In collaboration with the Emory
Center for Cancer Nanotechnology Excellence, Dr. Sunil
Singhal is working closely with Dr.
Shuming Nie to develop the next generation of intra-operative
imaging techniques. With the help of our collaborators, we are aggressively
pursuing multiple techniques and
approaches to Intraoperative Imaging in the hopes of giving patients
more complete resections of primary, micrometastatic, and lymphatic
disease while minimizing unnecessary tissue reductions and shortening
hospital stays. As part of the bench-to bedside-to bench approach,
we are heavily invested in both in both human and animal studies
to optimize our procedures.
Currently, our focus in intraoperative imaging is two-fold. Through
our clinical arm, patients will be enrolled in our clinical trial
in the hopes of identifying local and distal metastases with the
use of our collaborator’s newly
developed software, imaging system and commonly administered non-radioactive
isotopes. Through the excitation of molecules in non-toxic chemicals,
the malignancies previously undetectable to the surgeon in the operating
room will no longer pose a threat to patient health.
Secondly, our mouse modeling systems are examining multiple modalities
of nanotechnology, utilizing reagents at the forefront of surgical
imaging technology; the quantum dot. The mice we’re working
with are furthering the cause of medical advancement through improving
the safety and efficacy of these approaches.