American Association for Thoracic Surgery, Boston, MA, May 4-7, 2003.
  11. Singhal S, Kruklitis, RJ, Marshall MB, Kucharczuk JC, Albelda SM, Kaiser LR.  Viral gene transfer of IL-12 prolongs survival and prevents recurrence in early and advanced non-small cell lung cancer.  Surgical Forum of the American College of Surgeons, 2003.
  12. Ahmed Z, Marshall MB, Kucharczuk JC, Kaiser LR, Shrager JB.  Bronchogenic Carcinoma in immunosupressed transplant recipients.  Presented at the Surgical Forum of the American College of Surgeons, 2003.
  13. Kreider ME, Ahmad NN, Hansen-Flaschen JC, Kaiser LR, Brinster C, Kucharczuk JC, Shrager JB.  Complications of thoracoscopic lung biopsy in patients with interstitial lung disease.  Presented at the American College of Chest Physicians Meeting, Montreal, Canada, Nov. 2005.
  14. Shrager JB, Nathan DP, Spence AM, Kurichi JE, Kucharczuk JC, Kaiser LR. Compara-tive study of anterior and posterior approaches to pancoast tumors at a single institution.  Presented at the American Association for Thoracic Surgery, Philadelphia, PA, May 2006.
  15. Kucharczuk JC, Shrager JB, Kaiser LR, Cooper JD.  Transcervical Thymectomy for Non Thymomatous Myasthenia Gravis.  Society of Thoracic Surgery.  January 2007, San Diego CA.
  16. Kucharczuk JC, Cooper JD.  Tracheal resection for subglotic stenosis.  Presented at the General Thoracic Surgical Club 25th Annual Meeting, Captiva Island, FL, Feb 15, 2007.
  17. Cornelius, K, Abbott, P, Moore B, Murphy J, Kucharczuk JC.  Lobectomy for lung cancer in the octogenarian; is age a risk factor?  A single institutional general thoracic database review.  Presented at the Society of Thoracic Surgeons Advances in Quality and Outcomes Meeting, Minneapolis, MN, Nov. 1-3, 2007.
  18. Kucharczuk JC, Shrager JB, Kaiser LR, Cooper JD.  Tracheal Resection with Primary Reconstruction for subglottic stricture following tracheostomy.  Presented at the 44th Annual Society of Thoracic Surgeons Meeting, Fort Lauderdale, FL, Jan. 29, 2007.
  19. Paulson EC, Ra J, Wirtalla C, Rohrbach J, Kelz R, Cooper J, Rosato E, Gorman J,  Kaiser L, Kucharczuk JC, Spitz F.  Predictors of postoperative course following esophagectomy at a high volume institution.  Presented at the Academic Surgical Congress, Huntington Beach, CA, Feb. 15, 2008.
  20. Wright CD, Allen MS, Grab JD, Kucharczuk JC: Predictors of Major Morbidity and Mortality after Esophagectomy for Esophageal Cancer: An STS General Thoracic Surgery Database Risk Adjustment Model. Plenary Session, American Association for Thoracic Surgery 88th  Annual Meeting, San Diego, CA. May 12, 2008.
  21. Kucharczuk JC, SU S, Cooper JD.  Resection of Giant Right Epiphrenic Diverticulum and Hiatal Repair via a Belsey Wrap.  22nd Annual Meeting of The General Thoracic Surgical Club.  St. Petersburg Florida.  March 13, 2009.
  22. Sanchez PG, Kucharczuk JC, Su S, Kaiser LR, Cooper JD.  NETT Redux (Accentuating the Positive).  Simultaneous Scientific Session.  American Association for Thoracic Surgery 89th Annual Meeting, Boston Mass, May 11, 2009.
  23. Itkin M, Kucharczuk JC, Trerotola S, Kwak A, Cope C, Kaiser LR.  Non Operative Thoracic Duct Embolization for traumatic Chylothorax:  Experience in 103 patients.  Accepted for Presentation:  Plenary Session, American Association for Thoracic Surgery 89th Annual Meeting, Boston Mass, May 12, 2009.
  24. A. Berman, S. Singhal, S. Su, Kucharczuk JC, J. Cooper, J. Shrager, L. Kaiser,  J. Friedberg, J. Faerber, T. Evans, J. Stevenson, C.J. Langer, J. Metz, E. Glatstein, S.M. Hahn, R. Rengan: Adjuvant Radiotherapy for Completely Resected Stage II Thymoma. International Association for the study of Lung Cancer.  13th World Conference on Lung Cancer.  San Francisco CA, July 31, 2009.
  25. A. Trister, C. Gillespie, A. Haas, D. Sterman, Kucharczuk JC, J. Cooper, J. Friedberg, J. Wobb, T. Lucas, D. Pryma, C. Divgi, L. Lin, R. Rengan : Prognostic Value of Primary Tumor FDG Uptake for Occult Mediastinal Lymph Node Involvement in N2 Node Negative Non Small Cell Lung Cancer as Staged by Positron Emission Tomography. International Association for the study of Lung Cancer.  13th World Conference on Lung Cancer.  San Francisco CA, July 31, 2009.
  26. R. Rengan, R. Mick, L. Lin, A. Maity, A. Gupta, T. Evans, J. Stevenson, C.J. Langer MD, Kucharczuk JC, J. Friedberg, S. Prendergast, J. Driesbaugh, and S.M. Hahn: Early Results of a Phase I Trial of the HIV Protease Inhibitor Nelfinavir with Concurrent Chemoradiotherapy (CT-RT) for Stage IIIA/IIIB NSCLC. International Association for the study of Lung Cancer.  13th World Conference on Lung Cancer.  San Francisco CA, July 31, 2009.
  27. Weiss J, Evans T, Eaby B, Stevenson J, Kucharczuk J, Cooper J , Kaiser L, Shrager J, Rengan R, Langer C. Adjuvant Cisplatin and Docetaxel (CDDP-Doc) for Non small cell Lung Cancer (NSCLC): the Hospital of the University of Pennsylvania (HUP) Experience. 13th World Conference on Lung Cancer.  San Francisco CA, July 31, 2009.
Editorials, Chapters & Participation in Committee Reports
  1. Buzby GP, Kucharczuk JC.  Changes in immunologic function.  In: Fischer JE (ed).  Nutrition and Metabolism in the Surgical Patient, Second Edition.  Boston: Little, Brown & Co., 1995, 623-635.
  2. Kucharczuk JC, Kaiser LR.  Invited Review:  Literature review in video-assisted thoracic surgery.  Contemporary Surgery, Nov. 2002.
  3. Kucharczuk JC.  Cancer of the lung from molecular biology to treatment guidelines. In: Weitberg AB (ed). Human Pathology, 33(4):451, Apr. 2002.
  4. Kucharczuk JC.  Invited book review: Thoracic surgical oncology: Exposures & tech-niques (Nesbit JG & Wind GG, eds).  Annals of Thoracic Surgery 77(1):167, Jan. 2004.
  5. Kucharczuk JC, Kaiser LR.  Radical lobectomy, esophagectomy and mediastinal dissections for intra thoracic malignancy.  Surgical Clinics of North America:  The Evolutions of Radical Cancer Surgery in Oncology.  14(3):499-509, July 2005.
  6. Kucharczuk JC, Shrager JB.  Anterior mediastinal masses.  In: Sellke F, Swanson S, del Nido P (eds). Sabiston & Spencer: Surgery of the Chest, Seventh Edition.   New York: Elsevier, 2005, 667-680.
  7. Kucharczuk JC.  Surgical approaches to esophageal neoplasms. In: Kochman M (ed). The Clinician's Guide to Gastrointestinal Oncology.  Thorofare, NJ: SLACK Incorporated Professional Book Division, 2005, 11-22.
  8. Kucharczuk JC, Kaiser LR.  Esophageal tumors and injury.  Greenfield’s Surgery:  Scientific Principles & Practice, 4th Edition.  Greenfield, LJ (ed).  Philadelphia:  Lippincott Williams & Wilkins, 2006, 691-708.
  9. Kucharczuk JC, Kaiser LR.  Bronchoscopy.  Chap. 7 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds).  London: Oxford University Press, 2006, 63-72.
  10. Kucharczuk JC.  The pericardium.  Chap. 29 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds).  London: Oxford University Press, 2006, 307-314.
  11. Kucharczuk JC, Kaiser LR.  Extrapleural pneumonectomy. Chap. 30 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds). London: Oxford University Press, 2006, 315-324.
  12. Kucharczuk JC.  Chest wall resection.  Mastery of Cardiothoracic Surgery, 2nd Edition.  Kaiser LR, Kron IL, Spray TL (eds.).  Philadelphia: Lippincott Williams & Wilkins, 2007, 222-227.
  13. Kucharczuk JC, Kaiser LR.  Surgical techniques: Surgery of pectus deformities.    Chap. 108 in Pearson’s Thoracic Surgery 3rd Edition. Philadelphia:  Churchill Livingstone, 2007, 1329-1339.
  14. Kucharczuk JC, Cooper JD.  Transcervical thymectomy for non thymomatous myasthenia gravis.  Chap. 141 In Pearson’s Thoracic Surgery 3rd Edition.  Philadelphia: Churchill Livingstone, 2007, 1715-1719.
  15. Kucharczuk, JC.  ACP XXI: Disorders of the mediastinum and hila.  American College of Physicians Medicine. WebMD Inc, 2008.
  16. Kucharczuk JC.  Diagnostic Procedures in Thoracic Surgery.  Sugical Pitfalls. Elsevier, November 2008
  17. Rascoe P, Kucharczuk JC, Cooper JD.  Surgery of the Mediastinum Historical Notes.    Thoracic Surgical Clinics. Volume 19 (1), February 2009
  18. Kucharczuk JC, Cooper JD.  Surgical technique: Transcervical thymectomy.  Chapt. 134 in Adult Chest Surgery. New York: McGraw Hill, 2009, 1115-1120.
  19. Rascoe P, Kucharczuk JC, Kaiser LR.  Esophageal tumors and injury.  Greenfield’s  Surgery:  Scientific Principles and Practice. 5th Edition.  Greenfield, LJ (ed).  2010
  20. Friscia M, Kucharczuk JC.  The Esophagus.  The Surgical Review 3rd edition.  Lippincott Williams & Wilkins, 2010, 98-109.
  21. Chung H, Kucharczuk JC, Shrager JB.  Anterior mediastinal masses.  Sabiston & Spencer:  Surgery of the Chest, 8th Edition.  New York: Elsevier, 2010, 633-644.
  22. Myers BF, Kucharczuk JC, Cooper JD.  Surgery for Emphysema, Sabiston & Spencer:  Surgery of the Chest, 8th t Edition.  New York: Elsevier, 2010, 195-206.
  23. Kucharczuk JC.  Kaiser, LR.  Surgical Management of Metastatic Lung Disease.  Principles and Practice of Surgical Oncology.  Lippincott Williams & Wilkins.  Philadelphia, 2010, 938-949.
  24. Friscia M, Kucharczuk JC.  The Esophagus.  The Surgical Review.  An Integrated Basic and Clinical Science Study Guide.  Lippincott Williams & Wiklins, 2010, 98-109.
  25. Rascoe P, Kucharczuk JC, Kaiser LR.  Esophageal cancer in the elderly patient. In:  Rosenthal RA, Zenilman ME, Katlic MR (eds). Principles and Practice of Geriatric Surgery, 2nd Edition.  New York: Springer, 2011, 747-761.
  26. Rascoe P, Kucharczuk JC, Malignant Esophgeal Disease in the Elderly. Cardiothoracic Surgery in the Elderly.  edited by Marc Katlic and Zenilman.  Springer, NY. 2011.
  27. Kucharczuk JC.  The Role of VATS Pleurodesis in the Treatment of Primary Spontaneous Pneumothorax.  Difficult Decisions in Thoracic Surgery.  An Evidence Based Approach.  Springer, NY. 2011.
Alternative Media
  1. Kucharczuk JC.  Review, Pier on line Project, American College of Physicians-American Society of Internal Medicine, Pneumothorax Module 2002.
  2. Kucharczuk JC.  TissueLink resection of metastatic renal cell to the lung with en-bloc chest wall resection.  (multimedia presentation) www.Tissuelink.com.
  3. Kucharczuk JC.  Surgical management of lung abscess.  Thoracic Surgery Directors Online Requisite Curriculum Publication http://www.tsda.org/curriculum/entry.htm, July 2003.
  4. Kucharczuk JC.  Congenital lung abnormalities module:  Pulmonary sequestration.  Multimedia Presentation.  Thoracic Surgery Directors Requisite Online Curriculum Publication. http://www.tsda.org/curriculum/entry.htm, July 2003.
  5. Kucharczuk JC, Kaiser LR.  Resection of symptomatic, complex aspergilloma.
    Available at: http://www.ctsnet.org/doc/8793. Posted Feb. 9, 2004.
  6. Kucharczuk JC.  2: Chest Wall Mass, 4: Thorax. ACS Surgery Online.  Souba WW, Fink MP, Jurkovich, GJ et al, Eds.  WebMD Inc., New York 2005 http://www.acssurgery/ Oct. 2005.
  7. Kucharczuk JC.  American College of Surgeon’s Weekly Curriculum:  Apr. 5, 2006 -- Chest Wall Mass, http://www.acssurgery.com/acsw, The ACS Surgery Weekly Curriculum, 111 Eighth Avenue, Suite 700, New York, NY 10011, Posted Apr. 5, 2006.
Patents
  1. Kucharczuk JC.  Application No.09/117,218 USPTO: Treatment of Non-Neuronal Cancer Using HSV Mutant (Application under review).
 
Awards, Honors and Membership In Honorary Societies
1996 Jonathan E. Rhoads Research Award
 
1996 The William Y. Inouye Award for excellence in teaching by a Surgical Resident
 
1995 Resident Essay Competition; Pennsylvania Association for Thoracic Surgery
 
1991 Elected to Alpha Omega Alpha
 
1987 Elected to Phi Kappa Phi
 
1987 Dean’s Award for Academic Achievement, College of Engineering, Villanova University
 
1986 Elected to Sigma Xi, The Scientific Research Society
 
1985 Elected to Tau Beta Phi, Engineering Honor Society
 
1983 Lehigh Valley Scholar Athlete Award

Dr. John Kucharczuk

 
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