penn surgery
penn surgery home penn surgery clinical penn surgery education penn surgery research penn surgery administration
Cardiovascular Research Laboratory
Harrison Department of Surgical Research
Y. Joseph Woo, M.D.



H. Lee Sweeney, Ph.D. is the William Maul Measey Professor and Chairman of Physiology. His research focuses on muscle physiology and he has a particular interest in hypertrophic cardiomyopathy. A link to his bio can be found here. Dr. Sweeney and Dr. Ken Margulies are co-directors of the Myocyte Biology and Heart Failure Core of the Penn Cardiovascular Institute.

Dennis Discher, Ph.D. is a Professor and holds appointments in the School of Engineering and Applied Science (Departments of Chemical and Biomolecular Engineering, Mechanical Engineering, and Bioengineering). His research focuses on membrane and interface aspects of cells, relevant biomolecules, and self-assembling polymers for novel material and drug delivery nano-systems. Dr. Discher uses and develops single molecule and single cell manipulation methods, microscopies, molecular and cell biological systems & expression, computational statistical mechanics approaches, and appropriate field theories. Discher Lab link.

William Lee, M.D. Ph.D. is Associate Professor in the Department of Medicine, Division of Hematology/Oncology. His extensive knowledge of tumor angiogenesis makes him a valuable collaborator in the angiogenesis section of our basic science research. Follow this link.

Robert C. Gorman, M.D. is Associate Professor of Surgery in the Department of Surgery, Division of Cardiac Surgery. Dr. Gorman’s clinical interests include aortic surgery (aneurysms & dissections), mitral valve procedures (repair & replacement), esophageal surgery. Research interests include new surgical and medical strategies for the treatment of congestive heart failure, ischemic mitral regurgitation, organ preservation & myocardial protection, mitral valuloplasty prosthesis design, and pathogensis of aortic aneurysm. Follow this link to the Gorman Lab Web Site.

Robert L. Wilensky, M.D. is Professor of Medicine in the Division of Cardiovascular Medicine at the Hospital of the University of Pennsylvania, and Director of Interventional Cardiology Research. He has a large animal laboratory dedicated to evaluation of new devices and treatment of atherosclerosis and myocardial infarction. Follow this link.

Kenneth Margulies, M.D. is an associate professor in the Department of Medicine, Division of Cardiovascular Medicine. Besides continuing a busy clinical practice focusing on the management of patients with advanced heart failure, he maintains an active basic science research lab. His lab is focuses on myocardial remodeling and reverse remodeling, heart failure with preserved ejection fraction, E-C coupling and regulation of contractility, endogenous cardiac repair, and natriuretic peptide biology. A link to his bio can be found here.



penn medicine