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Thomas J. Guzzo, MD, MPH
Urology

 
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  • Societies
  • Research
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Administrative/Clinical Offices:
Perelman Center for Advanced Medicine
West Pavilion, 3rd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Administrative Assistant: Siobhan Harris
Administrative Telephone: 215-662-2891
Administrative Fax: 215-662-3955

Contact Information (internal use only)

thomas.guzzo@uphs.upenn.edu

 

Dr. Guzzo is an Associate Professor of Urology and is the Chief of the Division of Urology. He is a graduate of Temple University School of Medicine. He completed his general surgery internship and urology residency at the Hospital of the University of Pennsylvania. Dr. Guzzo completed a two year fellowship at the James Buchanan Brady Urological Institute of the Johns Hopkins Hospital in urologic oncology. During his fellowship he also earned a Masters in Public Health from the Johns Hopkins Bloomberg School of Public Health. He is extensively trained in the treatment of all aspects of urologic malignancies including open, laparoscopic, endoscopic and robotic surgical treatment for such malignancies.

Dr. Guzzo’s clinical areas of expertise include the surgical treatment of prostate, bladder, kidney and testicular cancer. There are many options for patients with urologic cancer and because Dr. Guzzo’s expertise includes open, endoscopic, laparoscopic and robotic surgery he is equipped to individualize treatment options for patients with a wide range of urologic malignancies. Additionally, Dr. Guzzo is a collaborator with the proton therapy program at the University of Pennsylvania.

Dr. Guzzo is a member of the American Urologic Association and the American College of Surgeons. He is actively involved in urologic research having published over 40 peer-reviewed manuscripts and five book chapters. Additionally, he has presented multiple clinical research abstracts at both national and international meetings. He was the recipient of the prestigious Prostate Cancer Foundation Young Investigator Award in 2009. Dr. Guzzo’s areas of research interest include patient reported outcomes and quality of life after urologic cancer surgery.

 
Faculty Appointments
2015 - present  Associate Professor of Urology and Surgery
Perelman School of Medicine, University of Pennsylvania
Philadelphia, Pennsylvania
 
2009 - 2015 Assistant Professor of Urology and Surgery
Perelman School of Medicine, University of Pennsylvania
Philadelphia, Pennsylvania
 
2007 - 2009  Clinical Instructor in Urology
James Buchanan Brady Urological Institute of Johns Hopkins University
Baltimore, Maryland
 
Hospital and Administrative Appointments
2017 - present Chief of Urology
Hospital of the University of Pennsylvania
 
2013 - present  Committee Member, Chief of Abdominal Imaging Search Committee
 
2013 - present  Co-chair, GU Oncology Leadership Committee
 
2013 - present  Chair, Clinical Competency Committee, Urology
 
2012 - present Committee Member, HUP Robotic Surgery Committee
 
2012 - present Vice-Chief, Division of Urology
 
2012 - present  Co-Chair, HUP GU Tumor Board
 
2011 - present  Committee Member, Medical Legal Committee, HUP
 
2011 - present Associate Director of the Residency Program in Urology
 
2009 - present  Grand Rounds Coordinator, Division of Urology
 
2009 - present  Course Director, Urology Medical Student 345 Rotation
 
2009 - present   Course Director, Urology Medical Student 200 Rotation
 
Education/Training
2007 - 2009 MPH - Johns Hopkins Bloomberg School of Public Health
Baltimore, Maryland
 
1998 - 2002 MD - Temple University School of Medicine
Philadelphia, Pennsylvania
 
1997 - 1998 Post-Baccalaureate/Pre-Medical Program
Duquesne University
Pittsburgh, Pennsylvania
 
1993 - 1997 BS - Ursinus College (Biology)
Collegeville, Pennsylvania
 
Postgraduate Training and Fellowship Appointments
2002 - 2003 Intern in General Surgery
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
   
2003 - 2007 Resident in Urology
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
   
2007 - 2009 Fellow in Urologic Oncology
James Buchanan Brady Urological Institute of Johns Hopkins University
Baltimore, Maryland
 
Memberships/Societies
National/International Societies
2012 - present Bladder Cancer Advocacy Network
 
2008 - present Prostate Cancer Foundation (Scientific Advisory Board)
 
2007 - present American Urologic Association
 
2003 - present American College of Surgeons
 
2002 - present American Medical Association
 
Local/Regional Societies
2007 - present Philadelphia Urologic Society
(Member, Executive Committee, 2010-present)
 
2007 - present Mid-Atlantic Section, American Urologic Association
 
Research

Clinical Trials

04/01/2015 - 03/31/2019 Understanding Disparity in Quality of Cancer Care
 
07/01/2014 - 06/30/2018 Factors Associated with Variation in Quality of Prostate Cancer Care
 
06/01/2014 - 05/31/2017 Co-registering Pathology with PET and MRI to Identify Fused Imaging Features for Clinically Significant Prostate Cancer
 
02/18/2014 - 02/19/2019 UPCC 19812: A Pilot and Feasibility Study of the Imaging Potential of EC17 in Subjects Under-going Surgery Presenting with Renal Masses
 
09/01/2013 - 08/31/2018 Intraoperative Imaging of Folate Receptor Alpha Positive Tumors with EC17
 
07/01/2013 - 06/30/2016 Treatment Preferences and Patient Centered Prostate Cancer Care
 
07/01/2013 - 06/30/2015 Patient Centered Overactive Bladder Care
 
01/01/2013 - 12/31/2018 UPCC 13812: Phase III Randomized Trial of Proton Therapy vs. IMRT for Low or  Low-Intermediate Risk Prostate Cancer
 
05/05/2011 - 04/30/2016 A Feasibility Trial of Proton Radiation Therapy Using Mild Hypofractionation for Intermediate Risk Prostate Cancer
 
09/01/2012 - 08/31/2014 AHRQ Evidence based Practice Centers (EPCs) IV
 
06/14/2012 - 09/14/2012 N/A - A Phase 3b, Randomized, Open-Label, Multi-Center Study To Evaluate The Efficacy And Safety Of Maintenance Therapy With Valrubicin Versus No Maintenance, In Subjects Treated With Valrubicin Induction For Carcinoma In Situ (Cis) Of The Bladder
 
01/25/2012 - 04/30/2014 UPCC 19811: Phase I/II Trial of Adjuvant Radiation Therapy for the Treatment of Urothelial Bladder Cancer Using Proton Therapy or IMRT
 
07/01/2011 - 06/30/2013 A Phase II study of Adjuvant Proton Radiation Therapy for the Treatment of Stage I, IIA, and IIB Seminoma
 
05/01/2011 - 12/31/2012 Correlation of Peripheral Vein Tumor Marker Levels, Internal Iliac Vein Tumor Marker Levels, and Radical Prostatectomy Specimens in Patients with Prostate Cancer
 
10/01/2009 - 12/30/2010 Out of Pocket Expenses and Treatment Choice for Men with Prostate Cancer: Preparing for a Randomized Trial
 
07/01/2008 - 06/30/2011 Young Investigator Award
 
Publications
Research Publications, Peer Reviewed
  1. Guzzo, Thomas.  Gerstein, Matthew.  Mydlo, Jack H.: Granulosa cell tumor of the contralateral testis in a man with a history of cryptorchism. Urologia Internationalis 72(1): 85-7, 2004.
  2. Guzzo, Thomas J.  Vira, Manish.  Hwang, Wei-Ting.  D'amico, Anthony.  Tomaszewski, John.  Whittington, Richard.  Wein, Alan J.  Vanarsdalen, Keith.  Malkowicz, S Bruce.: Impact of multiple biopsy cores on predicting final tumor volume in prostate cancer detected by a single microscopic focus of cancer on biopsy. Urology 66(2): 361-5, Aug 2005.
  3. Zuniga, Zachary V.  Guzzo, Thomas.  Docimo, Steven G.: Bilateral single system ectopic ureters in a male infant. Urology 66(2): 432, Aug 2005.
  4. Guzzo, Thomas J.  Vira, Manish.  Wang, Yanlin.  Tomaszewski, John.  D'amico, Anthony.  Wein, Alan J.  Malkowicz, S Bruce.: Preoperative parameters, including percent positive biopsy, in predicting seminal vesicle involvement in patients with prostate cancer. Journal of Urology 175(2): 518-21; discussion 521-2, Feb 2006.
  5. Kutikov, Alexander.  Guzzo, Thomas J.  Canter, Daniel J.  Casale, Pasquale.: Initial experience with laparoscopic transvesical ureteral reimplantation at the Children''s Hospital of Philadelphia. Journal of Urology 176(5): 2222-5; discussion 2225-6, Nov 2006.
  6. Kutikov, Alexander.  Nguyen, Michael.  Guzzo, Thomas.  Canter, Daniel.  Casale, Pasquale.: Robot assisted pyeloplasty in the infant-lessons learned. Journal of Urology 176(5): 2237-9; discussion 2239-40, Nov 2006.
  7. Guzzo, Thomas J.  Vira, Manish A.  Neway, William.  Hwang, Wei-Ting.  Tomaszewski, John.  VanArsdalen, Keith.  Wein, Alan J.  Malkowicz, S Bruce.: Minimal tumor volume may provide additional prognostic information in good performance patients after radical prostatectomy. Urology 69(6): 1147-51, Jun 2007.
  8. Kutikov, Alexander.  Nguyen, Michael.  Guzzo, Thomas.  Canter, Daniel.  Casale, Pasquale.: Laparoscopic and robotic complex upper-tract reconstruction in children with a duplex collecting system. Journal of Endourology 21(6): 621-4, Jun 2007.
  9. Guzzo, Thomas J.  Levin, Brian M.  Lee, Richard.  Guo, Mengye.  Chen, Zhen.  Whittington, Richard.  Tomaszewski, John.  Malkowicz, S Bruce.: Relationship of biochemical outcome to percentage of positive biopsies in men with clinically localized prostate cancer treated with permanent interstitial brachytherapy. Urology 71(4): 723-7, Apr 2008.
  10. Vira, Manish A.  Guzzo, Thomas.  Heitjan, Daniel F.  Tomaszewski, John E.  D'Amico, Anthony.  Wein, Alan J.  Malkowicz, S Bruce.: Is the biopsy Gleason score important in predicting outcomes for patients after radical prostatectomy once the pathological Gleason score is known? BJU International 101(10): 1232-6, May 2008.
  11. Resnick, Matthew J.  Canter, Daniel.  Brucker, Benjamin M.  Kutikov, Alexander.  Guzzo, Thomas J.  Wein, Alan J.  Medscape.: A case of synchronous bilateral testicular seminoma. Nature Clinical Practice Urology 5(7): 397-401, Jul 2008.
  12. Canter, Daniel.  Guzzo, Thomas J.  Resnick, Matthew J.  Brucker, Benjamin.  Vira, Manish.  Chen, Zhen.  Tomaszewski, John.  VanArsdalen, Keith.  Wein, Alan J.  Malkowicz, S Bruce.: Hydronephrosis is an independent predictor of poor clinical outcome in patients treated for muscle-invasive transitional cell carcinoma with radical cystectomy. Urology 72(2): 379-83, Aug 2008.
  13. Guzzo, Thomas J.  Kutikov, Alexander.  Canter, Daniel J.  Tomaszewski, John E.  Magerfleish, Laurie.  VanArsdalen, Keith.  Wein, Alan J.  Malkowicz, S Bruce.: The clinical and pathological history of prostate cancer progression in men with a prior history of high grade prostatic intraepithelial neoplasia. Canadian Journal of Urology 15(4): 4174-8; discussion 4179, Aug 2008.
  14. Canter, Daniel.  Guzzo, Thomas.  Resnick, Matthew.  Magerfleisch, Laurie.  Sonnad, Seema.  Bergey, Meredith.  Tomazewski, John.  Vaughn, David.  Van Arsdalen, Keith.  Malkowicz, Bruce.: The presence of lymphovascular invasion in radical cystectomy specimens from patients with urothelial carcinoma portends a poor clinical prognosis. BJU International 102(8): 952-7, Sep 2008.
  15. Kutikov, Alexander.  Vanarsdalen, Keith N.  Gershman, Boris.  Fossett, Lindsay K.  Guzzo, Thomas J.  Wein, Alan J.  Malkowicz, S Bruce.: Enucleation of renal cell carcinoma with ablation of the tumour base. BJU International 102(6): 688-91, Sep 2008.
  16. Guzzo, Thomas J.  Schaeffer, Edward M.  Allaf, Mohamad E.: Laparoscopic radical nephroureterectomy with en-bloc distal ureteral and bladder cuff excision using a single position pneumovesicum method. Urology 72(4): 850-2, Oct 2008.
  17. Bivalacqua, Trinity J.  Guzzo, Thomas J.  Schaeffer, Edward M.  Gebska, Milena A.  Champion, Hunter C.  Burnett, Arthur L.  Gonzalgo, Mark L.: Application of Evicel to cavernous nerves of the rat does not influence erectile function in vivo. Urology 72(5): 1169-73, Nov 2008.
  18. Guzzo, Thomas J.  Rogers, Craig G.  Deng, Chris Y.  Bivalacqua, Trinity J.  Palapattu, Ganesh S.  Bastian, Patrick J.  Eisenberger, Mario A.  Schoenberg, Mark P.  Gonzalgo, Mark L.: Outcomes of patients after aborted radical cystectomy for intraoperative findings of metastatic disease. BJU International 102(11): 1539-43, Dec 2008.
  19. Guzzo, Thomas J.  Schaeffer, Edward M.  McNeil, Brian K.  Pollock, Richard A.  Pavlovich, Christian P.  Allaf, Mohamad E.: Laparoscopic radical nephrectomy for patients with pathologic T3b renal-cell carcinoma: the Johns Hopkins experience. Journal of Endourology 23(1): 63-7, Jan 2009.
  20. Bivalacqua, Trinity J.  Bagga, Herman S.  Patil, Kaustubha.  Magheli, Ahmed.  Taube, Janis M.  Guzzo, Thomas J.  Gonzalgo, Mark L.: Urethral carcinosarcoma from bladder carcinosarcomatous lesions: analysis of clinicopathological features. Canadian Journal of Urology 16(1): 4512-5, Feb 2009.
  21. Guzzo, Thomas J.  Pierorazio, Phillip M.  Schaeffer, Edward M.  Fishman, Elliot K.  Allaf, Mohamad E.: The accuracy of multidetector computerized tomography for evaluating tumor thrombus in patients with renal cell carcinoma. Journal of Urology 181(2): 486-90; discussion 491, Feb 2009.
  22. Guzzo, Thomas J.  Pollock, Richard A.  Forney, Allen.  Aggarwal, Piyush.  Matlaga, Brian R.  Allaf, Mohamad E.: Safety and efficacy of a surgeon-prepared gelatin hemostatic agent compared with FloSeal for hemostasis in laparoscopic partial nephrectomy. Journal of Endourology 23(2): 279-82, Feb 2009.
  23. Guzzo, Thomas J.  Allaf, Mohamad E.  Pierorazio, Phillip M.  Miller, Daniel.  McNeil, Brian K.  Kavoussi, Louis R.  Pavlovich, Christian P.  Schaeffer, Edward M.: Perioperative outcomes of elderly patients undergoing laparoscopic renal procedures. Urology 73(3): 572-6, Mar 2009.
  24. Resnick, M J.  Canter, D J.  Guzzo, T J.  Brucker, B M.  Bergey, M.  Sonnad, S S.  Wein, A J.  Malkowicz, S B.: Does race affect postoperative outcomes in patients with low-risk prostate cancer who undergo radical prostatectomy? Urology 73(3): 620-3, Mar 2009.
  25. Pietzak EJ, Guzzo TJ.: Advancements in laparoscopic partial nephrectomy: Expanding the feasibility of nephron-sparing.  Advances in Urology  May 2009.
  26. Rais-Bahrami S, Guzzo TJ, Jarrett TW, Kavoussi LR, Allaf ME: Incidentally discovered renal masses: Oncologic and perioperative outcomes in patients with delayed surgical intervention. [In press] BJU International  May 2009.
  27. Canter D, Guzzo TJ, Resnick MJ, Bergey MR, Sonnad SS, Tomaszewski J, Van Arsdalen K, Malkowicz SB.: A thorough pelvic lymph node dissection in presence of positive margins associ-ated with better clinical outcomes in radical cystectomy patients. Urology  74(1): 161-165, July 2009.
  28. Guzzo TJ, Bivalacqua TJ, Pierorazio PM, Varkarakis J, Schaeffer EM, Allaf ME: Xanthogranulomatous pyelonephritis: Presentation and management in the laparoscopic era.  British Journal of Urology  104(9): 1265-1268, Nov 2009.
  29. Alphs HH, Miles-Thomas J, Attenello F, Taube JM, Fonseca G, Guzzo TJ: Presentation and management of a patient with subcutaneous metastatic transitional cell carcinoma of the bladder. [In press] Nature Clinical Practice Urology  2009.
  30. Guzzo TJ, Allaf ME: Laparoscopic retroperitoneal lymph node dissection for stage I and II nonseminomatous germ-cell tumors. [In press] Therapeutic Advanced Urology  2009.
  31. Guzzo TJ, Gonzalgo ML: Robotic surgical training of the urologic oncologist. [In press] Seminars in Urologic Oncology  2009.
  32. Guzzo TJ, Magheli A, Bivalacqua TJ, Nielsen ME, Attenello FJ, Schoenberg MP, Gonzalgo ML.: Pathologic upstaging at the time of radical cystectomy is associated with worse recurrence free survival in patients with BCG-refractory bladder cancer. Urology  74(6): 1276-1280, Dec 2009.
  33. Mayer WA, Canter DJ, Resnick M, Kutikov A, Carpiniello VL, Ramchandani P, Harryhill JF, Guzzo TJ: Synchronous metastatic renal cell carcinoma to the genitourinary tract: Two rare case reports and review of the literature. [In press] Canadian Journal of Urology  2009.
  34. Resnick MJ, Canter DJ, Guzzo TJ, Magerfleisch L, Tomaszewski JE, Brucker BM, Bergey MR, Sonnad SS, Wein AJ, Malkowicz SB.: Defining pathological variables to predict bio-chemical failure in patients with positive surgical margins at radical prostatectomy: implications for adjuvant radiotherapy. BJU International  105(10): 1377-1380, May 2010.
  35. Pollock R, Mozer P, Guzzo TJ, Mark J, Matlaga B, Petrisor D, Vigaru B, Badaan S, Stoianovici D, Allaf ME.: Future prospects in percutaneous ablative targeting: Comparison of a computer-assisted navigation system and "AcuBot" robotic system. Journal of Endourology  24(8): 1269-1272, Aug 2010.
  36. Guzzo TJ, Dluzniewski P, Orosco R, Platz EA, Partin AW, Han M.: Prediction of mortality following radical prostatectomy by Charlson comorbidity index.   Urology 76(3): 553-557, Sept 2010.
  37. Pierorazio PM, Guzzo TJ, Han M, Bivalacqua TJ, Epstein JI, Schaeffer EM, Schoenberg MP, Walsh PC, Partin AW.: Long-term survival after radical prostatectomy for men with high Gleason sum in the pathological specimen.  Urology 76(3): 715-721, Sept 2010.
  38. Bivalacqua TJ, Loeb S, Pierorazio PM, Schoenberg MP, Partin AW, Guzzo TJ.: Is prostate specific antigen surveillance necessary in men with benign prostate pathology following radical cystoprostatectomy for bladder cancer?  Urologia Internationalis  85(4): 466-469, Nov 2010.
  39. Guzzo TJ, Gonzalgo ML, Allaf ME.: Laparoscopic retroperitoneal lymph node dissection with therapeutic intent in men with clinical stage I nonseminomatous germ cell tumors.  Journal of Endourology  24(11): 1759-1763, Nov 2010.
  40. Guzzo TJ, Resnick MJ, Canter DJ, Balandra A, Bergey MR, Magerfleish L, Tomaszewski JE, Vaughn DJ, Malkowicz SB.: Impact of adjuvant chemotherapy on patients with lymph node metastasis at the time of radical cystectomy.  Canadian Journal of Urology  17(6): 5465-5471, Dec 2010.
  41. Han M, Trock BJ, Partin AW, Humphreys EB, Bivalacqua TJ, Guzzo TJ, Walsh PC.: The impact of preoperative erectile dysfunction on survival after radical prostatectomy.  BJU International  106(11): 1612-1617, Dec 2010.
  42. Resnick, MJ, Bergey M, Magerfleisch L, Tomaszewski JE, Malkowicz SB, Guzzo TJ.: Longitudinal evaluation of the concordance and prognostic value of lymphovascular invasion in transurethral resection and radical cystectomy. BJU International  107(1): 46-52, Jan 2011.
  43. Resnick MJ, Lee DJ, Van Arsdalen K, Wein AJ, Tomaszewski JE, Malkowicz SB, Guzzo TJ.: Repeat prostate biopsy and the incremental risk of clinically insignificant prostate cancer. Urology 77(3): 548-552, Mar 2011.
  44. Magheli A, Gonzalgo ML, Su LM, Guzzo TJ, Netto G, Humphreys EB, Han M, Partin AW, Pavlovich CP.: Impact of surgical technique (open vs laparoscopic vs robotic-assisted) on patho-logical and biochemical outcomes following radical prostatectomy: An analysis using propensity score matching.  BJU International 107(12): 1956-1962, June 2011.
  45. Resnick MJ, Guzzo TJ: Patient selection essential in optimizing the benefit of radical prostatectomy for patients with organ-confined prostate cancer.   Asian Journal of Andrology  13(6): 789-790, Nov 2011.
  46. Yeboa DN, Guzzo TJ, Mitra N, Christodouleas JP, Haas NB, Vapiwala N, Armstrong K, Bekelman JE.: Prostate specific antigen surveillance among men with clinically localized prostate cancer who do not receive initial treatment.  Urology 78(5): 1107-1113, Nov 2011.
  47. Guzzo TJ, Hockenberry BA, Mucksavage P, Bivalacqua TJ, Schoenberg MP.: Smoking knowledge assessment and cessation trends in patients with bladder cancer.  Urology  79(1): 166-171, Jan 2012.
  48. Mucksavage P, Ramchandani P, Malkowicz SB, Guzzo TJ.  : Is ultrasound imaging inferior to computed tomography or magnetic resonance imaging in evaluating renal mass size?  Urology 79(1): 28-31, Jan 2012.
  49. Wehrenberg-Klee E, Clark TW, Malkowicz SB, Soulen MC, Wein AJ, Mondschein JI, Van Arsdalen KV, Guzzo TJ, Stavropoulos SW: Impact on renal function of percutaneous thermal ablation of renal masses in patients with preexisting chronic kidney disease.  Journal of Vascular & Interventional Radiology  23(1): 41-45, Jan 2012.
  50. Guzzo TJ, Resnick MJ, Canter DJ, Bivalacqua TJ, Rosen MA, Bergey MR, Magerfleisch L, Tomaszewski JE, Wein AJ, Malkowicz SB.: Endorectal T2-weighted MRI does not differen-tiate between favorable and adverse pathologic features in men with prostate cancer who would qualify for active surveillance. Urologic Oncology  30(3): 301-305, May-June 2012.
  51. Swisher-McClure S, Pollack CE, Christodouleas JP, Guzzo TJ, Haas NB, Vapiwala N, Bekelman JE.: Variation in us of androgen suppression with external-beam radiotherapy for nonmetastatic prostate cancer. International Journal of Radiation Oncology, Biology & Physics 83(1): 8-15, May 2012.
  52. Wang H, Albadine R, Magheli A, Guzzo TJ, Ball MW, Hinz S, Schoenberg MP, Netto GJ, Gonzalgo ML.: Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder.   Urologic Oncology  30(4): 428-433, July-Aug 2012.
  53. Jang JW, Hwang WT, Guzzo TJ, Wein AJ, Haas NB, Both S, Vapiwala N.: Upfront androgen deprivation therapy with salvage radiation may improve biochemical outcomes in prostate cancer patients with post-prostatectomy rising PSA.   nternational Journal of Radiation Oncology, Biology & Physics  83(5): 1493-1499, Aug 2012.
  54. Nielsen ME, Smith AB, Pruthi RS, Guzzo TJ, Amiel G, Shore N, Lotan Y.: Reported use of intravesical therapy for non-muscle-invasive bladder cancer (NMI13C): Results from the Bladder Cancer Advocacy Network (BeAN) survey.  BJU International  110(7): 967-972, Oct 2012.
  55. Jung OS, Guzzo TJ, Lee D, Mehler M, Christodouleas J, Deville C, Hollis G, Shah A, Vapiwala N, Wein AJ, Pauly M, Bekelman JE. : Out-of pocket expenses and treatment choice for men with prostate cancer.  Urology 80(6): 1252-1257, Dec 2012.
  56. Mullins JK, Guzzo TJ, Ball MW, Pierorazio PM, Eifler J, Jarrett TW, Schoenberg MP, Bivalacqua TJ.: Ureteral stents placed at the time of urinary diversion decreases postoperative morbidity.  Urologia Internationalis  88(1): 66-70, 2012.
  57. Baumann BC, Guzzo TJ, He J, Keefe SM, Tucker K, Bekelman JE, Hwang WE, Vaughn DJ, Malkowicz SB, Christodouleas JP.: A novel risk stratification to predict local-regional failures in urothelial carcinoma of the bladder after radical cystectomy.  International Journal of Radiation Oncology 85(1): 81-88, Jan 2013.
  58. Baumann BC, Guzzo TJ, He J, Vaughn OJ, Keefe SM, Vapiwala N, Deville C, Bekelman JE, Tucker K, Hwang WT, Malkowicz SB, Christodouleas JP.: Bladder cancer patterns of pelvic failure: Implications for adjuvant radiation therapy.  International Journal of Radiation Oncology Biology & Physics 85(2): 363-369, Feb 2013.
  59. Resnick MJ, Guzzo TJ, Cowan JE, Knight SJ, Carroll PR, Penson OF.: Factors associated with prostate cancer care: Results from the Cancer of the Prostate Strategic Urologic Research Endeavor (CaPSURE).  BJU International  111(2): 213-220, Feb 2013.
  60. Goldsmith B, Tucker K, Conway RG, He J, Guzzo TJ, Bekelman JE, Deville C, Vapiwala N, Malkowicz SB, Christodouleas J.: Discordance between preoperative and postoperative bladder cancer location: Implications for partial-bladder radiation. International Journal of Radiation Oncology Biology & Physics  85(3): 707-713, Mar 2013.
  61. Truesdale CM, Soulen MC, Clark TW, Mondschein JI, Wehrenberg KE, Malkowicz SB, Wein AJ, Guzzo TJ, Stavropoulos SW.: Percutaneous computed tomography-guided renal mass radiofrequency ablation vs. cryoablation: Doses of sedation medication used.   Journal of Vascular & Interventional Radiology  24(3): 347-350, Mar 2013.
  62. Bekelman JE, Handorf EA, Guzzo TJ, Christodouleas J, Resnick MJ, Swisher-McClure S, Vaughn D, Polsky D, Mitra N.: Radical cystectomy vs. bladder-preserving therapy for muscle-invasive urothelial carcinoma: Examining confounding and misclassification bias in cancer observational comparative effectiveness research.  Value Health  16(4): 610-618, June 2013.
  63. Bekelman JE, Suneja G, Guzzo TJ, Pollack CE, Armstrong K, Epstein AJ.: Effect of practice integration between urologists and radiation oncologists on prostate cancer treatment patterns.  Journal of Urology  190(1): 97-101, July 2013.
  64. Smith ZL, Guzzo TJ.: Urinary markers for bladder cancer. F1000 Prime Reports  5, July 2013.
  65. Lotan Y, Amiel G, Boorjian SA, Clark PE, Droller M, Gingrich JR, Guzzo TJ, Inman BA, Kamat AM, Karsh L, Nielsen ME, Smith ND, Shariat SF, Svatek RS, Taylor JM.: Comprehensive handbook for developing a bladder cancer cystectomy database. Urologic Oncology 31(6): 812-826, Aug 2013.
  66. Weiss BE, Wein AJ, Malkowicz SB, Guzzo TJ.: Comparison of prostate volume measured by transrectal ultrasound and magnetic resonance imaging: Is transrectal ultrasound suitable to determine which patients should undergo active surveillance?  Urologic Oncology  31(8): 1436-1440, Nov 2013.
  67. Raman JD, Lin YK, Kaag M, Atkinson T, Crispen P, Wille M, Smith N, Hockenberry M, Guzzo T, Peyronnet B, Bensalah K, Simhan J, Kutikov A, Cha E, Herman M, Scherr D, Shariat SF, Boorjian SA. : High rates of advanced disease, complications, and decline of renal function after radical nephroureterectomy.   Urologic Oncology  32(1): e9-14, Jan 2014.
  68. Canter DJ, Revenig LM, Smith ZL, Dobbs RW, Malkowicz SB, Issa MM, Guzzo TJ.: Re-examination of the natural history of high-grade T1 bladder cancer using a large contemporary cohort.  International Brazilian Journal of Urology  40(2): 172-178, Mar-Apr 2014.
  69. Goldsmith B, Baumann BC, He J, Tucker K, Bekelman J, Deville C, Vapiwala N, Vaughn D, Keefe SM, Guzzo TJ, Malkowicz SB, Christodouleas JP.: Occult pelvic lymph node involvement in bladder cancer: implications for definitive radiation.  International Journal of Radiation Oncology Biology & Physics  88(3): 603-610, Mar 2014.
  70. Ju M, Kao GD, Steinmetz D, Chandrasekaran S, Keefe SM, Guzzo TJ, Christodouleas JP, Hahn SM, Dorsey JF.: Application of a telomerase-based circulating tumor cell (CTC) assay in bladder cancer patients receiving postoperative radiation therapy: A case study.   Cancer Biology & Therapy  15(6): 683-687, June 2014.
  71. Lei Q, Pan XQ, Chang S, Malkowicz SB, Guzzo TJ, Malykhina AP.: Response of the human detrusor to stretch is regulated by TREK-1, a two-pore-domain (K2P) mechano-gated potassium channel.   Journal of Physiology  592(Pt 14): 3013-3030, July 2014.
  72. Ziemba JB, Golan R, Skokan A, Patel D, Feldman MD, Bing Z, Guzzo TJ.: The clinical presentation and outcome of urothelial atypia on biopsy of the bladder. Urological Oncology  32(5): 645-647, July 2014.
  73. Pietzak EJ, Resnick MJ, Mucksavage P, Van Arsdalen K, Wein AJ, Malkowicz SB, Guzzo TJ.: Multiple repeat prostate biopsies and the detection of clinically insignificant cancer in men with large prostates.  Urology  84(2): 380-385, Aug 2014.
  74. Newman DK, Guzzo T, Lee D, Jayadevappa R.: An evidence-based strategy for the conservative management of the male patient with incontinence.   Current Opinion in Urology  24(6): 553-559, Nov 2014.
  75. Pietzak EJ, Hwang WT, Malkowicz SB and Guzzo TJ.: Factors influencing the length of stay after radical cystectomy: implications for cancer care and perioperative management.  Annals of Surgical Oncology  21(13): 4383-4389, Dec 2014.
  76. Pietzak EJ, Kabarriti AE, Mucksavage P, Bavaria T, Van Arsdalen K, Malkowicz SB, Wein AJ and Guzzo T.: The presence of high-grade prostatic intraepithelial neoplasia of atypia on prostate biopsy does not adversely affect prostatectomy outcomes for patients otherwise eligible for active surveillance.  Urology  84(6): 1442-1447, Dec 2014.
  77. Graves R, Laryngakis N, Malkowicz SB, Guzzo TJ.: Therapeutic options for men with castrate-resistant prostate cancer.  Annals of Urology  2015 (In press)
  78. Pietzak EJ, Van Arsdalen K, Patel K, Malkowicz SB, Wein AJ and Guzzo TJ.: Impact of race on selecting appropriate patients for active surveillance with seemingly low-risk prostate cancer.  Urology 85(2): 436-440, Feb 2015.
  79. Christodouleas JP, Baumann BC, He J, Hwang WT, Tucker KN, Bekelman JE, Tangen CM, Lerner SP, Guzzo TJ, Malkowicz SB. : Optimizing bladder cancer locoregional failure risk stratification after radical cystectomy using SWOG 8710.   Cancer. 120(8): 1272-1280, Apr 2015.
  80. Fang P, Mick R, Deville C, Both S, Bekelman JE, Christodoleas JP, Guzzo TJ, Tochner Z, Hahn SM, Vapiwala N. : A case-matched study of toxicity outcomes after proton therapy and intensity-modulated radiation therapy for prostate cancer.   Cancer  121(7): 1118-1127, Apr 2015.
  81. Pietzak EJ, Sterling ME, Smith ZL, Malkowicz SB, Guzzo TJ. : Outcomes of radical cystectomy in potential candidates for bladder preservation therapy.   Urology  85(4): 869-875, Apr 2015.
Research Publications, peer-reviewed reviews
  1. Zuniga ZV, Guzzo T, Docimo SG.  : Bilateral single system ectopic ureters in a male infant. [Case Report] Urology  66(2): 432, Aug 2005.
  2. Kutikov, Alexander.  Guzzo, Thomas J.  Malkowicz, S Bruce.: Clinical approach to the prostate: an update. [Review]  Radiologic Clinics of North America 44(5): 649-63, vii, Sep 2006.
  3. Kasturi, Sanjay.  Kutikov, Alexander.  Guzzo, Thomas J.  Smith, Ariana L.  Wein, Alan J.: Modern management of pheochromocytoma. [Review]  Nature Clinical Practice Urology 4(11): 630-3, Nov 2007 Notes: Erratum appears in Nat Clin Pract Urol. 2007 Dec; 4(12):692.
  4. Guzzo, Thomas J.  Bivalacqua, Trinity J.  Schoenberg, Mark P.: Bladder cancer and the aluminium industry: a review. [Review]  BJU International 102(9): 1058-60, Nov 2008.
  5. Guzzo TJ, Allaf ME.: Laparoscopic retroperitoneal lymph node dissection for stage I and II non-seminomatous germ-cell tumors. [Review] Therapeutic Advances in Urology  1(2): 107-114, Jun 2009.
  6. Graves R, Laryngakis N, Malkowicz SB, Guzzo TJ.: Therapeutic options for men with castrate-resistant prostate cancer. [Review]  Annals of Urology 1(1), July 2010 Notes: (Online Resource).
  7. Sehgal SS, Wein AJ, Malkowicz SB, Guzzo TJ.: Neuroendocrine tumor of the bladder: A case report and review of the literature. [Review] Reviews in Urology  12(4): e197-201, Fall 2010.
  8. Guzzo TJ, Drach GW.  : Major urologic problems in geriatrics: Assessment and management. [Review]  Medical Clinics of North America  95(1): 253-64, Jan 2011.
  9. Resnick MJ, Guzzo TJ.: Bladder cancer: Improvements in clinical staging of muscle-invasive bladder cancer. [Review]  Nature Reviews Urology  8(7): 360-361, May 2011.
  10. Laryngakis NA, Van Arsdalen KN, Guzzo TJ, Malkowicz SB.  : Tumor enucleation: A safe alternative for renal cell carcinoma. [Review]  Expert Reviews in Anticancer Therapy  11(6): 893-899, Jun 2011.
  11. Laryngakis NA, Guzzo TJ.: Tumor enucleation for small renal masses. [Review]  Current Opinion in Urology  22(5): 365-371, Sept 2012.
  12. Meng X, Guzzo TJ, Bing Z.  : Malignant mesotheliomas in spermatic cords: Reports of two cases and a brief review of literature. [Review]  Rare Tumors  5(1): e4, Mar 2013.
  13. Guzzo TJ.: Small renal masses: The promise of thulium laser enucleation partial nephrectomy. [Review]  Nature Reviews: Urology  10(5): 259-260, May 2013.
  14. Smith ZL, Christodouleas JP, Keefe SM, Malkowicz SB, Guzzo TJ.: Bladder preservation in the treatment of muscle-invasive bladder cancer (MIBC): E review of the literature and practical approach to therapy. [Review]  BJU International  112(1): 13-25, July 2013.
  15. Kathrins M, Caesar S, Mucksavage P, Guzzo TJ. : Renal mass size: Concordance between pathology and radiology. [Review]  Current Opinion in Urology  3(5): 389-393, Sept 2013.
  16. Kabarriti A, Pietzak EJ, Canter DJ, Guzzo TJ.: The relationship between age and perioperative complications. [Review] Current Geriatric Reports  3: 8-13, Jan 2014.
  17. Revenig LM, Ogan K, Guzzo TJ, Canter DJ.: The use of frailty as a surgical risk assessment tool in elderly patients. [Review]  Current Geriatric Reports  3: 1-7, Jan 2014.
Editorials, Reviews, Chapters, including participation in committee reports (print or other media)
  1. Guzzo T, Gerstein M. Mydlo JH: Granulosa cell tumor of the contralateral testis in a man with a history of cryptorchism. [Case Report]  Urologia Internationalis  72(7): 85-87, 2004.
  2. Guzzo TJ, Malkowicz SB: Retroperitoneal diseases.   Penn Clinical Manual of Urology. Hanno PM, Wein AJ, Malkowicz SB (eds.). Philadelphia: Elsevier, Page: 653-64, 2007 Notes: Chap. 18.
  3. Guzzo TJ, Vira MA, Dey W, Hwang WT, Tomaszewski J, Van Arsdalen K, Wein AJ, Malkowicz B: Minimal tumor volume may provide additional prognostic information in good performance patients after radical prostatectomy. Urology 69: 1147-1151, 2007. [Commentary]  Urology  71(6): 1230-1231, Jun 2008.
  4. Resnick MJ, Canter D, Brucker BM, Kutikov A, Guzzo TJ, Wein AJ.: Medscape. A case of synchronous bilateral testicular seminoma. [Case Report]  Nature Clinical Practice Urology 5(7): 397-401, July 2008.
  5. Alphs HH, Miles-Thomas J, Attenello F, Taube JM, Fonseca G, Guzzo TJ.: Presentation and management of a patient with subcutaneous metastatic transitional cell carcinoma of the bladder. [Case Report]  Nature Clinical Practice Urology  5(12): 691-694, Dec 2008.
  6. Bivalacqua TJ, Bagga HS, Patil K, Magheli A, Taube JM, Guzzo TJ, Gonzalgo ML.: Urethral carcinosarcoma from bladder carcinosarcomatous lesions: Analysis of clinico-pathologic features. [Case Report]  Canadian Journal of Urology  16(1): 4512-4515, Feb 2009.
  7. Mayer WA, Resnick MJ Canter D, Ramchandani P, Kutikov A, Harryhill JF, Carpiniello VL, Guzzo TJ.: Synchronous metastatic renal cell carcinoma to the genitourinary tract: Two rare case reports and review of the literature. [Case Report]  Canadian Journal of Urology  16(2): 4611-4614, Apr 2009.
  8. Guzzo TJ, Gonzalgo ML: Addictions in malignancy.  Addictions in Medicine: Principles and Practice [In press] Miller N (eds.). New York: John Wiley & Sons, 2009 Notes: Chap. 20.
  9. Guzzo TJ, Gonzalgo ML.: The impact of discordance between biopsy and pathologic Gleason scores on survival after radical prostatectomy. [Editorial Comment]  Journal of Urology  181: 104, 2009.
  10. Guzzo TJ, Gonzalgo ML.: Toward image guided robotic surgery: System validation.[Editorial Comment]    Journal of Urology 181: 789-790, 2009.
  11. Schaeffer EM, Guzzo TJ, Netto G, Kouzi R, Furge KA, Westphal M, Dykema K, Yang XJ, Zhou M, Argani P, The BT, Pavlovich CP.  : Renal medullary carcinoma: Molecular, pathologic and clinical evidence for treatment with topoisomerase inhibiting therapy. [Case Report]  British Journal of Urology  106(1): 62-65, July 2010.
  12. Guzzo TJ: Take action: Comprehensive treatment considerations.   The Johns Hopkins Guide for Patients with Bladder Cancer  Gonzalgo ML (eds.). Johns Hopkins University Press, Page: 31-48, 2011 Notes: Chap. 3.
  13. Guzzo TJ: Be prepared: side-effects of treatment.   The Johns Hopkins Guide for Patients with Bladder Cancer  Gonzalgo ML (eds.). Baltimore: The Johns Hopkins University Press, Page: 31-48, 2011 Notes: Chap. 4.
  14. Matthews CH, Guzzo TJ: Renal cell carcinoma.   Radiation Oncology: A Question-Based Review.   Hristov B (eds.). Philadelphia: Lippincott Williams & Wilkins, Page: 414-418, 2011 Notes: Chap. 63.
  15. Redmond KJ, Guzzo TJ.: Testicular nonseminomatous germ cell tumor.   Radiation Oncology: A Question-Based Review.   Hristov B  (eds.). Philadelphia: Lippincott Williams & Wilkins, Page: 399-403, 2011 Notes: Chap.60.
  16. Guzzo TJ, Malkowicz SB.: Retroperitoneal tumors.  Campbell-Walsh Urology, 10th Edition Review.   McDougal WS, Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA, Ramchandani P  (eds.). Philadelphia: WB Saunders/ Elsevier, Page: 289-291, 2012 Notes: Chap. 52.
  17. Guzzo TJ.: Small renal masses: The promise of thulium laser enucleation partial nephrectomy. [Editorial Comment]  National Review in Urology  10(5): 259-260, May 2013.
  18. Guzzo TJ.: Small renal masses: The promise of thulium laser enucleation partial nephrec-tomy. [Editorial Comment] Nature Reviews: Urology  10(5): 259-260, May 2013.
  19. Harris AM, Guzzo TJ.: Complications particular to the elderly.   Primer of Geriatric Urology. Guzzo TJ, Drach GW, Wein AJ  (eds.). New York: Springer, Page: 65-76, 2013 Notes: Chap. 6.
  20. Pietzak EJ, Guzzo TJ.: Perioperative care of the geriatric patient.   Primer of Geriatric Urology.  Guzzo TJ, Drach GW, Wein AJ  (eds.). New York: Springer, Page: 43-64, 2013 Notes: Chap. 5.
  21. Resnick MJ, Guzzo TJ.: Urologic oncology. Primer of Geriatric Urology. Guzzo TJ, Drach GW, Wein AJ  (eds.). New York: Springer, Page: 95-124, 2013 Notes: Chap. 9.
  22. Kabarriti AE, Ramchandani P, Guzzo TJ.: Spontaneous urinary bladder perforation: An unusual presentation of diabetes mellitus. [Case Report]  Urology Case Reports  2(2): 43-44, Jan 2014.
  23. Kabarriti AE, Guzzo TJ, Wein AJ.: Prostate stromal tumor of uncertain malignant potential: Case report with five year follow up. [Case Report]  Urology Case Reports  2(3): 109-111, May 2014.
  24. Gray PJ, Guzzo TJ.: Renal cell carcinoma.  Radiation Oncology: A Question-Based Review.   in Hristov B, Lin SH  (eds.). Philadelphia: Lippincott Williams & Wilkins, Page: 429-434, 2014 Notes: Chap. 63.
  25. Smith ZL, Guzzo TJ.: Traditional radical prostatectomy.   Prostate Cancer: A Multidisciplinary Approach to Diagnosis & Staging.   Dicker AP, Kelly WK, Trabulsi EJ, Zaorsky N (eds.). New York: Demos Medical, Page: 143-148, 2014 Notes: Chap. 9.1.
  26. Thompson R, Guzzo TJ.: Testicular nonseminomatous germ cell tumors.  .):  Radiation Oncology: A Question-Based Review.   Hristov B, Lin SH (eds.). Philadelphia: Lippincott Williams & Wilkins, Page: 414-419, 2014 Notes: Chap. 60.
  27. Guzzo TJ, Vaughn DJ.  : Invasive and metastatic bladder cancer. Campbell-Walsh Urology, 11th Edition.  Wein AJ, Kavoussi LR, Novick AC, Partin AW, Peters CA (eds.). Philadelphia: Elsevier, 2015 (In press) Notes: Chap. 93.
  28. Guzzo TJ.  Kidney and ureter.: Kidney and ureter.   Gray's Anatomy, 41st Edition.  Standring S (eds.). 2015 (In press) Notes: Chap. 74.
  29. Pietzak EJ, Guzzo TJ.: Carcinoma of the urethra (male and female).   Glenn's Urologic Surgery Textbook, 8th Edition.   Graham SD Jr, Keane TE (eds.). Philadelphia: Lippincott Williams & Wilkins, 2015 (In press).
Books
  1. Guzzo TJ, Drach GW, Wein AJ.: Primer of Geriatric Urology. New York: Springer 2013.
  2. Hanno PM, Guzzo TJ, Malkowicz SB, Wein AJ.: Penn Clinical Manual of Urology, 2nd Edition. Philadelphia: Elsevier 2014.
Alternative Media
  1. Guzzo TJ.: Robotic-assisted laparoscopic radical prostatectomy.  Video made for and appears on The Oncology Nursing Society Prostate Cancer Webcourse 2010.
  2. Guzzo TJ.: What's new in muscle invasive bladder cancer.   Radio interview, Reach MD Satellite Radio. May 2011.
  3. Guzzo TJ.: Prostate cancer. MD Consult, on-line addition. 2011.
  4. Guzzo TJ.: The latest on prostate cancer screening.  Web interview on Practice Update Jun 2013.
  5. Sun F, Oyesanmi O, Fontanarosa J, Reston J, Guzzo TJ, Schoelles K: Therapies for clinically localized prostate cancer: Update of a 2008 systematic review [Internet].  Rockville, MD: Agency for Healthcare Research and Quality (US) Dec 2014.
 
Awards, Honors and Membership in Honorary Societies
2014  Mid-Atlantic Section Representative, AUA Leadership Program
 
2013 The Paul Rodin Leberman Teaching Award
(presented by the urology chief residents in recognition of excellence in resident education)
 
2013 Third Prize for Clinical Research, Philadelphia Urologic Society
 
2007   Outstanding Scholar in Urology Award
 
2007 Linda and Joel Appel Prostate Cancer Research Award
 
2006  Resident Achievement Award
(presented for outstanding laparoendoscopic surgery)
 
2006 Linda and Joel Appel Prostate Cancer Research Award
 
2005 Howard M. Pollack Award for Academic Excellence
(awarded to the University of Pennsylvania urology resident with the highest score on the annual in-service exam)
 
2005  Linda and Joel Appel Prostate Cancer Research Award
 
2005 First Prize for Clinical Research, Philadelphia Urologic Society Resident Prize Essay
 
2002 Alpha Omega Alpha

Dr. Thomas Guzzo

 
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