Publications (last 4 years)
Chacko SK, DiSanto M, Zheng Y, Wein A.J.: Changes in the composition of myosin isoforms in smooth muscle hypertrophy following urinary bladder outlet obstruction. In, Bittar EE, Barr L, Christ GJ (eds) A Functional View of Smooth Muscle (Volume 8). Stamford, CT, Jai Press Inc., 8:81-100, 2000.

DiSanto ME, Wein A.J., Chacko S: Lower urinary tract physiology and pharmacology. Current Urology Reports 1:227-234, 2000.

Wein A.J.: Section Editor, Voiding Dysfunction. In, Kaplan SA, Chapple CR (eds), Current Urology Reports, Volume 1, Number 3, 2000.

Bernstein MR, Cangiano T, DAmico A, Chittams J, Hardy C, Whittington RD, Tomaszewski JE, Schnall MD, Wein A.J., Malkowicz SB: Endorectal coil magnetic resonance imaging and clinicopathologic findings in T1c adenocarcinoma of the prostate. Uro Onc. 5:104-107, 2000.

Wein A.J., Monga AK: Applied pharmacology. In Stanton SL, Monga AK (eds) Clinical Urogynaecology. London, Churchill Livingstone, pp. 487-520, 2000.

Rovner ES, Gomes CM, Banner MP, Wein A.J.: Ventral hernia of the urinary bladder with mixed urinary incontinence: treatment with herniorrhaphy and allograft fascial sling. Urology 55, (1):145, 2000.

Abrams P, Wein A.J., (guest editors). Overactive bladder and its treatments consensus conference. Urology 55 (Supp. 5A), 2000.

Abrams P, Wein A.J.: Introduction: Overactive bladder and its treatments. Urology 55 (Supp. 5A), pp. 1-3, 2000.

Wein A.J.: Closing remarks. Urology 55 (Supp. 5A), pp. 83-84, 2000.

Whittington R, Malkowicz SB, Schultz D, Fondurulia J, Chen M-H, Tomaszewski JE, Renshaw AA, Wein A.J., Richie JP: Clinical utility of the percentage of positive prostate biopsies in defining biochemical outcome after radical prostatectomy for patients with clinically localized prostate cancer. J Clin Onc 18:6, 1164-1172, 2000.

Chancellor M, Freedman S. Mitcheson HD, Antoci J, Primus G, Wein A: Tolterodine, an effective and well tolerated treatment for urge incontinence and other overactive bladder symptoms. Clin Drug Invest, 2 (2):83-91, 2000.

Rovner ES, Wein A.J.: Todays treatment of overactive bladder and urge incontinence. Womens Health Primary Care 3(3):179-186, 2000.

Rovner ES, Wein A.J.: Overactive bladder and urge incontinence: establishing the diagnosis. Womens Health Primary Care, 3(2):117-126, 2000.

Rovner ES, Wein A.J.: How to regain control over your overactive bladder. Womens Health Primary Care 3(3), 189-192, 2000.

Jaffe JM, Malkowicz SB, Walker AH, MacBride S, Peschel R, Tomaszewski J, Van Arsdalen K, Wein A.J., Rebbeck TR: Association of SRD5A2 genotype and pathological characteristics of prostate tumors. Cancer Research 60:1626-1630, 2000.

Sanchez-Ortiz RF, Broderick GA, Rovner ES, Wein A.J., Whittington R, Malkowicz SB: Erectile function and quality of life after interstitial radiation therapy for prostate cancer. Int. J. of Impotence Research, 11(3):S1-S7, 2000.

Wein A.J.: Editorial Consultant, Clinical Urography (Second Edition). Pollack HM, McClennan BL (eds). Philadelphia, PA, WB Saunders, Co., 2000.

Wein A.J.: Section Editor, Neuromuscular disorders (neurourology) In, Clinical Urography (Second Edition). Pollack HM, McClennan BL (eds). Philadelphia, PA, WB Saunders, Co., (1):S8-2271-2282, 2000.

Wein A.J.: Overview of voiding function and dysfunction: relevant anatomy, physiology, pharmacology, classifications and definitions. In, Pollack HM, McClennan BL (eds), ClinicalUrography (Second Edition). Philadelphia, PA, WB Saunders Co., 2000, pp. 2272-2282.

Wein A.J., Rovner ES: Pathophysiology and classification of voiding dysfunction. In, Appell RA (ed): Voiding Dysfunction Diagnosis and Treatment. Totowa NJ, Humana Press, Inc., 2000, pp. 3-24.

Wein A.J.: Criteria for assessing outcome following intervention for benign prostatic hyperplasia. In, Lepor H (ed) Prostatic Diseases. Philadelphia, PA, WB Saunders Co., 2000, pp. 210-231.

Gomes CM, Broderick GA, Sanchez-Ortiz RF, Preate D Jr., Rovner ES, Wein A.J.: Artificial urinary sphincter for post-prostatectomy incontinence: impact of prior collagen injection on cost and clinical outcome. J Urol, 163:87-90, 2000.

Groutz A, Blaivas JG, Chaikin DC, Resnick NM, Engleman K, Anzalone D, Bryzinski B, Wein A.J.: Noninvasive outcome measures of urinary incontinence and lower urinary tract symptoms. A multicenter study of micturition diary and pad tests. J Urol 164:698-701, 2000.

Rebbeck TR, Walker AH, Ziegler-Johnson C, Weisburg S, Martin A, Nathanson K, Wein A.J., Malkowicz SB: Association of HPC2/ELAC2 genotypes and prostate cancer. Am J Hum Genet. 67:1014-1019, 2000.

Blander DS, Sanchez-Ortiz, RF, Wein A.J., Broderick GA: Efficacy of sildenafil in erectile dysfunction after radical prostatectomy. Intl J. of Impotence Research 12:165-168, 2000.

Rovner ES, Wein A.J.: Modern pharmacotherapy of urge urinary incontinence in the USA: tolterodine and oxybutynin. BJU international, 86 (2):44-54, 2000.

Early J, Gomes C, DiSanto ME, Wein A.J., Chacko S: Decreased contractility of detrusor smooth muscle from diabetic rabbits is associated with translocation of protein kinase C. Biophys. J. 78:113A, 2000.

Chacko S, Hypolite J, DiSanto M, Wein A.J.: Myosin light chain phosphorylation at resting level and the composition of myosin isoforms in the bladder body and urethra. Scand J Urol Nephol Suppl. 203:46-50, 2000.

Kelada SN, Karadia SL, Walker AH, Wein A.J., Malkowicz SB, Rebbeck TR: The glutathione S-transferase-and T genotypes in the etiology of prostate cancer: genotype environment interactions with smoking. Cancer, Epidemiology, Biomarkers & Prevention, 9:1329-1334, 2000.

DAmico AV, Whittington R, Malkowicz SB, Schultz D, Silver B, Henry L, Hurwitz M, Kaplan I, Beard CJ, Tomaszewski, JE, Renshaw AA, Wein A, Richie JP: Investigating the clinical utility of the percent of positive prostate biopsies in predicting PSA outcome following local therapy for patients with clinically localized prostate cancer. Prostate Cancer and Prostatic Diseases, 3:259-264, 2000.

Chacko S, Hypolite J, DiSanto M, Wein A.J.: Myosin light chain phosphorylation at resting level and the composition of myosin isoforms in the bladder body and urethra. Scand. J Urol Nephrol Suppl. 203:46-50, 2000.

Chang S, Hypolite JA, Wein A.J., Chacko S, DiSanto ME: Expression of myosin light chain kinase and Rho-associated kinase in corpus cavernosum smooth muscle. Biophys. J. 78:24A, 2000.

Gomes CM, DiSanto ME, Horan P, Levin RM, Wein A.J., Chacko S: Improved contractility of bladders after tadenen treatment is associated with reversal of altered myosin isoform expression. J Urol 163:2008-2013, 2000.

Maki DD, Banner MP, Ramchandani P, Stolpen A, Rovner ES, Wein A.J.: Injected periurethral collagen for postprostatectomy urinary incontinence: MR and CT appearance. Abdominal Imaging 25(6):658-662, 2000.

Metro MJ, Ramchandani P, Banner MP, Siegelman ES, Stolpen AH, Wein A.J., Rovner ES: Angiomyolipoma of the renal sinus: Diagnosis by percutaneous biopsy. Urology 55(2):286-289, 2000.

Rovner ES, Propert KJ, Brensinger C, Wein A.J., Foy M, Kirkemo A, Landis JR, Kusek JW, Nyberg LM and the ICDB Study Group: Treatments used in women with interstitial cystitis: The interstitial cystitis database (ICDB) study experience. Urology, 56:940-945, 2000.

Wein A.J.: Overactive bladder: defining the disease. Am J Managed Care, 6 (suppl):S559-564, 2000.

DAmico AV, Whittington R, Malkowicz SB, Schultz D, Tomaszewski JE, Wein A.J.: Prostate specific antigen outcome based on the extent of extracapsular extension and margin status in patients with seminal vesicle negative prostate carcinoma of Gleason score [ 7. Cancer, 88:2110-2115, 2000.

DAmico AV, Whittington R, Malkowicz SB, Wu YH, Chen MH, Hurwitz M, Kantoff PW, Tomaszewski JE, Renshaw AA, Wein A.J., Richie JP: Utilizing predications of early prostate specific antigen failure to optimize patient selection for adjuvant systemic therapy trials. J of Clin Onc, 18:3240-3246, 2000.

Kirby R, Aarnick R, Abboo C, Babaian R, Damiao R, Kiely P, Parkinson C, Edson-Pontes J, Resnick M, deReijke TM, Wein AJ: Diagnosis and staging of prostate cancer. In Murphy GP, Khoury S, Partin A, Denis L (eds), Prostate Cancer, 2nd International Consultation, Plymgridge Distributors, Plymouth, UK, 2000, pp 235-263.

Cheung R, Altschuler MD, DAmico AV, Malkowicz SB, Wein A.J., Whittington R: ROC optimization may improve stratification of prostate cancer patients. Urology 57:286-290, 2001.

Hypolite J, DiSanto M, Zheng Y, Chang S, Wein A.J., Chacko S: Regional variation on myosin isoforms and phosphorylation at the resting tone in urinary bladder smooth muscle. Am J. Physiol (Cell) 280:C254-259, 2001.

Resnick M, Ackermann R, Bosch J, Cidre J, Foo K, Frank I, Koyanagi T, Palmtag H, Price D, Vallancien G, Vaughan E, Wein A: Initial evaluation of LUTS. In, Chatelain C, Denis L, Foo KT, Khoury S, McConnell J (eds): Benign Prostatic Hyperplasia. Plymouth, UK, Heath Publications Ltd., 2001, pp.167-200.

Gomes CM, Sanchez-Ortiz R, Harris C, Wein A.J., Rovner ES: Significance of hematuria in patients with interstitial cystitis: review of radiographic and endoscopic findings. Urology, 57(2):262-265, 2001.

Sanchez-Ortiz R, Wang Z, Menon C, DiSanto M, Wein A.J., Chacko S: Estrogen modulates the expression of myosin heavy chain in detrusor smooth muscle. Am J Physiol-Cell Physiology. 280:C433-C440, 2001.

VanKerrebroeck P, Kreder K, Jonas U, Zinner N, Wein A, On behalf of the tolterodine study group: Tolterodine once daily: superior efficacy and tolerability in the treatment of the overactive bladder. Urology 57:414-421, 2001.

Abrams P, Wein A: Recent advances: Urology. BMJ, 321:1393-1396, 2001.

Blander DS, Rovner ES, Schnall M, Ramchandani P, Banner MP, Broderick GA, Wein A.J.: Endoluminal magnetic resonance imaging in the evaluation of urethral diverticula in females. Urology 57(4):660-665, 2001.

674. Gomes CM, Rovner ES, Banner MP, Ramchandani P, Wein A.J.: Simultaneous upper and lower urinary tract obstruction associated with severe genital prolapse: Diagnosis and evaluation with magnetic resonance imaging. International Urogynecology J., 12:144-146, 2001.

Abrams P, Malone-Lee J, Jacquetin B, Wyndaele J-J, Tammela T, Jonas U, Wein A: Twelve month treatment of overactive bladder: Efficacy and tolerability of tolterodine. Drugs and Aging, 18(7):551-562, 2001.

Arafat HA, Kim GS, DiSanto ME, Wein A.J., Chacko S: Heterogeneity of bladder myocytes in vitro: modulation of myosin isoform expression. Tissue & Cell, 33(3):219-232, 2001.

Wein A.J., Rovner ES: Pharmacologic management of the overactive bladder. Contemporary Urology, Suppl. 6:22-35, June, 2001.

Appell RA, Abrams P, Drutz HP, VanKerrebroeck PEVA, Millard R, Wein A: Treatment of overactive bladder: long-term tolerability and efficacy of tolterodine. World J Urol 19:141 -147, 2001.

Malkowicz SB, McKenna WG, Vaughn DJ, Wan SX, Propert KJ, Rockwell K, Marks SHF, Wein A.J., Kennedy AR: Effects of Bowman-Birk inhibitor concentrate (BBIC) in patients with benign prostatic hyperplasia. The Prostate, 48:16-28, 2001.

Ricci JA, Baggish JS, Hunt TL, Stewart WF, Wein A.J., Herzog AR, Diokno AC: Coping strategies and health care seeking behavior in a US national sample of adults with symptoms suggestive of overactive bladder. Clinical Therapeutics 23(8), 1245-1253, 2001.

DAmico AV, Whittington R, Malkowicz AB, Renshaw AA, Tomaszewski JE, Bentley C, Schultz D, Rocha S, Wein A, Richie JP: Estimating the impact on prostate cancer mortality of incorporating prostate-specific antigen testing into screening. Urology, 58:406-410, 2001.

Cheung R, Altschuler MD, DAmico AV, Malkowicz SB, Wein A.J., Whittington, R: Using the receiver operating characteristic curve to select pretreatment and pathologic predictors for early and late postprostatectomy PSA failure. Urology 58:400-405, 2001.

Milsom I, Abrams P, Cardozo L, Roberts RG, Throff J, Wein A.J.: How widespread are the symptoms of an overactive bladder and how are they managed? A population-based prevalence study. BJU International, 87:760-766, 2001.

Gomes CM, Sanchez-Ortiz RF, Harris C, Wein A.J., Rovner ES: Significance of hematuria in patients with interstitial cystitis: Review of radiographic and endoscopic findings. Urology, 57:262-265, 2001.

Andersson KE, Chapple C, Wein A: The basis for drug treatment of the overactive bladder. World J Urol, 19:294-298, 2001.

Wein A.J., Rovner ES: Voiding function and dysfunction. In, Hanno PM, Malkowicz BM, Wein A.J. (eds), Clinical Manual of Urology, Third Edition. New York, McGraw-Hill, 2001, pp. 337-436, 2001.

Wein A.J., Rovner ES: Benign prostatic hyperplasia. In, Hanno PM, Malkowicz BM, Wein A.J. (eds), Clinical Manual of Urology, Third Edition. New York, McGraw-Hill, 2001, pp. 437-470.

Malkowicz SB, Wein A.J.: Adult Genitourinary Cancer. In, Hanno PM, Malkowicz BM, Wein A.J. (eds), Clinical Manual of Urology, Third Edition. New York, McGraw-Hill, 2001, pp. 471-487.

Wein A.J.: Pharmacological agents for the treatment of urinary incontinence due to overactive bladder. Exp. Opin,. Invest. Drugs 10(1):65-83, 2001.

Liberman JN, Hunt TL, Stewart WF, Wein A, Zhou Z, Herzog AR, Lipton RB, Diokno AC: Health-related quality of life among adults with symptoms of overactive bladder: Results from a US community-based survey. Urology, 57:1044-1050, 2001.

Arafat HA, Wein A.J., Chacko S: Osteopontin gene expression and immunolocalization in the rabbit urinary tract. J Urol, 167:746-752, 2001.

Arafat, H.A., Kim, G., DiSanto, M.E., Wein, A.J., Chacko, S: Heterogeneity of bladder myocytes in vitro: modulation of myosin isoform expression. Tissue and Cell. 33:219-232, 2001.

Sanchez-Ortiz, R., Wang, Z., Menon, C., DiSanto, M.E., Wein, A.J., Chacko, S: Estrogen modulates the expression of myosin heavy chain in detrusor smooth muscle. American J. of Physiology:Cell, 280: C433-C440, 2001.

Hypolite, J., DiSanto, M.E., Zheng, Y. Wein, A.J., Chacko, S: Regional variation in myosin isoforms and phosphorylation at the resting tone in urinary bladder smooth muscle. American J. of Physiology:Cell. 280:C254-C264, 2001.

Rovner, ES and Wein, A.J.: Drug Treatment of voiding dysfunction in women. (Textbook of Female Urology and Urogynaecology, Cardozo L and Staskin, D, Isis Medical Media Ltd, 7-7 Pratt Street, London NW1 OAE, 2001), Section IV, 32 Treatment of Incontinence, Prolapse and Related Conditions, 2001, pp 359-408.

Wein A.J.: Pathophysiology and Categorization of Voiding Dysfunction. Objectives for Urology Residency Education. 5th Edition. Soc University Urology, 156-157, 2001.

Wein A.J.: Neurourologic and Urodynamic Assessment of the Lower Urinary Tract. Objectives for Urology Residency Education. 5th Edition. Soc University Urology, 158-164, 2001.

Wein A.J.: Neuromuscular Dysfunction of the Lower Urinary Tract in the Adult and its Treatment. Objectives for Urology Residency Education. 5th Edition. Soc University Urology, 165-170, 2001.

Sanchez-Ortiz RF, Wein A.J., and Malkowicz SB: Benign and Malignant tumors of the renal pelvis and ureter. Objectives for Urology Residency Education. 5th Edition. Soc University Urology, 269-271, 2001.

Steers WD, Barrett DM, Wein A.J.: Voiding dysfunction: diagnosis, classification and management. In, Gillenwater JY, Grayhack JT, Howards SS, Mitchell ME (eds), Adult and Pediatric Urology, Fourth Edition. Philadelphia, Lippincott Williams & Wilkins, 2002, pp. 1115-1216.

Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, vanKerrebroeck P, Victor A, Wein A: The standardisation of terminology of lower urinary tract function: Report from the standardisation subcommittee of the International Continence Society. Neurourology and Urodynamics, 21:167-178, 2002.

Abrams P, Wein A.J.: The impact of overactive bladder on patients and society, and current approaches to treatment. Monograph prepared for Yamanouchi Europe BV, 2002, pp., 1-15.

Rovner ES, Wein A.J.: Once-daily, extended-release formulations of antimuscarinic agents in the treatment of overactive bladder: A review. European Urology 41:6-14, 2002.

Robnett, T.J., Whittington, R., Malkowicz, S.B., Brereton, H.D., Van Arsdalen, K., Drach, G., Wein, A.J.: Long-Term Use of Combined Radiation Therapy and Hormonal Therapy in the Management of Stage D1 Prostate Cancer. Int. J. Radiation Oncology Biol. Phys., 53:1146-1151, 2002.

Rovner, E, Wein, A.J.: The Treatment of Overactive Bladder in the Geriatric Patient, Clinical Geriatrics 10:1-12, 2002.

Wein, A.J.: Pathophysiology and Categorization of Voiding Dysfunction. In, Walsh, P., Retik, A., Vaughan, E.D., Jr., Wein, A.J. (eds): Campbells Urology, Eighth Edition, Saunders, Philadelphia, pp. 887-898, 2002.

Wein, A.J.: Neuromuscular Dysfunction of the Lower Urinary Tract and Its Treatment. In, Walsh, P., Retik, A., Vaughan, E.D., Jr., Wein, A.J. (eds): Campbells Urology, Eighth Edition, Saunders, Philadelphia, 2002, pp. 931-966.

Margolis DJ, Wein A.J.: Color Atlas of Genital Dermatology. In Walsh, P., Retik, A., Vaughan, E.D., Wein, A.J. (eds): Campbells urology, Eighth Edition, WB Saunders, Philadelphia, pp 731-742, 2002.

Wein, A.J.: Pathophysiology and Categorization of Voiding Dysfunction. In, Walsh, P., Retik, A., Vaughan, E.D., Jr., Wein, A.J. (eds): Campbells Urology Study Guide, 2nd edition, Saunders, Philadelphia, 2002, pp. 85-88.

Wein, A.J.: Neuromuscular Dysfunction of the Lower Urinary Tract. In, Walsh, P., Retik, A., Vaughan, E.D., Jr., Wein, A.J. (eds): Campbells Urology Study Guide, 2nd edition, Saunders, Philadelphia, 2002, pp. 85-88.

Shaohua C, Hypolite, JA, Zderic A, Wein, A.J., Chacko, S and DiSanto, ME: Enhanced Force Generation by Corpus Cavernosum Smooth Muscle in Rabbits with Partial Bladder Outlet Obstruction. J Urol, 167:2636-2644, 2002.

Andersson, KE, Appell, R, Awad, S, Chapple, C, Drutz, H, Finkbeiner, A, Fourcroy, Haab, F, Wein, A.J.: Pharmacological Treatment of Urinary Incontinence. In Abrams P, Cardozo L, Khory S, Wein a. Incontinence, 2nd Edition, Plymbridge Distributors, Plymouth UK, 2002, pp 479-513.

Rovner ES, and Wein, A.J.: Practical Urodynamics, Part I. AUA Update Series, American Urological Association, Inc., Volume XX1 (19):146-151, 2002.

Rovner ES, and Wein, A.J.: Practical Urodynamics, Part II. AUA Update Series, American Urological Association, Inc., Volume XX1 (20):154-159, 2002.

Zheng, Y., Weber, W.T., Wang, S., Wein, A.J., Zderic, S.A., Chacko, S., DiSanto, M.E.:. Generation of a cell line with smooth muscle phenotype from hypertrophied urinary bladder. Am. J. of Physiology:Cell, 283:C373-C382, 2002.

Chang, S., Hypolite, J.A., Zderic, S.A., Wein, A.J., Chacko, S., DiSanto, M.E.: Enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction. J. Urol., 167:2636-2644, 2002.

Rovner, E.S., and Wein, A.J.: Evaluation and management of overactive bladder in the elderly. Clinical Geriatrics, 10(1): 20-35, 2002.

Wein A.J., Lose G.R., Robertson G.L.: Nocturia in Men, Women and the Elderly: a practical approach. Brit J Urol Int., 90(3):28-31, 2002.

Wein A.J, Abrams P.: Statement from the First International Consultation on Nocturia: reaching for a consensus. Brit J. of Urol Int., 90(3):37, 2002.

Staskin D.R., Wein A.J., Andersson K.E., Bauer S.B., Blaivas J.G., Burgio K.L., Cardozo L., Chapple C.R., Dmochowski R.R., Gupta S., Mostwin J.L., Ouslander J.G., Weiss J.P., and King L: Overview Consensus Statement. J. Urol. 60:5A (suppl):1-6, 2002.

Rovner E.S., and Wein, A.J.: Pharmacologic Management of Urinary Incontinence in Women., Urol. Clinics North America 2002; 29:537-550.

Wein A.J., and Rovner E.S.: Definition and Epidemiology of Overactive Bladder. J. Urol. 60:5A (suppl):7-12, 2002.

Books (last 4 years)
Wein AJ, Flanigan R, Resnick M (eds): Objectives for Urologic Residency Education. Society University Urologists, 2001.

Hanno PM, Malkowicz SB, Wein AJ: A Clinical Manual of Urology, Third Edition, McGraw-Hill, New York, 2001.

Rovner, ES, Wein, AJ, Caruso, D: A Womans Guide To Regaining Bladder Control: Everything you need to know for the diagnosis and cure of incontinence., M. Evans and Co, Inc., New York, 2002.

Abrams, P, Cardozo, L, Khoury, S, Wein, AJ: Incontinence. Health Publication Limited, Plymbridge Distributors, Ltd, 2nd Edition, 2002.

Walsh P, Retik A, Vaughan, ED, Jr., Wein, AJ: (eds): Campbells Urology, 8th Edition, Saunders, Philadelphia, 2002.

Walsh P, Retik A, Vaughan ED, Jr., Wein AJ (eds): Campbells Urology Study Guide, 2nd Edition, Saunders, Philadelphia, 2002.

Abstracts, Editorials (Unassociated with other publications, not including editorial comments)
Wein AJ, Roberts RW: Overactive bladder survey: evaluates the extent of symptoms in family doctor setting. Family Urology, 1:7, 2000.

Wein AJ: Overactive bladder: defining the disease. Am J Managed Care 6 (11):S559-S564, 2000.

Wein AJ (Co-Chairman), American Urological Association Annual Postgraduate Seminar. Dallas, TX, March 9-12, 2000. Physiology of micturition; Pathophysiology of voiding dysfunction; Voiding dysfunction in neurologic disease and injury.

Wein AJ (Invited Lecturer): Basic Science Course sponsored by AUA Office of Education. Charlottesville, VA, June 14, 2000. Physiology and pharmacology of the lower urinary tract; Evaluation of voiding dysfunction; Classification of voiding dysfunction; Voiding dysfunction associated with neurologic disease; Management of voiding dysfunction.

Sanchez-Ortiz R, Broderick GA, Rovner ES, Whittington R, Wein AJ: Relationship between erectile function and quality of life after interstitial radiation therapy for prostate cancer. AUA Mid-Atlantic Sectional Meeting, Rio Mar Puerto Rico, October 15, 2000.

Sanchez-Ortiz R, Rovner ES, Broderick GA, Wein AJ: Erectile function and health related quality of life after interstitial radiation therapy for prostate cancer. Annual meeting, American Urological Association, Atlanta, GA, April 2000.

Early J, Gomes C, DiSanto ME, Wein AJ,Chacko SK: Decreased contractility of detrusor smooth muscle from diabetic rabbits is associated with translocation of protein kinase C. Biophys. J. 78:113A, 2000.

DiSanto, M.E., Zheng, Y., Stein, R., Zderic, S., Wein, A.J., and Chacko, S.K. 2000. Decompensated Detrusor Smooth Muscle in Partial Bladder Obstruction Shows an Overexpression of Myosin Isoform SM-A which Utilizes Less ATP During Actin Myosin Interaction and Force Generation. American Urological Association Annual Meeting. Journal of Urology. 163: 248A.

Xu, D., DiSanto, M.E., Hypolite, J.A., Barsotti, R.J., Wein, A.J., and Chacko, S.K. 2000. Mechanisms for Urinary Continence: A Correlation Between Smooth Muscle Myosin Isoform and Shortening Velocity on Different Layers of Rabbit Urethra. American Urological Association Annual Meeting. Journal of Urology. 163: 42A.

Earley, J.J., Gomes, C.M., DiSanto, M.E., Wein, A.J., and Chacko, S. 2000. Mechanism for the Diabetes-Induced Decrease in Detrusor Contractility Involves Translocation of Protein Kinase C Isoforms. American Urological Association Annual Meeting. Journal of Urology. 163: 229A.

Chang, S., Hypolite, J.A., Wein, A.J., Chacko, S.K., DiSanto, M.E. 2000. Expression of Myosin Light Chain Kinase and Rho-associated kinase in Corpus Cavernosum Smooth Muscle. Biophysical Society Annual Meeting. Biophysical Journal. 78: 24A.

Earley, J.J., Gomes, C., DiSanto, M.E., Wein, A.J. and Chacko, S. 2000. Decreased Contractility of Detrusor Smooth Muscle From Diabetic Rabbits is Associated With Translocation of Protein Kinase C b2. Biophysical Society Annual Meeting. Biophysical Journal. 78:113A.

Xu DG, DiSanto ME, Hypolite JA, Chacko SK, Barsotti RJ: Expression of smooth muscle myosin SM-B isoform in different layers of rabbit urethra correlates with shortening velocity. Biophys. J., 87:117A, 2000.

Chang S, Hypolite JA, Wein AJ, Chacko SK, DiSanto ME: Expression of myosin light chain kinase and Rho-associated kinase in corpus cavernosum smooth muscle. Biophys. J., 78:24A, 2000.

Nehra A, Rovner ES, Wein AJ, Lange P, Ellis W, Keane T, McCammon K: Interim analysis of a multicenter study of extracorporeal magnetic innervation (ExMI) for the treatment of urinary incontinence following radical prostatectomy. International Bladder Symposium, Washington, DC, March 16, 2001.

Chacko S, Changolkar AK, Kesavanm P, Arafat H, Zheng Y, DiSanto ME, Wu HY, Bing W, Zderic SA, Wein AJ: Ablation of functional domains in the C-terminal region of caldesmon in mice by homologous recombination. Biophys. J., 80:341A, 2001.

Wein AJ (Co-Director) American Urological Association Annual Postgraduate Seminar. Chicago, IL, March 22-24, 2001. Physiology of micturition; Pathophysiology of voiding dysfunction; Neuropathic voiding dysfunction: Voiding dysfunction associated with neurologic disease.

Zhang E, Stein R, Zderic SA, Wein AJ, Chacko S: Overexpression of non-muscle caldesmon in hypertrophied bladder smooth muscle cells. Biophys J,., 80:358A, 2001.

Arafat HA, Kim G, DiSanto ME, Wein AJ, Chacko S: Heterogeneity of bladder myocytes in vitro: modulation of myosin isoform gene expression. Biophys. J. 80:388A, 2001.

Bing W, DiSanto ME, Zderic SA, Wein AJ, Chacko S: Changes in myosin light chain kinase and phosphatase activities in hypertrophied smooth muscle. Biophys. J., 80:389A, 2001.

Chang S, Hypolite JA, Changolkar A, Wein AJ, Chacko S, DiSanto ME: The mechanism of diabetes-induced erectile dysfunction involves an increased sensitivity to endothelin-1 resulting from overexpression of endothelin B receptors in the corpus cavernosum of the penis. Diabetes 50:A92, 2001.

DiSanto ME, Chang S, Hypolite J, Zderic SA, Wein AJ, Chacko S: Enhancement of force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction. Intl. J. Impot. Res. 13:S40, 2001.

DiSanto ME, Chang S, Hypolite J, Zderic SA, Wein AJ, Chacko S: Alteration of corpus cavernosum smooth muscle contractility: A mechanism for diabetes-induced erectile dysfunction. Intl. J. Impot. Res. 13:S14, 2001.

Bittorf B, Kessler H, Merkel S, Bruckl W, Wein AJ, Ballhausen WG, Hohenberger W, Gunther K: Multiple primary malignancies: An epidemiological and pedigree analysis of 57 patients with at least three tumours, European Journal of Surgical Oncology. 27 (3):302-13, 2001.

Appell RA, Abrams P, Drutz Hp, VanKerrebroeck, PE, Millard R, Wein A: Treatment of overactive bladder: long-term tolerability and efficacy of Tolterodine. Clinical Trial, World Journal of Urology, 19(2): 141-7, 2001 April.

DiSanto, M.E., Chang, S., Hypolite, J., Zderic, S.A., Wein, AJ., Chacko, S. 2001. Enhancement of force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction. Biannual European Society for Sexual Impotence Research Meeting. International Journal of Impotence Research. 13: S40.

DiSanto, M.E., Chang, S., Hypolite, J., Zderic, S.A., Wein, A.J., Chacko, S. 2001. Alteration of corpus cavernosum smooth muscle contractility: A mechanism for diabetes-induced erectile dysfunction. Biannual European Society for Sexual Impotence Research Meeting. International Journal of Impotence Research.13: S14.

Chang, S, Hypolite, J.A., Changolkar, A., Wein, A.J., Chacko, S., DiSanto, M.E. 2001. The Mechanism of Diabetes-Induced Erectile Dysfunction Involves an Increased Sensitivity to Endothelin-1 Resulting from Overexpression of Endothelin B Receptor in the Corpus Cavernosum of the Penis. American Diabetes Association Annual Meeting. Diabetes. 50:A92.

Arafat, H.A., Sanchez-Ortiz, R.F., DiSanto, M.E., Wein, A.J., and Chacko, S. 2001. Osteopontin Overexpression in Ovariectomized Rabbit Bladder. American Urological Association Annual Meeting. Journal of Urology 165: 36A.

Zheng, Y., Weber, W.T., Wang, S., Wein, A.J., Chacko, S., and DiSanto, M.E. 2001. Establishment of a Phenotypically Stable Bladder Myocyte Cell Line from Hypertrophied Detrusor Smooth Muscle. American Urological Association Annual Meeting. Journal of Urology. 165: 38A.

Chang, S., Hypolite, J.A., Wein, A.J., Chacko, S., DiSanto, M.E. 2001. The Effect of Bladder Outlet Obstruction on Rabbit Corpus Cavernosum Smooth Muscle Contractility. American Urological Association Annual Meeting. Journal of Urology. 165:228A.

Rovner, E.S., Banner, M., Ramchandani, P., Wein, A.J.: Diagnosis and reconstruction of the circumferential urethral diverticulum. (Abstract) J. Urol. 165(5):196, 2001.

Changolkar, A.K., Hypolite, J.A., DiSanto, M.E., Chacko, S., and Wein, A.J. 2001. Induction of Free Radicals and Activation of Aldose Reductase Markers for Detrusor Contractile Dysfunction in Diabetes. American Urological Association Annual Meeting. Journal of Urology. 165: 248A.

Stein, S., Thuroff, J.W., DiSanto, M.E., Zderic, S.A., Hutcheson, J.C., Canning, D.A., Wein, A.J. and Chacko, S.K. 2001. Changes in Myosin Isoform Expression After Partial Bladder Outlet Obstruction and Reversal: Correlation with Functional Outcome in an Experimental Study. American Urological Association Annual Meeting. Journal of Urology. 165: 248A.

Arafat, H.A., Kim, G., DiSanto, M.E., Wein, A.J., and Chacko, S.K. 2001. Heterogeneity of Bladder Myocytes In Vitro: Modulation of Myosin Isoform Gene Expression. Annual Biophysical Society Meeting. Biophysical Journal. 80:388A.

Chacko, S., Changolkar, A., Kesavan, P., Arafat, H., Zheng, Y., DiSanto, M.E., Wu, H.Y., Bing, W., Zderic, S.A., and Wein, A.J. 2001. Ablation of Functional Domains in the C-terminal Region of Caldesmon in Mice by Homologous Recombination. Annual Biophysical Society Meeting. Biophysical Journal. 80:341A.

Sanchez-Ortiz, R.F., Wang, Z.E., Menon, C., DiSanto, M.E., Wein, A.J., and Chacko, S. 2001. Estrogen Modulates the Expression of Myosin Heavy Chains in Urinary Bladder Smooth Muscle. Annual Biophysical Society Meeting. Biophysical Journal. 80:575AA.

Bing, W., DiSanto, M.E., Zderic, S.A., Wein, A.J., Chacko, S. 2001. Changes in Myosin Light Chain Kinase and Phosphatase Activities in Hypertrophied Smooth Muscle. Annual Biophysical Society Meeting. Biophysical Journal. 80:389A.

Wein AJ: Nocturia in men. 1st International Consultation on Nocturia, London, England, February 22, 2002.

Wein AJ: Current thoughts about the patient with refractory overactive bladder and potential targets for new drug therapy. State of the art AUA (invited) Lecture at the European Association of Urology, Birmingham, England, February 24, 2002.

Chang, S., Velez, M., Hypolite, J.A., Changolkar, Wein, A.J., Chacko, S., DiSanto, M.E. 2002. Enhancement of the endothelin/Rho-kinase contractile pathway and decreased activity of cGMP-dependent protein kinase in corpus cavernosum smooth muscle: A possible molecular mechanism for diabetes-induced erectile dysfunction. American Society for Pharmacology and Experimental Pharmacology Ray Fuller Symposium on Lower Urinary Tract Disorders.

Hypolite, J.A., Chang, S., DiSanto, M., Zheng, Y.M., Wein, A.J., Zderic, S.A., Chacko, S. 2002. Obstruction-induced bladder hypertrophy causes alterations in the myosin isoform expression and contractility of the urethral smooth muscle. American Urological Association Annual Meeting. Journal of Urology 167: 42A.

Chang, S., Hypolite, J.A., Zderic, S.A., Wein, A.J., Chacko, S., DiSanto, M.E. 2002. Altered contractility of corpus cavernosum smooth muscle: A possible molecular basis for erectile dysfunction associated with partial bladder outlet obstruction resulting from benign prostatic hyperplasia. American Urological Association Annual Meeting. Journal of Urology 167: 236A.

Chang, S., Hypolite, J.A., Changolkar, A., Wein, A.J., Chacko, S., DiSanto, M.E. 2002. Diabetes associated erectile dysfunction: Role of endothelin and Rho-kinase. American Urological Association Annual Meeting. Journal of Urology 167: 237A.

Chang, S., Velez, M., Hypolite, J.A., Changolkar, A., Wein, A.J., Chacko, S., DiSanto, M.E. 2002. Expression and regulation of cGMP-dependent protein kinase in corpus cavernosum smooth muscle from normal and diabetic rabbits. American Urological Association Annual Meeting. Journal of Urology 167: 240A.

Bing, W., Chang, S., Hypolite, J.A., DiSanto, M., Zderic, S.A., Wein, A.J., Chacko, S. 2002. Obstruction-induced changes in detrusor contractility and alteration in myosin light chain phosphorylation: A role for Rho-kinase. American Urological Association Annual Meeting. Journal of Urology 167: 247A.

Zheng, Y.M., Weber, W.T., Wang, S., Wein, A.J., Zderic, S.A., Chacko, S., DiSanto, M.E. 2002. A smooth muscle cell line from urinary bladder that expresses SM-B myosin isoform. Annual Biophysical Society Meeting. Biophysical Journal. 82:357A.

Chang, S., Hypolite, J.A., Zderic, S.A., Wein, A.J., Chacko, S., DiSanto, M.E. 2002. Alterations in the expression of myosin isoforms and contractility in smooth muscle associated with neurological changes. Annual Biophysical Society Meeting. Biophysical Journal. 82:425A.

DAmico A, Boston MA, Whittington R, Malkowicz S, Cote K, Loffredo M, Schultz D, Ming-Hui C, Tomaszewski JE, Renshaw AA, Wein A.J., Richie JP: Biochemical outcome following radical prostatectomy or external beam radiation therapy for clinically localized prostate cancer diagnosed during the PSA era. J Urol, 167 (4):624, 2002.

Chang S, Velez M, Hypolite J, Changolkar A, Wein A.J., Chacko S, Disanto ME: Expression and Regulation of cyclic GMP-dependent protein kinase in corpus cavernosum smooth muscle from normal and diabetic rabbits. J Urology, Vol 167, 4, 941, 2002.

Chang S, Hypolite J, Wein A.J., Chacko S, Disanto ME: Altered Contractility of corpus cavernosum smooth muscle: A possible molecular basis for erectile dysfunction associated with partial bladder outlet obstruction resulting from benign prostatic hyperplasia. J Urology, Vol 167, 4, 927, 2002.

Malkowicz SB, Sanchez-Ortiz RF, Huang WC, Soyupak B, VanArsdalen K, Vaughn DJ, Wein A.J.: Favorable prognostic characteristics in node positive bladder cancer after radical cystectomy. J Urology, Vol 157, 4, 1210, 2002.

Chung BI, Burlington MA, Sanchez-Ortiz RF, Genega EM, Tomaszewski JE, VanArsdalen KN, Wein A.J.: Comparison of bladder cancer staging between academic and community hospitals. J Urology, Vol 157, 4, 1216, 2002.

Sanchez-Ortiz RF, Huang W, Van Arsdalen KN, Wein A.J., Malkowicz SB: Hydronephrosis predicts poor outcome in bladder carcinoma after radical cystectomy. J Urology, Vol 167, 4, 1219, 2002.

Sanchez-Ortiz RF, Broderick GA, Rovner ES, Wein A.J., Whittington R, Malkowicz SB: Urinary, bowel, erectile function and health-related quality of life after interstitial radiation therapy for prostate cancer. J Urology, Vol 167, 4, 1344, 2002.

Hypolite J, Chang SH, DiSanto M, Zheng YM, Wein A.J., Zderic SA, Chacko S.: Obstruction-induced bladder hypertrophy causes alterations in the myosin isoform expression and contractility of the urethral smooth muscle. J. Urol. 167:4 (suppl):42, 2002.

Chang SH, Hypolite JA, Zderic SA, Wein A.J., Chacko S.: Altered contractility of corpus cavernosum smooth muscle: a possible molecular basis for erectile dysfunction associated with partial bladder outlet obstruction resulting from benign prostatic hyperplasia. J. Urol. 167:4(suppl):236, 2002.

Editorial comments for Urologic Survey Section of the Journal of Urology; 10-15 comments in quarterly issues each year from 1987 to present.