Daniel N. Holena, M.D.
Traumatology, Surgical Critical Care
and Emergency Surgery |
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- Profile Home
- Appointments
- Education
- Memberships
- Research
- Publications
Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street,
5 Maloney
Philadelphia, PA 19104
Administrative Assistant: Desiree Gatto
Administrative Telephone: 215-662-7320
Administrative Fax: 215-614-0375
Clinical Office:
The Trauma Center at Penn
3400 Spruce Street, 2 Dulles
Philadelphia, PA 19104
Clinical Telephone: 215-662-7320
Clinical Fax: 215-614-0375
Contact Information (internal use only)
daniel.holena@uphs.upenn.edu  |
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Dr. Daniel Holena is board certified in General Surgery and Surgical Critical Care. He received his General Surgery training at Cornell, and completed is fellowship in Trauma Surgery and Surgical Critical Care at the University of Pennsylvania. Dr. Holena specializes in the treatment of traumatic injury, emergency general surgery conditions, and surgical critical care. His research interests include outcomes after emergency general surgery and triage biomarkers in acute trauma. |
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| Faculty Appointments |
| 2009 - present |
Assistant Professor of Surgery at HUP
Perelman School of Medicine
Philadelphia, Pennsylvania |
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| Hospital and Administrative Appointments |
| 2008 - present |
Senior Administrative Fellow
Division of Trauma and Surgical Critical Care
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 2008 - present |
Attending Trauma Physician
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| 2008 - present |
Attending Intensivist, Penn e-lert eICU
Penn Presbyterian Medical Center
Philadelphia, Pennsylvania |
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| 2008 - present |
Attending Intensivist, Penn e-lert eICU
Pennsylvania Hospital
Philadelphia, Pennsylvania |
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| 2011 - present |
Physician Leader, Unit Based Clinical Leadership Silverstein 12
Hospital of the University of Pennsylvania |
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| 2011 - present |
Director of Surgical Rapid Response
Hospital of the University of Pennsylvania |
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| 2011 - present |
Director of Audiovisual Video Review, Division of Trauma |
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| 2011 - present |
Member, Clinical Emergencies Committee |
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| 2012 - present |
Member, ad hoc Code Improvement Committee |
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| Editorial Positions |
| 2011 - present |
Ad Hoc Reviewer, Injury |
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| 2011 - present |
Editor, Journal of Trauma and Treatment |
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| Education/Training |
| 1991 - 1995 |
B.Sc. McGill University
Montreal, Canada (Biology) |
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| 1998 - 2002 |
M.D. State University of New York at Stony Brook
Stony Brook, New York |
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| Postgraduate Training and Fellowship Appointments |
| 2002 - 2003 |
Internship in General Surgery
New York Presbyterian Hospital/
Weill-Cornell School of Medicine
New York, New York |
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| 2002 - 2007 |
Rotating Resident in Surgical Oncology
Memorial Sloan-Kettering Cancer Center
New York, New York |
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| 2003 - 2007 |
Resident in General Surgery
New York Presbyterian Hospital/
Weill-Cornell School of Medicine
New York, New York |
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| 2007 - 2009 |
Fellowship in Trauma and Surgical Critical Care
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania |
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| Other Appointments |
| 1998 - 2001 |
Student Representative, Class of 2002
State University of New York at Stony Brook School of Medicine
Stony Brook, New York |
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| 2008 - 2009 |
Instructor B in Surgery
University of Pennsylvania School of |
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| Memberships/Societies |
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| Memberships in Professional and Scientific Societies: |
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| National/International Societies: |
- Eastern Association for the Surgery of Trauma
- Society of Critical Care Medicine
- American College of Surgeons
- American Medical Association
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| Local/Regional Societies |
- Pennsylvania Medical Society
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| Publications |
| Research Publications, Peer Reviewed |
- Holena DN, Eachempati S, and Barie P. Biliary Tract Infections. In Rello J, Kollef MH, Diaz E, Rodriguez A, eds. Infectious Diseases in Critical Care. Second edition. Heidelberg. Springer-Verlag. 2007:595-605.
- Whalen W, Holena DN, Pryor JP. Cardiac Injury Severe blunt chest trauma leads to cardiac arrest. Journal of Emergency Medical Services 2008: 33;36-38.
- Weinberger LN, Holena DN, Powell EK, and Gracias V. Arc determination equals injury identification: trauma mantra applied to electrocution. Injury Extra 2008: 39; 389-391.
- Pieracci FM, Henderson P, Rodney JR, Holena DN, Genisca A, Ip I, Benkert S, Hydo L, Eachempati SR, Shou J, and Barie PS. MD, MBA. A Randomized, Double-blind, Placebo-controlled Trial of the Effects of Enteral Iron Supplementation on Anemia and Risk of Infection During Surgical Critical Illness. Surg Infect 2009: 10;9-19.
- Holena DN Tolstoy N, Mills AM, Fox A, and Levine J. Cooler heads prevail: A case of intractable intracranial hypertension after liver transplantation treated with therapeutic hypothermia. Am J Crit Care 21 (1): 75-76, 2011
- Holena DN, Hadler R, Wirtalla C, Carr BG, Morris JB, and Kelz RR. Teaching status: The impact on emergency and elective surgical care in the U.S. Annals of Surgery 253 (5): 1017-1023, May 2011.
- Mills AM, Edwards, MJ, Shofer FS, Holena DN, Abbuhl SB. Older Age and Analgesia Administration in Emergency Department Patients with Abdominal or Back Pain. West J Emerg Med. 2011 Feb;12(1):43-50
- Holena DN, Mills AM, Carr BG, Wirtalla C, Sarani B, Kim P, and Kelz RR. Transfer Status: A risk factor for Mortality in Patients with Necrotizing Fasciitis. Surgery, 150 (3) : 363-370, Sept 2011
- Pascual JL, Holena DN, Vella M Sicoutris C Chandrakaladharan B, Fox A, Sarani B, Sims C, and Schwab, CW. Short Simulation Training Improves Objective Skills In Established Advanced Practitioners Managing Emergencies On The Ward And Surgical Intensive Care Unit. J Trauma. 71 (2) , pp. 330-338
- Sakran JV, Holena DN, and Dickinson E. Collaboration makes survival possible for thoracic injury patient. Journal of Emergency Medical Services 33(8):28-31, March. 2012.
- Mollo A, E. Reinke CE, Nelson C, Holena DN, Kann B, Williams N, Bleier J, and Kelz RR. The Simulated Ward: Ideal for Training Clinical Clerks in an Era of Patient Safety. J Surg Research Available online 12 April 2012.
- Massey PR, Sakran JV, Sarani B, Sims CA, Pascual JP, Holena DN. Hyperbaric Oxygen Therapy In Patients With Necrotizing Soft Tissue Infections. J Surg Research. 172(2), 348.
- Tolstoy NS , Aized M , McMonagle MP, Holena DN, Pascual JL, Sonnad SS , Sims CA. Mineralocorticoid deficiency in hemorrhagic shock. J Surg Research, In Press
- Shashaty M, Gallop R, Meyer N, Lanken P, Holena DN, Localio R, Bellamy S, Kaplan S, and Christie J. African American race, obesity, and blood product transfusion are risk factors for acute kidney injury in critically ill trauma patients. Journal of Critical Care, In Press
- Holena DN, Netzer G, Localio R, Bellamy S, Gallop R, Meyer N, Shashaty M, Reilly PM, Lanken P, and Christie J. The Association of Early Transfusion with Acute Lung Injury in Severely Injured Patients. J Trauma In Press
- Holena DN, Stoddard D. Martin ND, Winters B, Casey J, Pascual JL, Sims CA, Sarani, B. Clinical Outcomes Following Invasive versus Non-Invasive Pre-Operative Stabilization of Closed Diaphyseal Femur Fractures. Eur J Trauma, In Press
- Georgoff P, Perales P, Laguna B, Holena DN, Sims CA. Colonic injuries and the damage control abdomen: does management strategy matter? J Surg Research, In Press
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| Reviews in Peer Reviewed Research Publications (print or other media) |
- Allen S, Holena DN, McCunn M, Kohl B, and Sarani B. A Review of the Fundamental Principles and Evidence Base in the Use of Extracorporeal Membrane Oxygenation (ECMO) in Critically Ill Adult Patients J Intensive Care Med 26 :13-26, Jan 2011
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| Current Projects |
- Holena DN and Sims C. Hormone concentration in banked blood products.
- Holena DN, McNicholas A, and Sarani B Initial lactate level does not predict injury severity or mortality in low-mechanism trauma.
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| Poster Presentations |
- Holena DN, Horan AM, Sonnad S, and Gracias V. Service of admission does not affect outcome in patients with combined head and extremity injuries. Pennsylvania American College of Surgeons Committee on Trauma, Oct.. 2008. Harrisburg, PA
- Holena DN. Multiple great vessel injuries. Philadelphia Day of Trauma Dec 2008, Philadelphia PA
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| Lectures by Invitation |
| Feb 23rd, 2010 |
Trauma Clinical Outreach, Landsdale Fire Rescue |
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| April 4th, 2010 |
“Penetrating extremity vascular trauma”
Bayhealth Medical Center,
Dover, DE |
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| June 16th, 2011 |
“Interhospital Transfer and the Quaternary Medical Center”
Mercy Suburban Medical Center, Norristown, PA |
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| Sept 13th, 2011 |
“Prehospital Care of the Trauma Patient”
Department of Homeland Security, Philadelphia PA |
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| Sept 20th, 2011 |
“Prehospital Care of the Trauma Patient”
Department of Homeland Security, Philadelphia PA |
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| Nov 5th, 2011 |
Moderator, Philadelphia Annual Day of Trauma |
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| Mar 14th, 2012 |
Trauma Clinical Outreach, Plymouth Medic 308 |
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