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Jane J. Keating, M.D.
General Surgery Resident

 
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Office:
Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

Jane.Keating@uphs.upenn.edu

 

Dr. Keating is currently a PGY6 General Surgery Resident at the University of Pennsylvania. While in the lab, she completed a Harrison Post-Doctoral Research Fellowship where she studied intraoperative molecular imaging focusing most of her research on solid tumors. She has presented and published extensively in this area and is working to apply this research in the setting of intraoperative imaging of bowel and anastomotic perfusion.  She plans to pursue a career in acute care surgery.

 
Appointments
2014 - 2016 Postdoctoral Researcher
 
2011 - present Assistant Instructor in Surgery
 
 
 
 
 
 
 
 
Education/Training
07/01/2014 - present University of Pennsylvania Hospital, Philadelphia, Pennsylvania
Perelman School of Medicine          
Post-doctoral Research Fellow, Surgery
 
06/15/2011 - present University of Pennsylvania Hospital, Philadelphia, Pennsylvania
Perelman School of Medicine
Resident, General Surgery
 
08/2007 - 06/2011  Emory University School of Medicine, Atlanta, Georgia
Doctor of Medicine (3.98 GPA)
 
08/2002 - 06/2006 Emory University, Atlanta, Georgia
Summa cum Laude, Phi Beta Kappa (3.98 GPA)
Bachelor of Science, Neuroscience
 
Memberships/Societies
 
Honorary
  • Phi Beta Kapa
  • Nu Rho Psi
Professional
  • American College of Surgeons
  • Society of Thoracic Surgeons
  • American Medical Association
  • Society of Surgical Oncology
 
 
 
Research

07/2014 – Present      
Department of Surgery, University of Pennsylvania, Philadelphia, Pennsylvania
Role: Research Fellow PI:Dr. Sunil Singhal
Currently working to develop intraoperative-imaging techniques to improve the complete resection of primary and metastatic cancer.

04/2010 – 08/2010     
Department of Cardiothoracic Surgery, Emory University, Atlanta, Georgia
Role: Student Researcher  PI: Drs. Mary Wagner and Paul Kishborn Generated animal models of palliated hypoplastic left heart syndrome by performing and assisting in pulmonary artery banding procedures.

08/2008 – 11/2008     
Department of Trauma Surgery, Emory University, Atlanta, Georgia
Role: Student Researcher  PI: Dr. Jana Mcleod
Evaluated patients with life threatening trauma for evidence of early trauma induced coagulopathy.

05/2005 – 05/2006     
Yerkes Primate Research Center, Emory University, Atlanta, Georgia
Role: Research assistant  PI: Dr. Mar Sanchez 
Study of neurobiological systems that control stress physiology and emotion regulation in nonhuman primates. Analyzed the stress-induced hypothalamic pituitary adrenal response of rhesus macaques who had been noted to be either abused or abandoned by their mother at an early age.

 
Publications
Original Articles
  1. Clifton MS, Heiss KF, Keating J, Mackay G, Ricketts RR. “Use of tissue expanders in the repair of complex abdominal wall defects. Journal of Pediatric Surgery.” 2011 Feb;46(2):372-7. PMID: 21292090.
  2. Keating J, Simsic JM, Kogon BE, Kanter KR, Huckaby J, Kilgo PD, Kirshbom PM. “Impact of early fundoplication or gastrostomy tube on midterm outcomes for patients with single ventricle.” Journal of Thoracic and Cardiovascular Surgery. 2012 Apr;143(4):891-5. PMID: 22284624.
  3. Keating J, Kennedy GT, Singhal S. “Identification of a subcentimeter pulmonary adenocarcinoma using intraoperative near-infrared imaging during video-assisted thoracoscopic surgery.” Journal of Thoracic and Cardiovascular Surgery. 2015 Mar;149(3):e51-3. PMID: 25827389.
  4. Holt D, Parthasarathy AB, Okusanya O, Keating J, Venegas O, Deshpande C, Karakousis G, Madajewski B, Durham A, Nie S, Yodh AG, Singhal S. “Intraoperative near-infrared fluorescence imaging and spectroscopy identifies residual tumor cells in wounds.” Journal of Biolmedical Optics. 2015 Jul;20(7):76002. PMID: 26160347.
  5. Keating J, Okusanya OT, De Jesus E, Judy R, Jiang J, Deshpande C, Nie S, Low P, Singhal S. “Intraoperative Molecular Imaging of Lung Adenocarcinoma Can Identify Residual Tumor Cells at the Surgical Margins.” Molecular Imaging and Biology. 2015 Jul 31. PMID: 26228697.
  6. Jiang JX, Keating J, Jesus EM, Judy RP, Madajewski B, Venegas O, Okusanya OT, Singhal S. “Optimization of the enhanced permeability and retention effect for near-infrared imaging of solid tumors with indocyanine green.” Am J Nucl Med Mol Imaging. 2015 Jun 15;5(4):390-400. PMID: 26269776.
  7. Kennedy GT, Okusanya OT, Keating J, Heitjan DF, Deshpande C, Litzky LA, Albelda SM, Drebin JA, Nie S, Low PS, Singhal S. “The Optical Biopsy: A Novel Technique for Rapid Intraoperative Diagnosis of Primary Pulmonary Adenocarcinomas.” Annals of Surgery. 2015 Oct;262(4):602-9. PMID: 26366539.
  8. De Jesus E, Keating J, Kularatne SA, Jiang J, Judy R, Predina J, Nie S, Low P, Singhal S. “Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging.” International Journal of Molecular Imaging. 2015;2015:469047. PMID: 26491562.
  9. Guzzo TJ, Jiang J, Keating J, DeJesus E, Judy R, Nie S, Low P, Lal P, Singhal S. “Intraoperative Molecular Diagnostic Imaging Can Identify Renal Cell Carcinoma.” Journal of Urology. 2016 Mar;195(3):748-55. PMID: 26541080.
  10. Judy RP, Keating J, DeJesus EM, Jiang JX, Okusanya OT, Nie S, Holt DE, Arlauckas SP, Low PS, Delikatny EJ, Singhal S. “Quantification of tumor fluorescence during intraoperative optical cancer imaging.” Scientific Reports. 2015 Nov 13;5:16208. PMID: 26563091.
  11. Keating J, Nims S, Venegas O, Jiang J, Holt D, Kucharczuk JC, Deshpande C, Singhal S. “Intraoperative imaging identifies thymoma margins following neoadjuvant chemotherapy.” Oncotarget. 2016 Jan 19;7(3):3059-67. PMID: 26689990.
  12. Predina JD, Keating J, Patel N, Nims S, Singhal S. “Clinical implications of positive margins following non-small cell lung cancer surgery.”  Journal of Surgical Oncology. 2015 Dec 30. PMID: 26719121.
  13. Keating J, Kennedy GT, Datta J, Schuricht A. “Outcomes of 157 V-Patch(TM) Implants in the Repair of Umbilical, Epigastric, and Incisional Hernias.” American Surgeon. 2016 Jan;82(1):6-10. PMID: 26802839.
  14. Keating J, Tchou J, Okusanya O, Fisher C, Batiste R, Jiang J, Kennedy G, Nie S, Singhal S.  “Identification of breast cancer margins using intraoperative near-infrared imaging.”  Journal of Surgical Oncology. 2016 Feb 4. PMID: 26843131.
  15. Keating J, Singhal S. “Novel Methods of Intraoperative Localization and Margin Assessment of Pulmonary Nodules.” Seminars in Thoracic and Cardiovascular Surgery. 2016 Feb 4.
  16. Keating J, Judy R, Newton A, Singhal S. “Near-infrared operating lamp for intraoperative molecular imaging of a mediastinal tumor.” BMC Medical Imaging. 2016 Feb 17; 16(1):15. PMID:26883511.
  17. Keating J, Fisher C, Batiste R, Singhal S. “Advances in Intraoperative Margin Assessment for Breast Cancer.” Current Surgery Reports. 2016 March 26; 4:15.
  18. Predina JD, Keating J, Venegas O, Nims S, Singhal S. “Neoadjuvant intratumoral immuno-gene therapy for non-small cell lung cancer.” Discovery Medicine.  2016 Apr; 21(116):275-81. PMID: 27232513.
  19. Lee J, Thawani J, Pierce J, Zeh R, Martinez-Lage M, Learned K, Chanin M, Venegas O, Nims S, Keating J, Singhal S. “Intraoperative Near-Infrared Optical Imagign Can Localize Gadolinium-Enhanced Gliomas During Surgery.” Neurosurgery.  Accepted for publication July, 2016.
  20. Keating J, Newton A, Venegas O, Nims S, Zeh R, Predina J, Deshpande C, Kucharczuk J, Nie S, Delikatny J, Singhal S. “Near-Infrared Intraoperative Molecular Imaging Can Locate Metastases to the Lung.” Journal of Thoracic and Cardiovascular Surgery.  Accepted for publication July, 2016.
  21. Keating J, Predina J, Troutman G, Nims S, Venegas O, Deshpande C, Singhal S. “Near-Infrared Optical Imaging During Resection of Mediastinal Thymomas Identifies Tumor Margins.” Journal of Thoracic and Carciovascular Surgery.  Submitted after abstract presentation June, 2016.
  22. Keating J, Runge J, Singhal S, Nims S, Venegas O, Durham A, Swain G, Nie S, Low P, Holt D. “Intraoperative Near-Infrared Fluorescence Imaging Targeting Folate Receptors Identifies Lung Cancer in a Large Animal Model.” Submitted to Cancer May, 2016.
Oral Presentations
  1. Keating J, Simsic J, Kogon B, Kanter K, Huckaby J, Kilgo P, Kirshbom P. Impact of Surgery for Reflux or Feeding Intolerance on Mid-term Outcomes for Single Ventricle Patients. Western Thoracic Surgical Association Annual Meeting, June, 2011.
  2. Keating J, Olugbenga O, Jiang J, De Jesus E, Judy R, Singhal S. Intraoperative Molecular Imaging For the Complete Resection of Mediastinal Tumors.  Philadelphia Academy of Surgery. Podium Presentation First Prize Winner. February 9, 2015.
  3. Keating J, Jiang J, De Jesus E, Judy R, Singhal S. Intraoperative molecular imaging of pre-treated mediastinal tumors is feasible. 95th Annual Meeting of the American Association for Thoracic Surgery, April 28, 2015.
  4. Kennedy G, Okusanya O, Heitjan D, Deshpande C, Litzky L, Keating J, Albelda S, Nie S, Low P, Drebin J, Singhal S. Intraoperative Molecular Imaging Provides Rapid and Accurate Diagnosis of Primary Pulmonary Adenocarcinoma. American Surgical Association 135th Annual Meeting. April 24, 2015.
  5. Guzzo T, Keating J, Jiang J, De Jesus E, Singhal S. Intraoperative Molecular Diagnostic Imaging Can Identify Renal Cell Carcinoma During Nephrectomy. American Urological Association Annual Meeting. May 17, 2015.
  6. Keating J, Judy R, Jiang J, De Jesus E, Crisman, E, Singhal S. Intraoperative Molecular Imaging for Detecting Subcentimeter Pulmonary Tumors. American College of Surgeons: 2015 Clinical Congress. October 5, 2015, Chicago, IL.
  7. Keating J, Nims S, Judy R, Jiang R, Singhal S. Near-Infrared Intraoperative Molecular Imaging Localizes Metastases to the Lung. Society of Thoracic Surgeons 52nd Annual Meeting, January 25, 2016, Phoenix, AZ.
  8. Predina JD, Keating J, Albelda S, Singhals. Harnessing the Immune System—Adjuvant Immunotherapy for Thoracic Malignancies. Philadelphia Academy of Surgery Resident Research Competition. Philadelphia, PA, USA. February 2, 2016.
  9. Keating J, Nims S, Venegas O, Deshpande C, Nie, S, Low P, Singhal S. Intraoperative Molecular Imaging Of Pulmonary Adenocarcinomas Using A Targeted Near-Infrared Dye. 11th Annual Academic Surgical Congress. February 3, 2016, Jaxonville, FL.
  10. Keating J, Predina J, Venegas O, Nims S, Kucharczuk J, Singhal S. Indocyanine Green and Intraoperative Imaging Detects Residual Disease Following Resection of Malignant Pleural Mesothelioma. 13th International Conference of the International Mesothelioma Interest Group, May, 2016.
  11. Predina J, Keating J, Singhal S, Albelda S.  Multi-modal Adjuvant Immmuno-gene therapy for Malignant Pleural Mesothelioma. 13th Meeting of the International Mesothelioma Interest Group. Birmingham, England. May 2-4, 2016.
  12. Keating J, Predina J, Nims S, Venegas O, Deshpande C, Kucharczuk J, Singhal S.  Near-Infrared Optical Imaging During Resection of Mediastinal Thymomas. Improves Assessment of Surgical Margins. 96th Meeting of the American Association of Thoracic Surgery.  Baltimore, MD, USA. May 14-16, 2016.
  13. Predina J, Okusanya, Keating J, Singhal S. Optimization of Image Capture Properties for Intraoperative Molecular Imaging of Lung Adenocarcinoma. 96th Meeting of the American Association of Thoracic Surgery.  Baltimore, MD, USA. May 14-16, 2016.
  14. Predina J, Venegas O, Keating J, Nims S, Singhal S.  Intraoperative Molecular Imaging Enhances the Surgeon’s Ability to Identify Residual Disease during Esophageal Cancer Surgery.  2017 American College of Surgeons Clinical Congress. Washington, DC, USA (accepted).
Poster Presentations
  1. Schuricht A, Keating J. Recurrence Rates of Laparoscopic Intraperitoneal Onlay Mesh (IPOM) Technique Inguinal Hernia Repairs When Performed Alone Vs. At The Time of Robotic Assisted Laparoscopic Prostatectomy. Annual Hernia Repair, March 13, 2014.
  2. Schuricht A, Keating J. Outcomes of 157 V-Patch Implants in the Repair of Umbilical, Epigastric, and Incisional Hernias. Annual Hernia Repair, March 13, 2014.
  3. Keating J, Crisman E, Jiang J, Judy R, De Jesus E, Singhal S. Indocyanine green (ICG) extraction and quantification for intraoperative molecular imaging of tumors. Society of Nuclear Medicine and Molecular Imaging Annual Meeting, June 8, 2015, Baltimore, MD.
  4. Keating J, Kennedy G, Okusanya O, Deshpande D, Nie S, Low P, Singhal S. Diagnosis of Pulmonary Adenocarcinomas Using Intraoperative Molecular Imaging. 21st Annual University of Pennsylvania Respiration Research Retreat, June 19, 2015.
  5. Keating J, Judy R, Jiang J, De Jesus E, Crisman E, Singhal S. Intraoperative Molecular Imaging For Detecting Subcentimeter Pulmonary Tumors. Academy of Women Surgeons Fall Conference. October 4, 2015.
  6. Keating J, Predina J, Nims S, Venegas O, Singhal S. Near-Infrared Intraoperative Molecular Imaging Identifies Mesothelioma During Pleurectomy. 69th Annual Cancer Symposium Society of Surgical Oncology: Annual Cancer Symposium Poster Contest, March 3, 2016.
  7. Keating J, Predina J, Nims S, Venegas O, Deshpande C, Singhal S, Kucharczuk J. Folate-Targeted Dye Localizes Subpleural Pulmonary Adenocarcinomas During Video-Assisted Thoracoscopic Resection.  General Thoracic Surgery Club, March 10, 2016.
  8. Predina J, Keating J, Singhal S, Kucharczuk J. Harnessing the Immune System—Adjuvant Immunotherapy for Thoracic Malignancies.  The 29th Annual Meeting of the General Thoracic Surgical Club.  Tucson, AZ, USA.  March 9-12, 2016.
 
Awards
2015 First Place, Podium Presentation Philadelphia Academy of Surgery
 
2005 Nu Rho Psi, neuroscience honor society
 
2004 Phi Beta Kappa
 
2003 - 2006 Captain – Emory Women’s Rowing
 
2003 Emory Scholar
 
2003 Most Valuable Player – Emory Women’s Rowing

Dr. Jane Keating

 
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