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John R. Frederick, M.D.
Cardiac Surgery

 
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Office:
Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

john.frederick@uphs.upenn.edu

 

John Frederick is a PGY7 in cardiac surgery. His laboratory interests include endothelial progenitor cell directed neovasculogenesis and tissue engineering.

 
Appointments
2009 - present Assistant Instructor in Surgery
 
2007 - 2009 Postdoctoral Researcher
 
2004 - 2007 Assistant Instructor in Surgery
 
 
 
 
 
Education/Training
2000 - 2004 University of Texas at Houston Medical School
 
1993 - 1997 University of Texas at Austin
B.A. in Economics, Minor in Zoology
 
 
 
 
 
 
Memberships/Societies
2006 - present Resident Member, American College of Surgeons
 
2009 - present Trainee Member, American Heart Association
 
 
 
 
 
 
 
Research
2007 - 2009 Cardiovascular Research laboratory of Y. Joseph Woo, M.D.
 
2001 - 2001 M.D. Anderson Cancer Center Summer Research Program
 
1998 - 2000

Center for Microvascular and Lymphatic Studies
University of Texas at Houston Medical School

 
 
 
 
Publications
Peer-Reviewed Publications
  1. Cox CS, Allen SJ, Butler D, Sauer H, Frederick J. Extracorporeal circulation exacerbates microvascular permeability after endotoxemia. Journal of Surgical Research. 2000 Jun1:91(1):50-5.
  2. Cox CS, Allen SJ, Sauer H, Frederick J. Effects of selectin-sialyl Lewis blockade on mesenteric microvascular permeability associated with cardiopulmonary bypass. Journal of Thoracic and Cardiovascular Surgery. 2000 Jun: 119(6):1255-61.
  3. Fitzpatrick JR, Frederick JR, Hsu VM, Kozin ED, O'Hara ML, Howell E, Dougherty D,McCormick RC, Laporte, CM, Cohen JE, Southerland KW, Howard, JL, Jessup ML, Morris RJ, Acker MA, Woo YJ. A risk score derived from preoperative data analysis predicts the need for biventricular mechanical circulatory support. J Heart Lung Transplant 2008;27:1286-92.
  4. Fitzpatrick JR, Frederick JR, Hiesinger W, Hsu VM, McCormick RC, Kozin ED, Laporte CM, O’Hara ML, Howell E, Dougherty D, Cohen JE, Southerland KW, Howard JL, Paulson EC, Acker MA, Morris RJ, Woo YJ. Early planned institution of biventricular mechanical circulatory support results in improved outcomes compared with delayed conversion of a left ventricular assist device to a biventricular assist device. J Thorac Cardiovasc Surg 2009;137(4):971-7.
  5. Fitzpatrick JR, Frederick JR, McCormick RC, Harris DA, Kim A, Muenzer JR, Gambogi JA, Liu JP, Paulson EC, Woo YJ. Tissue Engineered Pro-Angiogenic Fibroblast Scaffold Improves Myocardial Perfusion and Function and Limits Ventricular Remodeling Following Infarction. J Thorac Cardiovasc Surg 2010 (in press).
  6. Frederick JR, Fitzpatrick JR, McCormick RC, Harris DA, Kim AY, Muenzer JR, Marotta N, Smith MJ, Cohen JE, Hiesinger W, Atluri P, Woo YJ. Stromal Cell-Derived Factor-1a Activation of Tissue Engineered Endothelial Progenitor Cell Matrix Enhances Ventricular Function after Myocardial Infarction by Inducing Neovasculogenesis. Accepted, in press, Circulation 2010.
Abstracts
  1. Frederick J, Yasko A. Management and Outcome of Giant Cell Tumors of the Hands and Feet. Southern Orthopedic Association, April 6, 2002.
  2. Woo YJ, Southerland K, Frederick JR, Kotloff R, Hadjiliadis D, ChristieJ , Ahya V, Sager J, Szeto W, Blumenthal N, Cowie D, Bavaria J, Kaiser L, Pochettino A. The Penn Lung Transplant Experience: 538 Transplants over 15 years. American College of Chest Physicians, October 24, 2007.
  3. Fitzpatrick JR, Frederick JR, Hsu VM, Kozin ED, O'Hara ML, Howell E, McCormick RC, Laporte CM, Cohen JE, Southerland KA, Howard JL, Jessup ML, Morris RJ, Acker MA, Woo YJ. Preoperative parameters at the time of left ventricular assist device placement predict the need for biventricular mechanical support. 28th Annual Meeting of the International Society for Heart and Lung Transplantation. April 10, 2008. JHLT 2008; 27 2S: S93-S94.
  4. Fitzpatrick JR, Frederick JR, Hiesinger W, McCormick RC, Hsu VM, Kozin ED, O’Hara ML, Howell E, Cohen JE, Southerland KW, Howard JL, Nacke EA, LaPorte CM, Jessup ML, Morris RJ, Acker MA, Woo YJ. Critical Preoperative Data Predict the Need for Concurrent LVAD and RVAD Implantation, Avoiding Poor Outcomes Associated with Delayed Conversion of LVAD to BiVAD. 34th Annual Meeting of the Western Thoracic Surgical Association. June 25-28, 2008.
  5. Frederick JR, Southerland K , Fitzpatrick JR , McCormick RC, Blumenthal N, Szeto W, Pochettino A, Woo YJ. Impact of Bilateral Lung Transplantation and Cardiopulmonary Bypass on Survival in Patients with Idiopathic Pulmonary Fibrosis. American College of Surgeons 94th Annual Clinical Congress. October 12-16, 2008.
  6. Cohen JE, Atluri P, Harris DA, McCormick R, Kim A, Frederick JR, Fitzpatrick JR, Hiesinger W, Laporte CM, Smith MJ, Hsu VM, Patel AB, Woo YJ. Cripto Stimulates Myocardial Proliferation and Enhances Ventricular Function in Ischemic Cardiomyopathy. American Heart Association Scientific Sessions. October 9-12, 2008.
  7. Southerland KW, Frederick JR, Fitzpatrick JR, McCormick RC, Howard JL, Blumenthal N, Szeto WY, Pochettino A, Woo YJ. Preoperative FEV1 as an Indicator for the Use of Cardiopulmonary Bypass in Bilateral Lung Transplantation for Chronic Obstructive Pulmonary Disease. 4th Annual Academic Surgical Congress. February 3-6, 2009.
  8. Frederick JR, Fitzpatrick JR, McCormick RC, Harris DA, Kim A, Smith MJ, Laporte CM, Muenzer JR, Gambogi AJ, Woo YJ. Extracellular Matrix Scaffold Restores Ventricular Function by Attenuating Adverse Ventricular Remodeling after MyocardialInfarction. American College of Cardiology 58th Annual Scientific Session, March 29-31, 2009.
  9. Fitzpatrick JR, Frederick JR, McCormick RC, Harris DA, Kim A, Smith MJ, Laporte CM, Muenzer JR, Gambogi AJ, Woo YJ. Tissue Engineered Pro-Angiogenic Fibroblast Matrix Improves Myocardial Perfusion and Function and Limits Ventricular Remodeling following Infarction. 89th Annual Meeting of the American Association for Thoracic Surgery. May 10, 2009.
  10. Frederick JR, Fitzpatrick JR, McCormick RC, Harris DA, Kim AY, Muenzer JR, Smith MJ, Cohen JE, Atluri P, Woo YJ. Tissue Engineered Endothelial Progenitor Cell Construct Promotes Neovasculogenesis, Enhances Perfusion, and Improves Ventricular Function after Myocardial Infarction. American College of Surgeons 95th Annual Clinical Congress. October 11-15, 2009.
  11. Frederick JR, Fitzpatrick JR, McCormick RC, Harris DA, Kim AY, Muenzer JR, Murthy A, Hsiao PF, Prystowsky AD, Smith MJ, Cohen JE, Atluri P, Woo YJ. Stromal Cell-Derived Factor-1a Activation of Tissue Engineered Endothelial Progenitor Stem Cell Matrix Enhances Ventricular Function After Myocardial Infarction by Inducing Neovasculogenesis. American Heart Association Scientific Sesions 2009. November 14- 18, 2009.
  12. Hiesinger W, Frederick JR, Fitzpatrick JR, Atluri P, Levit RD, McCormick RC, Marotta NA, Muenzer JR, Kim AY, Woo YJ. Spliced SDF-1 Analog Stimulates Endothelial Progenitor Cell Migration and Improves Cardiac Function In a Dose-Dependent Manner Following Myocardial Infarction. 36th Annual Meeting of the Western Thoracic Surgical Association. June 23-26, 2010.
Chapters
  1. Frederick JR, Kaiser LR. Pulmonary Physiology and Thoracic Disease. The Surgical Review, Third Edition. Lippincott, William & Wilkins, Philadelphia, PA, 2009.
  2. Abdullah I, Frederick JR, Resnick A, Morris JB. Hernias. The Surgical Review, Third Edition. Lippincott, William & Wilkins, Philadelphia, PA, 2009.
Books
  1. Porrett P, Roses R, Frederick JR, Kaiser LR. Editors. The Surgical Review, Third Edition. Lippincott Williams & Wilkins. Philadelphia, PA. 2009.

Dr. John Frederick

 
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