penn medicine
penn surgery
penn surgery home penn surgery clinical penn surgery education penn surgery research penn surgery administration

Rita C. Milewski, RPh, MD, PhD, FACS
Cardiovascular Surgery

 
  • Profile Home
  • Appointments
  • Education
  • Societies
  • Research
  • Publications
  • Awards

Administrative Office:
Hospital of the University of Pennsylvania
3400 Spruce Street
6 Silverstein Pavilion
Philadelphia, PA 19104
Administrative Assistant:
Administrative Phone: 215-662-2093
Administrative Fax: 215-243-3243
Patient Appointments: 215-662-2956

Clinical Offices:
Perelman Center for Advanced Medicine
Penn Heart and Vascular Center
East Pavilion, 2nd Floor
3400 Civic Center Boulevard
Philadelphia, PA 19104
Clinical Phone: 215-662-2093
Clinical Fax: 215-243-3243

Contact Information (internal use only)

rita.milewski@uphs.upenn.edu

 

Karianna (Rita) Milewski, MD, PhD is a Clinical Assistant Professor of Surgery in the Division of Cardiothoracic Surgery at the University of Pennsylvania School of Medicine. Dr. Milewski became a staff physician were she entered the Clinical Investigator Graduate Degree Program, which allowed clinicians to obtain their PhD while continuing clinical responsibilities. In 2004 she completed her PhD in Molecular Genetics and later received two Business Certificates for Business Essentials and Entrepreneurship, from Wharton Business School, to obtain skills necessary to manage a laboratory. In 2008 she completed an Aortic Surgery Fellowship at the Hospital of the University of Pennsylvania.

Dr. Milewski’s main areas of expertise are in aortic surgery, including endovascular and percutaneous valves. She also supervises both heart and lung organ procurements at the Hospital of the University of Pennsylvania. She is currently conducting both clinical and basic science aortic research. Dr. Milewski is initiating a Translational Center for Aortic Diagnosis and Therapeutic Intervention.

 
Faculty Appointments
01/01/14 - present   Assistant Professor of Surgery at HUP
Perelman School of Medicine, University of Pennsylvania
Philadelphia, Pennsylvania
 
2008 - 2013 Clinical Assistant Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2004 - 2007 Adjunct Assistant Professor of Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
Hospital and Administrative Appointments
2008 - 2013 Health System Clinician, University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2004 - 2006 Senior Research Investigator, University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
2004 - present  Active Physician, Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1996 - present  Contract Physician, Penn Presbyterian Medical Center
Philadelphia, Pennsylvania
 
Other Appointments
1996 - 1999 Clinical Instructor, Division of Cardiothoracic Surgery
University of Pennsylvania School of Medicine
Philadelphia, Pennsylvania
 
Education/Training
2006 - 2007 University of Pennsylvania, Wharton School of Business
WPWP Business Essentials Certificate
WPWP Entrepreneurship Certificate
Philadelphia, Pennsylvania
 
1997 - 2004 PhD - University of Pennsylvania
Philadelphia, Pennsylvania
 
1980 - 1984 MD - Northwestern University Medical School
Chicago, Illinois
 
1976 - 1980 BS - Purdue University College of Pharmacy
West Lafayette, Indiana
 
Postgraduate Training and Fellowship Appointments
2008 Aortic Surgery Fellow
Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania
 
1997 - 2004 PhD Candidate in Molecular Genetics
University of Pennsylvania Biomedical Graduate School
Philadelphia, Pennsylvania
 
1994 - 1996 Fellow in Cardiothoracic Surgery
Hospital of the University of Pennsylvania and Children's Hospital of Philadelphia Philadelphia, Pennsylvania
 
1993 - 1994 Congenital Cardiac Surgery Fellow
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania
 
1989 - 1993 Cardiothoracic Resident
State University of New York at Buffalo
Buffalo, New York
 
1986 - 1989 Surgical Resident, University of West Virginia
Charleston, West Virginia
 
1984 - 1986 Surgical Resident, University of Minnesota
Minneapolis, Minnesota
 
Memberships/Societies
 
National Societies
2012 - present  American College of Surgeons
 
2008 - present  Women in Thoracic Surgery
 
1996 - present Society of Thoracic Surgeons
 
1996 - present  American Heart Association
 
  Local/Regional Societies
2011 - present Metropolitan Philadelphia Chapter, American College of Surgeons
 
Research
 
 
 
 
 
 
 
 
 
 
Publications
 
Research Publications, peer reviewed
  1. Wessels JL, Bourland JD, Babbs CF, Milewski RC, Rockenhauser ME, Geddes LA.  Cardiac stroke volume: Calculation from the pneumocardiogram.  Medical Electronics Sept. 1980.
  2. Wessels JL, Bourland JD, Babbs CF, Milewski RC, Rockenhauser ME, Geddes LA.   Correlation of the cardiogenic air flow in the respiratory airway (i.e. pneumocardiogram) with left ventricular stroke volume in dogs.  Japanese Heart Journal 26(5):777-785, Sept. 1985.
  3. Lang D, Chen F, Milewski R, Li J, Lu M, Epstein JA.  Pax3 is required for enteric ganglia formation and functions with Sox 10 to modulate expression of C-Ret. Journal of Clinical Investigation 106(8): 963-971, Oct. 2000.
  4. Chen F, Kook H, Milewski R, Gitler A, Lu MM, Li J, Nazarian R, Schnepp R,  Kuangyu J, Biben C, Runke G, Mackay J, Novotny J, Schwartz R, Harvey RP, Mullins MC, Epstein JA.  HOP is an unusual homeobox gene that modulates cardiac development.  Cell 110(6):713-723, Sept. 20, 2002.
  5. Lang D, Brown C, Milewski R, Jiang YQ, Lu MM, Epstein JA.  Distinct enhancers regulate neural expression of Pax7.  Genomics 82(5):553-560, Nov. 2003.
  6. Milewski RC, Chi NC, Li J, Brown C, Lu MM, Epstein JA.  Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of TEAD2 as a regulator of Pax3.  Development 131(4):829-837, Feb. 2004.
  7. Szeto WY, Moser WG, Desai ND, Milewski RK, Cheung AT, Pochettino A, Bavaria JE.              Transapical deployment of endovascular thoracic aortic stent graft for an ascending aortic pseudoaneurysm.  Annals of Thoracic Surgery 89(2):616-618, Feb. 2010.
  8. Degenhardt KR, Milewski RK, Padmanabhan A, Miller M, Singh MK, Lang D, Engleka KA, Wu M, Li J, Zhou D, Antonucci N, Li L, Epstein JA.  Distinct enhancers at the Pax 3 focus can function redundantly to regulate neural tube and neural crest expressions. Developmental Biology 15:339(2):519-527, Mar. 2010.
  9. Milewski RK, Pacini D, Moser GW, Moeller P, Desai N, Cowie D, Szeto WY, Di Marco L, Pochettino A, Di Bartolomeo R, Bavaria JE.  Circulation management in proximal aortic surgery: Selective use of retrograde and antegrade cerebral perfusion in a modern era treatment algorithm.  Annals of Thoracic Surgery 89:1448-1457, May 2010.
  10. Milewski RK, Szeto WY, Pochettino A, Moser GW, Moeller P, Bavaria JE.   Have hybrid procedure replaced open aortic arch reconstruction in high risk patients: A comparative study of open arch debranching with endovascular stent graft placement and conventional open total and distal aortic arch reconstruction.  Journal of Thoracic & Cardiovascular Surgery 140(3):590-597, Sept. 2010.
  11. Bavaria J, Milewski RK, Baker J, Moeller P, Szeto W, Pochettino A. Classic hybrid evolving approach to distal arch aneurysms: Toward the zero solution. Journal of Thoracic & Cardiovascular Surgery 140 (6 Suppl):S77-80, Dec. 2010.
  12. Jassar AS, Bavaria JE, Szeto WY, Moeller PJ, Maniaci J, Milewski RK, Gorman JH 3rd, Desai ND, Gorman RC, Pochettino A. Graft selection for aortic root replacement in complex active endocarditis: Does it matter? Annals of Thoracic Surgery 93(2):480-487, Feb. 2012.
  13. Branchetti E, Milewski RK, Grau JB,  Seefried WF, Sainger, R, Poggio P, Gorman  RC, Gorman JH 3rd,  Bavaria JE, Acker MA,  Ferrari G.  Bicuspid aortic aneurysm: Role of CTGF on smooth muscle cell phenotype and matrix homeostasis.   Journal of Thoracic & Cardiovascular Surgery 2012 (in press).
  14. Branchetti E, Milewski RK, Grau JB, Sainger R, Poggio Paolo, Lai Eric, Gorman RC, Gorman JH 3rd, Bavaria JE, Ferrari G.  Alterations in vascular smooth muscle cell phenotype and tissue microstructure are associated with thoracic aortic aneurysms in bicuspid aortic valve patients.  Journal of Cellular Physiology 2012 (In press).
  15. Holmes KW, Maslen CVL, Kindem M, Kroner BL, Song HK, Ravekes W, Dietz HC, Weinsaft JW, Roman MJ, Devereux RB, Pyeritz RE, Bavaria J, Milewski K, Milewicz D, LeMaire SA, Hendershot T, Eagle KA, Tolunay HE, Desvigne-Nickens P, Silberbach M, for the GenTac Registry Consortium.  GenTAC registry report: Gender differences among individuals with genetically triggered thoracic aortic aneurysm and dissection. Am J Med Genet  A; 161A(4): 779-786, April 2013
  16. Rylski B, Bavaria JE, Beyersdorf F, Branchetti E, Desai ND, Milewski RK,  Szeto WY, Vallabhajosyula P, Siepe M, Kara FA. Type A aortic dissection in Marfan syndrome: Extent of initial surgery determines long-term outcome.  Circulation; 129(13):1381.6-, April 2014
  17. Rylski B, Blanke P, Beyersdorf F, Desai ND, Milewski RK, Siepe M, Kari FA, Czerny M, Carrel T, Schlensak C, Krüger T, Mack MJ, Brinkman WT, Mohr FW, Etz CD, Luehr M, Bavaria J. How does the ascending aorta geometry change when it dissects? J Am Coll Cardiology; 63(13):1311-9, April 2014
  18. Rylski B, Desai ND, Bavaria JE, Moser W, Vallabhajosyula P, Pochettino A, Szeto WY, Milewski RK. Type A aortic dissection after previous cardiac surgery: Results of an integrated surgical approach.  Ann Thorac Surg; 97(5): 1582-8, May 2014
  19. Rylski B, Desjardins B, Moser JW, Bavaria JE, Milewski RK. Gender-related changes in aortic geometry throughout life.  Eur J Cardiothorac Surg; 45(5):805-11, May 2014
  20. Rylski BN, Szeto WY, Bavaria JE, Branchetti E, Moser W, Milewski RK. Development of a single endovascular device for aortic valve replacement and ascending aortic repair. J Card Surg; 29(3):371-6, May 2014
  21. Della Corte A, Body SC, Booher AM, Schaefers JH, Milewski RK, Michelena HI, Evangelista A, Pibarot P, Mathieu P, Limongelli G, Shekar PS, Aranki SF, Ballotta A, Di Benedetto G, Sakalihasan N, Nappi G, Eagle KA, Bavaria JE. Frigiola A, Sundt TM; on behalf of the International Bicuspid Aortic Valve Consortium (BAVCon) Investigators.  Surgical treatment of bicuspid aortic valve disease: Knowledge gaps and research perspectives. J Thorac Cardiovasc Surg; 147(6): 1749-57, June 2014
  22. Rylski B, Desai ND, Bavaria JE, Vallabhajosyula P, Moser W, Pochettino A, Szeto WY, Milewski RK. Aortic valve morphology determines the presentation and surgical approach to acute type A aortic dissection.  Ann Thorac Surg; A 97(6):1991-6, June 2014
  23. Rylski B, Milewski RK, Bavaria JE, Vallabhajosyula P, Moser W, Szeto WY, Desai ND. Long-term results of aggressive hemiarch replacement in 534 patients with type A aortic dissection. J Thorac Cardiovasc Surg; July 2014 (Epub ahead of print)
  24. Rylski B, Bavaria JE, Milewski RK, Vallabhajosyula P, Moser W, Kremens E, Pochettino A, Szeto WY, Desai ND. Long-term results of neomedia sinus Valsalva repair in 489 patients with type A aortic dissection.  Ann Thorac Surg; 98(2):582-9, August 2014
  25. Rylski B, Szeto WY, Bavaria JE, Walsh L, Anwaruddin S, Desai ND, Moser GW, Herrmann HC, Milewski RK. Transcatheter aortic valve implantation in patients with ascending aortic dilatation: The procedure’s safety and mid-term follow-up. Eur J Cardiothorac Surg; 46(2):228-33, August 2014
  26. Rylski B, Branchetti E, Bavaria JE, Vallabhajosyula P, Szeto WY, Milewski RK, Desai ND. Modeling of predissection aortic size in acute type A dissection: More than 90% fail to meet the guidelines for elective ascending replacement.  J Thorac Cardiovasc Surg;  148(3): 944-948, September 2014
Abstracts (Past 3 Years)
  1. Milewski RK, Szeto WY, Pochettino A, Woo YJ, Moser G, Moeller P, Bavaria JE.  Extending the horizon: A comparative study of open distal arch repair to thoracic endovascular aortic repair with left carotid/subclavian artery bypass: optimal management of the distal aortic arch and proximal thoracic aorta in high risk patients.  The Society of Thoracic Surgeons, 2010.
  2. Milewski RK, Jassar AS, Pochettino A, Szeto WY, Desai ND, Moeller PJ, Gorman III JH, Gorman RC, Bavaria JE.  The reoperative aortic root: Degenerative failure vs. infectious destruction – outcomes of the “true redo-root” reconstruction.”  The American Association for Thoracic Surgery Aortic Symposium, New York, NY, Apr. 2010.
  3. Milewski RK, Jassar AS, Pochettino A, Szeto WY, Desai ND, Moeller PJ, Gorman JH III, Gorman RC, Bavaria JE.  The “true redo-root” reconstruction: Outcomes of degenerative failure vs. infectious destruction.  The Pennsylvania Association for Thoracic Surgery, Lake Buena Vista, FL, Oct. 2010.
  4. Jassar AS, Pochettino A, Maniaci J, Moeller P, Szeto W, Desai N, Milewski RK, Gorman JH III, Gorman RC, Bavaria JE.  Graft selection for aortic root replacement in active endocarditis: Does it matter? The Society of Thoracic Surgeons, 2011.
  5. Rylski B, Bavaria JE, Walsh E, Anwaruddin S, Desai ND, Moser GW, Herrmann HC, Milewski RK. Transaortic valve implantation in patients with ascending aortic dilatation: The procedure’s safety and mid-term follow-up.  European Association of Cardiothoracic Surgeons, Vienna, Austria, October 7, 2013
  6. Rylski B, Desjardins B, Moser GW, Bavaria JE, Milewski RK. Gender-related changes in aortic geometry throughout life.  European Association of Cardiothoracic Surgeons, Vienna, Austria, October 7, 2013
  7. Rylski B, Szeto WY, Bavaria JE, Moser GW, Milewski RK. Endovascular Wheat Procedure: A single device for transcatheter aortic valve replacement and ascending aortic repair. European Association of Cardiothoracic Surgeons, Vienna, Austria, October 8, 2013
  8. Rylski B, Desai ND, Bavaria JE, Moser GW, Vallabhajosyula P, Pochettino AP, Szeto WY, Milewski RK. Type A aortic dissection after previous cardiac surgery: Results of an integrated surgical approach. Southern Thoracic Surgery Association,  Phoenix, Arizona, November 1, 2013
 
Awards, Honors and Membership in Honorary Societies
2013 Clifford Van Meter President’s Award, Southern Thoracic Surgery Association
 
1996 American Heart Association Travel Grant Award
 
1984 Member, Rho Chi, National Pharmacy Scholastic Honorary
 
1984 Member, Alpha Lambda Delta, Scholastic Honorary
 
1980 Distinguished Graduate; National Dean's List, Purdue Top 500
 
1980 Honors in Pharmacology, Psychiatry and Vascular Surgery
 
1980 Graduate with Distinction, Purdue University

Dr. Rita Milewski

 
footer Terms of Use Legal Disclaimer Site Map Contact Us Financial Assistance About Penn Medicine Privacy Statement
penn medicine