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Javier A. Couto, MD
Plastic Surgery Resident

 
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Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
Philadelphia, PA 19104
Telephone: 215-662-6156
Fax: 215-662-7983

Contact Information (internal use only)

Javier.Couto@uphs.upenn.edu

 

Javier A. Couto, MD is a first-year resident in the Integrated Plastic Surgery Residency Program. He is interested in clinical and translational research within the field of plastic and reconstructive surgery. He plans to pursue a career in academic plastic surgery.

 
Appointments
2017 - present Assistant Instructor in Surgery
 
 
 
 
 
 
 
 
 
Education/Training
2010 - 2017 MD - University of Puerto Rico
 
2013 - 2016 Research Fellow - Boston Children’s Hospital, Harvard Medical School
 
2005 - 2009 BS - University of Puerto Rico (Biology)
 
 

 

 
 
Memberships/Societies
  • Plastic Surgery Research Council
  • American Society of Plastic Surgeons
  • American College of Surgeons
  • American Medical Association
 
 
 
 
 
 
 
Research
Oral Presentations
  1. Couto J.A., Ayturk U.M., Hann S., Mulliken J.B., Williams K.L., Huang A.Y., Fishman S.J., Boyd T.K., Kozakewich H.P.W., Bischoff J., Greene A.K., Warman M.L. (October, 2016). Somatic Activating Mutations in GNAQ and GNA11 are Associated with Congenital Hemangioma. Northeastern Society of Plastic Surgeons 33rd Annual Meeting; Baltimore, MD, USA.
  2. Couto J.A., Vivero M.P., Kozakewich H.P., Taghinia A.H., Mulliken J.B., Warman M.L., Greene A.K. (April, 2016). A Somatic MAP3K3 Mutation is Associated with Verrucous Venous Malformation. International Society for the Study of Vascular Anomalies 21st International Workshop; Buenos Aires, ARG.
  3. Couto J.A., Vivero M.P., Upton J., Padwa B.L., Warman M.L., Mulliken J.B., Greene A.K. (April, 2016). Facial Infiltrating Lipomatosis Contains Somatic PIK3CA Mutations in Multiple Tissues International Society for the Study of Vascular Anomalies 21st International Workshop; Buenos Aires, ARG. 
  4. Couto J.A., Vivero M.P., Upton J., Padwa B.L., Warman M.L., Mulliken J.B., Greene A.K. (October, 2015). Facial Infiltrating Lipomatosis Contains Somatic PIK3CA Mutations in Multiple Tissues. American Society of Plastic Surgeons: The Meeting; Boston, MA, USA.
  5. Couto J.A., Maclellan R.A., Greene A.K. (September, 2015). Management of Vascular Anomalies and Related Conditions Using Suction-Assisted Tissue Removal. Northeastern Society of PlasticSurgeons 32nd Annual Meeting; Philadelphia, PA, USA. 
  6. Couto J.A., Vivero M.P., Kozakewich H.P., Taghinia A.H., Mulliken J.B., Warman M.L., Greene A.K. (June, 2015). A Somatic MAP3K3 Mutation is Associated with Verrucous Venous Malformation. New England Society of Plastic and Reconstructive Surgeons 56th Annual Meeting; Westbrook, CT, USA.
  7. Couto J.A., Huang L., Vivero M.P., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., GreeneA.K. (June, 2015). Endothelial Cells from Capillary Malformations are Enriched for Somatic GNAQ Mutations and Aberrantly Express PDGFRB. New England Society of Plastic and ReconstructiveSurgeons 56th Annual Meeting; Westbrook, CT, USA. 
  8. Couto J.A., Kozakewick H.P., Greene A.K. (June, 2015). Pediatric Acral Arteriovenous Lesion: Clinical Presentation and Histopathology. New England Society of Plastic andReconstructive Surgeons 56th Annual Meeting; Westbrook, CT, USA.
  9. Couto J.A., Vivero M.P., Upton J., Padwa B.L., Warman M.L., Mulliken J.B., Greene A.K. (June, 2015). Facial Infiltrating Lipomatosis Contains Somatic PIK3CA Mutations in Multiple Tissues Oral Presentation presented at:New England Society of Plastic and Reconstructive Surgeons 56th Annual Meeting; Westbrook, CT, USA. 
  10. Couto J.A., Huang L., Vivero M.P., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., GreeneA.K. (May, 2015). Endothelial Cells from Capillary Malformations are Enriched for Somatic GNAQ Mutations and Aberrantly Express PDGFRB. Plastic Surgery Research Council 60th AnnualMeeting; Seattle, WA, USA.
  11. Couto J.A., Vivero M.P., Kozakewich H.P., Taghinia A.H., Mulliken J.B., Warman M.L., Greene A.K. (May, 2015). A Somatic MAP3K3 Mutation is Associated with Verrucous Venous Malformation. Plastic Surgery Research Council 60th Annual Meeting; Seattle, WA, USA.
  12. Couto J.A., Huang L., Vivero M.P., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., GreeneA.K. (April, 2015). Endothelial Cells from Capillary Malformations are Enriched for Somatic GNAQ Mutations and Aberrantly Express PDGFRB. American Association of Plastic Surgeons 94thAnnual Meeting; Scottsdale, AZ, USA.
  13. Couto J.A., Sullivan J.E., Greene A.K. (September, 2014). Facial Wound Closure in 261 Children Using a 7-0 Absorbable Suture Dressing. Northeastern Society of Plastic Surgeons 31st AnnualMeeting; Providence, RI, USA.
  14. Couto J.A., Greene A.K. (June, 2014). Management of Problematic Infantile Hemangioma Using Intralesional Triamcinolone: Efficacy and Safety in 100 Infants. New England Society of Plasticand Reconstructive Surgeons 55th Annual Meeting; Sebasco Estates, ME, USA.
  15. Couto J.A., Vivero M.P., Huang L., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., Greene A.K. (April, 2014). Allelic and Possible Locus Heterogeneous Causes for Capillary Malformation. International Society for the Study of Vascular Anomalies 20th International Workshop; Melbourne, AUS.
  16. Couto J.A., Greene A.K. (March, 2014). Management of Problematic Infantile Hemangioma Using Intralesional Triamcinolone: Efficacy and Safety in 100 Infants. Plastic Surgery Research Council59th Annual Meeting; New York City, NY, USA. 
  17. Couto R.A., Couto J.A., Maclellan R.A., Bischoff J., Vivero M.P., Purcell P., Fishman S.J., Mullken J.B., Greene A.K. (March, 2013). Capillary Malformation: Expression of Angiogenic and Vasculogenic Factors at: 33rd Annual Forum of Research and Education, UPR Medical Sciences Campus; San Juan, PR, USA.
Poster Presentations
  1. Couto J.A., Konczyk D.J., Vivero M.P., Kozakewich H.P., Upton J., Fu X., Padwa B.L., Mulliken J.B., Warman M.L., Greene A.K. (May, 2016). Somatic PIK3CA Mutations are Present in Multiple Tissues of Facial Infiltrating Lipomatosis Poster presented at: Dr. M. Judah Folkman Research Day, Boston Children's Hospital; Boston, MA, USA.
  2. Couto J.A., Konczyk D.J., Kozakewich H.P., Greene A.K. (April, 2016). Pediatric Acral Arteriovenous Lesion: Clinical Presentation and Histopathology Poster presented at: International Society for the Study of VascularAnomalies 21st International Workshop; Buenos Aires, ARG.
  3. Couto J.A., Vivero M.P., Upton J., Padwa B.L., Warman M.L., Mulliken J.B., Greene A.K. (April, 2016). Facial Infiltrating Lipomatosis Contains Somatic PIK3CA Mutations in Multiple Tissues Poster presented at: New EnglandScience Symposium, Harvard Medical School; Boston, MA, USA. 
  4. Couto J.A., Huang L., Vivero M.P., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., Greene A.K. (May, 2015). Endothelial Cells from Capillary Malformations are Enriched for Somatic GNAQ Mutations and Aberrantly Express PDGFRB Poster presented at: Dr. M. Judah Folkman Research Day, Boston Children’s Hospital; Boston, MA, USA.
  5. Couto J.A., Vivero M.P., Kozakewich H.P., Taghinia A.H., Mulliken J.B., Warman M.L., Greene A.K. (May,2015). A Somatic MAP3K3 Mutation is Associated with Verrucous Venous Malformation Poster presented at: Dr. M. Judah Folkman Research Day, Boston Children’s Hospital; Boston, MA, USA.
  6. Couto J.A., Vivero M.P., Huang L., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., GreeneA.K. (May, 2014). Allelic and Possible Locus Heterogeneous Causes for Capillary Malformations Poster presented at: 3rd Annual Harvard Surgery Research Day Symposium; Boston, MA, USA.
  7. Couto J.A., Vivero M.P., Huang L., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., Greene A.K. (May, 2014). Allelic and Possible Locus Heterogeneous Causes for Capillary Malformations Poster presentedat: Dr. M. Judah Folkman Research Day, Boston Children's Hospital; Boston, MA, USA.
  8. Couto J.A., Couto R.A., Maclellan R.A., Bischoff J., Vivero M.P., Purcell P., Fishman S.J., Mullken J.B., Greene A.K. (April, 2014). Capillary Malformation: Expression of Angiogenic and Vasculogenic Factors Poster presentedat: International Society for the Study of Vascular Anomalies 20th International Workshop; Melbourne, AUS.
  9. Couto J.A., Greene A.K. (April, 2014). Management of Problematic Infantile Hemangioma Using Intralesional Triamcinolone: Efficacy and Safety in 100 Infants Poster presented at: International Society for the Study ofVascular Anomalies 20th International Workshop; Melbourne, AUS. 
  10. Maclellan R.A., Couto J.A., Greene A.K. (April, 2014). Operative Management of Vascular Anomalies and Related Conditions Using Liposuction. International Society for the Study of Vascular Anomalies 20th International Workshop; Melbourne, AUS.
  11. Couto J.A., Vivero M.P., Huang L., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., Greene A.K. (March, 2014). Allelic and Possible Locus Heterogeneous Causes for Capillary Malformations Poster presented at: Surgical Research Council’s 10th Annual Symposium in Cellular, Molecular, and Clinical Research in Surgery; Boston, MA, USA.
  12. Couto R.A., Couto J.A., Maclellan R.A., Bischoff J., Vivero M.P., Purcell P., Fishman S.J., Mullken J.B., Greene A.K. (December, 2012). Capillary Malformation: Expression of Angiogenic and Vasculogenic Factors Poster presented at: 3rd AEMPR Annual Research Symposium; Caguas, PR, USA.
 
Publications
Peer-Reviewed Articles
  1. Couto J.A., Konczyk D.J., Vivero M.P., Kozakewich H.P.W., Upton J., Fu X., Padwa B.L., Mulliken J.B., Warman M.L., Greene A.K. Somatic PIK3CA mutations are present in multiple tissues of facial infiltrating lipomatosis. Pediatr Res. 2017 Jun 30. [Epub ahead of print] PMID: 28665924.
  2. Couto J.A., Huang A.Y., Konczyk D.J., Goss J.A., Fishman S.J., Mulliken J.B., Warman M.L., Greene A.K. Somatic MAP2K1 mutations are associated with extracranial arteriovenous malformation. Am J Hum Genet. 2017 Mar 2;100(3):546-554. PMID: 28190454.
  3. Couto J.A., Uyturk U.M., Konczyk D.J., Goss J.A., Huang A.Y., Hann S., Reeve J.L., Liang M.G., Bischoff J., Warman M.L., Greene A.K. A somatic GNA11 mutation is associated with extremity capillary malformation and overgrowth. Angiogenesis. 2017 Jan 24. PMID: 28120216
  4. Huang L., Couto J.A., Pinto A., Alexandrescu S., Madsen J.R., Greene A.K., Sahin M., Bischoff J. Somatic GNAQ mutation is enriched in brain endothelial cells in Sturge-Weber syndrome. Pediatr Neurol. 2017 Feb;67:59-63. PMID: 27919468.
  5. Beijnen U.E.A., Maclellan R.A., Goss J.A., Couto J.A., Konczyk D.J., Greene A.K. Beckwith-Wiedemann syndrome and primary lymphedema of the lower extremity. Pediatr Dermatol. 2017 Jan;34(1):e51-e53. PMID: 27778389.
  6. Couto J.A.*, Ayturk U.M., Hann S., Mulliken J.B., Williams K.L., Huang A.Y., Fishman S.J., Boyd T.K., Kozakewich H.P., Bischoff J., Greene A.K., Warman M.L. Somatic activating mutations in GNAQ and GNA11 are associated with congenital hemangioma. Am J Hum Genet. 2016 Apr 7;98(4):789-795. PMID: 27058448 [* co-first author]
  7. Couto J.A., Huang L., Vivero M.P., Kamitaki N., Maclellan R.A., Mulliken J.B., Bischoff J., Warman M.L., Greene AK. Endothelial cells from capillary malformations are enriched for somatic GNAQ mutations. Plast Reconstr Surg. 2016 Jan;137(1):77e-82e. PMID: 26368330.
  8. Couto J.A., Maclellan R.A., Greene A.K. Management of vascular anomalies and related conditions using suction-assisted tissue removal. Plast Reconstr Surg. 2015 Oct;136(4):511e-514e. PMID: 26397270.
  9. Couto J.A., Schmidt B.A.R., Greene A.K. Nodular foot myxedema masquerading as lymphedema. Plast Reconstr Surg Glob Open. 2015 Aug 10;3(7):e457. PMID: 26301146
  10. Hassanein A.H., Couto J.A., Greene A.K. Circular excision and purse-string closure for pediatric facial skin lesions. J Craniofac Surg. 2015 Jul;26(5):1611-1612. PMID: 26107002.
  11. Hassanein A.H., Couto J.A., Mulliken J.B., Greene A.K. Stewart-Treves phenomenon: Lymphangiosarcoma arising in lymphedematous tissue is not a syndrome. Lymphat Res Biol. 2015 Sep;13(3):228-229. PMID: 25658055.
  12. D’Gama A.M., Geng Y., Couto J.A., LaCoursiere C.M., Hossain A., Hatem N., Barry B.J., Kwiatkowski D.J., Vinters H., Shendure J., Mathern G.W., Walsh C.A., Poduri A. Mammalian target of rapamycin pathway mutations cause hemimegalencephaly and focal cortical dysplasia. Ann Neurol. 2015 Apr;77(4):720-725. PMID: 25599672.
  13. Couto J.A., Vivero M.P., Kozakewich H.P., Taghinia A.H., Mulliken J.B., Warman M.L., Greene A.K. A somatic MAP3K3 mutation is associated with verrucous venous malformation. Am J Hum Genet. 2015 Mar;96(3):480-486. PMID: 25728774
  14. Couto J.A., Sullivan J.E., Greene A.K. Facial wound closure in children using a 7-0 absorbable suture dressing. J Craniofac Surg. 2015 Jan;26(1):76-78. PMID: 25534052.
  15. Couto J.A., Greene A.K. Management of problematic infantile hemangioma using intralesional triamcinolone: Efficacy and safety in 100 infants. J Plast Reconstr Aesthet Surg. 2014 Nov;67(11):1469-1474. PMID: 25104131.
  16. Couto J.A., Maclellan R.A., Greene AK. Infantile hemangioma: Treatment rate during the proliferating phase. J Craniofac Surg. 2014 Sep;25(5):1933-1934. PMID: 25119403.
Book Chapters
  1. Couto J.A., Fishman S.J., Greene A.K. Vascular Anomalies. In: Hansen AR (ed). Cloherty and Stark’s Manual of Neonatal Care. 8th ed. (Chapter 66, pp. 978-985). Wolters Kluwer; Philadelphia, PA. 2016.
  2. Couto J.A., Greene A.K. Vascular Anomalies. In: Lin SJ, Hijjawi JB (ed.). Plastic and Reconstructive Surgery Board Review: Pearls of Wisdom. 3rd ed. (Chapter 70, pp. 665-672). McGraw-Hill Education; New York, NY. 2016.
  3. Couto J.A., Greene A.K. Extensive Cervicofacial Arteriovenous Malformation. In: Richter GT, Suen JY (ed). Head and Neck Vascular Anomalies: A Practical Case-Based Approach. (Chapter 6.4, pp. 334-338). Plural Publishing; San Diego, CA. 2015.
Abstracts
  1. Banerjee A., Duran E., Couto J.A., Zhang Z., Espinoza L.A., Banerjee S.K., Baksi K., Banerjee D.K. Tunicamycin inhibits triple negative breast cancer progression. Cancer Res. 2011, Apr; 71(8 Suppl): Abstract nr 2095.
 
Awards
2017 Magna Cum Laude, University of Puerto Rico SOM
 
2017 Dr. Ramón Ruiz Arnau Clinical Research Award, University of Puerto Rico SOM
 
2013 Alpha Omega Alpha, Alpha Chapter, Puerto Rico
 
2009 Magna Cum Laude, University of Puerto Rico
 
 
 

Javier Couto

 
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