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Arjun Nimalan Jeganathan, M.D.
General Surgery Resident

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Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

  Arjun Jeganathan is a PGY-7 General Surgery resident at the University of Pennsylvania, in his final year of residency training. He spent two years as a Harrison Surgical Research Fellow in the laboratory of Dr. Anil K. Rustgi, elucidating molecular biology pathways in the tumor microenvironment of colon cancer. Clinical interests include outcomes within malignant colorectal disease.
2016 - present Instructor in Surgery
2010 - 2016 Assistant Instructor in Surgery
2013 - 2015 Postdoctoral Researcher, Division of Gastroenterology
University of Pennsylvania
2012 - 2017 Resident in General Surgery
Philadelphia, Pennsylvania
2011 - 2012 Intern in General Surgery
Philadelphia, Pennsylvania
2006 - 2010 MD – Tufts University
Boston, Massachusetts
2000 - 2004 BA – Biology, Chemistry – University of Pennsylvania
Philadelphia, Pennsylvania
2014 - present American Society of Colon & Rectal Surgeons (ASCRS)
2010 - present American College of Surgeons (ACS)
2010 Alpha Omega Alpha

Harrison Surgical Research Fellow, Division of Gastroenterology, Philadelphia, Pennsylvania
Researcher, Dr. Anil K. Rustgi
Elucidated molecular biology pathways in the tumor microenvironment of colon cancer

05/2007 – 08/2007
Harold Williams Research Fellowship, Boston, Massachusetts
Researcher, Dr. Richard B. Freeman, Jr.
Studied the effects of ischemia-reperfusion injury on the biliary system in transplanted liver allografts.
06/2004 – 07/2006
University of Pennsylvania, Department of Surgery, Philadelphia, Pennsylvania
Undergraduate Researcher, Drs. Ali Naji and Hooman Noorchashm
Characterized the regulation of T-lymphocyte homeostasis and activation profile in the context of transplant rejection.
09/2003 – 05/2004
University of Pennsylvania, Department of Biology, Philadelphia, Pennsylvania
Undergraduate Researcher, Drs. Hooman Noorchashm and Paul D. Sniegowski
Studied the effects of thymocyte development of imprinting of peripheral lymphocyte compartment size and proliferative capcacity.
  1. Newton AD, Li J, Jeganathan A, Mahmoud N, Epstein A, Paulson E. A nomogram to predict lymph node positivity following neoadjuvant chemoradiation in locally advanced rectal cancer. Dis Colon Rectum (2016); 59(8):710-7.
  2. Jeganathan AN, Shanmugan S, Bleier JI, Hall GM, Paulson EC. Colorectal specialization increases lymph node yield: evidence from a national database. Ann Surg Oncol (2016); 23(7):2258-65.
  3. Hall GM, Shanmugan S, Bleier JI, Jeganathan AN, Epstein A, Paulson EC. Colorectal specialization and survival in colorectal cancer. Colorectal Dis (2015); 18(2):O51-60.
  4. Ecker BL, Paulson EC, Datta J, Jeganathan AN, Aarons C, Kelz RR, Mahmoud NN. Lymph node identification following neoadjuvant therapy in rectal cancer: a stage-stratified analysis using the surveillance, epidemiology, and end results (SEER)-Medicare database. J Surg Oncol (2015); 112(4):415-20.
  5. Madison BB, Jeganathan AN, Mizuno R, Winslow MM, Castells A, Cuatrecasas M, Rustgi AK. Let-7 represses carcinogenesis and a stem cell phenotype in the intestine via regulation of Hmga2. PLoS Genet (2015); 11(8):e1005408.
  6. Reed AJ, Zarrabi Y, Perate AL, Jeganathan A, Naji A, Noorchashm H. The frequency of double-positive thymocytes expressing an alpha-beta TCR clonotype regulates peripheral CD4 T cell compartment homeostasis. Immunology (2005); 116(3):400-7.
  7. Reed AJ, Noorchashm H, Rostami SY, Zarrabi Y, Perate AR, Jeganathan AN, Caton AJ, Naji A. Alloreactive CD4 T cell activation in vivo: an autonomous function of the indirect pathway of alloantigen presentation. J Immunol (2003); 171(12):6502-9.
Textbook Chapters
  1. Jeganathan AN, Drebin JA. Tumor Biology, In The Surgical Review: An Integrated Basic and Clinical Science Study Guide, 4th Ed (2015). Porrett PM, Atluri P, Karakousis GC, Roses RE, Drebin JA (Eds). Philadephia, PA: Lippincott Williams & Wilkins.
  2. Jeganathan AN, Cannon JW, Bleier J. Anal & Perineal Injuries, in Clinics of Colon and Rectal Surgery (2016) – submitted. 
2010 George L. Howland Prize, Tufts University School of Medicine
2010 Martin J. Loeb Memorial Prize in Surgery, Tufts University School of Medicine
2010 Alpha Omega Alpha (AOA) Honor Society

Dr. Arjun Jeganathan

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