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Matthew H. Levine, M.D., Ph.D.
Transplant Surgery

 
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Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
1 Founders Building
Philadelphia, PA 19104
Adminitrative Assistant: Tiffini Sykes
Administrative Telephone: 215-662-7367
Administrative Fax: 215-615-4900

Clinical Office:
Perelman Center for Advanced Medicine
West Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Telephone: 215-662-7367
Clinical Fax: 215-615-4900

Contact Information (internal use only)

matthew.h.levine@uphs.upenn.edu

 

Matthew Levine, MD, PhD, attended Brown University, followed by a combined MD/PhD at Yale.  He completed his PhD in immunobiology in the laboratory of Charles Janeway Jr., with work focusing on the discovery of positive selection events in the peripheral development of B cells. He then went on to complete general surgery residency at the Massachusetts General Hospital and a fellowship in abdominal organ transplantation at the University of California, San Francisco. He joined the faculty at the University of Pennsylvania in 2009 in the Division of Transplantation. He is clinically active in liver and kidney transplantation in adults and children, pancreas transplantation, and laparoscopic kidney donation.

Dr. Levine’s basic science research is focused on defining the role that histone deactylases (HDACs) and heat shock proteins (hsps) play in tolerance of renal ischemia-reperfusion, work that is now funded by the NIH.  This work has demonstrated significant renal function protection via HDAC inhibition by drug and by gene knockout which has also been associated with substantial diminution of fibrosis after injury.  Further work is investigating which specific HDAC pathways are involved and determining if the site of action is on the kidney or the inflammatory cascade.  Additional directions of this work are defining the role that hsps play in renal ischemic damage and whether the expression of hsps is beneficial or detrimental to renal ischemic recovery.  Additional work is investigating the role of gender and hormone milieu on the response to renal ischemic injury.  Dr. Levine has additional collaborative basic science studies investigating the role of costimulation blockade and cytokine pathway manipulation in rejection or tolerance of limb transplantation in murine models, work that is being initiated with funding from the Department of Defense and is initiated in collaboration with Dr Wayne Hancock and Dr Scott Levin. Additional collaborative work with the Hancock  laboratory involves the effects of typical immunosuppression strategies on human regulatory T cells (Treg) after transplantation.  He is active in clinical research as well, with projects pertaining to liver transplantation for hepatocellular carcinoma and efficacy and utility of renal transplantation in certain clinical scenarios, particularly pediatric transplantation. He is a national committee member of the American Society of Transplant Surgeons and the Association for Academic Surgery and a member of the Society of University Surgeons.

 
Faculty Appointments
2009 - present Assistant Professor of Surgery
Perelman School of Medicine
Philadelphia, Pennsylvania
 
2007 - 2008 Instructor of Surgery
University of California at San Francisco
San Francisco, California
 
Hospital and Administrative Appointments
2009 - present Attending Surgeon
Children’s Hospital of Philadelphia
Philadelphia, Pennsylvania
 
2009 - present Attending Surgeon
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
2006 - 2006 Locum Tenens Attending in General Surgery
Kaiser Permanente Health System
San Francisco, California
 
Education/Training
1994 - 2001 Ph.D. Yale University School of Medicine
New Haven, Connecticut (Immunobiology)
 
1994 - 2001 M.D. Yale University School of Medicine
New Haven, Connecticut
 
1990 - 1994 B.S. Brown University
Providence, Rhode Island (Biochemistry)
 
Postgraduate Training and Fellowship Appointments
2007 - 2008

Fellowship, Abdominal Organ Transplantation
University of California Medical Center
San Francisco, California

 
2002 - 2006 Resident in Surgery, Massachusetts General Hospital
Boston, Massachusetts
 
2001 - 2002 Intern in Surgery, Massachusetts General Hospital
Boston, Massachusetts
 
Memberships/Societies
 
National/International Societies
2013 - present  The Society of University Surgeons (SUS)
 
2012 - present

The Transplantation Society (TTS)

 
2010 - present  Association for Academic Surgery (AAS)
       AAS Leadership Committee Member, 2012-present
 
2010 - present  American Society of Transplantation (AST)
 
2010 - present  American Association for the Study of Liver Diseases (AASLD)
 
2009 - present International Liver Transplantation Society (ILTS)
 
2007 - present American Society of Transplant Surgeons (ASTS)
       Candidate Member, 2007-2011
       Full Member, 2011-present
       CME Committee Member, 2010-present
           Co-Chair 2013-2016
 
2005 - present 

American College of Surgeons (ACS)
       Candidate Member, 2005-2011
       Fellow, 2011-present (FACS)

 

Local/Regional Societies

2011 - present 

ACS, Greater Philadelphia Chapter, Member

 
Scientific Committees
2010 - present

Member and Co-Chair, CME Committee
American Society of Transplant Surgeons (ASTS)

 
2010 - present

Association for Academic Surgery (AAS)
       Committee, 2012-present

 
Research
 
Dr. Levine's research interests are:
  • Regulatory T cells and transplantation
  • Chromatin regulation of regulatory T cell function by histone acetylation/deacetylation
  • Hepatocellular carcinoma in liver transplantation
    Recovery of renal dysfunction after liver transplantation
 
 
 
 
 
Publications
 
Research Publications, Peer Reviewed
  1. Levine MH, Haberman AM, Sant’Angelo DB, Hannum LG, Shlomchik MJ, Janeway CA.  Peripheral selection of BCR repertoire in heavy chain transgenic mice.  Scandinavian Journal of Immunology 50:C11, July 1999.
  2. Levine MH, Haberman AM, Sant’Angelo DB, Hannum LG, Cancro MP, Janeway CA, Shlomchik MJ.  A B-cell receptor-specific selection step governs immature to mature B cell differentiation.   Proceedings of the National Academy of Science, USA 97:2743-2748, Mar. 14, 2000.
  3. He X, Janeway CA Jr, Levine M, Robinson E, Preston-Hurlburt P, Viret C, Bottomly K. Dual receptor T cells extend the immune repertoire for foreign antigens.  Nature Immunology 3:127-134, Feb. 2002.
  4. Porrett P, Kamoun M, Parson R, Bloom R, Goral S, Reese P, Grossman R, Baluarte J, Bleicher M, Doyle A, Markmann J, Levine M, Barker C, Olthoff K, Naji A, Shaked A, Abt P.  Kidney transplantation at the University of Pennsylvania 1998-2008.  Clinical Transplantation 143-152, 2009. PMID 20527069.
  5. Cassuto J, Reese P, Sonnad S, Bloom R, Levine M, Naji A, Abt P, Olthoff K, Shaked A. Wait list death and survival benefit of kidney transplantation among nonrenal transplant recipients. American Journal of Transplantation 10(11):2502-2511, Nov. 2010.  PMID 20977641.
  6. Levine MH, Parekh J, Feng S, Freise C.  Kidney transplant performed after liver transplant: A single center experience. Clinical Transplantation 25(6):915-920, Nov./Dec. 2011. PMID 21077957.
  7. Hsu J, Reese P, Naji A, Levine M, Abt P.  Increased early graft failure in right-sided living donor nephrectomy. Transplantation 91(1):108-114, Jan. 2011.  PMID 21441855.
  8. Levine MH.  Transplant tolerance and regulatory T cells: Let's get into specifics. Journal of Surgical Research 176(1):17-19,  July 2012. PMID 21696771.
  9. Akimova T, Beier U, Wang L, Levine MH, Hancock W.  Helios expression is a marker of T cell activation and proliferation.  PLoS ONE 6(8):e24226, Aug 2011. PMID 21918685.
  10. Redfield R, Parsons R, Rodriguez E, Mustafa M, Cassuto J, Vivek K, Noorchashm H, Naji A, Levine M, Abt P.  Underutilization of A2 ABO incompatible kidney transplantation.  Clinical Transplantation 26(3):289-294, May 2012. PMID 22032287.
  11. Cassuto J, Levine MH, Reese P, Bloom R, Goral S, Naji A, Abt P.  The influence of induction therapy for kidney transplantation after a non-renal transplant. Clinical Journal of American Society of Nephrology (CJASN) 7(1):158-166, Jan. 2012. PMID 22076872.
  12. Porrett P, Levine MH.  Fever and suprapubic tenderness ten days after kidney transplant-tation.  American Journal of Transplantation 12(1):254-256, Jan. 2012.  PMID 22244125.
  13. Levine MH, Reese P, Wood A, Baluarte H, Huverserian A, Naji A, Abt P.  Inferior allograft outcomes in adolescent recipients of renal transplants from ideal deceased donors.  Annals of Surgery 255(3):556-564, Mar. 2012. PMID 22330037.
  14. Enestvedt K, Levine MH: Abdominal Pain, Fever, and Free Air One Year Post Simultaneous Pancreas Kidney Transplant. American Journal of Transplantation 12(6): 1657-9, Jun 2012. PMID 22642475.
  15. Ruebner R, Goldberg D, Abt PL, Bahirwani R, Levine M, Sawinski D, Shults J, Bloom RD, Reese PP:  Risk of End-Stage Renal Disease Among Liver Transplant Recipients with Pre-Transplant Chronic Kidney Disease.  American Journal of Transplantation 12(11): 2958-65. Nov 2012. PMID 22759237.
  16. Akimova T, Kamath BM, Goebel JW, Meyers KE, Rand EB, Hawkins A, Levine MH, Bucuvalas JC, Hancock WW.  Differing effects of rapamycin or calcineurin inhibitor on T-regulatory cells in pediatric liver and kidney transplant recipients.  American Journal of Transplantation12(12): 3449-61.  Dec 2012. PMID: 22994804.
  17. Parzych EM, Li H, Yin X, Liu Q, Wu TL, Podsakoff GM, High KA, Levine MH, Ertl HCJ. Effects of Immunosuppression on Circulating AAV Capsid-Specific T cells in Humans.  Human Gene Therapy 24(4): 431-42.  Apr 2013.  PMID: 23461589.
  18. Wolf JH, Sulewski ME, Cassuto JR, Levine MH, Naji A, Olthoff KM, Shaked A, Abt PL.  Simultaneous thoracic and abdominal transplantation: can we justify two organs for one recipient? American Journal of Transplantation 13(7): 1806-16. Jul 2013. PMID: 23718142.
  19. Aufhauser DD Jr, Rose T, Levine M, Barnett R, Ochroch EA, Aukberg S, Greenblatt E, Olthoff K, Shaked A, Abt P.  Cardiac arrest associated with reperfusion of the liver during transplantation: incidence and proposal for a management algorithm Clinical Transplantation 27(2): 185-92. Mar-Apr 2013. PMID: 23278482.
  20. Hsu JW, Reese PP, Naji A, Levine MH, Abt PL.  Inferior early posttransplant outcomes of right versus left deceased and living donor kidneys (letter)  American Journal of Transplantation 13(11): 2048. Nov 2013. PMID: 24102734.
  21. Reese PP, Bloom RD, Shults J, Thomasson A, Mussell A, Rosas SE, Johnasen KL, Abt P, Levine M, Caplan A, Feldman HI, Karlawish J.  Functional Status and Survival After Kidney Transplantation.  Transplantation Epub  2013.  PMID:24113514.
  22. Harhay M, Lin E, Pai A, Harhay MO, Huverserian A, Mussell A, Abt         P, Levine M, Bloom R, Shea JA, Troxel AB, Reese PP.  Early Rehospitalization After Kidney Transplantation: Assessing Preventability and Prognosis.  American Journal of Transplantation Epub 2013.  PMID: 24165498.
  23. Yoo PS, Bonnel A, Kamoun M, Levine MH.  Clinical outcomes among renal transplant recipients with pre-transplant weakly reactive donor-specific antibodies. Clinical Transplantation  Epub.  PMID: 24345281.
  24. Wolf JH, Bhatti TR, Fouraschen S, Chakravorty S, Wang L, Kurian S, Salomon D, Olthoff KM, Hancock WW, Levine MH.  Heat shock protein-70 is required for optimal liver regeneration after partial hepatectomy in mice.  Liver Transplantation  Epub  PMID: 24357103.
  25. Bahirwani R, Forde KA, Mu Y, Lin F, Reese P, Goldberg D, Abt P, Reddy KR, Levine M.  End-stage renal disease after liver transplantation in patients with pre-transplant chronic kidney disease.  Clinical Transplantation  Epub.  PMID: 24382253.
  26. Clayton EF, Malik S, Bonnel A, Mu Y, Olthoff O, Shaked A, Abt PL, Peterman H, Reddy KR, Ottmann S, Furth EE, Levine MH.  Liver Transplantation and Cirrhotomimetic Hepatocellular Carcinoma: Classification and Outcomes.  Liver Transplantation  Epub.  PMID: pending.

Reviews in Peer Reviewed Research Publications

  1. Levine MH, Abt P.  Treatment options and strategies for antibody mediated rejection after renal transplantation.  Seminars in Immunology 24(2):136-142, Apr. 2012. PMID 21940179.
Research Publications, Non-Peer Reviewed
  1. Levine MH. Peripheral B cell selection on the basis of BCR: Identification and characterization. PhD Thesis, Yale University School of Medicine, Department of Immunobiology, 2001.
  2. Wang GJ, Levine MH. Endovascular Therapy for Renal Transplant Salvage. Endovascular Today 25-7, Jul. 2010.
Abstracts
  1. Cassuto J, Bloom R, Levine M, Sonnad S, Olthoff K, Shaked A, Naji A, Abt P. “Wait List Death and Survival Benefit of Kidney Transplantation Among Extra-Renal Transplant Recipients.” American Society of Transplant Surgeons, 10th Annual State of the Art Winter Symposium Ft. Lauderdale, FL Jan 2010.
  2. Cassuto J, Bloom R, Reese P, Levine M, Sonnad S, Olthoff K, Shaked A, Abt P. “Implications of HCV Status on Kidney Graft Survival in the Settings of a Previous or Simultaneous Liver Transplant: The Role of Induction Therapy.” American Society of Transplant Surgeons, 10th Annual State of the Art Winter Symposium Ft. Lauderdale, FL Jan 2010.
  3. Hsu J, Reese P, Levine M, Naji A, Abt P. “Increased Graft Failure in Right-Sided Donor Nephrectomies.” American Society of Transplant Surgeons, 10th Annual State of the Art Winter Symposium Ft. Lauderdale, FL Jan 2010.
  4. Waters J, Cassuto J, Naji A, Levine M, Reese P, Bloom R, Abt P. “ABO Incompatible Kidney Transplantation: Graft Survival Trends.” American Society of Transplant Surgeons, 10th Annual State of the Art Winter Symposium Ft. Lauderdale, FL Jan 2010.
  5. Levine MH, Ottmann S, O’Donnell P, Nangeroni J, Metin M, Furth E, Sonnad S, Abt P, Reddy R, Olthoff K, Shaked A. “Analysis of Unrecognized Tumor Burden in Patients Transplanted for Hepatocellular Carcinoma – Implications for Offering Resection to Cirrhotic Patients.” American Transplant Congress San Diego, CA May 2010.
  6. Ottmann S, O’Donnell P, Nangeroni J, Metin M, Furth E, Sonnad S, Abt P, Reddy R, Olthoff K, Shaked A, Levine MH,. “Lymphovascular Invasion and Hepatocellular Carcinoma: Lessons Learned From Explant Liver Specimens.” American Transplant Congress San Diego, CA May 2010.
  7. Redfield RR, Parsons R, Sonnad S, Levine M, Abt P. “A2 ABO Incompatible Kidney Transplantation: Short and Long-term Graft Survival.” American Transplant Congress San Diego, CA May 2010.
  8. Levine MH, Wang Y, Hancock WW. “Class Specific Histone Deacetylase Inhibition Improves Tolerance of Renal Ischemia Reperfusion Injury.” 6th Academic Surgical Congress Huntington Beach, CA Feb 2011.
  9. Levine MH, Wood A, Baluarte, HJ, Naji A, Reese P, Abt P. “Recipient Age at Transplant: Impact on Graft Survival of Highest Quality Deceased-Donor Renal Allografts.” Oral Presentation, American Society of Transplant Surgeons, 11th Annual State of the Art Winter Symposium, Hollywood, FL Jan 2011.
  10. Levine MH, Wang Y, Hancock WW.: Class Specific Histone Deacetylase Inhibition Improves Tolerance of Renal Ischemia Reperfusion Injury. 6th Academic Surgical Congress, Huntington Beach, CA  Feb 2011 Notes: Oral Presentation.
  11. Akimova T, Levine M, Hancock W: Relationship of Calcineurin Inhibitors (CNI),Foxp3 Demethylation and Suppressive Function of T Regulatory (Treg) Cells in Adult Liver Transplant (Tx) Recipients. American Transplant Congress, Philadelphia, PA  Apr 2011.
  12. Hoteit M, Levine M, Sun W, Giantonio B, Reddy R, Olthoff K, Shaked A: Pattern of Recurrence of Hepatocellular Carcinoma after Liver Transplantation Factors Affecting Survival. American Transplant Congress, Philadelphia, PA  Apr 2011.
  13. Levine MH, Fan E, Ottmann S, Drazek D, Bonnell A, Mu Y, Olthoff K, Shaked A, Furth E. : Categorization of Cirrhotomimetic Growth Patterns in Explanted Liver Specimens and Correlation with Tumor Recurrence and Patient Survival.  American Transplant Congress, Philadelphia, PA  Apr 2011.
  14. Levine MH, Sonnad S, Porrett P, Cui R, Ottmann S, Hoteit M, Abt P, Furth E, Siegelman E, Rosen M, Olthoff K, Shaked A: Unexpected Multicentricity in Liver Explant Data from 358 Consecutive Liver Transplants for HCC: Implications for Resection in Cirrhotic Patients. American Transplant Congress, Philadelphia, PA  Apr 2011.
  15. Levine MH, Sonnad S, Porrett P, Ottmann S, Cui R, Hoteit M, Rosen M, Siegelman E, Furth E, Olthoff K, Shaked A: The Predictive Value of Milan Criteria for Liver Transplantation for Hepatocellular Carcinoma is Derived from Correlation with Explant Liver Pathology.  American Transplant Congress,Philadelphia, PA  Apr 2011.
  16. Levine MH, Wang Y, Bhatti T, Han R, Hancock WW: Histone Deacetylase Inhibition Leads to Improved Tolerance of Renal Ischemia-Reperfusion Injury and Modulation of Heat Shock Protein Expression. American Transplant Congress, Philadelphia, PA  Apr 2011.
  17. Mu Y, Abt P, Levine M, Olthoff K, Shaked A: Consequences and Pattern of Injury Following Late Acute Celluar Rejection in Liver Transplant Recipients. American Transplant Congress, Philadelphia, PA  Apr 2011.
  18. Mu Y, Abt P, Levine M, Porrett P, Ottmann S, Olthoff K, Shaked A: Survival after Tumor Resection of HCC Single Metastases Following Liver Transplantation. American Transplant Congress, Philadelphia, PA  Apr 2011.
  19. Porrett P, Cui R, Sonnad S, Ottmann S, Drazek D, Hoteit M, Olthoff K, Shaked A, Levine M: Impact of True MELD ON Post-Transplant Outcome in Patients Listed with Exception MELD HCC Points. American Transplant Congress, Philadelphia, PA  Apr 2011.
  20. Porrett P, Cui R, Sonnad S, Ottmann S, Drazek D, Hoteit M, Olthoff K, Shaked A, Levine M: Prolonged Wait List Time Does Not Negatively Impact Oncologic Outcome in Patients Transplanted with HCC. American Transplant Congress, Philadelphia, PA  Apr 2011.
  21. Reese P, Bloom R, Abt P, Huverserian A, Mussell A, Weng F, Doshi M, Levine M, Goral S, Blosser C: Reporting of Race and Enrollment of Black Patients in Clinical Trials of Kidney Transplant Recipients  American Transplant Congress, Philadelphia, PA Apr. 2011.
  22. Levine M, Bonnel A, Kearns J, Yoo P, Kamoun M: Weakly Reactive Pre-transplant DSA Combined with Stringent Final Cross-Match are not Associated with Adverse Short-Term Kidney Transplant Outcomes. American Society For Histocomatibility and Immunogenetics 37th Annual Meeting, New Orleans, LA  Oct.  2011.
  23. Akimova T, Levine M, Beier U, Kamath B, Rand E, Meyers K, Goebel J, Bucuvalas J, Hancock W: Contrasting Effects of Immunosuppression on FOXP3+ Treg Biology in Liver and Kidney Allograft Recipients. American Society of Nephrology, Philadelphia, PA  Nov. 2011.
  24. Akimova T, Levine M, Beier U, Kamath B, Rand E, Meyers K, Goebel J, Bucuvalas J, Hancock W: Contrasting Effects of Immunosuppression on FOXP3+ Treg Biology in Liver and Kidney Allograft Recipients. American Society of Nephrology Kidney Week 2011, Philadelphia, PA  Nov. 2011.
  25. Levine M, Enestvedt K, Porrett P, Cui R, Hoteit M, Mu Y, Siegelman E, Sonnad S, Abt P Shaked A, Olthoff K: Incidental Hepatocellular Carcinoma in Liver Transplant Recipients Is Associated With Fatty Liver Disease and Conveys A Low Risk of Recurrent Malignancy After Transplant  7th Annual Academic Surgical Congress, Las Vegas, NV Feb. 2012.
  26. Mu Y, Sonnad S, Abt P, Levine M, Olthoff K, Shaked A: Late Acute Cellular Rejection after Liver Transplantation: Patterns of Injury Chronic Rejection and Graft Survival. ILTS 18th Annual International Congress, San Francisco, CA  May  2012.
  27. Surrey L, Ochs R, Clayton E, Levine M, Furth E: Mitotic and Apoptotic Indices but Not Nuclear Grade of Hepatocellular Carcinomas in the Liver Explant Predict Tumor Recurrance Post Liver Transplantation. United States and Canadian Academy of Pathology 101st Annual Meeting, Vancouver, BC  May 2012.
  28. Bahirwani R, Forde K, Mu Y, Lin F, Reese P, Abt P, Reddy R, Levine M: End Stage Renal Disease after Liver Transplantation in Patients with Pre-Transplant Chronic Kidney Disease  American Transplant Congress, Boston, MA June  2012.
  29. Charak G, Guzman A, Abt P, Goldberg D, Levine M, Olthoff K, Shaked A: Early Allograft Dysfunction Is Not Associated with Graft Failure in Liver Recipients of High Donor Risk Index Organs. American Transplant Congress, Boston, MA June  2012.
  30. Enestvedt K, Malik S, Goldberg D, Porrett P, Levine M, Olthoff K, Shaked A, Abt P: Predicting Survival Following Liver Re-transplantation: Validation of a Donor-Derived Scoring System. American Transplant Congress, Boston, MA June 2012.
  31. Eyileten T, Trofe-Clark J, Goral S, Sawinski D, Bleicher M, Levine M, Abt P, Ende L, Van Deerlin V, Bloom R: Single Center Experience with Prospective BK Monitoring in Renal Transplantation.   American Transplant Congress,  Boston, MA  June 2012.
  32. Goldberg D, Ruebner R, Bahirwani R, Abt P, Levine M, Sawinski D, Bloom R, Reese P: Risk of End Stage Renal Disease after Liver Transplant among Recipients with Sustained Pre-Transplant Renal Dysfunction  American Transplant Congress, Boston, MA June  2012.
  33. Gupta M, Wood A, Abt P, Levine M: Pediatric First Kidney Transplant Graft Survival Correlates with Second Transplant Graft Survival. American Transplant Congress, Boston, MA June  2012.
  34. Malik S, Sonnad S, Fayek S, Olthoff K, Abt P, Levine M, Shaked A: Donor and Peri-Operative Variables Impacting Liver Re-transplantation Outcomes. American Transplant Congress, Boston, MA June  2012.
  35. Nair M,Ruskin L, Chiang C, Abt P, Huverserian A, Mussell A, Schaeffer G, Doll S, Reese P, Levine M: Categories and Predictors of Early Re-Hospitalization after Kidney Transplantation  American Transplant Congress, Boston, MA June 2012.
  36. Porrett P, Malik S, Cui R, Ottmann S, Drazek D, Hoteit M, Abt P, Shaked A, Olthoff K, Levine M: Increasing Wait Time Does Not Adversely Impact Wait List or Transplant Outcomes in Patients with HCC  American Transplant Congress, Boston, MA June  2012 Note: Oral Presentation.
  37. Reese P, Bloom R, Shults J, Thomasson A, Mussell A, Rosa S, Johansen K, Abt P, Levine M, Nair M, Caplan A, Feldman H, Karlawish J: Waiting List Functional Status Is A Potent Predictor of Mortality among Adult Kidney Transplant Recipients, Regardless of Age. American Transplant Congress, Boston, MA June  2012.
  38. Sawinski D, Patel H, Haddad D, Abt P, Levine M, Reese P, Goral S, Bleicher M, Reddy R, Bloom R: Pre-transplant Liver Histology and Post-transplant Outcome in HCV+ Kidney Recipients  American Transplant Congress, Boston, MA June  2012.
  39. Wang Y, Bhatti T, Han R, Hancock W, Levine M: Pan-Histone Protein Deacetylase (HDAC) Inhibition Improves Renal Ischemia Reperfusion Injury Tolerance In A Non-Class-Specific Fashion American Transplant Congress, Boston, MA  June  2012.
  40. Wang Y, Bhatti T, Han R, Wolf J, Hancock W, Levine M: Heat Shock Protein 70 Expression Does Not Mitigate Murine Renal Ischemia Reperfusion Injury. American Transplant Congress, Boston, MA June  2012.
  41. Gupta M, Wood A, Abt P, Levine M:  Pediatric First Kidney Transplant Graft Survival Correlates with Second Transplant Graft Survival. International Pediatric Transplant Association Meeting, Heidelberg, Germany.  June 2012. Note: Oral Presentation.
  42. Levine MH, Bhatti T, Wang Y, Wang Z, Hancock WW:  Pan Histone-Protein Deacetylase Inhibition Protects Early Renal Function and Inhibits Fibrosis in Renal Ischemia Reperfusion Injury.  ASN Kidney Week San Diego, CA.  Nov 2012.
  43. Reese PP, Bloom RD, Shults J, Mussel AS, Rosas SE, Johansen KL, Abt P, Levine MH, Caplan A, Karlawish J, Feldman HI:  The Influence of Functional Status on Outcomes for Patients Awaiting Kidney Transplant.  ASN Kidney Week San Diego, CA.  Nov 2012.
  44. Hancock WW, Levine MH, Beier UH, Wang L, Simmons RA, Sasson I, Akimova T:  Obesity Impairs Foxp3+ Treg Cell Function in Clinical Allograft Recipients.  ASN Kidney Week San Diego, CA.  Nov 2012.
  45. Levine MH, Wang Z, Wang Y, Redfield RR, Abt PL, Wang L, Hancock WW: Gender Difference in Renal Ischemia Tolerance is Extrinsic to the Kidney.  American Transplant Congress Seattle, WA.  May 2013.
  46. Akimova T, Kamath B, Goebel J, Meyers KEC, Rand EB, Levine MH, Bucuvalas JC, Hancock WW:  Problems and Pitfalls in Calculation of “True” Treg Numbers Using Assays of Foxp3 TSDR Demethylation in PBMC of Transplant Recipients.  American Transplant Congress Seattle, WA.  May 2013.
  47. Redfield R, Wood A, Abt P, Levine M:  The Survival Benefit of a Third Kidney Transplant.  American Transplant Congress Seattle, WA.  May 2013.  Note: Oral Presentation
  48. Stevens D, Trofe-Clark J, Blumberg E, Wilck M, Goral S, Bleicher M, Sawinski D, Abt P, Levine M, Porrett P, Bloom R:  Increased Risk of Breakthrough Infection Among Cytomegalovirus Donor Positive/Recipient Negative Kidney Transplant Recipients Receiving Lower Dose Valgancyclovir Prophylaxis.   American Transplant Congress Seattle, WA.  May 2013.
  49. Gupta M, Wood A, Mitra N, Furth S, Abt P, Levine M: Good Second Kidney Transplant Outcomes in Pediatric Patients With Early First Kidney Graft Loss.  American Transplant Congress Seattle, WA.  May 2013.
  50. Gupta M, Porrett P, Goldberg D, Abt P, Levine M: True MELD Score is Associated with HCC Patient Outcomes After Liver Transplant.  American Transplant Congress Seattle, WA.  May 2013.  Note: Oral Presentation
  51. Gupta M, Wood A, Mitra N, Furth S, Abt P, Levine M:  First Kidney Graft Survival is Associated with Second Kidney Transplant Outcomes in Pediatric Patients with Highly Recurrent Disease.  American Transplant Congress Seattle, WA.  May 2013.
  52. Nair M, Lin E, Pai A, Harhay M, Huverserian A, Mussel A, Troxel A,  Bloom R, Levine M, Abt P, Shea J, Reese P:  Early Rehospitalization after Kidney Transplantation: Predictors and Prognosis.  American Transplant Congress Seattle, WA.  May 2013.  Note: Oral Presentation.
  53. Nair M, Lin E, Pai A, Harhay M, Huverserian A, Mussel A, Troxel A,  Levine M, Shea J, Abt P, Bloom R, Reese P:  Assessment of Preventable and Non-preventable Early Rehospitalization Following Kidney Transplantation.  American Transplant Congress Seattle, WA.  May 2013.  Note: Oral Presentation.
  54. Gupta M, Snider M, Wood A, Abt P, Levine M:  Second Allograft Outcomes in Patients with Renal Transplants: Past Performance Informs Future Performance.  American College of Surgeons, Surgical Forum Washington, DC. Sep 2013.  Note: Oral Presentation.
  55. Levine MH, Wang Z, McNeal S, Batti T, Hancock WW:  Gender Differences in Murine Ischemia Reperfusion Tolerance Is Extrinsic to the Kidney Itself: Lessons From Transplantation.  ASN Kidney Week 2013.  Atlanta, GA  Nov 2013.
  56. Gupta M, Wood A, Abt PL, Levine MH:  The Impact of the Share 35 Policy on First Allograft Outcomes Among Kidney Transplant Recipients. American Society of Transplant Surgeons, Winter Symposium, Miami FL.  Jan 2014.
  57. Levine MH: Gender Differences in Murine Ischemia Reperfusion Tolerance Is Extrinsic to the Kidney Itself: Lessons From Transplantation. Academic Surgical Congress San Diego, CA.  Feb 2014.  Note: SUS New Member Poster Presentation

Editorials, Chapters & Participation in Committee Reports

  1. Levine MH, Feng S: Clinical Allograft Rejection Syndromes: Diagnosis and   Management: Liver. Textbook of Organ Transplantation  Kirk A, Knechtle S, Larsen C, Madsen J, Pearson T (eds.). 2012 Notes: In Submission.
  2. Levine MH:  Liver Transplant – Standard Arterial Reconstruction.  Operative Techniques in Surgery.  Mulholland M , Albo D, Engelsbe M, Hawn M, Hughes S, Sabel M, Dalman R (eds.) 2013 Notes: In Submission.
 
Awards, Honors and Membership in Honorary Societies
2011 “Top 10” Oral Abstract, 11th Annual ASTS Winter Symposium
Hollywood, FL
 
2009 McCabe Fund Pilot Research Award
University of Pennsylvania
 
2007 Fellows Excellence in Research Award, Fellows Educational Travel Grant
Transplant Summit 2007: Defining the Future, Chicago, Illinois
 
2001 The MD/PhD Award, Yale University School of Medicine
 
1994 Medical Scientist Training Program Fellowship (NIH) for MD/PhD training
Yale University School of Medicine
 
1994 Elected to Phi Beta Kappa, Biochemistry Honors
Leallyn B. Clapp Prize for best senior honors thesis in biochemistry, Brown University
 
1994  Ratcliffe Hicks Prize in Theater, Speech, and Dance for Excellence in Debate
Brown University
 
1993  Elected to Sigma Xi, Howard Hughes Grant Fellowship for Summer Research
Brown University
 
1993   Named Faculty Scholar by nomination and election of faculty
Susan Rosenberger Prize for Outstanding Junior Concentrator in Biochemistry
Brown University
 
1992   Undergraduate Teaching and Research Assistantship Grant for summer research
Brown University

Dr. Matthew Levine

 
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