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Matthew M. Boelig, M.D.
General Surgery Resident

 
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Office:
Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

Matthew.Boelig@uphs.upenn.edu

 

Dr. Boelig is a sixth year surgery resident planning on a career in academic pediatric surgery. He grew up in New Hampshire and graduated from Yale University with a degree in Biology in 2006. He received his MD from the Johns Hopkins University School of Medicine in 2010. He was a research fellow in the labs of Dr. Alan Flake and Dr. William Peranteau at The Center for Fetal Research at The Children’s Hospital of Philadelphia. His research focuses on using a murine model to improve the efficacy and technique of in utero stem cell therapy, as well identifying the role of circulating endothelial progenitor cells in congenital diaphragmatic hernia. He is also conducting a clinical study that assesses long-term outcomes in patients who required fetal intervention for congenital cystic adenomatoid malformation (CCAM).

 
Appointments
2013 - 2015 Postdoctoral Researcher
 
2010 - present Assistant Instructor in Surgery
 
 
 
 
 
 
 
 
Education/Training
2006 - 2010 MD – Johns Hopkins University School of Medicine
Baltimore, Maryland
 
2002 - 2006 BS – Yale University (Biology)
New Haven, Connecticut
 
 
 
 
 
 
 
Memberships/Societies
  • American College of Surgeons – Resident Member
 
 
 
 
 
 
 
 
 
Research

7/2013 – 6/2015
Children’s Hospital of Philadelphia
Research fellow, PIs: Dr. Alan Flake and Dr. William Peranteau

 
06/2009 – 05/2010
Johns Hopkins Department of Surgery, Baltimore, Maryland
Researcher, Dr. Elliot Haut
Conducted a patient safety study pertaining to the use of sequential compressive devices (SCDs) at the Johns Hopkins Hospital.
 
10/2005 – 04/2006
Yale University, Department of Pathology
New Haven, Connecticut

Undergraduate Researcher, Dr. Michael Robek
Senior undergraduate research project entitled, “The Involvement of Immunoproteasome Subunits in the Non-Cytopathic Inhibition of Hepatitis B Virus.” The project focused on determining the role of PA28-beta, an interferon-gamma induced component of the proteasome catalytic complex, in the clearance of the virus from infected murine hepatocytes.
 
06/2005 – 07/2005
National Blood Service, Oxford, United Kingdom
Undergraduate Researcher, Dr. David Roberts
Awarded a Howard Hughes summer scholarship to work with Dr. David Roberts, head of the research group at the Blood Research Laboratory of the National Blood Service in Oxford, UK. Sequenced two specific loci thought to be involved in providing immunoprotection against P. falciparum infection using DNA samples from malaria victims in Africa.
 
Publications
Original Articles
  1. Boelig MM, Laje P, Peranteau WH. Child with abdominal pain and a cystic pelvic mass.  Clinical Challenge. JAMA Surgery. Published online May 20, 2015.
  2. Peranteau WH, Adzick NS, Boelig MM, Flake AW, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a single-institution review and predictors of survival in 75 cases. Journal of Pediatric Surgery. 2015 Feb; 50 (2): 301-5.
  3. Boelig MM, Streiff MB, Hobson DB, Kraus PS, Pronovost PJ, Haut ER. Are sequential compression devices commonly associated with in-hospital falls? A myth-busters review using the patient safety net database. Journal of Patient Safety. 2011 June; 7 (2): 77-9.
Book Chapters
  1. Boelig MM and Flake AW. “In Utero Stem Cell Transplantation.” Prenatal Stem Cells and Regenerative Medicine. Ed. Dario Fauza and Mahmud Bani. Accepted – in press.
Oral Presentations
  1. Boelig MM, Tsai J, Kim AG, Conner MA, Loukogeorgakis SP, Li P, Zon LI, Flake AW, Peranteau WH. The Use of Eicosanoids to Enhance Donor Cell Engraftment after In Utero Hematopoietic Cell Transplantation (IUHCT). 57th American Society of Hematology (ASH) Annual Meeting and Exposition. Orlando, FL, USA. (Accepted for December 5, 2015).
  2. Boelig MM, Kim AG, Conner MA, Loukogeorgakis SP, Flake AW, Peranteau WH. LL-37 Enhances Homing and Long-Term Engraftment after in Utero Hematopoietic Cell Transplantation (IUHCT).  American College of Surgeons (ACS) Clinical Congress.  Targeted and Cell-Based Therapies session. San Francisco, CA, USA (October 27, 2014).
  3. Boelig MM, Collins JL, Mehta S, Parks EP, Williams NN, Aggarwal R. Bariatric Surgery for Adolescent Obesity: A Systematic Review of 1,322 Patients. International Federation for the Surgery of Obesity and Metabolic Disorders (IFSO) XIX World Congress. Montreal, Quebec, Canada. August 29, 2014.
  4. Boelig MM, Collins JL, Mehta S, Parks EP, Williams NN, Aggarwal R. Bariatric Surgery for Adolescent Obesity: A Systematic Review of 1,322 Patients. Obesity Week. American Society for Metabolic and Bariatric Surgery. November 12, 2013. Atlanta, GA.
  5. Boelig MM and McFarland EG. Humerus Pain – Collegiate Baseball Infielder. American College of Sports Medicine’s 55thAnnual Meeting. Indianapolis, IN. 5/31/08.
Posters
  1. Boelig MM, Kim AG, Li H, Flake AW, Peranteau WH The Intravenous Route Optimizes Engraftment and Survival in the Murine Model of In Utero Hematopoietic Cell Transplantation (IUHCT). 57th American Society of Hematology (ASH) Annual Meeting and Exposition. Orlando, FL, USA. (Accepted for December 5, 2015).
  2. Boelig MM, Kim AG, Conner MA, Loukogeorgakis SP, Flake AW, Peranteau WH. LL-37 Enhances Homing and Long-Term Engraftment after in Utero Hematopoietic Cell Transplantation (IUHCT).  American Pediatric Surgical Association (APSA) 46th Annual Meeting. Fort Lauderdale, Florida, USA (April 30 – May 5, 2015).
  3. Boelig MM, Collins JL, Mehta S, Parks EP, Williams NN, Aggarwal R. Bariatric Surgery for Adolescent Obesity: A Systematic Review of 1,322 Patients. Obesity Week. American Society for Metabolic and Bariatric Surgery. November 13-15, 2013. Atlanta, GA.
Other Abstracts
  1. Vrecenak JD, Pearson EG, Boelig MM, Olive A, Li H, Johnson MP, Flake AW. Maternal Allo-Antibody Response Limits Engraftment Following Fully Mismatched In Utero Hematopoietic Cell Transplantation in a Preclinical Canine Model. American Pediatric Surgical Association (APSA) 46th Annual Meeting. Fort Lauderdale, Florida, USA (April 30 – May 5, 2015).
  2. Kim AG, Vrecenak JD, Conner MA, Boelig MM, Loukogeorgakis SP, Flake AW, Peranteau WH. A Novel Hematopoietic Stem Cell (HSC) Mobilizing Agent Enhances Long-term Allogeneic Engraftment After In Utero Hematopoietic Stem Cell Transplantation (IUHCT). American College of Surgeons (ACS) Clinical Congress. San Francisco, CA, USA (October 26-30, 2014).
  3. Peranteau WH, Adzick NS, Boelig MM, Flake AW, Hedrick HL, Howell LJ, Moldenhauer JS, Khalek N, Martinez-Poyer J, Johnson MP. Thoracoamniotic shunts for the management of fetal lung lesions and pleural effusions: a  single-institution review and predictors of survival in 75 cases. British Association of Paediatric Surgeons 61st Congress. Edinburgh, Scotland, United Kingdom (2014, July).
  4. Boelig MM, Conner M, Kim A, Vrecenak J, Tsai J, Flake AW, Peranteau WH. Ex vivo modification of donor hematopoietic cells to enhance allogeneic engraftment following in utero hematopoietic cell transplantation (IUHCT). Conference of Fetal Therapies and Maternal-Fetal Tolerance. UCSF, San Francisco, CA (2014, April).
  5. Carson J, Boelig MM, Carrino JA, McFarland EG. Sternoclavicular Stress Lesions in an Adolescent Gymnast. Medicine & Science in Sports & Exercise. Vol 40. No. 5 Supplement. 2008.
Accepted
  1. Peranteau WH, Boelig MM, Khalek N, Moldenhauer JS, Martinez-Poyer J, Hedrick HL, Flake AW, Johnson MP, Adzick NS. Effect of single and multiple courses of maternal betamethasone on prenatal congenital lung lesion growth and fetal survival. Journal of Pediatric Surgery. Date TBD. 
 
Awards
 
 
 
 
 
 
 
 
 

Dr. Matthew Boelig

 
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