Dr. Mattei is Assistant Professor of Surgery at The University of Pennsylvania School of Medicine and Attending Physician in the Division of General, Thoracic and Fetal Surgery at The Children’s Hospital of Philadelphia. He is certified by the American Board of Surgery in General Surgery and Pediatric Surgery. He specializes in all aspects of pediatric general and thoracic surgery, newborn surgery, and hernia surgery, with special expertise in pediatric surgical oncology, surgical treatment of inflammatory bowel disease, and minimally invasive surgery, including daVinci robotic-assisted laparoscopy and thoracoscopy.

Dr. Mattei attended the University of Pennsylvania and earned his medical degree from Harvard Medical School. He completed General Surgery training at The Johns Hopkins Hospital and a Pediatric Surgery fellowship at Cincinnati Children’s Hospital Medical Center. He was voted one of the Top Docs for Kids in Philadelphia Magazine in 2001 and one of the Best Doctors in America on multiple occasions.

Dr. Mattei is a fellow of several major surgical and pediatric surgical associations including the American College of Surgeons, the American Pediatric Surgical Association, the American Academy of Pediatrics, and the College of Physicians in Philadelphia. He has authored many peer-reviewed articles and book chapters, and has published a major textbook of pediatric surgery, Surgical Directives: Pediatric Surgery.

• National Societies: American Pediatric Surgical Association (Fellow 2001- )
  • APSA Cancer Committee (2007- , Vice-Chairman 2008- )
• International Pediatric Endosurgery Group (Fellow 2006- )
• American Academy of Pediatrics, Surgical Section
  (Fellow, 2000-present, Publications Committee, 2001)
• American College of Surgeons (Fellow, 2001- )
• Cancer Liaison Physician, Commission on
  Cancer, 1999-2003
• Association for Academic Surgery (Fellow 2000-2007)

• College of Physicians of Philadelphia (Fellow, 2006- )

• Children's Oncology Group (Member 2001- )

1. Bornslaeger EA, Mattei P, Schultz RM: Involvement of cAMP-dependent protein kinase and protein phosphorylation in regulation of mouse oocyte maturation. Developmental Biology 114(2):453-462, Aug. 1986.
2. Bornslaeger EA, Poueymirou WT, Mattei P, Schultz RM: Effects of protein kinase C activators on germinal vesicle breakdown and polar body emission of mouse oocytes. Experimental Cell Research 165(2):507-517, Aug. 1986.
3. Endo Y, Mattei P, Kopf GS, Schultz RM: Effects of phorbol esters on mouse eggs: dissociation of sperm receptor activity from acrosome reaction-inducing activity of the mouse zona pellucida protein, ZP3. Developmental Biology 123(2):574-577, Oct. 1987.
4. Bornslaeger EA, Mattei P, Schultz RM: Protein phosphorylation in meiotically competent and incompetent mouse oocytes. Molecular Reproductive Development 1(1): 19-25, 1988.
5. Schultz RM, Endo Y, Mattei P, Kurasawa S, Kopf GS: Egg-induced modifications of the mouse zona pellucida. Progress in Clinical Biological Research 284:77-92, 1988.
6. Mattei P, Wiebke E, Lipsett P: Tension pneumothorax as a presentation of traumatic diaphragmatic hernia. Southern Medical Journal 85(8):847-850, Aug. 1992.
7. Sola JE, Mattei P, Pegoli W, Jr., Paidas CN: Rupture of the right diaphragm following blunt trauma in an infant. Journal of Trauma 36(3):417-420, Mar. 1994.
8. Mattei P, Sola JE, Yeo CJ: Chronic and recurrent appendicitis: Unusual entities often misdiagnosed. Journal of the American College of Surgeons 178(4):385-389, Apr. 1994.
9. Mattei P, Taylor GA, Colombani PM: Post-traumatic hepatic vein thrombosis (Budd-Chiari syndrome) in a child: Case report and review of the literature. Pediatric Surgery International 9(5-6):425-428, 1994.
10. McKee M, P Mattei, K Schwarz, B Wise, P Colombani: Steroid withdrawal in Tacrolimus (FK506)-treated pediatric liver transplant recipients. Journal of Pediatric Surgery 32(7):973-975, July 1997.
11. Mattei P, Wise B, Schwarz K, Klein A, Colombani PM: Orthotopic liver transplantation in patients with biliary atresia and situs inversus: Report of two cases and review of the literature. Pediatric Surgery International 14(1-2):104-110, Nov. 1998.
12. Mattei P, Wolfson P: Prior gastrostomy does not preclude successful laparoscopic fundoplication. Pediatric Endosurgery & Innovative Techniques 5(3):277-280, 2001.
13. Mattei P, Alonso M, Justinich C: Laparoscopic repair of colon perforation after colonoscopy in children: Report of two cases and review of the literature. Journal of Pediatric Surgery 40(10):1651-1653, 2005.
14. Liu S, de Blacam C, Lim FY, Mattei P, Mamula P: Magnetic foreign body ingestions leading to duodenocolonic fistula. Journal of Pediatric Gastroenterology and Nutrition 41(5):670-672, 2005.
15. Mattei P, von Allmen D, Piccoli D, Rand E: Relief of intractable pruritis in Alagille syndrome by partial external biliary diversion. Journal of Pediatric Surgery 41(1):104-107, 2005.
16. Artz GJ, Reilly JS, Mattei P: Stridor in an infant. Clinical Pediatrics 45(6):578-581, 2006.
17. Adibe O, Nichol PF, Flake AW, Mattei P: Comparison of outcomes after laparoscopic and open pyloromyotomy at a high-volume pediatric teaching hospital. Journal of Pediatric Surgery 41(10):1676-1678, 2006.
18. Mattei P, Tyler DC: Carbon dioxide embolism during laparoscopic cholecystectomy due to a patent para-umbilical vein. Journal of Pediatric Surgery 42(3):570-2, 2007.
19. Mattei P: Urachal remnant perforation during umbilical vein catheterization in a newborn. Journal of Pediatric Surgery 42(4):722-724, 2007.
20. Adibe O, Nichol PF, Lim FY, Mattei P: Ad Libitum Feeds After Laparoscopic Pyloromyotomy: A Retrospective Comparison with a Standardized Feeding Regimen in 227 Patients. Journal of Laparoendoscopic & Advanced Surgical Techniques 17(2):235-237, 2007.
21. Dunning K, Mattei P: Burkitt’s Lymphoma Presenting as Colonic Ischemia and Overwhelming Sepsis. Journal of Pediatric Surgery 42(8):E15-7, 2007.
22. Adibe O, Barnaby K, Dobies J, Comerford M, Drill A, Walker N, Mattei P: Postoperative antibiotic therapy for children with perforated appendicitis: Long course of intravenous antibiotics versus early conversion to an oral regimen. The American Journal of Surgery 195(2):141-143, 2008.
23. Jatla M, Bates NA, Mattei P: Fellow’s Corner: Meckel’s Diverticulum. Practical Gastroenterology 32(4): 67, 72, 2008.
24. Kaye AJ, Jatlab M, Mattei P, Kelly J, Nance ML: Use of laparoscopic cholecystectomy for biliary dyskinesia in the child. Journal of Pediatric Surgery 43(6):1057-1059, 2008.
25. Kaye AJ, Slemp AE, Chang B, Mattei P, Fairman R, Velasquez OC: Complex vascular reconstruction of abdominal aorta and its branches in the pediatric population. Journal of Pediatric Surgery 43(6):1082-1088, 2008.
26. Mattei P, Barnaby K: Rapid regression of duodenal inflammatory myofibroblastic tumor after intravenous ketorolac: Case report and review of the literature. Journal of Pediatric Surgery 43(6):1196-1199, 2008.
27. Laje P, Mattei P: Laparoscopic adrenalectomy for adrenal tumors in children: a case series. Journal of Laparoendoscopic & Advanced Surgical Techniques 19(Suppl.1): S27-29, 2009.
28. Mattei P: A simple suture-retrieval device for the placement of U-stitches during laparoscopic gastrostomy. Journal of Laparoendoscopic & Advanced Surgical Techniques 19(1):115-117, 2009.

1. Adibe O, Nichol PF, Flake AW, Mattei P: Retrospective comparison of outcomes following laparoscopic versus open pyloromyotomy. Presented at the International Pediatric Endosurgery Group annual conference, Venice, Italy, 2005
2. Mattei P, von Allmen D, Piccoli D, Rand E: Relief of intractable pruritis in Alagille syndrome by partial external biliary diversion. (Presented at the American Pediatric Surgical Association 36th Annual Meeting, Phoenix, AZ, 2005.
3. Adibe O, Barnaby K, Dobies J, Comerford M, Drill A, Walker N, Mattei P: Postoperative Antibiotic Therapy for Children with Perforated Appendicitis: Long Course of Intravenous Antibiotics versus Early Conversion to an Oral Regimen, Poster Presentation, Society of Black Academic Surgeons Scientific Symposium April 13-14, 2007.
4. Gollomp K, White C, Rankin SC, Mattei P, Harris MC, Kilpatrick L, Sheffler-Collins S, Paul B, McGowan KL, Shah SS. Presented at the Annual meeting of the Pediatric Academic Societies, Vancouver, Canada, May 1-4, 2010.
5. White CA, Gollomp K, Kilpatrick L, Harris MC, Mattei P, Sheffler-Collins S, Paul B, Rankin S, McGowan K, Shah SS. Pleural fluid cytokine levels in children with complicated pneumonia. Presented at the Annual meeting of the Pediatric Academic Societies, Vancouver, Canada, May 1-4, 2010.
6. Taheri H, Mattei P. Superior mesenteric artery syndrome following laparoscopic-assisted proctocolectomy and ileal J-pouch-anal anastomosis in a pediatric patient. Poster Presentation, SAGES, Washington, D.C., April, 2010.

1. Pegoli W, Jr, Mattei P, Colombani PM: Congenital intrathoracic vascular anomalies in childhood. Chest Surgery Clinics of North America 3(3):529-546, 1993.
2. Paidas CN, Mattei P, Schlein CZ, Clemens M: Splanchnic function and heart disease. In Nichols DG, Cameron DA, Greeley WJ, et al (eds).: Critical Heart Disease in Infants and Children. St. Louis: Mosby, pp. 143-155, 1995.
3. Mattei P, Sola JE: Gastrointestinal procedures. In Chen H, Sola JE, Lillemoe KD (eds): Manual of Common Bedside Surgical Procedures. Baltimore: Williams & Wilkins, pp. 131-163, 1996.
4. Gingalewski C, Mattei P: Pediatric surgery. In Blackbourne LH, Fleischer KJ (eds): Advanced Surgical Recall. Baltimore: Williams & Wilkins, pp. 844-891, 1997.
5. Mattei P, Stevenson RJ, Ziegler MM: Appendicitis. In Wyllie R and Hyams J (eds): Pediatric Gastrointestinal Disease. Philadelphia: W.B. Saunders Co., pp. 466-471, 1999.
6. Mattei P: Transfusion medicine and coagulation disorders. In Ziegler MM, Azizkhan RG, and Weber TR (eds): Operative Pediatric Surgery. New York: McGraw-Hill Cos., pp. 153-160, 2003.
7. Mattei P: Vascular access. In Mattei P (ed): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.55-60, 2003.
8. Queenan J and Mattei P: Head trauma. In Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.99-102, 2003.
9. Mattei P: Torticollis. In Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.193-196, 2003.
10. Mattei P: Meconium ileus. In Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.317-322, 2003.
11. Mattei P: Benign skin lesions. In Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.671-676, 2003.
12. Mattei P: Abdominal pain in Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.781-786, 2003.
13. Queenan J and Mattei P: Ventricular shunts for hydrocephalus: General surgical issues. In Mattei P (ed.): Surgical Directives: Pediatric Surgery. Philadelphia: Lippincott, Williams & Wilkins, pp.793-796, 2003.
14. Schwartzentruber DJ, Hostetter RB, Mattei P: Surgery in the setting of hematologic diseases. In Young NS, Gerson SL, and High KA (eds): Clinical Hematology. Philadelphia: Mosby Elsevier, pp. 1179-1188, 2005.
15. Mattei P, Rombeau JL: Review of the pathophysiology and management of postoperative ileus. World Journal of Surgery 30(8): 1382-1391, 2006.
16. Ryan M, Mattei P, Russo P, Flick J, Mamula P: A 2-year-old girl with chronic and recurrent emesis. Medscape General Medicine 8(1): 10, 2006.
17. Mattei P, Allen JL: Treatment of empyema in children: from Hippocrates' time to the present, and back again. American Journal of Respiratory and Critical Care Medicine 15;174(2):110-1, 2006.
18. Mattei P, Allen JL: Treatment of empyema in children: from Hippocrates’ time to the present, and back again. American Journal of Respiratory and Critical Care Medicine 174(2):110-111, 2006.
19. Mattei P: Minimally invasive surgery in the diagnosis and treatment of abdominal pain in children. Current Opinion in Peidatrics 19(3): 338-343, 2007.
20. Nichol PF, Mattei P: Hernias. In Zaoutis LB, Chiang V (eds): Pediatric Hospital Medicine. Philadelphia: Mosby/Elsevier, pp. 887-891, 2007.
21. Mattei P, von Allmen D: Treatment modalities: Surgery. In Brodeur GM, Manno CS (eds): Hematology/Oncology: Requisites in Pediatrics. Philadelphia: Elsevier, 2007.
22. Mattei P: Hirschsprung disease. In Liacouras C, Piccoli D (eds): Pediatric Gastroenter-ology: The Requisites in Pediatrics. Philadelphia: Elsevier, pp. 114-122, 2008.
23. Mattei P, Rombeau JL: Surgical Treatment of Ulcerative Colitis. In Mamula P, Markowitz JE, Baldassano RN (eds): Pediatric Inflammatory Bowel Disease. New York: Springer, pp. 469-483, 2008.
24. Swami S, Mattei P, Shah SS: Complicated Pneumonia. In Shah SS (ed.): Infectious Diseases New York: McGraw-Hill Medical, pp. 310-320.
25. Mattei P: Surgical Site Infections. In Shah SS (ed.): Infectious Diseases New York: McGraw-Hill Medical, pp. 738-750.

1. Mattei P (ed.): Surgical Directives: Pediatric Surgery. Lippincott, Williams & Wilkins, Philadelphia, 2003, 847 pages.
2. Mattei P (ed.): Fundamentals of Pediatric Surgery, 2nd Edition, Springer, New York, (in press, 2010).

1. "Living With IBD: What Patients and Families Should Know" DVD produced by The Children’s Hospital of Philadelphia and Primitive Worlds Productions, 2007.
2. “Therapeutic Options in Alagille Syndrome” DVD produced by The Children’s Hospital of Philadelphia and Primitive Worlds Productions, 2008.