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Robert E. Roses, M.D.
Endocrine and Oncologic Surgery

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Hospital of the University of Pennsylvania
3400 Spruce Street, 4 Silverstein
Philadelphia, PA 19104
Administrative Assistant: Malerie Hinkie
Fax: 215-615-0555

Clinical Office:
Perelman Center for Advanced Medicine
Cancer Center
West Pavilion, 4th Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104

Contact Information (internal use only)


Dr. Robert Roses is an Assistant Professor in the Division of Endocrine and Oncologic Surgery. Following training in general surgery at the University of Pennsylvania, he completed a fellowship in surgical oncology at University of Texas MD Anderson Cancer Center.  He completed a research fellowship at the University of Pennsylvania under the mentorship of Dr. Brian J. Czerniecki.  Clinical interests include malignancies of the liver, gastrointestinal tract and pancreas, and disorders of the adrenals and thyroid.


2012 - present Assistant Professor of Surgery at HUP, Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania
Hospital and Administrative Appointments
2012 - present  Attending Surgeon, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
1993 - 1997 B.A. - Dartmouth College
Hanover, New Hampshire
1999 - 2003   M.D. - Tufts University
Boston, Massachusetts
Postgraduate Training and Fellowship Appointments
2003 - 2004 Internship in Surgery, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
2004 - 2006 Residency in General Surgery, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
2006 - 2008  Research Fellow, Harrison Department of Surgical Research
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
2008 - 2010 Residency in General Surgery, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
2010 - 2012 Fellowship in Surgical Oncology, University of Texas/M.D. Anderson Cancer Center
Houston, Texas
2013 - present Society of Surgical Oncology
2011 - Present American College of Surgeons
Research Publications, peer reviewed (print or other media):
  1. Khitin L, Roses RE, Birkett DH: Cancer in the gastric remnant after gastric bypass: a case report. Current surgery 60(5): 521-3, Sep-Oct 2003.
  2. Xu JW, Zaporojan V, Peretti GM, Roses RE, Morse KB, Roy AK, Mesa JM, Randolph MA, Bonassar LJ, Yaremchuk MJ: Injectable tissue-engineered cartilage with different chondrocyte sources. Plastic and reconstructive surgery 113(5): 1361-71, Apr 2004.
  3. Xu JW, Randolph MA, Peretti GM, Nazzal JA, Roses RE, Morse KR, Yaremchuk MJ: Producing a flexible tissue-engineered cartilage framework using expanded polytetrafluoroethylene membrane as a pseudoperichondrium. Plastic and reconstructive surgery 116(2): 577-89, Aug 2005.
  4. Peretti GM, Campo-Ruiz V, Gonzalez S, Randolph MA, Xu JW, Morse KR, Roses RE, Yaremchuk MJ: Tissue engineered cartilage integration to live and devitalized cartilage: a study by reflectance mode confocal microscopy and standard histology. Connective tissue research 47(4): 190-9, 2006.
  5. Karakousis GC, Han D, Kelz RR, Nemani D, Karamacharya J, Roses RE, Gimotty PA, Fraker DL: Interpretation of intra-operative PTH changes in patients with multi-glandular primary hyperparathyroidism (pHPT). Surgery 142(6): 845-50; discussion 850.e1-2, Dec 2007.
  6. Roses RE, Xu S, Xu M, Koldovsky U, Koski G, Czerniecki BJ: Differential production of IL-23 and IL-12 by myeloid-derived dendritic cells in response to TLR agonists. Journal of immunology (Baltimore, Md. : 1950) 181(7): 5120-7, Oct 2008.
  7. Foley PJ, Roses RE, Kelz RR, Resnick AS, Williams NN, Mullen JL, Kaiser LR, Morris JB: The state of general surgery training: a different perspective. Journal of surgical education 65(6): 494-8, Nov-Dec 2008.
  8. Roses RE, Paulson EC, Sharma A, Schueller JE, Nisenbaum H, Weinstein S, Fox KR, Zhang PJ, Czerniecki BJ: HER-2/neu overexpression as a predictor for the transition from in situ to invasive breast cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 18(5): 1386-9, May 2009. PMCID: PMC2713817
  9. Bahl S, Roses RE, Sharma A, Koldovsky U, Xu S, Weinstein S, Nisenbaum H, Fox K, Pasha T, Zhang P, Araujo L, Carver J, Czerniecki BJ: Asymptomatic changes in cardiac function can occur in ductal carcinoma-in-situ patients following treatment with HER-2/neu-pulsed dendritic cell vaccines. American journal of surgery 198(4): 488-94, Oct 2009. PMCID: PMC2758542
  10. Roses RE, Foley PJ, Paulson EC, Pray L, Kelz RR, Williams NN, Morris JB: Revisiting the rotating call schedule in less than 80 hours per week. Journal of surgical education 66(6): 357-60, Nov-Dec 2009.
  11. Harada S, Mick R, Roses RE, Graves H, Niu H, Sharma A, Schueller JE, Nisenbaum H, Czerniecki BJ, Zhang PJ: The significance of HER-2/neu receptor positivity and immunophenotype in ductal carcinoma in situ with early invasive disease. Journal of surgical oncology 104(5): 458-65, Oct 2011. PMCID: PMC3168675
  12. Roses RE, Arun BK, Lari SA, Mittendorf A, Lucci A, Hunt KK, Kuerer HM: Ductal carcinoma-in-situ of the breast with subsequent distant metastasis and death. Annals of surgical oncology 18(10): 2873-8, Oct 2011.
  13. Aburabia MD, Roses RE, Kuerer HM, Fine R, Beitsch PD, Goyal S, Haffty B, Lyden M, Vicini FA: Axillary failure in patients treated with MammoSite accelerated partial breast irradiation. Annals of surgical oncology 18(12): 3415-21, Nov 2011.
  14. Sharma A, Koldovsky U, Xu S, Mick R, Roses RE, Fitzpatrick E, Weinstein S, Nisenbaum H, Levine BL, Fox K, Zhang P, Koski G, Czerniecki BJ: HER-2 pulsed dendritic cell vaccine can eliminate HER-2 expression and impact ductal carcinoma in situ. Cancer Jan 2012. PMCID: PMC3330145
  15. Alvarado R, Lari SA, Roses RE, Smith BD, Yang W, Mittendorf EA, Arun BK, Lucci A, Babiera GV, Wagner JL, Caudle AS, Meric-Bernstam F, Hwang RF, Bedrosian I, Hunt KK, Kuerer HM: Biology, Treatment, and Outcome in Very Young and Older Women with DCIS. Annals of surgical oncology May 2012.
  16. You YN, Roses RE, Chang GJ, Rodriguez-Bigas MA. Feig BW, Slack R, Nguyen S, Skibber JM: Multimodality salvage of recurrent disease after local excision for rectal cancer. Dis Colon Rectum 55(12): 1213-9, 2012.
  17. Zimmitti G, Roses RE, Andreou A, Shindoh J, Curley SA, Aloia TA, Vauthey JN: Greater complexity of liver surgery is not associated with an increased incidence of liver-related complications except fro bile leak: an experience with 2,628 consecutive resections. J Gastrointestinal Surg 2012.
  18. Bansal N, Sonnenberg EM, Meise CK, Reinke CE, Karakousis GC, Bartlett EK, Mahmoud NN, Roses RE, Kelz RR.: The effect of colorectal cancer screening mandates on access to care and clinical outcomes: a retrospective study of patients undergoing operations of the colon and rectum. Surgery 154(2): 335-44, August 2013.
  19. Fracol M, Xu S, Mick R, Fitzpatrick E, Nisenbaum H, Roses R, Fisher C, Tchou J, Fox K, Zhang P, Czerniecki BJ.: Response to HER-2 Pulsed DC1 Vaccines is Predicted by Both HER-2 and Estrogen Receptor Expression in DCIS. Ann Surg Oncol 20(10): 3233-9, October  2013.
  20. Bartlett EK, Gimotty PA, Sinnamon AJ, Wachtel H, Roses RE, Schuchter L, Xu X, Elder DE, Ming M, Elenitsas R, Guerry D, Kelz RR, Czerniecki BJ, Fraker DL, Karakousis GC.: Clark Level Risk Stratifies Patients with Mitogenic Thin Melanomas for Sentinel Lymph Node Biopsy. Ann Surg Oncol 2013.
  21. Bartlett EK, Meise C, Bansal N, Fischer JP, Low DW, Czerniecki BJ, Roses RE, Fraker DL, Kelz RR, Karakousis GC: Sartorius transposition during inguinal lymphadenectomy for melanoma Journal of Surgical Research 2013.
  22. Bartlett EK, Meise C, Roses RE, Fraker DL, Kelz RR, Karakousis GC.: Morbidity and Mortality of Cytoreduction with Intraperitoneal Chemotherapy: Outcomes from the ACS NSQIP Database. Ann Surg Oncol 2013.
  23. Bartlett EK, Roses RE, Gupta M, Shah PK, Shah KK, Zaheer S, Wachtel H, Kelz RR, Karakousis GC, Fraker DL: Surgery for metastatic neuroendocrine tumors with occult primaries. J Surg Res 2013.
  24. Bartlett EK, Roses RE, Meise C, Fraker DL, Kelz RR, Karakousis GC.: Preoperative radiation for retroperitoneal sarcoma is not associated with increased early postoperative morbidity. J Surg Oncol 2013.
  25. Kaseb AO, Shindoh J, Patt YZ, Roses RE, Zimmitti G, Lozano RD, Hassan MM, Hassabo HM, Curley SA, Aloia TA, Abbruzzese JL, Vauthey JN: Modified cisplatin/interferon α-2b/doxorubicin/5-fluorouracil (PIAF) chemotherapy in patients with no hepatitis or cirrhosis is associated with improved response rate, resectability, and survival of initially unresectable hepatocellular carcinoma. Cancer 2013.
  26. Zimmitti G, Vauthey JN, Shindoh J, Tzeng CW, Roses RE, Ribero D, Capussotti L, Giuliante F, Nuzzo G, Aloia TA.: Systematic use of an intraoperative air leak test at the time of major liver resection reduces the rate of postoperative biliary complications. J Am Coll Surg 217(6): 1028-37, December 2013.
  27. Roses RE, Tzeng CW, Ross MI, Fournier KF, Abbott DE, You YN.: The palliative index: predicting outcomes of emergent surgery in patients with cancer. J Palliat Med 17(1): 37-42, January 2014.
  28. Bartlett EK1, Wachtel H, Fraker DL, Vollmer CM, Drebin JA, Kelz RR, Karakousis GC, Roses RE: Surgical Palliation for Pancreatic Malignancy: Practice Patterns and Predictors of Morbidity and Mortality. J Gastrointest Surg 18(7): 1292-8, July 2014.
  29. Bartlett EK, Choudhury RA, Roses RE, Fraker DL, Kelz RR, Karakousis GC: Intraperitoneal Chemotherapy at the Time of Surgery is Not Associated with Increased 30-Day Morbidity and Mortality Following Colorectal Resection Ann Surg Oncol 2014.
  30. Datta J, Lewis RS Jr, Mamtani R, Stripp D, Kelz RR, Drebin JA, Fraker DL, Karakousis GC, Roses RE: Implications of inadequate lymph node staging in resectable gastric cancer: A contemporary analysis using the National Cancer Data Base. Cancer 2014.
  31. Dionisi F, Avery S, Lukens JN, Ding X, Kralik J, Kirk M, Roses RE, Amichetti M, Metz JM, Plastaras JP.: Proton therapy in adjuvant treatment of gastric cancer: Planning comparison with advanced x-ray therapy and feasibility report. Acta Oncol. 2014.
  32. Ecker BL, Bartlett EK, Hoffman RL, Karakousis GC, Roses RE, Morris JB, Kelz RR: Hernia repair in the presence of ascites J Surg Res 2014.
  33. Roses RE, Bartlett EK, Kelz RR, Drebin JA, Fraker DL, Karakousis GC: Morbidity and mortality after total gastrectomy for gastric malignancy using the American College of Surgeons National Surgical Quality Improvement Program database Surgery 2014.
  34. Wachtel H, Cerullo I, Bartlett EK, Roses RE, Cohen DL, Kelz RR, Karakousis GC, Fraker DL: Clinicopathologic Characteristics of Incidentally Identified Pheochromocytoma Ann Surg Oncol 2014.
Research Publications, peer-reviewed reviews
  1. Czerniecki BJ, Roses RE, Koski GK: Development of vaccines for high-risk ductal carcinoma in situ of the breast. Cancer research 67(14): 6531-4, Jul 2007.
  2. Roses RE, Xu M, Xu S, Koldovsky U, Son G, Koski GK: Working towards the development of vaccines for the treatment of of early breast cancer. Current Cancer Therapy Reviews 3: 97-107, 2007.
  3. Roses RE, Xu M, Koski GK, Czerniecki BJ: Radiation therapy and toll-like receptor signaling: implications for the treatment of cancer. Oncogene 27(2): 200-7, Jan 2008.
  4. Koski GK, Cohen PA, Roses RE, Xu S, Czerniecki BJ: Reengineering dendritic cell-based anti-cancer vaccines. Immunological reviews 222: 256-76, Apr 2008.
  5. Roses RE, Kuerer HM: Ductal Carcinoma In Situ: Clinical Trials Update and Resolving Controversies. Current Cancer Therapy Reviews 8: 182-188, 2012.
  6. Kaseb AO, Abaza YM, Roses RE: Multidisciplinary management of hepatocellular carcinoma. Recent Results Cancer Research 190: 247-59, 2013.
  7. Roses RE, Datta J, Czerniecki BJ: Radiation as Immunomodulator: Implications for Dendritic Cell-Based Immunotherapy. Radiat Res 2014.
Editorials, Reviews, Chapters, including participation in committee reports (print or other media)
  1. Roses RE, Rombeau JL: Recent trends in the surgical management of inflammatory bowel disease. World journal of gastroenterology : WJG 14(3): 408-12, Jan 2008. PMCID: PMC2679129
  2. Paulson EC, Roses RE, Morris JB: Laparoscopic Cholecystectomy. Gowner and Gloved Surgery: Introduction to Common Procedures. Roses RE, Paulson EC, Kanchwala SK, Morris JB (eds.). WB Saunders/Elsevier, Page: 92-101, 2009.
  3. Rodriguez JA, Roses RE, Braslow B: Appendectomy. Gowned and Gloved Surgery: Introduction to Common Procedures. Roses RE, Paulson EC, Kanchwala SK, Morris JB (eds.). WB Saunders/Elsevier, Page: 123-130, 2009.
  4. Roses RE: Sentinel lymph node biopsy and axillary dissection. Gowned and Gloved Surgery; Introduction to Common Procedures. Roses RE, Paulson EC, Kanchwala SK, Morris JB (eds.). WB Saunders/Elsevier, Page: 202-209, 2009.
  5. Roses RE, Czerniecki BJ: Mastectomy. Gowned and Gloved Surgery: Introduction to Common Procedures. Roses RE, Paulson EC, Kanchwala SK, Morris JB (eds.). WB Saunders/Elsevier, Page: 188-194, 2009.
  6. Roses RE, Kanchwala SK, Reilly PM: Perioperative Care. Gowned and Gloved Surgery: Introduction to Common Procedures. Roses RE, Paulson EC, Kanchwala SK, Morris JB (eds.). WB Saunders/Elsevier, Page: 1-7, 2009.
  7. Roses RE, Czerniecki BJ: The breast. The Surgical Review, Third Edition. Porrett PM, Frederick JR, Roses RE, Kaiser LR (eds.). Lippincott, Williams and Wilkins, Page: 252-262, 2010.
  8. Roses RE, Vauthey JN: Transplantation or resection for hepatocellular carcinoma: biology determines outcome. Oncology (Williston Park, N.Y.) 25(8): 760-1, Jul 2011.
  9. Roses RE, Morris JB: Incisions, Closures, and Management of the Abdominal Wound. Maingot's Abdominal Operations, 12th Edition. Zinner MJ, Ashley SW (eds.). McGraw Hill, Page: 99-122, 2013.
  10. Roses RE, Roses DF: Malignant Melanoma. Surgery: Evidence-Based Practice. Cohn SM, Brower ST (eds.). PMPH-USA, 2013.
  11. Roses RE, Vauthey JN: Hepatocellular Carcinoma: Epidemiology, Staging, Medical Management. Abrams Angiography, 3rd edition  Geschwind JH, Dake MD (eds.). Lippincott, Williams & Wilkins, 2013.
  12. Royal RE, Roses RE: Cancer of the Pancreas and Hepatobiliary Tracts. Oncology in Primary Care. Rose MG, DeVita VT, Lawrence TS, Rosenberg SA (eds.). Lippincott Williams & Wilkins, 2013.
  13. Roses RE, Rodriguez-Bigas M: The management of rectal cancer. Current Surgical Therapy, 11th edition. Cameron J, Cameron A (eds.). Elsevier, 2014.
  1. Porrett P, Frederick J, Roses RE, Kaiser LR: The Surgical Review. 3rd Edition. Lippincott, Williams and Wilkins, 2009.
  2. Roses RE, Paulson EC, Kanchwala SK, Morris JB: Gowned and Gloved. Introduction to Common Procedures. WB Saunders/Elsevier, 2010.
Awards, Honors and Membership in Honorary Societies
2009 Jonathan E. Rhoads Research Award, Hospital of the University of Pennsylvania
2006 Keith M. Reemtsma Surgical Resident of the Year Award
Hospital of the University of Pennsylvania
2003 Martin J. Loeb Memorial Award in Surgery, Tufts School of Medicine
2003 Alpha Omega Alpha Honor Society, Tufts School of Medicine
2001 Bernard G. Sarnat, MD Basic Science Award, PSEF Scientific Essay Contest
Plastic Surgery Educational Foundation

Dr. Robert Roses

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