penn medicine
penn surgery
penn surgery home penn surgery clinical penn surgery education penn surgery research penn surgery administration

Andrew J. Sinnamon, M.D.
General Surgery Resident

 
  • Profile Home
  • Appointments
  • Education
  • Societies
  • Research
  • Publications
  • Awards

Office:
Department of Surgery
4 Maloney
3400 Spruce Street
Philadelphia, PA 19104

Administrative Telephone: 215-662-6156

Contact Information (internal use only)

Andrew.Sinnamon@uphs.upenn.edu

 

Andrew Sinnamon is currently a PGY-5 resident in General Surgery and currently in his second year of research under Dr. Giorgos Karakousis. He is also currently pursuing a Masters in Clinical Epidemiology. His interests include oncologic and gastrointestinal surgery and intends to pursue a career in surgical oncology.

 

 
Appointments
2016 - present Postdoctoral Researcher
 
2013 - present Assistant Instructor of Surgery
 
 
 
 
 
 
 
 
Education/Training
2016 - present MSCE candidate, University of Pennsylvania
 
2009 - 2013 MD - University of Pennsylvania School of Medicine
 
2005 - 2009  BS - Biochemistry and Molecular Biology
Pennsylvania State University
 
 
 
 
 
 
Memberships/Societies
  • American College of Surgeons
  • Phi Beta Kappa
 
 
 
 
 
 
 
 
 
Research
University of Pennsylvania School of Medicine 2016 – Present
Giorgos Karakousis, MD, Principal Investigator and Department of Endocrine and Oncologic Surgery
Research fellow currently involved in clinical research projects concerning melanomas, sarcomas, and other tumors.
 
University of Pennsylvania School of Medicine 2012 – 2013
Rachel Kelz, MD, MSCE, Principal Investigator
Investigated gender-related differences in surgical outcomes following lower extremity revascularization.
 
University of Pennsylvania School of Medicine 2010
Lawrence Brass, MD, PhD, Principal Investigator
Studied the intracellular regulation pathways of platelet activation. Research was supported by the 2010 American Society of Hematology Trainee Award and was presented as a poster at the 2010 American Society of Hematology Annual Meeting.
 
Pennsylvania State University 2006 – 2009
B. Frank Pugh, PhD, Thesis Advisor
Studied genomic binding locations of the known transcription factors of Saccharomyces cerevisiae using chromatin immunoprecipitation coupled to DNA microarrays (ChIP-chip). Research culminated in honors thesis, entitled “Genome-Wide Movement of Transcriptional Machinery in Response to Heat Shock”
 
Publications
Peer-reviewed Manuscripts
  1. Sinnamon AJ, Sharon CE, Song Y, Neuwirth MG, Gimotty PA, Elder DE, Xu X, Fraker DL, Karakousis GC. The Prognostic Significance of Tumor-Infiltrating Lymphocytes for Primary Melanoma Varies by Gender. Under review
  2. Sinnamon AJ, Neuwirth MG, Gimotty PA, Gangadhar T, Amaravadi R, Schuchter L, Karakousis GC. Improved Survival in Stage IV Melanoma: A Nationwide Analysis in the Modern Era of Immune Checkpoint Inhibition and Targeted Therapy. Under review
  3. Sinnamon AJ, Neuwirth MG, Vining CC, Sharoky CE, Yang YX, Kelz RR, Fraker DL, Roses RE, Karakousis GC. Prophylactic cholecystectomy at time of surgery for small bowel neuroendocrine tumor does not increase post-operative morbidity. Under review
  4. Neuwirth MG, Bierema C, Sinnamon AJ, Fraker DL, Kelz RR, Roses RE, Karakousis GC. Trends in Major Abdominal Surgery for Cancer in Octogenarians; has there been a change in patient selection? Cancer. In revision
  5. Neuwirth MG, Song Y, Sinnamon AJ, Fraker DL, Zager JS, Karakousis GC. Isolated Limb Perfusion and Infusion for Extremity Soft Tissue Sarcoma: A Contemporary Systematic Review and Meta-Analysis. Annals of Surgical Oncology. In revision
    Sinnamon AJ, Neuwirth MG, Yalamanchi P, Gimotty PA, Elder DE, Xu X, Kelz RR, Roses RE, Chu EY, Ming ME, Fraker DL, Karakousis GC. Association Between Patient Age and Lymph Node Positivity in Thin Melanoma. JAMA Dermatology. 2017 Jul 19. [Epub ahead of print]
  6. Sharoky CE, Baily EA, Sellers MM, Kaufman EJ, Sinnamon AJ, Wirtalla CJ, Holena DN, Kelz RR. Outcomes of Hospitalized Patients Undergoing Emergency General Surgery Remote from Admission. Surgery. 2017 Jul 6. [Epub ahead of print]
  7. Sinnamon AJ, Neuwirth MG, Bartlett EK, Zaheer S, Etherington MS, Xu X, Elder DE, Czerniecki BJ, Fraker DL, Karakousis GC. Predictors of False Negative Sentinel Lymph Node Biopsy in Trunk and Extremity Melanoma. Journal of Surgical Oncology. J Surg Oncol. 2017 Jun 26. [Epub ahead of print]
  8. Vining CC,* Sinnamon AJ,* Neuwirth MG, Ecker BL, Kelz RR, Fraker DL, Roses RE, Karakousis GC. Adjuvant Chemotherapy in Resectable Synovial Sarcoma. Journal of Surgical Oncology. 2017 Jun 5. [Epub ahead of print]
    * co-first author
  9. Ecker BL, Peters MG, McMillan MT, Sinnamon AJ, Zhang PJ, Kelz RR, Roses RE, Drebin JA, Fraker DL, Karakousis GC. Implications of Lymph Node Evaluation in the Management of Resectable Soft Tissue Sarcoma. Ann Surg Oncol. 2017 Feb; 24(2):425-433
  10. Ecker BL, Peters MG, McMillan MT, Sinnamon AJ, Zhang PJ, Fraker DL, Levin WP, Roses RE, Karakousis GK. Preoperative radiotherapy in the management of retroperitoneal liposarcoma. Br J Surg. 2016 Dec; 103(13): 1839-1846
  11. Sinnamon AJ, Neuwirth MG, McMillan MT, Ecker BL, Bartlett EK, Zhang PJ, Kelz RR, Fraker DL, Roses RE, Karakousis GC. A prognostic model for resectable soft tissue and cutaneous angiosarcoma. J Surg Oncol. 2016 Oct;114(5):557-563.
  12. Ma P, Ou K, Sinnamon AJ, Jiang H, Siderovski DP, Brass LF. Modulating platelet reactivity through control of RGS18 availability. Blood. 2015 Dec 10;126(24):2611-20.
  13. Ma P, Foote DC, Sinnamon AJ, Brass LF. Dissociation of SHP-1 from spinophilin during platelet activation exposes an inhibitory binding site for protein phosphatase-1 (PP1). PLoS One. 2015 Mar 18;10(3):e0119496.
  14. Sinnamon AJ, Sonnenberg EM, Bartlett EK, Meise CK, Wang GJ, Kelz RR. The influence of socioeconomic factors on gender disparities in lower extremity bypass. J Surg Res. 2014 May 15;188(2):537-44
  15. Bartlett EK, Gimotty PA, Sinnamon AJ, Wachtel H, Roses RE, Schuchter L, Xu X, Elder DE, Ming M, Elenitsas R, Guerry D, Kelz RR, Czerniecki BJ, Fraker DL, Karakousis GC. Clark level risk stratifies patients with mitogenic thin melanomas for sentinel lymph node biopsy. Ann Surg Oncol. 2014 Feb;21(2):643-9.
  16. Ma P, Cierniewska A, Signarvic R, Cieslak M, Kong H, Sinnamon AJ, Neubig RR, Newman DK, Stalker TJ, Brass LF. A newly identified complex of spinophilin and the tyrosine phosphatase, SHP-1, modulates platelet activation by regulating G protein-dependent signaling. Blood. 2012 Feb 23
  17. Venters BJ, Wachi S, Mavrich TN, Andersen BE, Jena P, Sinnamon AJ, Jain P, Rolleri NS, Jiang C, Hemeryck-Walsh C, Pugh BF. A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell. 2011 Feb 18
Abstracts
  1. Sinnamon AJ, Neuwirth MG, Sharoky CE, Kelz RR, Fraker DL, Roses RE, Karakousis GC. Concurrent Cholecystectomy at time of Surgery for Small Bowel Neuroendocrine Tumor is Not Associated with Increased Morbidity (Podium Presentation). American College of Surgeons Clinical Congress 2017. 2017 Oct
  2. Sinnamon AJ, Neuwirth MG, Sharoky CE, Kelz RR, Roses RE, Fraker DL, Karakousis GC. Adherence to Current Guidelines for Nodal Evaluation in Thin Melanoma is Associated with Prolonged Survival (Podium Presentation). Society of Surgical Oncology 2017. 2016 Sep
  3. Sinnamon AJ, Zaheer S, Ben-Maimon S, Neuwirth MG, Cohen DL, Nathanson KL, Karakousis GC, Woo EY, Jackson BM, Roses RE, Fraker DL. Management of Extraadrenal Abdominal Paraganglioma with Vascular Involvement (Poster Presentation). Society of Surgical Oncology 2017. 2016 Sep
  4. Neuwirth MG, Sinnamon AJ, Roses RE, Kelz RR, Fraker DL, Karakousis GC. Age-dependent variability in the prognostic utility of sentinel lymph no biopsy in patients with melanoma. Society of Surgical Oncology 2017. 2016 Sep
  5. Sinnamon AJ, Neuwirth MG, Ecker BL, Gangadhar T, Amaravadi R, Schuchter L, Karakousis GC. National management trends and outcomes in advanced melanoma in a contemporary cohort (Conference abstract). Pigment Cell and Melanoma Research 2017
  6. Neuwirth MG, Sinnamon AJ, Kelz RR, Karakousis GC, Lee MK. Morbidity and mortality for patients with sinistral portal hypertension undergoing splenectomy. Academic Surgical Congress 2017. 2016 Aug
  7. Sharoky CE, Bailey EA, Sellers MM, Sinnamon AJ, Wirtalla C, Holena DN, Kelz RR. Predicting Outcomes in Hospitalized Patients Requiring Emergency General Surgery. Academic Surgical Congress 2017. 2016 Aug
  8. Neuwirth MG, Sinnamon AJ, Fraker DL, Kelz RR, Roses RE, Karakousis GC. Trends in major abdominal surgery for cancer in octogenarians. Academic Surgical Congress 2017. 2016 Aug
  9. Sinnamon AJ, Neuwirth MG, Hoffman RL, Elder DE, Xu X, Kelz RR, Roses RE, Fraker DL, Karakousis GC. Age is an Important Risk Stratifier for Lymph Node Metastasis in Patients with Thin Melanoma (Podium Presentation). Academic Surgical Congress 2017. 2016 Aug
  10. Vining CC, Sinnamon AJ, Neuwirth MG, Ecker BL, Kelz RR, Fraker DL, Roses RE, Karakousis GC. The Effect of Adjuvant Chemotherapy on Overall Survival in Patients with Synovial Sarcoma. Academic Surgical Congress 2017. 2016 Aug
  11. Bartlett EK, Gimotty P,  Sinnamon AJ, Wachtel H, Roses R, Schuchter LM, Xu X, Elder DE, Ming ME, Guerry D, Kelz RR, MD, Czerniecki BJ, Fraker DL, Karakousis GC. Sentinel Lymph Node Biopsy in Patients with Thin (≤1 mm) Melanoma. Society of Surgical Oncology 2013. 2012 Sep
  12. Bartlett EK, Sinnamon AJ, Wachtel H, Elder DE, Xu X, Schuchter LM, Ming ME, Gimotty P, Roses R, Czerniecki BJ, Kelz RR, Fraker DL, Karakousis GC. Sentinel Lymph Node Biopsy in Patients with Very Thin (<.76mm) Melanomas. Academic Surgical Congress 2013. 2012 Aug
  13. Ma P, Cierniewska A, Signarvic R, Sinnamon AJ, Cieslak M, Stalker TJ, Brass LF. Discovery of a New Signaling Complex Based on Spinophilin that Regulates Platelet Activation in vitro and in vivo. Blood 2010 116:21
  14. Sinnamon AJ, Ma P, Brass LF. Poster presentation: Agonist-induced binding of the regulatory scaffold protein spinophilin to protein phosphatase-1 in platelets (Poster Presentation). American Society of Hematology Annual Meeting 2010. Nov 2010.
Chapters
  1. Vining CC, Sinnamon AJ, Karakousis GC. Merkel Cell Carcinoma. In Complex General Surgical Oncology. Decker Intellectual Properties, 2016. Online
  2. Sinnamon AJ and Kucharczuk JC. The Esophagus. In The Surgical Review, 4th Ed. Philadelphia: Lippincott Williams and Wilkins, 2015. Print.
 
Awards
 
 
 
 
 
 
 
 
 
 

Dr. Andrew Sinnamon

 
footer Terms of Use Legal Disclaimer Site Map Contact Us Financial Assistance About Penn Medicine Privacy Statement
penn medicine