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David D. Aufhauser, Jr., M.D.
General Surgery Resident

 
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Office:
Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

David.Aufhauser@uphs.upenn.edu

 

Dr. Aufhauser is a sixth year surgery resident planning on a career in transplant surgery. He grew up in Washington, DC and graduated from Stanford University with degrees in Biological Sciences and History in 2007. He received his MD from University of Pennsylvania School of Medicine in 2011. He is currently a research fellow in the lab of Dr. Matthew Levine at the Children’s Hospital of Philadelphia. His research focuses on interventions to mitigate iscehmia-reperfusion injury in kidney and liver transplantation.

 
Appointments
2014 - present Postdoctoral Researcher
 
2011 - present Assistant Instructor in Surgery
 
 
 
 
 
 
 
 
 
Education/Training
2007 - 2011 MD - University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2003 - 2007 BS - Biological Sciences / BA - History
Stanford University
Stanford, California
 
 
 
 
 
 
Memberships/Societies
  • Alpha Omega Alpha
  • Phi Beta Kappa
  • American Society of Transplant Surgeons
  • American College of Surgeons
  • ssociation of Academic Surgeons
 
 
 
 
Research
07/2014 - present
University of Pennsylvania, Department of Surgery, Transplantation Division, Philadelphia, Pennsylvania
Post-doctoral Research Fellow, Dr. Matthew Levine
Developing novel interventions for mitigation of ischemia-reperfusion injury in renal and liver transplantation
 
06/2010 – 09/2010
University of Pennsylvania, Department of Surgery, Transplantation Division, Philadelphia, Pennsylvania
Researcher, Dr. Peter Abt
Investigated the role of donor steatosis on liver transplant outcomes; examined ways to predict, prevent, and manage intraoperative cardiac arrests during liver transplantations
 
01/2006 – 06/2007
Stanford University, Department of Pediatrics, Stanford, California
Undergraduate Researcher, Drs. Alan Krensky and Carol Clayberger
Investigated the function of the human immune molecule granulysin through transgenic mice
 
06/2004 – 09/2004
Vaccine Research Center, NIH, Bethesda, Maryland
Undergraduate Researcher, Dr. Gary Nabel
Developed an independent project using pseudo-viruses to investigate the mechanisms of antibody neutralization and of viral assembly
 

06/2002 – 08/2002
National Cancer Institute, NIH, Bethesda, Maryland
Cancer Research Training Award Recipient, Dr. Maryalice Stetler-Stevenson
Studied the role of the TIMP-1 enzyme in lymphoma through transgenic mouse models

 
Publications
  1. Aufhauser DD Jr, Wang Z, Murken DR, Bhatti TR, Wang Y, Ge G, Redfield RR, Abt PL, Wang L, Svoronos N, Thomasson A, Reese PP, Hancock WW, Levne MH.  Improved Renal Ischemia Tolerance in Females Influences Kidney Transplantation Outcomes.  Journal of Clinical Investigation.  2016 April 18.
  2. George J, Aufhauser DD Jr, Raper SE.  Bouvert’s Syndrome Resulting in Gallstone Ileus.  Journal of Gastrointestinal Surgery.  2015 Feb 24.
  3. Levine MH, Wang Z, Bhatti TR, Wang Y, Aufhauser DD Jr, McNeal S, Liu Y, Cheraghlou S, Han R, Wang L, Hancock WW.  Class-Specific Histone/Protein Deacetylase Inhibition Protects Against Renal Ischemia Reperfusion Injury and Fibrosis Formation.  American Journal of Transplantation.  2015 Feb 23.
  4. Aufhauser DD Jr, Rose T, Levine M, Barnett R, Ochroch EA, Aukburg
    S, Greenblatt E, Olthoff K, Shaked A, Abt P.  Cardiac arrest associated with reperfusion of the liver during transplantation: incidence and proposal for a management algorithm.  Clinical Transplantation. 2013 Mar-Apr; 27(2): 185-92.
  5. Massey PR, Sakran JV, Mills AM, Sarani B, Aufhauser DD Jr, Sims CA, Pascual JL, Kelz RR, Holena DN.  Hyperbaric oxygen therapy in necrotizing soft tissue infections.  Journal of Surgical Research. 2012 Mar 28; 117(1): 146-51.
Oral Presentations
  1. Aufhauser DD Jr, Murken D, Wang Z, Ge G, Bhatti TR, Hancock WW, Levine MH.   Gender Differences in Murine Renal Ischemia-Reperfusion Injury are Mutable with Hormonal Manipulation.  Academic Surgical Congress, Jacksonville, FL.  Feb 2016.
  2. Murken D, Aufhauser DD Jr, Wang Z, Ge G, Bhatti TR, Hancock WW, Levine MH.  Histone Deacetylase-2 Gene Deletion In Mice Extends Tolerance of Renal Ischemia/Reperfusion Injury.  Academic Surgical Congress, Jacksonville, FL.  Feb 2016.
  3. Levine MH, Thomasson A, Aufhauser DD Jr, Redfield R, Abt PL, Reese P.  Gender Differences in Kidney Transplant Delayed Graft Function Are Independent of Donor-Recipient Size Mismatch.  American Transplant Congress, Philadelphia, PA.  May 2015.
  4. Aufhauser DD Jr, Eddinger K, Olthoff KE, Shaked A, Hoteit MA, Furth EE, Abt PL, Levine MH.  Unrecognized Synchronous Hepatocellular Carcinoma Lesions in Explanted Liver Transplant Specimens.   Controversies in Transplantation, Breckinridge, CO.  Mar 2015.
  5. Aufhauser DD Jr, Wang Z, Cheraghlout S, Want Y, Bhatti TR, Hancock WW, Levine MH.  HDAC2 Gene Deletion Protects from Renal Ischemia-Reperfusion Injury and Is Intrinsic to Renal Tissue.  American Society of Transplant Surgeons, Winter Symposium, Miami, FL.  Jan 2015.
Poster Presentations
  1. Aufhauser DD JR, Sadot E, Murken D, Eddinger K, Goldberg DS, Furth EE, Abt PL, DeMatteo RP, Levine MH.  Occult Multifocal Hepatocellular Carcinoma in Surgical Patients.  American Transplant Congress, Boston MA, June 2016.
  2. Aufhauser DD Jr, Murken D, Wang Z,  Samanta A, , Ge G, Bhatti TR, Hancock WW, Levine MH.  Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-repressor Complex Expression.  American Transplant Congress, Boston MA, June 2016.
  3. Pourfathi M, Aufhauser DD Jr,  Murken D, Wang Z, Kadlecek S, Gatens H, Naji A, Levine MH, Rizi R.  In vivo Assessment of Metabolic Derangements in Renal Ischemia-Reperfusion Injury Using Carbon-13 HP-MRI.  International Society of Magnetic Resonance Medicine, Singapore, Singapore, May 2016.
  4. Aufhauser DD Jr, Murken D, Wang Z,  Samanta A, , Ge G, Bhatti TR, Hancock WW, Levine MH.  Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-repressor Complex Expression.  Metropolitan Philadelphia Chapter of the American College of Surgeons, Annual Meeting, Philadelphia PA.  May 2016.
  5. Aufhauser DD Jr, Murken D, Wang Z, Ge G, Bhatti TR, Hancock WW, Levine MH.   HDAC11 Deletion Increases Tolerance of Warm Renal Ischemia-Reperfusion Injury.  American Society of Transplant Surgeons, Winter Symposium, Miami FL.  Jan 2016.
  6. Aufhauser DD Jr, Murken D, Wang Z, Ge G, Bhatti TR, Hancock WW, Levine MH.   HDAC2 Deletion Mitigates Renal Injury After Prolonged Cold Ischemia Prior to Transplant.  American Society of Transplant Surgeons, Winter Symposium, Miami FL.  Jan 2016.
  7. Murken D, Peng AW, Aufhauser DD Jr, Goldberg DS, Levine MH.  Same Policy, Different Impact: Center and Regional Effects of SHARE 35 Liver Allocation.  American Society of Transplant Surgeons, Winter Symposium, Miami FL.  Jan 2016.
  8. Aufhauser DD Jr, Wang Z, Ge G, Bhatti TR, Hancock WW, Levine MH.   Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Ischemia-Reperfusion Injury Are Intrinsic to the Kidney.  American Society of Nephrology, Kidney Week, San Diego, CA.  November 2016.
  9. Aufhauser DD Jr, Wang Z, Cheraghlout S, Bhatti TR, Hancock WW, Levine MH.  Profound Effect of HDAC2 Gene Deletion on Renal Ischemia-Reperfusion Injury Is Intrinsic to the Kidney and Includes Protection Against Cold Ischemia.  American Transplant Congress, Philadelphia, PA.  May 2015.
  10. Aufhauser DD Jr, Eddinger K, Furth EE, Abt PL, Levine MH.  Unrecognized Synchronous Hepatocellular Carcinoma Lesions in Explanted Liver Transplant Specimens.   American Transplant Congress, Philadelphia, PA.  May 2015.
  11. Aufhauser DD Jr, Wang Z, Cheraghlout S, Want Y, Bhatti TR, Hancock WW, Levine MH.  Profound Effect of HDAC2 Gene Deletion on Renal Ischemia-Reperfusion Injury Is Intrinsic to the Kidney and Includes Protection Against Cold Ischemia.  Philadelphia Academy of Surgery, Resident Research Competition, Philadelphia, PA.  Feb 2015.
Book Chapters
  1. Aufhauser DD Jr, Levine MH.  Immunology and Transplantation.  The Surgical Review.  Lippincott Williams & Wilkins, 4th ed. Sept 2015.
 
Awards
2016 Jonathon E. Rhoades Resident Research Award
 
2016 1st Place Basic Science Poster
Metropolitan Philadelphia Chapter of American College of Surgeons Annual Meeting
 
2016 Poster of Distinction, Winter Meeting of the American Society of Transplant Surgeons
 
2011 I.S. Ravdin Award for Excellence in Surgery
 
2011 Merck Manual Prize
 
2010 Alpha Omega Alpha
 
2007 - 2011 Gamble Scholar
 
2007 Firestone Medal for Excellence in Undergraduate Research, Stanford University
 
2006 Phi Beta Kappa

Dr. David Aufhauser

 
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