Dr. Spray is chief of the Division of Cardiothoracic Surgery at The Children's Hospital of Philadelphia, director of the Hospital's Thoracic Organ Transplantation Program and Alice Langdon Warner professor of surgery at the University of Pennsylvania School of Medicine. Dr. Spray received his medical degree and training in general and cardiothoracic surgery at the Duke University School of Medicine. He continued specialty training at the National Institutes of Health before joining the staff at Washington University, St. Louis, going on to become chief of cardiothoracic surgery there. He joined the staff at The Children's Hospital of Philadelphia in 1994.

Dr. Spray takes a creative, individualized approach to reconstructive operations in neonates and infants and is a proponent of early corrective repair when possible. Dr. Spray has also maintained the Hospital's preeminence in the management of infants and children with complex "single ventricle" physiology. He is an internationally recognized leader in the application of the pulmonary autograft as a replacement for the aortic valve ("Ross procedure") in the pediatric population. He has contributed widely to the literature in congenital cardiothoracic surgery and holds numerous leadership positions in national and international professional associations.

Dr. Spray also brought to the institution unique capabilities in pediatric heart and lung transplantation. In just a few years, the program has become the most comprehensive service of its kind on the eastern seaboard. Infants and children with a wide variety of complex cardiac and pulmonary disorders, for whom transplantation is the optimal treatment, can be fully evaluated and treated by a specialized multidisciplinary team at Children's Hospital under Dr. Spray's direction. Recently, Dr. Spray performed the Hospital's first living-related donor lung transplant. He has also successfully transplanted a series of children following a period on extracorporeal membrane oxygenation (ECMO) as a "bridge" to transplant.

Under Dr. Spray's leadership, a multidisciplinary approach to the care of pediatric cardiothoracic patients was put in place. Cardiac services at Children's Hospital have now expanded to provide total care for the full range of infants and children with congenital cardiothoracic disorders.

• National: American Association for Thoracic Surgery, Fellow
• American Academy of Pediatrics, Specialty Fellow
• American College of Cardiology, Fellow
• American College of Chest Physicians, Fellow
• American College of Surgeons, Fellow
• American Heart Association
• Council on Cardio-Thoracic and Vascular Surgery, Inaugural Fellow
• American Society of Transplant Surgeons
• American Surgical Association
• Association for Academic Surgery
• Congenital Heart Surgeons Society
• College of Physicians of Philadelphia, Fellow
• David C. Sabiston, Jr. Society
• Extracorporeal Life Support Organization
• Society of Thoracic Surgeons
• Southern Thoracic Surgical Society
• Society for Thoracic Surgical Education
• Society for Vascular Surgery

• International Society for Cardiovascular Surgery
• International Society for Heart and Lung Transplantation
• International Pediatric Transplant Association (IPTA)
• Corresponding Member - Argentine Society of Cardiology
  (Sociedad Argentina de Cardiologia)
• International Member - European Association for Cardio-Thoracic Surgery

• Missouri American Heart Association Grant-in Aid 1984-85
  Balloon Counterpulsation for Right Ventricular Failure

1. Finger I, Fishbein GP, Spray TL, White R, Dilworth L: Radio-immunoassay of paramecium surface antigens. Immunology 22:1051, 1972.
2. Waugh RA, Spray TL, Sommer JR: Fenestrations of sarcoplasmic reticulum. Delineation by lanthanum acting as a fortuitous tracer and in situ negative stain. J of Cell Biology 59(1):254-260, 1973.
3. Spray TL, Waugh RA, Sommer JR: Peripheral couplings in adult vertebrate skeletal muscle. Anatomical observations and functional implications. J of Cell Biology 62(1):223-227, 1974.
4. Roberts WC, Spray TL: Pericardial heart disease: A study of its causes, consequences, and morphologic features. Cardiovascular Clinics 7(3):11-65, 1976.
5. Breyer RH, Spray TL, Kastl DG, Roberts WC: Histologic changes in saphenous vein aorta-coronary bypass grafts. The effect of the angle of the aortic anastomosis. J Thorac Cardiovasc Surg 72(6):916-924, 1976.
6. Spray TL, Roberts WC: Tension on coronary bypass conduits. A neglected cause of real or potential obstruction of saphenous vein grafts. J Thorac Cardiovasc Surg 72(2):282-287, 1976.
7. Spray TL, Watson DC, Robert WC: Morphology of canine hearts after 24 hours' preservation and orthotopic transplantation. J Thorac Cardiovasc Surg 73(6):880-886, 1977.
8. Spray TL, Robert WC: Changes in saphenous veins used as aortocoronary bypass grafts. American Heart Journal 94(4):500-516, 1977.
9. Spray TL, Roberts WC: Status of the grafts and the native coronary arteries proximal and distal to coronary anastomotic sites of aortocoronary bypass grafts. Circulation 55(5):741-74, 1977.
10. Roberts WC, Spray TL: Pericardial heart disease. Current Problems in Cardiology 2(3):1-71, 1977.
11. Lachman AS, Spray TL, Kerwin DM, Shugoll GI, Roberts WC: Medial calcinosis of Mönckeberg. A review of the problem and a description of a patient with involvement of peripheral, visceral and coronary arteries. Am J Med 63(4):615-622, 1977.
12. Spray TL, Roberts WC: Structural changes in porcine xenografts used as substitute cardiac valves. Gross and histologic observations in 51 glutaraldehyde-preserved Hancock valves in 41 patients. Am J Cardiol 40(3):319-330, 1977.
13. Muna WF, Spray TL, Morrow AG, Roberts WC: Aortic dissection after aortic valve replacement in patients with valvular aortic stenosis. J Thorac Cardiovasc Surg 74(1):65-69, 1977.
14. Spray TL, Derkac WM, Morrow AG, Robert WC: Ventricular pseudoaneurysm after transaortic septal myotomy for hypertrophic subaortic stenosis. Ann Thorac Surg 26(3):269-273, 1978.
15. Ferrans VJ, Spray TL, Billingham ME, Roberts WC: Structural changes in glutaraldehyde-treated porcine heterografts used as substitute cardiac valves. Transmission and scanning electron microscopic observations in 12 patients. Am J Cardiol 41(7):1159-1184, 1978.
16. Breyer RH, Arnett EN, Spray TL, Roberts WC: Prosthetic-valve endocarditis due to Listeria monocytogenes. Am J Clin Pathol 69(2):186-187, 1978.
17. Spray TL, Roberts WC: Structural changes in Hancock porcine xenograft cardiac valve bioprostheses. Advances In Cardiology (22)241-251, 1978.
18. Spray TL, Maron BJ, Morrow AG, Epstein SE, Roberts WC: A discussion on hypertrophic cardiomyopathy. Am Heart J 95(4):511-520, 1978.
19. Ferrans VJ, Boyce SW, Billingham ME, Spray TL, Roberts WC: Infection of glutaraldehyde-preserved porcine valve heterografts. Am J Cardiol 43(6):1123-1136, 1979.
20. Jones RN, Peyton RB, Sabina RL, Swain JL, Holmes EW, Spray TL, Van Trigt P, Wechsler AS: Transmural gradient in high-energy phosphate content in patients with coronary artery disease. Ann Thorac Surg 32(6):546-553, 1981.
21. Pasque MK, Pellom GL, Van Trigt P, Spray TL, Frame JR, Freedman BM, Deaton DW, Fagraeus L, Wechsler AS, Christian CC, Neglen P, Davis GF: Ribose selectively enhances systolic but not diastolic recovery following ischemia. Surgical Forum 33312-314, 1982.
22. Van Tright P, Spray TL, Pasque MK, Peyton RB, Pellom GL, Christian CM, Fagraeus L, Wechsler AS: The effect of PEEP on left ventricular diastolic dimensions and systolic performance following myocardial revascularization. Ann Thorac Surg 33(6):585-592, 1982.
23. Phillips HR, Spray TL, Lowe JE, Morris KG, Wechsler AS: Subvalvular thrombotic obstruction of an aortic porcine heterograft. Chest 81(6):756-758, 1982.
24. Sink JD, Spray TL, Rankin JS: Hemophilus influenzae pericarditis. Clinical Cardiology 5(10):547-549, 1982.
25. Pasque MK, Spray TL, Pellom GL, Van Trigt P, Peyton RB, Currie WD, Wechsler AS: Ribose-enhanced myocardial recovery following ischemia in the isolated rat heart. J Thorac Cardiovasc Surg 83(3):390-398, 1982.
26. Roberts WC, Spray TL, Shemin RJ, Maron BJ: Crisscrossed atrioventricular valves and survival for 55 years. Am J Cardiol 50(6):1436-1439, 1982.
27. Van Trigt P, Christian C, Fagraeus L, Peyton RB, Jones RN, Spray TL, Pasque MK, Wechsler AÍ, Pellom GL: The mechanism of halothane-induced myocardial depression. Altered diastolic mechanics versus impaired contractility. J Thorac Cardiovasc Surg 85(6):832-838, 1983.
28. Van Trigt P, Spray TL, Pasque MK, Peyton RB, Pellom GL, Fagreus L, Christian C, Wechsler AS: The influence of time on the response to Dopamine after coronary artery bypass grafting: assessment of left ventricular performance and contractility using pressure/dimension analyses. Ann Thorac Surg 35(1):3-13, 1983.
29. Van Trigt P, Spray TL, Pasque MK, Peyton RB, Pellom GL, Wechsler AS: The comparative effects of dopamine versus Dobutamine on ventricular mechanics after coronary artery bypass grafting: a pressure-dimension analysis. Circulation 70(3):7, 1983.
30. Van Trigt, P, Spray TL, Pasque MK, Peyton RB, Pellom GL, Wechsler AS: Myocardial depression by anesthetic agents (halothane, enflurane and nitrous oxide): quantitation based on end-systolic pressure-dimension relations. Am J Cardiol 53(1):243-247, 1984.
31. Van Trigt P, Spray TL, Pasque MK, Peyton RB, Wechsler AS: Anesthesia-induced myocardial depression: quantitation of effects on systolic and diastolic function. Surgery 96(2):368-374, 1984.
32. Canter CE, Martin TC, Spray TL, Weldon CS, Strauss AW: Scimitar syndrome in childhood. Am Cardiol 58(7):652-654, 1986.
33. Bolman RM, Spray TL, Cox JL, Kouchoukos NT, Cance C, Saffitz J, Genton RE, Eisen H: Heart transplantation in patients requiring preoperative mechanical support. J Heart Transplant 6(5):273-280, 1987.
34. Barzilai B, Vered Z, Spray TL, Courtois M, Perez J: Valvular regurgitation: intraoperative assessment with epicardial and transesophageal contrast, Doppler and color flow mapping. Dynamic Cardiaovasc Imaging 1(2):113-116, 1987.
35. Laschinger JC, Vannier MW, Gutierrez F, Gronemeyer S, Weldon CS, Spray TL, Cox JL: Preoperative three-dimensional reconstruction of the heart and great vessels in patients with congenital heart disease. Technique and initial results. J Thorac Cardiovasc Surg 96(3):464-473, 1988.
36. Bolman RM, Cance C, Spray TL, Genton R, Weiss C, Saffitz J, Eisen H: The changing face of cardiac transplantation: the Washington University Program, 1985-1987. Ann Thorac Surg 45(2):192-197, 1988.
37. Griffin ML, Hernandez A, Martin TC, Goldring D, Bolman RM, Spray TL, Strauss AW: Dilated cardiomyopathy in infants and children. J Am Coll of Cardiol 11(1):139-144, 1988.
38. Canter CE, Gutierrez FR, Spray TL, Martin TC: Diagnosis of anomalous left coronary artery from the pulmonary trunk by color Doppler echocardiography. Am Heart J 116(3):885-886, 1988.
39. Bolman RM, Cox JL, Marshall W, Kouchoukos NT, Spray TL, Cance C, Genton RE, Saffitz J: Circulatory support with a centrifugal pump as a bridge to cardiac transplantation. Ann Thorac Surg 47(1):108-112, 1989.
40. Weinhaus L, Canter C, Noetzel M, McAlister W, Spray TL: Extracorporeal membrane oxygenation for circulatory support after repair of congenital heart defects. Ann Thorac Surg 48(2):206-212, 1989.
41. Canter CE, Sekarski DC, Martin TC, Gutierrez FR, Spray TL: Intraoperative evaluation of atrioventricular septal defect repair by color flow mapping echocardiography. Ann of Thorac Surg 48(4):544-550, 1989.
42. Garrett HE, Spray TL: Accessory mitral valve tissue: an increasingly recognized cause of left ventricular outflow tract obstruction. J Cardiovasc Surg 31(2):225-230, 1990.
43. Cohen ML, Spray TL, Gutierrez F, Barzilai B, Bauwens D: Congenital tricuspid valve stenosis with atrial septal defect and left anterior fascicular block. Clin Cardiol 137:497-499, 1990.
44. Braunlin EA, Canter CE, Olivari MT, Ring WS, Spray TL, Bolman RM: Rejection and infection after pediatric cardiac transplantation. Ann Thorac Surg 49(3):385-390, 1990.
45. Braunlin EA, Canter CE, Gutierrez FR, Olivari MT, Bolman RM, Ring WS, Spray TL, Hunter DW, Titus JL: Coronary artery disease in pediatric cardiac transplant recipients receiving triple drug immunosuppression. Circulation 3(3):303-309, 1991.
46. Canter CE, Gutierrez FR, Molina P, Hartmann AF, Spray TL: Noninvasive diagnosis of right-sided extracardiac conduit obstruction by combined magnetic resonance imaging and continuous-wave Doppler echocardiography. J Thorac Cardiovasc Surg 104(4):724-731, 1991.
47. Sommer JR, Bossen E, Dalen H, Dolber P, High T, Spray TL, Jewett PH, Johnson EA, Junker J, Spach MS, Leonard S, Nassar R, Scherer B: To excite a heart: A bird's view. Acta Physiologica Scandinavica 142(87):5-21, 1991.
48. Canter CE, Appleton RS, Saffitz JE, Bologna S, Miller L, Pennington DG, Spray TL: Surveillance for rejection by echocardiographically guided endomyocardial biopsy in the infant heart transplant recipient. Circulation 3:310-315, 1991.
49. Van Meter CH, Lusk RM, Muntz H, Spray TL: Tracheoplasty for congenital long-segment intrathoracic tracheal stenosis. American Surgeon 57(3):157-160, 1991.
50. Spray TL, Mallory GB, Canter CE, Huddleston CB, Kaiser LR: Pediatric lung transplantation for pulmonary hypertension and congenital heart disease. Ann Thorac Surg 54:216-225, 1992.
51. Barzilai B, Davila-Roman VG, Eaton M, Rosenbloom M. Spray TL, Wareing TH, Cox JL, Kouchoukos NT: Transesophageal echocardiography predicts successful withdrawal of ventricular assist devices. J Thorac Cardiovasc Surg 104:1410-1416, 1992.
52. Creswell LL, Rosenbloom M, Cox JL, Ferguson, Sr TB, Kouchoukos NT, Spray TL, Pasque MK, Wareing TH, Huddleston CB, Ferguson, Jr. TB: Intraaortic balloon counterpulsation: patterns of usage and outcome in cardiac surgery patients. Ann Thorac Surg 54(1):11-20, 1992.
53. Hunkeler NM, Canter CE, Donze A, Spray TL: Extracorporeal life support in cyanotic congenital heart disease before cardiovascular operation. Am J Cardiol 69:790-793, 1992.
54. Raisher BD, Gran JW, Martin, TC, Strauss AW, Spray TL: Complete repair of total anomalous pulmonary venous connection in infancy. J Thorac Cardiovasc Surg 104:443-448, 1992.
55. Hardin JT, Muskett AD, Canter CE, Martin TC, Spray TL: Primary surgical closure of large ventricular septal defects in small infants. Ann Thorac Surg 53:397-401, 1992.
56. Balzer D, Spray TL, Canter CE, Strauss AW: Endarteritis associated with a clinically silent patent ductus arteriosus. Am Heart J 125(4):1192-3, 1993.
57. Johnson MC, Canter CE, Strauss AW, Spray TL: Surgical repair of coarctation of the aorta in infancy: Comparison of surgical and balloon angioplasty. Am Heart J 125(2 PT 1):464-8, 1993.
58. Canter CE, Moorhead S, Saffitz JE, Huddleston CB, Spray TL: Steroid withdrawal in the pediatric heart transplant recipient initially treated with triple immunosuppression. Am J Cardiol 13:74-80, 1993.
59. Spray TL, Huddleston CB, Canter CE: Technique of transplantation for hypoplastic left heart syndrome with left superior vena cava. Ann Thorac Surg 55(3):779-781, 1993.
60. Canter CE, Moorhead S, Huddleston CB, Spray TL: Restrictive atrial septal communication as a determinant of outcome of cardiac transplantation for hypoplastic left heart syndrome. Circulation 88(2):456-460, 1993.
61. Huddleston CB, Spray TL: Damus-Kaye-Stansel With Cavopulmonary Connection For Single Ventricle and Subaortic Obstruction. Ann Thorac Surg 55(2):339-346, 1993.
62. Spray TL: Projections for Pediatric Heart/Lung and Lung Transplantation. J Heart Lung Transplant S12:337-43, 1993.
63. Canter CE, Saffitz JE, Moorhead S, Gutierrez FR, Bolman RM, Spray TL: Early results after pediatric cardiac transplantation with triple immunosuppression therapy. Am J Cardiol, 71:971-975, 1993.
64. Kouchoukos NT, Davila-Roman VG, Spray TL, Murphy SF, Perrillo JB: Aortic Root Replacement With Pulmonary Autograft for Aortic Valve Disease. N Engl J Med 330:1-6, 1994.
65. Bejarano PA, Dehner LP, Wick MR, Huddleton CB, Spray TL: Isolated Lung Transplantation in Children: Pathologic Diagnosis and Incidence of Pulmonary Complications. Human Pathology 25(11):1179-1184, 1994.
66. Spray TL, Mallory GB, Canter CE, Huddleston CB: Pediatric Lung Transplantation: Indications, Techniques and Early Results. J Thorac Cardiovasc Surg 107(4):990-1000, 1994.
67. Grant JW, Canter CE, Spray TL, Landt Y, Saffitz JE, Ladenson JH, and Jaffe AS: Elevated Donor Cardiac Troponin I: A Marker of Acute Graft Failure in Infant Heart Recipients. Circulation, 90:2618-2621, 1994.
68. Lynch BJ, Gkuise TA, Canter CE, Spray TL: Neurologic complications of pediatric heart transplantation. Arch Pediatr Adolesc Med 148:973-979, 1994.
69. Tweddell JS, Canter CE, Bridges ND, Moorhead S, Huddleston CB, Spray TL: Predictors of Operative Mortality and Morbidity After Infant Heart Transplantation. Ann Thorac Surg 58:972-977, 1994.
70. Spray TL: Transplantation of the Heart and Lungs in Children. Annu.Rev.Med 45:139-48 1994.
71. Schlesinger AE, Mendeloff E, Sharkey AM, Spray TL: MR of right aortic arch with mirror-image branching and a left ligamentum arteriosum: an unusual cause of a vascular ring. Pediatr Radiol 25(6):455-457, 1995.
72. Bridges ND, Mallory GB, Huddleston CB, Canter CE, Sweet S and Spray TL: Lung Transplantation in Children and Young Adults with Cardiovascular Disease. Ann Thorac Surg 59:813-21, 1995.
73. Jaquiss RDB, Huddleston CB, Spray TL: Use of Aprotinin in Lung Transplantation. J Heart Lung Transplant Vol 14 #2:302-307, 1995.
74. Johnson MC, Strauss AW, Dowton SB, Spray TL, Huddleston CB, Wood MK, Slaugh RA, Watson MS. Deletion Within Chromosome 22 is Common in Patients with Absent Pulmonary Valve Syndrome. Am J Cardiol 76:66-69, 1995.
75. Johnson MC, Watson MS, Strauss AW, Spray TL. Anomalous Origin of Right Pulmonary Artery From the Aorta and CATCH 22 Syndrome. Ann Thorac Surg 60:681-3, 1995.
76. Mendeloff EN, Spray TL, Huddleston CB, Bridges ND, Canter CB, Mallory GB, Jr: Lung Transplantation for Congenital Pulmonary Vein Stenosis. Ann Thorac Surg 60:903-7, 1995.
77. Balzer DT, Moorhead S, Saffitz JE, Huddleston CB, Spray TL, Canter CE: Utility of Surveillance Biopsies in Infant Heart Transplant Recipients. J Heart Lung Transplant 14:1095-1101, 1995.
78. Jacquiss RDB, Lusk RP, Spray TL. Huddleston CB. Repair of Long-segment Tracheal Stenosis in Infancy. J Thorac Cardiovasc Surg 110:1504-12, 1995.
79. Bromberg BI, Mazziotti MV, Canter CE, Spray TL, Strauss AW, Foglia RP: Recognition and Management of Nonpenetrating Cardiac Trauma in Children. J Pediatr 128(4):536-41, 1996.
80. Oski J, Canter CE, Spray TL, Kan JS, Cameron DE, Murphy AM. Embolic stroke after ligation of the pulmonary artery in patients with functional single ventricle. Am Heart J 132(4):836-40, 1996.
81. Bridges ND, Gaynor JW, Spray TL. Outcome of Children with Pulmonary Hypertension Referred for Lung or Heart and Lung Transplantation. Transplantation 62:1824-1828 1996.
82. Santos-Ocampo SD, Sekarski TJ, Saffitz JE, Bridges ND, Huddleston CB, Spray TL, Canter CE: Echocardiographic Characteristics of Biopsy-Proven Cellular Rejection in Infant Heart Transplant Recipients. J Heart Lung Transplant 15:25-34, 1996.
83. Bridges ND, Mallory GB, Huddleston CB, Canter CE, Spray TL: Lung Transplantation in Infancy and Early Childhood. J Heart Lung Transplant 15:895-902, 1996.
84. Koutlas TC, Wernovsky G, Bridges ND, Suh EJ, Godinez RI, Nicolson SC, Spray TL, Gaynor JW: Orthotopic heart transplantation for Kawasaki disease after rupture of a giant coronary artery aneurysm. J Thorac Cardiovasc Surg 113:217-18, 1997.
85. Canter CE, Spray TL, Huddleston CB, Mendeloff E: Intraoperative evaluation of atrioventricular septal defect repair by color flow mapping echocardiography. Ann Thorac Surg, 63: 592-3 1997 (Updated from 48(4):544-550, 1989).
86. Hamvas A, Nogee LM, Mallory GB, Spray TL, Huddleston CB, August A, Dehner LP, deMello DE, Moxley M, Nelson R, Cole FS, Colten HR: Lung Transplantation for Treatment of Surfactant Protein B Deficiency. J Pediatr 13(2):231-9, 1997.
87. Koutlas TC, Bridges, ND, Gaynor JW, Nicolson SC, Steven JM, Spray TL: Pediatric Lung Transplantation: Are There Surgical Contraindications? Transplantation Vol 63:269-274, 1997.
88. Koutlas TC, Gaynor JW, Nicolson SC, Steven, JM, Wernovsky G, Spray TL: Modified Ultrafiltration Reduces Postoperative Morbidity After Cavopulmonary Connection. Ann Thorac Surg;64: 37-43 1997.
89. Sweet SC, Spray TL, Huddleston CB, Mendeloff E, Canter CB, Balzer DT, Bridges ND, Cohen AH, Mallory GB. Pediatric Lung Transplantation at St. Louis Children's Hospital 1990-1995. Am J Respir Crit Care Med 155(3):1027-35, 1997.
90. Rychik J, Fogel MA, Donofrio MT, Goldmuntz E, Cohen MS, Spray TL, Jacobs ML: Comparison of Patterns of Pulmonary Venous Blood Flow in the Functional Single Ventricle Heart and Operative Aorto-pulmonary Shunt - vs - Superior Cavo-Pulmonary Shunt. Am J Cardiol 1997;80:922-926.
91. Gaynor JW, Spray TL. Cardiac Transplantation in Neonates and Infants. Cardiology in Review. Vol. 6 No.1: 37-44, 1998.
92. Koutlas TC, Wernovsky G, Slack M, Weinberg PM, Spray TL: Surgical Management of Tricuspid Atresia and Anomalous Left Brachiocephalic Vein. Ann Thorac Surg 1998;65:1770-2.
93. Donofrio MT, Jacobs ML, Spray TL, Rychik J: Acute Changes in Preload, Afterload and Systolic Function after Superior Cavopulmonary Connection. Ann Thorac Surg 1998;65:503-8.
94. Spray TL: Use of Aprotinin in Pediatric Organ Transplantation. Ann Thorac Surg 1998; 65:S71-3.
95. Jones E, Feuerstein IM, Tucker E, Summers RM, Spray TL, Hoeg JM. Aortic Hypoplasia in Homozygous Hyperchoesterolemia. Amer J Cardiol 1998;81:1242-43.
96. Summers RM, Andrasko-Bourgeois J, Feuerstein IM, Hill SC, Jones EC, Busse MK, Wise B, Bove KE, Rishforth BA, Tucker E, Spray, TL, Hoeg, JM. Evaluation of the aortic root by MRI: Insights from patients with homozygous familial hypercholesterolemia. Circulation 1998, 98:509-518.
97. Gaynor JW, Bridges ND, Clark BJ, Spray TL: Update on lung transplantation in children. Curr Opin Pediatr 1998, 10:256-261.
98. Cohen MI, Wernovsky G, Vetter VL, Wieand TS, Gaynor JW, Jacobs MJ, Spray TL, Rhodes LA. Sinus node dysfunction after systematically staged Fontan. Circulation 1998;98:II352-II359.
99. Rychik J, Levy H, Gaynor JW, DeCampli WM, Spray TL: Outcome after operations for pulmonary atresia with intact ventricular septum. J Thorac Cardiovasc Surg 1998;116:924-31.
100. Bockoven JR, Wernovsky G, Vetter VL, Wieand TS, Spray TL, Rhodes LA: Peri-operative Conduction and Rhythm Disturbances after the Ross Procedure in Children and Young Adults. Ann Thorac Surg 1998 66(4):1383-8.
101. Vitvitsky EV, Griffin JP, Collins MH, Spray TL, Gaynor JW. Increased Pulmonary Blood Flow Produces Endothelial Cell Dysfunction in Neonatal Swine. Ann Thorac Surg 66:1372-1377, 1998.
102. Bridges ND, Spray TL, Collins M, Bowles NE, Towbin JA. Adenovirus Infection in the Lung Results in Graft Failure after Pediatric Lung Transplantation. J Thorac Cardiovasc Surg 1998 116(4):617-23.
103. Fogel MA, Weinberg PM, Rychik J, Hubbard A, Jacobs M, Spray TL, Haselgrove J. Caval Contribution to Flow in the Branch Pulmonary Arteries of Fontan Patients Using a Novel Application of Magnetic Resonance Presaturation Pulse. Circulation 1999, 99(9):1215-21.
104. Mythe WR, Gorman RC, DeCampli WM, Spray TL, Kaiser LR, Acker MA. Management of Exsanguinating Hemoptysis During Cardiopulmonary Bypass. Ann Thorac Surg 1999;67:1288-91.
105. Mott AR, Spray TL, Bridges ND: Heart/Single-Lung Transplant for a “Failed Fontan” with Pulmonary A-V Malformation. Ann Thorac Surg 1999;67:841-3.
106. McLaughlin RB, Wetmore RF, Tavill MA, Gaynor JW, Spray TL Vascular Anomalies causing Tracheobronchial Compression: A review of clinical presentation, diagnostic evaluation, and post-surgical outcome. Laryngoscope 1999, 109:312-319.
107. Gaynor JW, Collins MH, Rychik J, Spray TL: Long-term outcome of infants with single ventricle and total anomalous pulmonary venous connection. J Thorac Cardiovasc Surg 1999;117:506-14.
108. McDonnell BE, Raff GW, Gaynor JW, Rychik J, Godinez RI, DeCampli WD, Spray TL. Outcome Following Repair of Tetralogy of Fallot with Absent Pulmonary Valve. Ann Thorac Surg 1999;67:1391-6.
109. Lee HR, Montenegro LM, Nicolson SC, Gaynor JW, Spray TL, Rychik J: Usefulness of Intra-operative Transesophageal Echocardiography in Predicting the Degree of Mitral Regurgitation Secondary to Atrioventricular Defect in Children. Am J Cardiol 1999;83:750-3.
110. Ro PS, Spray TL, Bridges ND: Outcome of Infants Listed for Lung or Heart/Lung transplantation. J Heart Lung Transplant 1999 18(12):1232-7.
111. Rychik J, Rome JJ, Collins MH, DeCampli WM, Spray TL: The hypoplastic left heart syndrome with Intact Atrial Septum: Atrial Morphology, Pulmonary Vascular Histopathology and Outcome. J Am Coll Cardiol 1999;34:554-60.
112. Ramesh V, Gaynor JW, Shah MJ, Wieand TS, Spray TL, Vetter VL, Rhodes LA: Comparison of Left and Right Atrial Epicardial Pacing in Patients with Congenital Heart Disease. Ann ThoracSurg 1999;68:2314-9.
113. Berry GT, Bridges ND, Nathanson K, Kaplan P, Clancy RR, Lichtenstein GR, Spray TL: Successful use of alternate waste nitrogen agents and hemodialysis in a patient with hyperammonemic coma following heart-lung transplantation. Archives of Neurology 1999 56(4):481-4.
114. Weinstein S, Gaynor JW, Bridges ND, Wernovsky G, Montenegro LM, Godinez RI, Spray TL: Early Survival of Infants Weighing 2.5 Kilograms or Less Undergoing First-Stage Reconstruction for Hypoplastic Left Heart Syndrome. Circulation 1999;100[suppl II]:II-167-II-170.
115. Marino BS, Wernovsky G, Rychik J Bockoven JR, Godinez RI, Spray TL: Early Results of the Ross Procedure in Simple and Complex Left Heart Disease. Circulation 1999 ;100[suppl II]:II-162-II166).
116. Rychik J, Bush DM, Spray TL, Gaynor JW, Wernovsky G. Assessment of pulmonary-to-systemic flow ratio after first stage palliation for hypoplastic left heart syndrome: Development of a new index using Doppler echocardiography. J Thorac Cardiovasc Surg 2000;120:81-87.
117. DiRusso GB, Clark BJ, Bridges ND, Godinez RI, Paridon SM, Spray TL, Gaynor JW: Prolonged Extracorporeal Membrane Oxygenation as a Bridge to Cardiac Transplantation. Ann Thorac Surg 2000;69:925-7.
118. Hoffman TM, Spray TL, Gaynor JW, Clark BJ, Bridges ND. Survival after acute graft failure in pediatric thoracic organ transplant recipients. Pediatr Transplant 2000;4:112-117.
119. Clancy RR, McGaurn SA, Wernovsky G, Spray TL, Norwood WI, Jacobs ML, Murphy JD, Gaynor JW, Goin JE: Pre-Surgical Risk-of-Death Prediction Model in Neonatal Repair of Congenital Heart Disease. J Thorac Cardiovasc Surg 2000;119:347-357.
120. McElhinney DB, Paridon S, Spray TL: Aortopulmonary Window Associated with Complete Atrioventricular Septal Defect. J Thorac Cardiovasc Surg 2000;119:1284-5.
121. WR, Bridges ND, Gaynor JW, Nicolson SC, Clark BJ, Spray TL. Bilateral Sequential Lung Transplant for Ectodermal Dysplasia. Ann Thorac Surg 2000;70:654-6.
122. Cohen MI, Bush DM, Ferry RJ Jr., Spray TL, Moshang T Jr., Wernovsky G, Vetter VL: Somatic Growth Failure After Fontan Operation. Cardiol Young 2000;10:447-457.
123. Cohen MI, Bridges ND, Gaynor JW, Hoffman TM, Wernovsky G, Vetter VL, Spray TL, Rhodes LA: Modifications to the Cavopulmonary Anastomosis Do Not Eliminate Sinus Node Dysfunction. J Thorac Cardiovasc Surg 2000;120:891-901.
124. Yang S-G, Novello R, Nicolson S, Steven J, Gaynor JW: Spray TL, Rychik J: Evaluation of ventricular septal defect repair using intraoperative transesophageal echocardiography: Frequency and significance of residual defects in infants and children. Echocardiography 2000;17:681-4.
125. Mahle WT, Spray TL, Wernovsky G, Gaynor JW, Clark BJ: Survival After Reconstructive Surgery for Hypoplastic Left Heart Syndrome: A 15-year Experience from a Single Institution. Circulation 2000;102[suppl III]:III-136-III-141.
126. Raff, GW, Gaynor, JW, Weinberg P, Spray TL, Gleason M. Membranous subpulmonic stenosis associated with ventricular septal defect and aortic insufficiency. J Am Soc Echocardiogr 2000;13:58-60.
127. Gaynor JW, Wernovsky G, Rychik J, Rome JJ, DeCampli WM, Spray TL: Outcome Following Single-Stage Repair of Coarctation with Ventricular Septal Defect. The Eur J CardioThorac Surg 2000;18:62-67.
128. McElhinney DB, Hedrick HL, Bush DM, Pereira GR, Stafford PW, Gaynor JW, Spray TL, Wernovsky G: Necrotizing Enterocolitis in Neonates with Congenital Heart Disease: Risk Factors and Outcomes. Pediatrics 2000;106:1080-87.
129. Gaynor JW, Weinberg P, Spray TL. Congenital heart surgery nomenclature and database project: Systemic venous anomalies. Ann Thorac Surg 2000;69:S70-S76.
130. Gaynor JW, Bridges ND, Spray TL. Congenital heart surgery nomenclature and database project: End stage lung disease. Ann Thorac Surg 2000;69:S343-S357.
131. Mott AR, Spray TL, Gaynor JW, Godinez RI, Nicolson SC, Steven JM, DeCampli WM, Schears GJ, Wernovsky G. Improved Results with Cavopulmonary Connections for Functional Single Ventricle. Cardiol Young 2001;11:3-11.
132. Mahle WT, Gaynor JW, Spray TL: Atrioventricular Valve Replacement in Patients with Single Ventricle. Ann Thorac Surg 2001;72:182-6.
133. Collins MH, Montone KT, Leahey AM, Hodinka RL, Salhany KE, Rorke LB, Clark BJ, Duhaime A, Spray TL, Tomaszewski JE. Metachronous Epstein-Barr virus-related smooth muscle tumors in a child following heart transplant: Report of a case and review of the literature. J Pediatr Surg 2001;36(9):1452-5.
134. Mahle WT, Spray TL, Gaynor JW, Clark BJ: Unexpected Death after Reconstructive Surgery for Hypoplastic Left Heart Syndrome. Ann Thorac Surg 2001;71:61-5.
135. Kurth DC, Steven JM, Montenegro LM, Nicolson SC, Gaynor JW, Spray TL: Cerebral Oxygen Saturation Before Congenital Heart Surgery. Ann Thorac Surg 2001;72:187-92.
136. Mahle WT, Cohen MS, Spray TL, Rychik J: Atrioventricular Valve Regurgitation in Patients with Single Ventricle: Impact of the Bidirectional Cavopulmonary Anastomosis. Ann Thorac Surg 2001;72:831-5.
137. Wernovsky G, Rubenstein SD, Spray TL: Cardiac Surgery in the Low-Birth Weight Neonate: New Approaches. Clinics in Perinatology 2000 Vol 28, No 1, March 2001.
138. McElhinney DB, Hoydu AK, Gaynor JW, Spray TL, Goldmuntz E, Weinberg PM. Patterns of Right Aortic Arch and Mirror-Image Branching of the Brachiocephalic Vessels Without Intracardiac Anomalies. Pediatr Cardiol 22:285-291, 2001.
139. Heath JA, Kurland G, Spray TL, Kernan NA, Small TN, Brochstein JA, Gillio AP, Boklan J, O'Reilly RJ, Boulad F. Lung transplantation after allogeneic marrow transplantation in pediatric patients: The Memorial Sloan-Kettering Experience. Transplantation December 2001 Vol 72 #12:1986-90.
140. Gaynor JW, O'Brien JE Jr., Rychik J, Sanchez GR, DeCampli WM, Spray TL: Outcome following tricuspid valve detachment for ventricular septal defects closure. Eur J CardioThorac Surg 2001;19:279-282.
141. Clancy RR, McGaurn SA, Goin JE, Hirtz DG, Norwood WI, Gaynor JW, Jacobs ML, Wernovsky G, Mahle WT, Murphy JD, Nicolson SC, Steven JM, Spray TL: Allopurinol Neurocardiac Protection Trial in Infants Undergoing Heart Surgery Using Deep Hypothermic Circulatory Arrest. Pediatrics July 2001 108 #(1):61-70.
142. Coon PD, Rychik J, Novello RT, Ro P, Gaynor JW, Spray TL: Thrombus Formation after the Fontan Operation. Ann Thorac Surg 2001;71:1990-4.
143. Mahle WT, Rychik J, Gaynor JW, Spray TL, Rome JJ: Restrictive Inter-atrial Communication Following Reconstructive Surgery for Hypoplastic Left Heart Syndrome. Am J Cardiol 2001;88:1454-57.
144. Ro PS, Bush DM, Kramer SS, Mahboubi S, Spray TL: Airway Growth after Pediatric Lung Transplantation. J Heart Lung Transplant 2001;20:619-624.
145. McElhinney DB, Yang SG, Hogarty AN, Rychik J, Gleason MM, Zachary CH, Rome JJ, Karl TR, DeCampli WM, Spray TL, Gaynor JW. Recurrent arch obstruction after repair of isolated coarctation of the aorta in neonates and young infants: Is low weight a risk factor? J Thorac Cardiovasc Surg 2001;122:883-90.
146. Cohen MI, Rhodes LA, Wernovsky G, Gaynor JW, Spray TL, Rychik J: Atrial Pacing: An Alternative Treatment for Protein-Losing Enteropathy Following the Fontan Operation. J Thorac Cardiovasc Surg 2001;121:582-3.
147. Hoffman TM, Gaynor JW, Bridges ND, Paridon SM, Spray TL: Aortic homograft interposition for management of complete tracheal anastomotic disruption after heart-lung transplantation. J Thorac Cardiovasc Surg 2001;121:587-8.
148. Cohen MI, Vetter VL, Wernovsky G, Bush DM, Gaynor JW, Iyer VR, Spray TL, Tanel RE, Rhodes LA: Epicardial pacemaker implantation and follow-up in patients with a single ventricle after the Fontan operation. J Thorac Cardiovasc Surg 2001;121:804-11.
149. Mahle WT, Cohen MS, Spray TL, Rychik J: Atrioventricular Valve Regurgitation in Patients with Single Ventricle: Impact of the Bidirectional Cavopulmonary Anastomosis. Ann Thorac Surg 2001;72(3):831-5.
150. Hoffman TM, Rhodes LA, Wieand TS, Spray TL, Bridges ND: Arrhythmias after pediatric lung transplantation. Pediatric Transplantation 2001;5:349-352.
151. Tabbutt S, Ramamoorthy C, Montenegro LM, Durning SM, Kurth DM, Steven JM, Godinez RI, Spray TL, Wernovsky G, Nicolson SC: Impact of Inspired Gas Mixtures on Pre-operative Infants with Hypoplastic Left heart Syndrome During Controlled Ventilation. Circulation 2001;104[suppl I]:I-159-I-164.
152. Kucharczuk JC, Cohen MI, Rhodes LA, Karl TR, Spray TL, Gaynor JW: Epicardial Atrial Pacemaker Lead Placement Following Multiple Cardiac Operations. Ann Thorac Surg 2001;71:2057-8.
153. McCrindle BW, Blackstone EH, Williams WG, Sittiwangkul R, Spray TL, Azakie A, Jonas RA: Are Outcomes of Surgical Versus Transcatheter Balloon Valvotomy Equivalent in Neonatal Critical Aortic Stenosis? Circulation 2001;104[suppl I]:I-152-I-158.
154. McElhinney DB, Carpentieri DF, Bridges ND, Clark BJ, Gaynor JW, Spray TL. Sarcoma of the mitral valve causing coronary arterial occlusion in children. Cardiol Young 2001 Sep;11(5):539-42.
155. Jones PL, Chapados R, Baldwin HS, Raff GW, Vitvitsky EV, Spray TL, Gaynor JW: Altered hemodynamics controls matrix metalloproteinase activity and tenascin-C expression in neonatal pig lung. Am J Physiol Lung Cell Mol Physiol 2002 282:L26-L35.
156. Mahle WT, Tavani F, Zimmerman RA, Nicolson SC, Galli K, Gaynor JW, Clancy RR, Montenegro LM, Spray TL, Chiavacci RM, Wernovsky G and Kurth CD. An MRI study of neurological injury before and after congenital heart surgery. Circulation 2002; 106 (Suppl I): I-109-I-114.
157. Hoffman TM, Wernovsky G, Atz AM, Bailey JM, Akbary A, Kocsis JF, Nelson DP, Change AC, Kulik TJ, Spray TL, Wessel DL: Prophylactic Intravenous Use of Milrinone After Cardiac Operation in Pediatrics (PRIMACORP) Study. Am Heart J 2002;143:15-21.
158. Jenkins KJ, Gauvreau K, Newburger JW, Spray T, Moller JH, Iezzoni LI: Consensus-Based Method for Risk Adjustment For Congenital Heart Surgery. J Thorac Cardiovasc Surg 2002;123:110-8.
159. Kirshbom PM, Bridges ND, Myung RJ, Gaynor JW, Clark BJ, Spray TL: Use of extracorporeal membrane oxygenation in pediatric thoracic organ transplantation. J Thorac Cardiovasc Surg 2002;123:130-136.
160. Gaynor JW, Bridges ND, Cohen MI, Mahle WT, DeCampli WM, Steven JM, Nicolson SC, Spray TL: Predictors of Outcomes After the Fontan Operation: Is Hypoplastic Left Heart Syndrome Still a Risk Factor? J Thorac Cardiovasc Surg 2002;123:237-45.
161. Cohen MS, Rychik J, Bush DM, Tian ZY, Howell LJ, Adzick NS, Flake AW, Johnson MP, Spray TL, Crombleholme TM. Influence of congenital heart disease on survival in children with congenital diaphragmatic hernia. J Pediatr 2002;141(1):25-30.
162. Hoffman TM, Bush DM, Wernovsky G, Cohen MI, Wieand TS, Gaynor JW, Spray TL, Rhodes LA: Postoperative Junctional Ectopic Tachycardia in Children: Incidence, Risk Factors and Treatment. Ann Thorac Surg 2002;74:1607-11.
163. Mahle WT, Tavani F, Zimmerman RA, Nicolson SC, Galli KK, Gaynor JW, Clancy RR, Montenegro LM, Spray TL, Chiavacci RM, Wernovsky G, Kurth D: An MRI Study of Neurological Injury Before and After Congenital Heart Surgery. Circulation 2002;106[suppl I]: I-109-I-114.
164. Gaynor JW, Mahle WT, Cohen MI, Ittenbach RF, Bridges ND, Wernovsky G, DeCampli WM, Karl TR, Steven JM, Nicolson SC, Spray TL: Risk Factors for Mortality after the Norwood Procedure. Eur J of Cardiothoracic Surg 2002; 22:82-89.
165. Hoffman TM, Wernovsky G, Wieand TS, Cohen MI, Jennings AC, Vetter VL, Gaynor JW, Spray TL, Rhodes LA: The Incidence of Arrhythmias in a Pediatric Intensive Care Unit. PediatrCardiol 2002, 23:598-604.
166. Fleenor JT, Hoffman TM, Bush DM, Paridon SM, Clark BJ, Spray TL, Bridges ND: Pneumatosis Intestinalis after Pediatric Thoracic Organ Transplantation. Pediatrics 2002;109(5):E78-8.
167. Kirshbom PM, Myung RJ, Gaynor JW, Ittenbach RF, Paridon SM, DeCampli WM, Karl TR, Spray TL: Preoperative Pulmonary Venous Obstruction Affects Long-term Outcome for Survivors of Total Anomalous Pulmonary Venous Connection Repair. Ann Thorac Surg 2002;74:1616-20.
168. Ashburn DA, McCrindle BW, Tchervenkov CI, Jacobs ML, Lofland GK, Bove EL, Spray TL, Williams WG, Blackstone EH (Congenital Heart Surgeons Society): Outcomes After the Norwood Operation in Neonates with Critical Aortic stenosis or Aortic Valve Atresia. J Thorac Cardiovasc Surg May 2003, 1070-1082.
169. Clancy RR, McGaurn SA, Wernovsky G, Gaynor JW, Spray TL, Norwood WI, Jacobs ML, Goin JE. Risk of Seizures in Survivors of Newborn Heart Surgery Using Deep Hypothermic Circulatory Arrest. Pediatrics 2003;111:592-601.
170. Colombani PM, Dunn SP, Harmon WE, Magee JC, McDiarmid SV, Spray TL: Pediatric Transplantation. Am J Transplant. 2003 Apr;3 Suppl 4:53-6.
171. Gaynor JW, Gerdes M, Zackai EH, Bernbaum J, Wernovsky G, Clancy RR, Newman MF, Saunders AM, Heagerty PJ, D’Agostino JA, McDonald-McGinn D, Nicolson SC, Spray TL, Jarvik GP. Apolipoprotein E Genotype and neurodevelopmental sequelae of infant cardiac surgery. J Thorac Cardiovasc Surg 2003; 126:1736-1745.
172. Gould DS, Montenegro LM, Gaynor JW, Lacy SP, Stephens P, Steven JM, Spray TL, and Nicolson SC. A comparison of on-site and off-site PDA ligation in premature infants. Pediatrics 2003; 112:1298-1301.
173. Hoffman TM, Wernovsky G, Atz AM, Kulik TJ, Nelson DP, Chang AC, Bailey JM, Akbary A, Kocsis JF, Kaczmarek R, Spray TL, Wessel DL. Efficacy and safety of milrinone in preventing low cardiac output syndrome in infants and children after corrective surgery for congenital heart disease. Circulation 2003;107(7)996-1002.
174. Huang J, Trinkaus K, Huddleston CB, Mendeloff EN, Spray TL, Canter CE. Risk Factors for Primary Graft Failure After Pediatric Cardiac Transplantation: The Importance of Recipient and Donor Characteristics. J Heart Lung Transplant 2004: 23; 716-722.
175. Galli KK, Zimmerman RA, Jarvik GP, Wernovsky G, Kuypers MK, Clancy RR, Montenegro LM, Mahle WT, Newman MF, Saunders AM, Nicolson SC, Spray TL and Gaynor JW. Periventricular Leukomalacia is common following Neonatal Cardiac Surgery. J Thorac Cardiovasc Surg 2004; 127:692-704.
176. Pastuszko P, Gruber PJ, Wernovsky G, Tanel RE, Rhodes LA, Nicolson SC, Spray TL, Gaynor JW. Thoratec Left Ventricular Assist Device as a Bridge to Recovery in a 27 kg Child. J Thorac Cardiovasc Surg 2004; 127:1203-1204.
177. Morris MC, Rodolfo IG, Portnoy JD, Tabbutt S, Ittenbach R, Hanna BD, Hoffman TM, Gaynor, JW, Connelly JT, Helfaer MA, Spray, TL and Wernovsky G. Extracorporeal Membrane Oxygenation ion 137 patients in a Pediatric Cardiac Intensive Care Unit. Crit Care Med 2004; 32:1061-1069.
178. Jacobs JP, Mavroudis C, Jacobs ML, Lacour-Gayet FG, Tchervenkov CI, Gaynor JW, Clarke DR, Spray TL, Maruszewski B, Stellin G, Elliott MJ, Dokholyan RS, Peterson ED. Lessons learned from the data analysis of the second harvest (1998-2001) of the society of Thoracic Surgeons (STS) Congenital Heart Surgery Database. EU J of Cardiothorac Surg 2004; 26:18-37.
179. Bailey JM, Hoffman TM, Wessel DL, Nelson DP, Atz AM, Chang AC, Kulik TJ, Spray TL, Akbary A, Miller RP, Wernovsky G. A population pharmacokinetic analysis of Milrinone in pediatric patients after cardiac surgery. J of Pharmacokinetics and Pharmacodynamics 2004; 31.
180. Licht D, Wang J, Silvestre DW, Nicolson SC, Montenegro, LM, Tabbutt, S, Durning SM, Shabbout, M, Shera DM, Gaynor JW, Spray TL, Clancy R,Zimmerman A, Dittre JA. Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects. J ThoracCardiovasc Surg 2004:28:841-849.
181. Cohen ML, Rhodes LA, Spray TL and Gaynor JW. Efficacy of Prophylactic Epicardial Pacing Leads in Children and Young Adults. Ann of Thorac Surg 2004; 78:197-203.
182. Lodge AJ, Rychik J, Nicolson SC, Ittenbach RF, Spray TL, Gaynor JW. Improving outcomes in functional single ventricle and total anomalous pulmonary venous connection. Ann Thorac Surg 2004; 78:1688-1695.
183. Zeltzer I, Rhodes L, Tanel RE, Vetter VL, Gaynor JW, Spray TL, and Cohen M. Post pericardiotomy syndrome following permanent pacemaker implantation in children and young adults. Ann Thorac Surg 2004; 78:1684-1687.
184. Shillingford A, Marino B, Ittenbach RF, Fedec A, Rychik J, Clancy RR, Spray TL, Gaynor JW and Wernovsky G. Microcephaly is Common in Neonates with Hypoplastic Left Heart Syndrome. Ped Cardiol 2005; 25: 581A.
185. Clancy RR, Sharif U, Ichord R, Spray TL, Nicolson SC, Tabbutt S, Wernovsky G, Gaynor JW. Electrographic neonatal seizures after infant heart surgery. Epilepsia 2005; 46(1):84-90.
186. Spray, TL. Data, dogma, or latest fashion? How scientific meetings and peer-reviewed Literature affect cardiac surgical practice. Cardiol Young; 2005;15 (Suppl.1):161-164.
187. Spray, TL, Jacobs, JP, Lacour-Gayet, FG, Jacobs, ML, Clarke, DR, Tchervenkow, CI, Gaynor, JW, Maruszewski, B, Stellin, G, Gould, J, Dokholyan, RS, Peterson, ED, Elliott, MJ, Mavroudis, Initial application in the STS congenital database of complexity adjustment to evaluate surgical case mix and results. Ann Thorac Surg 2005; 79:1635-490.
188. Spray, TL, Hoehn, KS, Wernovsky, G., Rychik, J, Gaynor, JW, Feudtner, C, and Nelson, RM. What factors are important to parents making decisions in neonatal research? Arch Dis Child Fetal Neonatal ED 2005; 90:267-269.
189. Spray, TL, Gaynor, JW, Kuypers, M, van Rossem, M, Wernovsky, G, Marino, B, Tabbutt, S., Nicolson, SC. Hemodynamic changes during modified ultrafiltration immediately following The first stage of the Norwood reconstruction. Cardiol Young 2005; 15(1):4-7.
190. Tabbutt, S, Dominguez, TE, Ravishankar, C, Marino, BS, Gruber, PJ, Wernovsky, G, Gaynor, JW, Nicolson, SC, Spray, TL. Outcomes following the Stage I reconstruction comparing right ventricle to pulmonary artery conduit with the modified Blalock Taussig shunt. Ann Thorac Surg 2005;80:1582-1591.
191. Hoehn SK, Wernovsky G, Rychik J, Tian ZY, Donaghue D, Alderfer MA, Gaynor JW, Kazak AE, Spray TL, Nelson RM. Assessment of parental stress and decision making in congenital heart diseases: prenatal versus postnatal diagnosis. Cardiol Young 2005; 15: 1844-1848.
192. Spray, TL and Landzberg, M. Pediatric cardiology and congenital heart disease. J Am Coll Cardiol 45:(11 Suppl B):9B-11B, 2005.
193. Meyer, DB and Spray, TL. Stage 1 – The Philadelphia approach. Op Tech TCVS 2005;10(4):299-312.
194. Schultz AH, Jarvik GP, Wernovsky G, Bernbaum J, Clancy RR, D’Agostino JD, Gerdes M, McDonald-Mcginn D, Nicolson SC, Spray TL, Zackai E and Gaynor JW. Effect of congenital heart disease on neurodevelopmental outcomes within multiple-gestation births. J Thorac Cardiovasc Surg 2005;130(6):1511-1516.
195. Jacobs JP, Maruszewski B, Lacour-Gayet FG, Jacobs ML, Clarke DR, Tchervenkov CI, Gaynor JW, Spray TL, Stellin G, Elliott MJ, Ebels T, Mavroudis C. Current Status of the European Association for Cardio-Thoracic Surgery and the Society of Thoracic Surgeons Congenital Heart Surgery Database. Ann Thorac Surg 2005; 80(6): 2278-2283; discussion 2283-4.
196. Spray, TL, Piel, DA, Khan, AR, Waibel, R, Birbach, M, Cohen, MS, Deutschman, CS, Gaynor, JW, Levy, RJ. Chronic hypoxemia increases myocardial cytochrome oxidase. J Thorac Cardiovasc Surg 2005;130(4):1101-1106.
197. Gaynor JW, Nicolson SC, Jarvik GP, Wernovsky G, Montenegro LM, Burnham NB, Hartman DM, Louie A, Spray TL, Clancy RR. Increasing Duration of deep hypothermic circulatory arrest is associated with an increased incidence of post-operative electroencephalographic seizures. J Thorac Cardiovasc Surg 2005;130(5):1278-1286.
198. Zeltser I, Menteer J, Gaynor JW, Spray TL, Clark BJ, Kreutzer J and Rome, JJ. Impact of re-coarctation following the Norwood operation on survival in the balloon angioplasty era. J Am Coll of Cardiol 45(11):1844-1848, 2005.
199. Kirshbom PM, Flynn TB, Clancy RR, Ittenbach RF, Hartman DM, Paridon SM, Wernovsky G, Spray TL, Gaynor JW. Late neurodevelopmental outcome after repair of total anomalous pulmonary venous connection. J Thorac Cardiovasc Surgery. 129(5):1091-1097, 2005.
200. Marino, BS, Wernovsky, G, Pasquali, SK, Bockoven, JR, McBride, M, Cho, CJ, Spray,TL, Paridon, SM. Exercise performance in children and adolescents after the Ross procedure. Cardiol Young, 2006;16:40-47.
201. Tabbutt S, Ittenbach RF, Nicolson SC, Burnham N, Hittle S, Spray TL, Gaynor JW. Intracardiac temperature monitoring in infants following heart surgery. J Thorac Cardiovasc Surg 2006;131:614-620.
202. Mitchell, ME, Ittenbach RF, Gaynor JW, Wernovsky G, Nicolson SC and Spray TL. Intermediate outcomes after the Fontan procedure in the current era. J. Thorac Cardiovasc Surg 2006; 131(1):172-180.
203. Gaynor JW, Jarvik GP, Bernbaum J, Gerdes M, Wernovsky G, Burnham NB, D’Agostino JA, Zackai E, McDonald-McGinn DM, Nicolson SC, Spray TL and Clancy RR. The relationship of postoperative electrographic seizures to neurodevelopmental outcome at 1 year of age after neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg 2006; 131(1):181-189.
204. Seliem, M.A., Fedec, A., Cohen, MS, Ewing, S, Farrell, PE Jr., Rychik, J, Schultz, AH, Gaynor, J.W., Spray, TL. Real time 3-dimensional echocardiographic imaging of congenital heart disease using matrix- array technology: Freehand real-time scanning adds instant morphologic details not well delineated by conventional 2-dimensional imaging. J Am Soc Echocardiogr 2006;19(2):121-129.
205. Kaltman JR, Jarvik GP, Bernbaum J, Wernovsky G, Gerdes M, Zackai E, Clancy RR, Nicholson SC, Spray TL, and Gaynor, J.W. Neurodevelopmental outcome after early repair of a ventricular septal defect with or without aortic arch obstruction. J Thorac Cardiovasc Surg 2006; 131:792-798.
206. Wernovsky G, Rome J, Tabbutt, S, Rychik, J, Cohen, MS, Paridon, SM, Webb, G, Dodds, L. Gallagher, MA, Fleck, DA, Spray, TL, Vetter, VL, Gleason, MM. Guidelines for the outpatient management of complex congenital heart disease. Congenit Heart Dis 2006,1:10-26.
207. Tabbutt S, Ittenbach RF, Nicolson SC, Burnham N, Hittle S, Spray TL, Gaynor JW. Intracardiac temperature monitoring in infants after cardiac surgery. J Thorac Cardiovasc Surg 2006; 131(3): 614-620.
208. Zuppa AF, Nicolson SC, Adamson PC, Wernovsky G, Mondick JT, Burnham N, Hoffman TM, Gaynor JW, Davis LA, Greeley WJ, Spray TL and Barrett JS. Population pharmacokinetics of milrinone in neonates with hypoplastic left heart syndrome undergoing stage 1 reconstruction. Anesth Analg 2006; 102(4):1062-1069.
209. Ravishankar C, Dominguez T, Kreutzer J, Wernovsky G, Marino BS, Godinez R, Priestly MA, Gruber PJ, Gaynor JW, Nicolson SC, Spray TL and Tabbutt S. Extracorporeal membrane oxygenation after stage 1 reconstruction for hypoplastic left heart syndrome. Ped Crit Care Med 2006; 7:319-323: May.
210. Kim, RW and Spray, TL. Surgical Correction of Aortico-Left Ventricular Tunnel. Sem Thorac Cardiovasc Surg Pediatr Card Surg Annu; 2006;177-178.
211. Jacobs JP, Jacobs ML, Franklin RCG, Colan SD, Tchervenkov CI, Maraszewski B, Gaynor JW, Spray TL, Stellin G, Aiello VD, Beland MJ, Krogmann ON, Kurosawa H, Weinberg PM, Elliot MJ, Mavroudis C and Anderson R. Classification of the functionally univentricular heart: Unity from mapped codes: Cardiol Young 2006; 16(suppl): 9-21.
212. Konstantinov, IE, Karamlou, T, Williams, WG, Quaegebeur, JM, del Nido, PJ, Spray, TL, Caldarone, CA, Blackstone, EH, McCrindle, BW. Congenital Heart Surgeons Society. Surgical management of aortopulmonary window associated with interrupted aortic arch: A Congenital Heart Surgeons Society study. J Thorac Cardiovasc Surg 2006; 131(5): 1136-1141.
213. Gillespie M, Kuijpers M, Rossem MV, Tabbutt S, Ravishankar, C, Gaynor JW, Spray TL and Clark B. Determinants of intensive care unit length stay for infants undergoing cardiac surgery. Congenital Heart Dis 1:152-160, 2006.
214. Gruber PJ, Fuller S, Cleaver KM, Abdullah I, Gruber SB, Nicolson SC, Gaynor JW, Wernovsky G, Abdullah, I, Gruber, SB, and Spray TL. Early results of single-stage biventricular repair of severe aortic hypoplasia or atresia with ventricular septal defect and normal left ventricle. J Thorac Cardiovasc Surg 132;2:260-263.
215. Marino, BS, Wernovsky, G, McElhinney, DB, Jawad, A, Kreb, DL, Mantel, SF, van der Woerd, WL, Gaynor, JW, Cohen, MS, and Spray, TL. Neo-aortic valvar function after the arterial switch. Cardiol in the Young 2006;16:481-489.
216. Meyer D, Zamora G, Wernovsky G, Ittenbach RF, Gallagher PR, Tabbutt S, Gruber PJ, Nicolson SC, Gaynor JW and Spray TL. Outcomes of the Fontan procedure utilizing cardiopulmonary bypass with aortic crossclamping. Ann Thorac Surg 2006; 82:1611-1620.
217. Marino, BS, Pasquali, S, Spray, TL and Wernovsky, G: Is the Ross procedure as good as we thought it would be? Cardiol Young; 2006; (Suppl. 3):125-130.
218. McBride MG, Kirshbom PM, Gaynor JW, Ittenbach RF, Wernovsky G, Clancy RR, Flynn TB,Hartman DM, Spray TL, Tanel RE, Santiago MC and Paridon SM. Late cardiopulmonary and musculoskeletal exercise performance following repair for total anomalous pulmonary venous connection during infancy. J Thorac Cardiovasc Surg 2007;133(6):1533-9.
219. Tanel RE, Kirshbom PM, Paridon SM, Hartman DM, Burnham NB, McBride M, Ittenbach RI, Spray TL, and Gaynor JW. Long-term noninvasive arrhythmia assessment after total anomalous pulmonary venous connection repair. Am Heart J 2007 Feb;153(2):267-74.
220. Glatz JA, Tabbutt S, Gaynor JW, Rome JJ, Montenegro L, Spray TL and Rychik J. Hypoplastic left heart syndrome with atrial level restriction in the era of prenatal diagnosis. Ann Thorac Surg 2007; 84: 1633-38.
221. Brothers JA, McBride MG, Seliem MA, Marino BS, Tomlinson RS, Pampaloni MH, Gaynor JW, Spray TL and Paridon SM. Evaluation of myocardial ischemia after surgical repair of anomalous aortic origin of a coronary artery in a series of pediatric patients. J Am Coll Cardiol 2007; 50: 2078-82.
222. Wernovsky G, Kuijpers M, Van Rossem MC, Ravishankar C, Dominguez T, Godinez T, Dodds KM, Ittenbach RF, Bird GL, Gaynor JW, Spray TL, and Tabbutt S. Postoperative course in the cardiac intensive care unit following the first stage of Norwood reconstruction. Cardiol Young 2007 Dec;17(6),652-665.
223. Shillingford AJ, Ittenbach RF, Marino BS, Rychik J, Clancy RR, Spray TL, Gaynor JW, Wernovsky G. Aortic morphometry and microcephaly in hypoplastic left heart syndrome. Cardiology in the Young 2007; 17: 189-95.
224. Ballweg JA, Wernovsky G, Ittenbach RF, Bernbaum J, Gerdes M, Gallagher PR, Dominquez TE, Zackai TE, Clancy RR, Nicolson S, Spray TL, Gaynor JW. Hyperglycemia after infant cardiac surgery does not adversely impact neurodevelopmental outcome. Ann Thorac Surg 2007; 84: 2052-8.
225. Ballweg JA, Dominguez TE, Ravishankar C, Kreutzer J, Marino BS, Bird GL, Gruber PJ, Wernovsky G, Gaynor JW, Nicolson SC, Spray TL and Tabbutt S. A contemporary comparison of the effect of shunt type in hypoplastic left heart syndrome on the hemodynamics and outcome at stage 2 reconstruction. J Thorac Cardiovasc Surgery 2007; 134: 297-303.
226. Marino, BS, Pasquali, SK, Wernovsky, G, Pudusseri, A, Rychik, J, Montenegro, L, Shera, D, Spray, TL, Cohen, MS. Accuracy of intraoperative transesophageal echocardiography in the prediction of future neo-aortic valve function after the Ross procedure in children and young adults. Congenit Heart Dis 2008 Jan; 3(1):39-46.
227. Sivarajan VB, Chrisant MR, Ittenbach RF, Clark BJ, Hanna BD, Paridon SM, Spray TL, Wernovsky G, and Gaynor, JW. Prevalence and risk factors for tricuspid valve regurgitation after pediatric heart transplantation. J Heart and Lung Transplantation 2008; 27: 494-500.
228. Pasquali, SK, Cohen, MS, Shera, D, Wernovsky, G., Spray, TL, Marino, BS: The relationship between neo-aortic root dilation, insufficiency, and reintervention following the Ross procedure in infants, children, and young adults. J Am Coll Cardiol 2007 May 1;49(17):1806-12. Epub 2007 Apr 16.
229. Khan AR, Birbach M, Cohen MS, Ittenbach RF, Spray TL, Levy RJ, and Gaynor JW. Chronic hypoxemia increases ventricular brain natriuretic peptide precursors in neonatal swine. Ann Thorac Surg 2008; 85: 618-23.
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