Current Endeavors Include:
Mechanical Modeling of Aortic Dissection
We are undertaking investigations of the pathophysiology of aortic dissection utilizing computational tomographic angiography (CTA), 3D modeling, numerical stress or finite element analysis (FEA), and computational fluid dynamics (CFD). The aim of these studies will be to better understand and develop novel management strategies for aortic dissections.
Novel Image Analysis for Predicting Aneurysm Growth
Using morphometric analysis and nonrigid registration of sequential CTA studies in patients, we strive to objectively measure the regional growth in the aortic wall over time, and to correlate the local aortic wall expansion to accepted indices of rupture risk.
Mechanical Modeling of Thoracoabdominal Aortic Aneurysms
The risk of thoracoabdominal aortic aneurysm (TAAA) rupture is poorly understood; and the risk of repair is considerable. Therefore, in silica engineering analyses (utilizing FEA) to predict rupture risk are more compelling and needed than for simple abdominal aortic aneurysms (AAAs).