| Shaked
A. Kidney Preservation under sub-zero temperatures.
M.D. Thesis. Hebrew University School of Medicine. May 1982.
Shaked A. Role
of Differential Class II Antigen Expression in Allo-stimulation
by Human Monocyte Hybridomas. Ph.D. Thesis. City University
of New York, July 1989.
Shaked A, Hadani
M, Reinsod M. CT and VER follow-up of reversible visual loss
with fracture of the optic canal. Acta Neurochirurigca 1982;
62: 91-94.
Gomori JM, Shaked A.
Radiation-induced meningiomas. Neuroradiology 1982; 23: 211-212.
Shaked A. Shinar
E, Freund H. Neutropenic typhlitis: a plea for conservatism.
Dis Colon Rectum 1983; 26: 351-352.
Shaked A, Raz
E, Romanov H. Asymptomatic highly vascularized superior mediastinal
mass. Chest 1984; 86: 621-622.
Katz LB, Shaked A,
Messer J. Colonic varices hemorrhage: Diagnosis and management.
J Clin Gastroenterology. 1985; 7: 67-69.
Shaked A, Meretyk
S, Pode D, Caine M. Nontraumatic spontaneous rupture of the
urinary bladder. Can J Surg 1986; 29 107-109.
Shaked A, Shinar
E, Freund H. Managing the neutropenic patient with acute perianal
inflammation. Am J Surg 1986; 152: 510-512.
Gordon RE, Shaked A,
Solano P. Taurine protects hamster bronchioles from acute
NO2-induced alterations: a histologic, ultrastructure and
freeze fracture study. Am J Pathol 1986; 125 585-600.
Shaked A, Sherris
D, Mayer L. Isolation of fibroblast proliferation factor:
Distinction from interleukin I. Current Surgery 1987; 44:
487-490.
Shaked A, Mayer
L. Recognition of class II or non MHC allodeterminants by
T. cells using human monocyte hybridomas. Transplant Proc
1988; 20, (no. 1, Suppl. 1): 267-268.
Shaked A. Busuttil
RW. Auxiliary liver transplantation: a negative view point.
Hepatology 1990; 12: 173.
Sperber K, Shaked A,
Posnet D, Hirschman S, Bekesi G, Mayer L, Surface expression
of CD4 does not predict susceptibility to infection with HIV-1
In monocytic cells. J Clin Lab. Immunol 1990; 4: 151-156.
Shaked A, Busuttil
RW, Sher L, Makowka L. Diagnosis and treatment of early rejection
in liver transplantation. Transplantation Sci 1991; 1: 18-23.
Binderow S, Shaked A.
Acute appendicitis in patients with HIV+AIDS infection. Am
J Surg 1991; 162: 9-12.
Shaked A, Larrick
J, Fotino M, Mayer L. Generation and characterization of human
monocyte hybridomas. J. Immunol Methods 1991; 140: 45-55.
Shaked A, Calderon
I, Durst A. Safety of surgical procedures performed by residents.
Arch Surg 1991; 126: 559-560.
Shaked A, Takiff
H, Busuttil RW. The use of the supraceliac aorta for hepatic
artery revascularization in liver transplantation. Surg Gynecol
Obstet 1991; 173:198-202.
Shaked A, Sperber
K, Mayer FL. Stimulation of distinct T cells in MLR using
human macrophage hybridomas differentially expressing class
II antigens. Transplantation 1991; 52:1068-1072.
Shaked A, Busuttil
RW. Liver transplantation in patients with portal vein thrombosis
and central portacaval shunts. Ann Surg 1991; 214: 696-702.
Sue P, Wilkinson A, Shaked
A, Busuttil RW. Hepatorenal syndrome in liver transplantation.
Am Surg 1991; 57: 806-809.
Brunicardi FC, Watt PC, Colonna
JO, Gelabert H, Shaked A, Gingerich R. Paracrine
regulation of islet cell secretion in the isolated perfused
human pancreas. Surg Forum 1991; XLII: 165-167.
Shaked A, McDiarmid
S, Harrison R, Busuttil RW. Gas gangrene of the liver following
orthotopic liver transplantation. Surgery 1992; 4: 462-465.
Canfield CW, Hudnall SD, Colonna
JO, Busuttil RW, Wilkinson AH, Danovitch G, Shaked
A, Goldstein L, Rosenthal JT. Fulminant EBV associated
lymphoproliferative disorders following OKT3 therapy. Clin
Transpl 1992; 6:1-9.
Shaked A, Goldstein
R, Klintmalm G, Drazan K, Husberg J, Busuttil RW. Portosystemic
shunt versus orthotopic liver transplantation for the Budd-Chiari
syndrome. Surg Gynecol Obstet 1992; 174:453-459.
Shaked A, Hoyos
B, Mayer L. The role of differential class II antigen expression
in stimulation of allo-geneic mixed lymphocyte reactions by
human monocyte hybridomas. Transplantation 1992; 53:1341-1347.
Shaked A, Colonna
JO, Goldstein L, Busuttil RW. The interrelation between sclerosing
cholangitis and ulcerative colitis in patients undergoing
liver transplantation. Ann Surg 1992; 215:598-605.
Konishi K, Shaked A,
Egawa H, Ozawa K, Busuttil RW. Correlation of hepatic injury
synthetic func-tion and mitochondria energy level in orthotopic
liver transplantation. J Surg Res 1992; 52:466-571.
Takiff H, Shaked A,
Francis DJ, Busuttil RW. Cystic neoplasm of the liver: lessons
in management. Digestive Surgery 1992; 9:166-168.
Colonna JO, Shaked A,
Gomes AS, Colquhoun SD, Jurim O, McDiarmid SV, Millis MJ,
Goldstein LI, Busuttil RW. Biliary strictures complicating
liver transplantation: Incidence, pathogenesis, management.
Ann Surg 1992; 216:344-352.
Umeshita K, Monden M, Tono T,
Hasuike Y, Kanai T, Gotoh M, Mori T, Seu P, Shaked
A, Busuttil RW. Interleukin 6 (IL-6) in bile as a
marker of allograft rejection following liver transplantation
in man. Transplant Proc 1992; 24:1462-1464.
Colonna JO, Shaked A,
Gelabert HA, Busuttil RW. Resection of the caudate lobe through
the "bloody gulch". Surg Gynecol Obset 1993; 176:401-402.
Busuttil RW, Farmer DG, Shaked
A, Rolandelli R, Colonna JO, Jurim O, Colquhoun SD,
Bertstein C, Shanahan F, Robert M, Goldstein LI, McDiarmid
SV. Successful combined liver and small intestine transplantation
for short gut syndrome and liver failure. West J Med 1993;
158:184-188.
Egawa H, Shaked A,
Konishi Y, McDiarmid SV, Vargas JH, Shimahara Y, Colonna JO,
Yamamoto N, Ozawa K, Busuttil RW. Arterial ketone body ratio
in pediatric liver transplantation. Transplantation 1993;
55:522-526.
McDiarmid SV, Colonna JO, Shaked
A, Vargas J, Ament ME, Busuttil RW. Differences in
oral FK506 dose requirements between adult and pediatric liver
transplant patients. Transplantation 1993; 55:1328-1332.
Shiraishi M, Shaked A,
Imagawa D. Farmer D, Hasuike Y, Busuttil RW. Monoclonal anti-tumor
necrosis factor alpha (TNF?) antibody suppresses rejection,
but enhances infectious complications in rat liver allograft
recipients. Transplant Proc 1993; 25(1):128-129.
Farmer DG, McDiarmid SV, Kuniyoshi
J, Robert ME, Shaked A, Busuttil RW. Intragraft
expression of interleukin-2 and interferon-Gamma messenger
RNA is a predictor of rejection in rat small intestine allografts.
American College of Surgeons Surgical Forum Volume XLIV, proceedings
of the 79th Annual Clinical Congress, October 1993, San Francisco,
California. 1993; XLIV:426-428.
Shaked A, Thompson
M, Wilkinson AH, Nuesse B, El-Khoury GF, Rosenthal JT, Danovitch
GM, Busuttil RW. The role of combined liver/kidney transplantation
in end-stage hepato-renal disease. Am Surg 1993; 59:605-609.
Colquhoun S, Shaked A,
Jurim O, Colonna JO, Rosove M, Busuttil RW. Reversal of neutropenia
with granulocyte colony-stimulating factor without precipitating
liver allograft rejection. Transplantation 1993; 56:755-758.
Jurim O, Shaked A,
Kiai K, Millis JM, Colquhoun SD, Busuttil RW. Celiac compression
syndrome and liver transplantation. Ann Surg 1993; 218:10-12.
Sherman S, Shaked A,
Cryer HM, Goldstein LI, Busuttil RW. Endoscopic management
of biliary fistulas complicating liver transplantation and
other hepatobiliary operations. Ann Surg 1993; 218:167-175.
McDiarmid SV, Colonna JO, Shaked
A, Ament M, Busuttil RW. A comparison of renal function
in cyclosporine-and FK-506-treated patients after primary
orthotopic liver transplantation. Transplantation 1993; 56:847-853.
Farmer DG, Shaked A,
Colonna JO, Olthoff KM, Jurim O, Colquhoun S, Millis JM, Busuttil
RW. Radical resection combined with liver transplantation
for foregut tumors. Am Surg 1993; 59:806-812.
Csete ME, Neelakanta G, Shaked
A, Busuttil RW. Prolonged venovenous bypass for intraoperative
failure of transplanted livers: A report of three cases. Transplantation
1993; 56:1290-291.
Shaked A, Vargas
J, Csete ME, Kiai K, Jurim O, Colquhoun S, McDiarmid SV, Ament
ME, Busuttil RW. Diagnosis and treatment of bowel perforation
following pediatric orthotopic liver transplantation. Arch
Surg 1993; 128:994-999.
Hasuike Y, Shaked A,
Shiraishi M, Farmer D, Busuttil RW. Selective mesenteric lymphoid
irradi-ation eliminates the effector cells of lethal graft
vs. host disease, while protecting the radiosensitive intestinal
tissue. Transplant Proc 1993; 25(1):1196-1197.
Colquhoun S, Shaked
A, Jurim O, Colonna JO, Rosove M, Busuttil RW. Reversal
of neutropenia with granulocyte colony-stimulating factor
without precipitating liver allograft rejection. Transplantation.
1993; 56:1593-1595.
Jurim O, Colonna JO, Colquhoun
SD, Shaked A, Busuttil RW. A stapling technique
for liver resection. J Am College Surg 1994; 178:510-511.
Shaked A, Csete
ME, Shiraishi M, Miller AR, Moen RC, Busuttil RW, Economou
JS. Retroviral-mediated gene transfer into rat experimental
liver transplant. Transplantation 1994; 57:32-34.
Farmer DF, Rosove MH, Shaked
A, Busuttil RW. Current treatment modalities for
hepatocellular carcinoma: A review. Ann Surg 1994; 236-247.
Shiraishi M, Csete ME, Yasunaga
C, Drazan KE, Jurim O, Cramer DV, Busuttil RW, Shaked
A. Regeneration-induced accelerated rejection in
reduced-size liver grafts. Transplantation 1994; 57:336-340.
Karademir S, Csete ME, Shaked
A, Finstead T, Hawkins R, Busuttil RW. The role of
99mT labeled DISIDA scan in the assessment of marginal liver
grafts after orthotopic liver transplantation. Clin Transplant
1994; 8:54-58.
Colquhoun SD, Robert ME, Shaked
A, Rosenthal JT, Millis JM, Jurim O, Busuttil RW.
Transmission of CNS malignancy by organ transplantation. Transplantation
1994; 57:970-974.
Busuttil RW, Shaked A,
Colquhoun SD, Jurim O, Millis JM, Nuesse BJ, Csete ME, Goldstein
LI, McDiarmid SV. One thousand liver transplants: The lessons
learned. Ann Surg 1994; 219: 490-499.
Csete ME, Drazan KE, van Bree
M, McIntee DF, McBride WH, Bett A, Graham FL, Busuttil RW,
Berk AJ, Shaked A. Adenovirus-mediated gene
transfer in the transplant setting. Part I: Conditions for
expression of transferred genes in cold preserved hepatocytes.
Transplantation 1994; 57: 1502-1507.
Shaked A, Csete
ME, Drazan KE, Wu L, Busuttil RW, Berk AJ. Adenovirus-mediated
gene transfer in the transplant setting. Part II: Successful
expression of transferred cDNA in syngeneic liver grafts.
Transplantation 1994; 57:1508-1511.
Jurim O, Martin P, Shaked
A, Busuttil RW. Liver transplantation for chronic
hepatitis B in Asians. Transplantation 1994; 57: 1393-1395.
Jurim O, Shaked A,
Rose S, Busuttil RW. Volvulus of the Roux-en-y hepatico-jejunostomy:
a rare complication manifested by recurrent ascending cholangitis.
International Surgery 1994; 79: 176-177.
Drazan KE, Shen XD, Csete ME,
Zhang WW, Roth JA, Busuttil RW, Shaked A.
In vivo adenoviral-mediated human p53 tumor suppressor gene
transfer and expression in rat liver following resection.
Surgery 1994; 8:197-203.
Morris, Jr. BD, Drazan KE, Csete
ME, van Bree MP, Rosenthal JT, Shaked A.
Adenoviral-mediated gene transfer to bladder in vivo. J of
Urology 1994; 152:506-509.
Lo CM, Shaked A,
Busuttil RW. Risk factors for liver transplantation across
ABO barrier. Transplantation 1994; 58:543-547.
Farmer DG, McDiarmid SV, Kuniyoshi
J, Robert ME, Shaked A, Busuttil RW. Intragraft
expression of messenger RNA for interleukin-6 and tumor necrosis
factor-alpha are predictors of rat small intestine transplant
rejection. J Surg Res 1994; 57: 138-142.
Csete ME, Afra R, Mullen Y, Drazan
KE, Benhamou PY, Shaked A. Adenoviral-mediated
gene transfer to pancreatic islets does not alter islet function.
Transplant Proc 1994; 26: 756-757.
Jurim O, Gelabert HA, Shaked
A, Nuesse BJ, McDiarmid SV, Busuttil RW. Reduced
graft OLT for emergency indications in pediatric patients.
Transplant Proc 1994; 26:195.
McDiarmid SV, Farmer DG, Kuniyoshi
JS, Robert M, Khadavi A, Shaked A, Busuttil
RW. Intragraft cytokine and cytotoxic T lymphocyte (CTL) specific
protein expression are predictors of rat small intestine transplant
rejection. Transplant Proc 1994; 26: 1520-1521.
Drazan KE, Csete ME, Shen XD,
Busuttil RW, Berk A, Shaked A. Hepatic liver
function is preserved after adenoviral-mediated gene transfer.
J Surg Res 1995; 59:299-304.
McDiarmid SV, Farmer DG, Kuniyoshi
JS, Robert M, Khadavi A, Shaked A, Busuttil
RW. The correlation of intragraft cytokine expression with
rejection in rat small intestine transplantation. Transplantation
1994; 58:690-697.
Badie B, Drazan KE, Shaked
A, Black K. Adenoviral-mediated p53 gene delivery
induces cell death in cultured 9L glioma cells. Neurological
Science 1994; (In press).
Shiraishi M, Prager MC, Yasunaga
C, McDiarmid SV, Vannice JL, Busuttil RW, Shaked A.
The inhibitor cytokine IL-1 receptor antagonist, synergistically
augments cyclosporine immunosuppression in a rat cardiac allograft
model. J Surg Research 1995; 58:465-470.
Jurim O, Shaked A.
Reduced-size grafts -- The solution for hepatic artery thrombosis
after pediatric liver transplantation? J Ped Surg 1995; 30:53-55.
Csete ME, Drazan KE, Benhamou
PY, Shen XD, McIntee DF, Afra R, Mullen Y, Shaked
A. Efficient gene transfer to pancreatic islet mediated
by adenoviral vectors. Transplantation 1995; 59:763-768.
Drazan KE, Shen XD, Busuttil
RW, Csete M, Shaked A. Gene transfer in the
transplant setting III: Variables affecting recombinant gene
expression in liver grafts. Transplantation 1995; 59:670-673.
McDiarmid SV, Farmer DG, Kuniyoshi
JS, Robert M, Khadavi A, Shaked A, Busuttil
RW. Perforin and granzyme B: Cytolytic proteins up regulated
during rejection of rat small intestine allgorafts. Transplantation.
1995; 59:762-766.
Badie B, Drazan KE, Kramar MH,
Shaked A, Black KL. Adenovirus-mediated gene
delivery inhibits 9L glioma growth in rats. Neurol Res 1995;
17:209-216.
Lo CM, Shaked A,
Drazan K, Yersiz H, Jurim O, Busuttil RW. Variables affecting
transplantation across ABO blood groups. Transplant Proc 1995;
27:1159.
Drazan KE, Shen XD, Wu L, Jurim
O, Busuttil RW, Shaked A. Adenoviral-mediated
gene transfer to liver xenografts results in successful expression
and protein production. Transplant Proc 1995; 27:331-332.
Qin L, Chavin KD, Ding Y, Favaro
JP, Woodward JE, Lin J, Tahara H, Robbins P, Shaked
A, Ho D, Sapolsky R, Bromberg JS. Multiple vectors
effectively achieve gene transfer in a murine cardiac transplantation
model. Transplantation 1995; 59:809-816.
Millis JM, Imagawa DK, Olthoff
KM, Martin P, Gomes A, Shaked A, Yersiz H,
Drazan K, Jurim O, Goldstein LI, Busuttil RW. T.I.P.S.: Impact
on liver transplantation. Transplant Proc 1995; 27:1252-1253.
Farmer DG, Shaked A,
Olthoff KM, Imagawa DK, Millis JM, Busuttil RW. Evaluation,
operative management and outcome after liver transplantation
in children with biliary atresia and situs inversus. Ann Surg
1995; 222:47-50.
Drazan KE, Wu L, Olthoff KM,
Jurim O, Busuttil RW, Shaked A. Transduction
of hepatic allografts achieves local levels of viral IL-10
which suppress alloreactivity in vitro. J Surg Res 1995; 59:219-223.
Olthoff KM, Rosove MH, Imagawa
DK, Shackleton CR, Farmer D, Martin P, Goldstein LI, Shaked
A, Busuttil RW. Adjuvant chemotherapy improves survival
following liver transplantation for hepatocellular carcinoma.
Ann Surg 1995; 221:734-741.
Shackleton CR, Jurim O, McDiarmid
SV, Martin P, Shaked A, Maxfield A, Pakrasi
AL, Melinek J, Ament M, Vargas J, Millis JM, Imagawa DK, Olthoff
KM, Goldstein LI, Busuttil RW. Living donor liver transplantation:
Potential treatment of choice for pediatric recipients. Am
J Surgery 1995; 169:529-532.
Winston D, Wirin D, Shaked
A, Busuttil RW. Long-term cytomegalovirus prophylaxis
in liver transplant recipients: A randomized comparison of
ganciclovir and high-dose acyclovir. Lancet 1995; 346(8967):67-74.
Farmer DG. Shaked A.
McDiarmid SV. Olthoff KM. Millis JM. Imagawa DK. Colonna JO.
Robert ME. Lewin K. Goldstein LI. Busuttil RW. Small intestine
transplantation at the University of California, Los Angeles.
Transplant Proc 1996; 28: 2746-2747.
Shackleton C, Martin P, Melinek
J, Stothers L, Millis JM, Olthoff KM, Imagawa DK, Kinkhabwala
M, Rudich S, Seu P, Shaked A, McDiarmid SV,
Goldstein LI, Busuttil RW. Lack of correlation between the
magnitude of preservation injury and the incidence of acute
rejection, need for OKT3 or conversion to FK506 in cyclosporine
treated primary liver allograft recipients. Transplantation
1995; 60:554-558.
Yersiz H, Shaked A,
Olthoff KM, Imagawa DK, Shackleton C, Martin P, Busuttil RW.
Correlation between donor age and the pattern of liver graft
recovery after transplantation. Transplantation 1995; 60:790-794.
Sherman S, Jamidar P, Shaked
A, Kendall B, Goldstein L, Busuttil RW. Biliary tract
complications after orthotopic liver transplantation: Endoscopic
approach to diagnosis and therapy. Transplantation 1995; 60:467-470.
Jurim O, Shackleton CR, McDiarmid
SV, Martin P, Shaked A, Millis JM, Imagawa
DK, Olthoff KM, Maxfield A, Pakrasi AL, Melinek J, Ament M,
Vargas J, Goldstein LI, Busuttil RW. Living-Donor Liver Transplantation
at UCLA. Am J Surg 1995; 169:529-532.
Winston DJ, Imagawa DK, Holt
CD, Kaldas F, Shaked A, Busuttil RW. Long-term
ganciclovir prophylaxis eliminates serious cytomegalovirus
disease in liver transplant recipients receiving OKT3 therapy
for rejection. Transplantation 1995; 60:1357-1360.
Seu P, Olthoff KM, Rudich S,
Kinkhabwala M, Imagawa DK, Neelankanta G, Goldstein LI, Martin
P, Shackleton CR, Shaked A, Busuttil RW.
Liver transplantation for fulminant hepatic failure in a Jehovah’s
witness. Clin Transplant 1996; 10:404-407.
Imagawa DK, Olthoff KM, Hasan
Y, Shackleton CR, Colquhoun SD, Shaked A,
Busuttil RW. Rapid en bloc technique for pancreas-liver procurement.
Transplantation 1996; 61:1605-1609.
Farmer DG, Shaked A,
McDiarmid SV, Olthoff KM, Imagawa DK, Millis JM, Robert ME,
Lewin K, Goldstein LI, Busuttil RW. Small intestine transplantation:
The University of California Los Angeles Experience. Transplant
Proc 1996;28:2746-47.
Imagawa, DK, Olthoff KM, Yersiz
H, Shackleton CR, Colquhoun SD, Shaked A,
Busuttil RW. Rapid en bloc technique for pancreas-liver procurement:
Improved early liver function. Transplantation 1996;28:2746-2747.
Umeshita K, Monden M, Tono T,
Hasuike Y, Kanai T, Gotoh M, Mori T, Shaked A,
Busuttil RW. Determination of the presence of interleukin-6
in bile after orthotopic liver transplantation: Its role in
the diagnosis of acute rejection. Ann Surg 1996; 223:204-211.
Werthman PE, Drazan KE, Rosenthal
JT, Shalili R, Shaked A. Adenoviral-p53 gene
transfer to orthotopic and peritoneal murine bladder cancer.
J Urol 1996; 155(2):753-756.
Dawson S 3rd, Imagawa DK, Cecka
JM, Gjertson DW, Shackleton CM, Shaked A,
Busuttil R. UCLA liver transplantation: analysis of the first
1,000 patients. Clin Transplant 1994;189-195.
Drazan KE, Wu L, Olthoff KM,
Shen XD, Gelman A, Shaked A. Adenovirus-mediated
gene transfer in the transplant setting: Early events after
orthotopic transplantation of liver allografts expressing
TGF- ?1. Transplantation 1996; 62:1080-1084.
Drazan KE, Hebebrand D, Shaked
A, Jones NF. Gene transfer during limb replantation.
J Reconstr Microsurg 1997;13:383-387.
Jurim O, Martin P, Winston DJ,
Shackleton C, Holt C, Feller J, Csete M, Shaked A,
Imagawa D, Olthoff KM, Lau JYN, Busuttil RW. Failure of ganciclovir
prophylaxis to prevent allograft reinfection following orthotopic
liver transplantation for chronic hepatitis B infection. Liver
Transplant Surg 1996;2:370-374.
Seu P, Shackleton CR, Shaked
A, Imagawa DK, Olthoff KM, Rudich ST, Kinkhabwala
J, Busuttil RW. Improved results of liver transplantation
in patients with portal vein thrombosis. Arch Surg 1996;131:840-845.
Millis M, Melinek J, Csete M,
Imagawa DK, Olthoff KM, Neelankanta G, Braunfeld MYC, Sopher
MJ, Chan SM, Pregler JL, Yersiz H, Busuttil AA, Shackleton
CR, Shaked A, Busuttil RW. Randomized controlled
trial to evaluate flush and reperfusion techniques in liver
transplantation. Transplantation 1997;63:397-403.
Drazan KE, Shaked A,
Olthoff KM, Imagawa D, Jurim O, Kiai K, Shackleton C, Busuttil
RW. Etiology and management of adult hepatic artery thrombosis
after orthotopic liver transplantation. Am Surg 1996;62:237-240.
Drazan KE, Wu L, Bullington D,
Shaked A. Viral IL-10 gene therapy inhibits
TNF-alpha and IL-1beta, not IL-6 in the newborn endotoxemic
mouse. J Ped Surg 1996; 31:411-414.
Benhamou PY, Mullen Y, Shaked
A, Bahmiller D, Csete M: Decreased alloreactivity
to human islets secreting recombinant viral interleukin-10.
Transplantation 1996;62:1306-1312.
Weber M, Deng S, Kucher T, Shaked
A, Ketchum, Brayman K: Adenoviral transfection of
isolated pancreatic islets: A study of programmed cell death
(Apoptosis) and islet function. J Surg Res:1997;69:23-32.
Olthoff KM. Rosove MH. Shackleton
CR. Imagawa DK. Farmer DG. Northcross P. Pakrasi AL. Martin
P. Goldstein LI. Shaked A. Busuttil RW. Continuous
infusional 5-fluorouracil chemotherapy. Ann Surg 1996; 224:
686.
Deng S. Ketchum RJ. Yang ZD.
Kucher T. Weber M. Shaked A. Naji A. Brayman
KL. IL-10 and TGF-beta gene transfer to rodent islets: effect
on xenogeneic islet graft survival in naive and B-cell-deficient
mice. Transplant Proc 1997; 29: 2207-2208.
Deng S. Yang ZD. Ketchum RJ.
Kucher T. Weber M. Shaked A. Naji A. Brayman
KL. Transfer of genes for IL-10 and TGF-beta to isolated human
pancreatic islets. Transplant Proc 1997; 29: 2206.
Deng S. Ketchum RJ. Kucher T.
Weber M. Shaked A. Naji A. Brayman KL. IL-10
and TGF-beta gene transfer for xenogeneic islet transplantation:
comparison of effect in concordant vs discordant combination.
Transplant Proc 1997; 29: 2204-2205.
Holt CD. Winston DJ. Kubak B.
Imagawa DK. Martin P. Goldstein L. Olthoff K. Millis JM. Shaked
A. Shackleton CR. Busuttil RW. Coccidioidomycosis
in liver transplant patients. Clin Infect Dis 1997; 24: 216-221.
Weber M. Deng S. Kucher T. Shaked
A. Ketchum RJ. Brayman KL. Increased DNA fragmentation
in isolated rat islets following 24 hour co-culture with cytokine
transgene-bearing adenovirus is dose dependent, but does not
reduce glucose-stimulated insulin secretion. Transplant Proc
1997; 29: 1728-1729.
Olthoff KM. Da Shen X. Gelman
A. Turka L. Shaked A. Adenovirus-mediated
gene transfer of CTLA4Ig to liver allografts results in prolonged
survival and local T-cell anergy. Transplant Proc 1997; 29:
1030-1031.
Shaked A. Olthoff
K. Sellers M. Chen XD. Gelman A. Tolerance to a second donor-matched
allograft following local immune modulation using transfer
of sequences encoding CTLA4Ig. Transplan Proc 1997; 29: 1026.
Deng S. Ketchum RJ. Kucher T.
Weber M. Shaked A. Naji A. Brayman KL. Denoviral
transfec-tion of canine islet xenografts with immunosuppressive
cytokine genes abrogates primary non-function and prolongs
graft survival. Transplant Proc 1997; 29: 770.
Sellers M. Singer A. Maller E.
Olthoff K. Jacobowski D. Shaked A. Incidence
of late acute rejection and progression to chronic rejection
in pediatric liver recipients. Transplant Proc. 1997; 29:
428-9.
Shaked A: The
use of T tube in liver transplantation. Liver Transplant Surg
1997;3:S22-S23.
Shaked A, Nunes
FA, Olthoff KM, Lucey MR: Assessment of liver function: Pre-and
peri-transplant evaluation. Clin Chem:1997;43:8:1539-545.
Qin L, Ding, Y, Pahud, DR, Robson
ND, Shaked A, Bromberg JS: Adenovirus-mediated
gene transfer of viral interleukin-10 inhibits the immune
response to both alloantigen and adenoviral antigen. Hum Gene
Ther:1997;8:1365-1374.
Weber M, Deng S, Olthoff K, Naji
A, Barker CF, Shaked A, Brayman KL. Organ
transplantation towards the twenty first century. Uro Clin
North Am 1998;25:51-61.
Cherukuri R, Haskal ZJ, Shaked
A. Percutaneous thrombolysis and stent placement
for the treat-ment of portal vein thrombosis after liver transplantation:
Long term follow-up. Transplantation 1998; 65:1124-1126.
Olthoff KM, Judge TA, Gelman
A, Shen X, Hancock WW, Linsley PS, Turka LA, Shaked
A. Adenovirus-mediated gene transfer into cold-preserved
liver allografts: Survival pattern and tolerance following
transduction with CTLA4Ig. Nat Med 1998;4:194-200.
Rosengard BR, Shaked
A. Persistence of donor antigen is necessary for
maintenance of xenotolerance—a parallel to allogeneic
systems. Transplantation 1999;68(8):1095-1096.
Liu C, Deng S, Yang Z, Kucher
T, Guo F, Gelman A, Chen H, Naji, Shaked A,
Brayman KL. Local production of CTLA4-Ig by adenoviral-mediated
gene transfer to the pancreas induces permanent allograft
survival and donor-specific tolerance. Transplant Proc 1999;31:625-626.
Marcucci L, Shaked A,
Maller ES, Rand EB, Hahn ES, Higuchi NH, Barker CF, Olthoff
KM. Supraceliac aortic pseudoaneurysms following liver transplantation
in infants. Transplantation 1999;68(10):1617-1619.
Zamir G, Olthoff K, Nunes F,
Markmann J, Zeldin G, Stewart C, Weinreib R, Rand E, Maller
E, Lucey M, Shaked A. Liver transplantation
at the University of Pennsylvania and the Children’s
Hospital of Philadelphia. Clin Transplant 1999;223:229.
Zamir GA, Markmann, JF, Abrams
J, Macatee MR, Nunes FA, Shaked A, Olthoff
KM. The fate of liver grafts declined for subjective reasons
and transplanted out of a local procurement organization.
Transplantation 2000;70(8):1149-1154.
Pfau PR, Kochman ML, Long WB,
Lewis JD, Lucey MR, Olthoff K, Shaked A,
Ginsberg GG. Endoscopic management of postoperative biliary
complication in orthotopic liver transplantation. Gastrointest
Endosc 2000;52(1):55-63.
Porter D, Shaked A.
Exploring the potential for graft vs. tumor response in a
combine bone marrow and liver transplantation for large hepatocellular
carcinoma. Transplantation 2000;69(10):2003-2004.
Venkataramanan R, Shaw LM, Sarkozi
L, Mullins R, Pirsch J, MacFarlane G, Scheller D, Ersfeld,
Frick M, Fitzsimmons WE, Virgi M, Jain A, Brayman KL, Shaked
A. Clinical utility of monitoring tacrolimus blood
concentrations in liver transplant patients. J Clin Pharm
2001;41(5):542-51.
Velidedeoglu E, Desai NM, Campos
L, Olthoff KM, Shaked A, Nunes F, Zeldin
G, Stewart C, Blumberg E, Abrams J, Markmann JF. Effect of
donor hepatitis C on liver graft survival. Transplantation
Proceedings 2001;33:3795-3976.
Olthoff KM, Gelman AE, Zamir
GA, Debonera F, Krasinkas AM, Shen X, Gao F, Shaked
A. Pattern of alloimmune response in second same
donor allografts after induction of tolerance using CTLA4Ig.
Transplantation 2001;Dec 27:72(12):1952-1956.
Zamir G, Olthoff KM, Desai N,
Markmann JF, Shaked A. Toward further expansion
for organ pool for adult liver recipients-splitting the cadaveric
liver into right and left lobes. Transplantation 2002;74(12):1757-1761.
Liu C, Deng S, Jiang K, Gelman
A, Shaked A, Brayman KL. Mechanism of adenoviral-
mediated CTLA4-IG gene-induced pancreatic allograft tolerance
in rats. Trans Proc 2001; 33(1-2) 134.
Liu C, Jiang K, Deng S, Gelman
A, Shaked A, Brayman K. Long-term localized
transgene expres-sion in the pancreas achieved by intra-arterial
adenoassociated virus-mediated gene transfer. Trans Proc 2001;33:603.
Shaked A, Lucey
MR. Transplantation of liver grafts from living donors into
adults. New Eng J Med 2001;345(12):923-924.
Singer AL, Olthoff KM, Kim H,
Rand E, Zamir G, Shaked A. The role of plasmapheresis
in the management of acute hepatic failure in the pediatric
population. Ann Surg 2001;234(3):418-424.
Zamir G, Gelman A, Debonera F,
Hardwigsen J, Que X, Aldeguer X, Martin M, Shaked
A, Olthoff K. Modified AdCTLA-4 vector blocks alloimmune
response in-vitro. J Surg Res 2001, 97:155-158.
Markmann JF, Shaked A.
Immunomodulation by intrathymic injection of donor leukocytes
in rhesus monkeys. Transplantation 2001;72(8):1351-1352
140. Shaked A. Splitting the cadaveric liver into the right
and left lobes for two adult recipients. Liver Transplant
2002;8:82-84.
Aldeguer A, Debonera F, Shaked
A, Krasinkas AM, Gelman AD, Que X, Zamir GA, Hiroyasu
S, Kovalovich KK, Taub R, Olthoff KM. Interleukin-6 from intrahepatic
cells of bone marrow origin is required for normal murine
liver regeneration. Hepatology 2002;35(1):40-48.
Velidedeoglu E, Desai NJ, Campos
L, Olthoff KM, Shaked A, Nunes F, Zeldin
G, Stewart C, Blumberg E, Abrams J, Markmann JF. The outcome
of liver grafts procured from hepatitis C-positive donor Transplantation
2002;73:582-587.
Abt P, Crawford M, Desai N, Markmann
J, Olthoff K, Shaked A. Liver transplantation
from controlled non-heart beating donors: An increased incidence
of biliary complications. Transplantation 2003;75(10):1659-1663.
Shah JN, Haigh WG, Lee SP, Lucey
MR, Brensinger C, Kochman ML, Long WB, Olthoff K, Shaked
A, Ginsberg GG. Biliary casts following adult orthotopic
liver transplantation: Clinical factors, treatment, and biochemical
analysis. Amer J Gastroenterol 2003;98:1861-1867.
Debonera F, Krasinkas AM, Gelman
AE, Aldeguer X, Que X, Shaked A, Olthoff
KM. Dexamethasone inhibits early regenerative response of
rat liver after cold preservation and transplantation. Hepatology
2003;38:1563-1572.
Krasinskas AM, Minda J, Saul
SH, Shaked A, Furth EE. Redistribution of
thorotrast into a liver allograft several years following
transplantation: a case report. Mod Pathol 2004;17:117-120.
Htaik TT, Santaniello NA, Markmann
JF, Shaked A, Clark TW. Treatment of obstructive
ephro-ureteral clot with a rheolytic mechanical thrombectomy
device. J Vasc Interv Radiol. 2003;14(7):933-936.
Abt PL, Mange KC, Olthoff KM,
Markmann JF, Reddy KR, Shaked A. Allograft
survival follow-ing adult to adult living donor liver transplantation
Am J of Transplantation 2004;4(8):1302-1307.
Shah JN, Ahmad NA, Shetty K,
Kochman ML, Long WB, Brensinger CM, Pfau PR, Olthoff K, Markmann
J, Shaked A, Reddy R, Ginsberg GG. Biliary
complications after adult living donor liver transplantation:
Type, endoscopic management, and comparison to cadaveric transplantation.
Am J of Gastroenterology 2004;99(7):1291-1295.
Shetty K, Timmins K, Brensinger
C, Furth EE, Rattan S, Sun W, Rosen M, Shaked A,
Reddy KR, Olthoff KM. Liver transplantation for hepatocellular
carcinoma validation of present selection criteria in predicting
outcome. Liver Transpl. 2004;10(7):911-918.
Stewart CA, Wertheim J, Olthoff
K, Furth EE, Brensinger C, Markman J, Shaked A.
Ascites after liver transplantation – A mystery. Liver
Transpl 2004;10(5):654-660.
Velidedeoglu E, Bloom RD, Crawford
MD, Desai NM, Campos L, Apt P, Markmann JW, Mange KC, Olthoff
KM, Shaked A, Markmann JF. Early kidney dysfunction
post liver transplantation predicts late chronic kidney disease.
Transplantation 2004;77(4):553-556.
Shah JN, Ahmad NA, Shetty K,
Kochman ML, Long WB, Brensinger CM, Pfau PR, Olthoff K, Markmann
J, Shaked A, Reddy KR, Ginsberg GG. Endoscopic
management of biliary complications after adult living donor
liver transplantation. Am J Gastroenterol 2004 Jul;99(7):1291-1295.
Abt PL, Rapaport-Kelz R, Desai
N, Frank A, Sonnad S, Rand E, Markmann JF, Shaked
A, Olthoff KM. Survival among pediatric liver transplant
recipients: Impact of segmental grafts. Liver Transpl 2004;10(10):1287.
Debonera F, Wang G, Xie J, Que
X, Gelman A, Leclair C, Xin D, Shaked A,
Olthoff KM. Severe Preservation Injury Induces Il-6/STAT3
activation with lack of cell cycle progression after partial
liver graft transplantation. Am J Transplant 2004 Dec;4(12):1964-71.
Zamir G, Gelman AE, Olthoff KM,
Debonera F, Aldeguer X, Shaked A. Patterns
of transgene expression and viral clearance from the transplanted
liver following ex vivo adenovirus-mediated gene transfer.
J Hepatol 2004;41(5):714-20.
Olthoff KM, Brown RS Jr, Delmonico
FL, Freeman RB, McDiarmid SV, Merion RM, Millis JM, Roberts
JP, Shaked A, Wiesner RH, Lucey MR. Summary
report of a national conference: Evolving concepts in liver
allocation in the MELD and PELD era. Liver Transpl 2004 Oct;10
Suppl 10:A6-A22.
Blonski W, Reddy R, Shaked
A, Siegelman E, Metz D. Liver Transplantation for
metastatic neuroendocrine tumor; a case report and review
of the literature. Liver Transpl 2004 (submitted).
Research Publications, Non-Peer Reviewed
Abt P, Shaked A.
The Allograft Immune Response. Graft 2003;6(2)71-79.
Crawford M, Shaked A.
The liver transplant operation. Graft 2003;6(2):98-109.
Abstracts: (last three years)
Crawford MD, Desai NM, Foreman
LM, Timmons KJ, Markmann JF, Shaked A, Olthoff
KM. Intra-operative steroids are not required for liver transplant
immunosuppression. Amer J Transplantation 2002;2(3):198.
Debonera F, Que X, Aldeguer X,
Abt P, Gelman AE, Shaked A, Olthoff KM. Partial
liver grafts with prolonged cold preservation initiate blunted
regenerative responses. Amer J Transplantation 2002;2(3):1563.
Que X, Debonera F, Gelman AE,
Abt P, Shaked A, Olthoff KM. Intragraft IL-6
upregulation is criti-cal for graft survival after mouse liver
transplantation (mOLT). Amer J Transplanta 2002;2(3):453.
Abt P, Desai N, Crawford M, Markmann
J, Olthoff K, Shaked A. Liver transplantation
from non-heart beating donors: An increased incidence of biliary
complications. Amer J Transplantation 2002; 2(3):235.
Shetty K, Olthoff K, Read C,
Stewart C, Reddy R, Shaked A. Donor-evaluation
for living donor liver transplantation: Cost analysis of and
medical benefits. Hepatology 2002;36(4Pt2):197A.
Debonera F, Que X, Aldeguer X,
Abt P, Gelman AE, Shaked A, Olthoff KM. Partial
liver grafts with prolonged cold preservation initiate blunted
regenerative responses. Amer J Transplantation 2002;2(3):156.
Abt P, Desai N, Crawford M, Markmann
J, Olthoff K, Shaked A. Liver transplantation
from non-heart-beating donors: An increased incidence of biliary
complications. Amer J Transplantation 2002;2(3):235.
Que X, Debonera F, Gelman AE,
Abt P, Shaked A, Olthoff KM. Intragraft IL-6
upregulation is critical for graft survival after mouse liver
transplantation (mOLT). Amer J Transplantation 2002;2(3):453.
Shetty K, Olthoff K, Read C,
Stewart C, Reddy R, Shaked A. Donor evaluation
for living donor liver transplantation: Cost analysis and
medical benefits. Hepatology 2002;36(4 Pt2):197A.
Abt PL, Desai NJ, Crawford MD,
Forman L, Markmann JW, Olthoff KM, Markmann JF.
Survival following liver transplantation from non-heart-beating
donors. Hepatology 2002;36(4 Pt2):227A.
Shetty K, Brensinger CM, Timmins
K, Rattan S, Jayaraman V, Crawford M, Furth E, Krasinkas A,
Goldsmith J, Rosen M, Sun W, Reddy R, Shaked A,
Olthoff K. Liver transplantation for hepatocellular carcinoma:
Utility of selection criteria in predicting biological features
and outcome. Hepatology 2002;36(4 Pt2):389A.
Vesga L, Forman L, Shaked A.
The financial impact of liver transplantation. Am J Transplantation
2004;4:301.
Abt P, Rapaport-Kelz R, Frank
A, Campos L, Markmann J, Shaked A, Olthoff
K. Survival among pediatric liver transplant recipients: Impact
of segmental grafts. Am J Transplantation 2003;3(5) 306.
Blumberg EA, Shaked A,
Markmann J, Libetti G, Read C, Olthoff K. Outcomes of HIV
positive patients awaiting liver transplantation. Am J Transplantation
2003;3(5):433.
Olthoff KM, Timmins K, Shetty
K, Sun W, Furth EE, Soulen M, Shaked A. Outcomes
of pre-transplant local treatment for hepatocellular carcinoma
in the setting of cirrhosis. Am J Transplantation 2003;3(5):553.
Hasz R, Nathan H, Edwards J,
Abrams J, Mortiz M, Manzerbetia C, Reich D, Shaked
A, Olthoff K, Yang H. Successful kidney and liver
transplant outcomes from 150 non-heart beating donors (NHBD)
in a single OPO. Am J Transplantation 2003;3(5):557.
Abt P, Andrew G, Xin D, Wang
G, Xie J, Wells A, Olthoff K, Shaked A. Co-stimulatory
blockade does not affect in vivo memory cell function while
maintaining inhibition of alloimmune response. Am J Transplantation
2003;3(5):258.
Shetty , Sonnad S, Olthoff K,
Shaked A, Reddy R. Impact of the MELD score
on resource utilization following liver transplantation. Hepatology
2003;38(4):367A.
Shetty K, Olthoff K, Reddy R,
Shaked A. Cost comparison between cadaveric
and living donor liver transplantation. Hepatology 2003;38(4):652A.
Bloom R, Sayer G, Abt P, Shaked
A, Berns J, Reddy R. Outcome of hepatitis C virus
(HCV)-infected patients on the kidney transplant waiting list.
Am J Transplantation 2003;3:503.
Stewart C, Crawford M, Furth
O, Olthoff K, Shaked A. Does histology help
predict aggressive recurrent HCV after transplant. Am J Transplantation
2004;3:522.
Hasz R, Nathan H, Edwards J,
Abrams J, Moritz M, Manzerbetia C, Reich D, Shaked
A, Olthoff K, Yang H. Successful kidney and liver
transplant outcomes from 150 non-heart beating donors (NHBD)
in a single OPO. Am J Transplantation 2004;3:557.
Krasinskas AM, Minda J, Saul
SH, Shaked A, Furth EE. Redistribution of
thorotrast into a liver allograft several years following
transplantation: a case report. Mod Pathol 2004;17:117-120.
Gelman A, Abt, P, Xin D, Wang
G, Debonera F, Olthoff K, Wells A, Shaked A.
CTLA4Ig immunosuppression allows preservation of CD8+ T cell
memory response to tumor antigens; a potential advantage in
the transplant setting. Am J Transplantation 2004;4:191.
Shaked A, Tempie
E, Hulbert S, Everhart J, Merion R. Rejection is decreased
among adult recipients of living vs decreased donor liver
allografts. Am J Transplantation 2004;4:268.
Halpern S, Asch D, Stock P, Shaked
A, Blumberg E. Determinants of transplant surgeons'
willingness to provide organs for patients infected with the
hepatitis B, hepatitis C, and human immunodeficiency viruses.
Am J Transplantation 2004;4:425.
Stephenson G, Abt P, Frank A,
Kaminski M, Shaked A, Markmann J, Olthoff
K. Successful transplantation of livers from older cadaveric
donors. Am J Transplantation 2004;4:518.
Editorials,
Reviews, Chapters
Imagawa
DK, Strange SM, Shaked A, Seu P, Colonna
JO, Farmer D, McDiarmid SV, Morrissey MP, Busuttil RW. Liver
Transplantation at UCLA: Report of Clinical Activities. In:
Clinical Transplants; Terasaki PL, Ed. UCLA Tissue Typing
Laboratory, Los Angeles, 1991;13:127-134.
Shaked
A, Goldstein R: Liver transplantation for Budd-Chiari
syndrome. Transplantation of the Liver. Busuttil RW, Klintmalm
G, eds. W.B. Saunders Co., Philadelphia. 1996;15:138-144.
Shaked
A. Means of genetic modulation in liver transplantation.
Transplantation of the Liver. Busuttil RW, Klintmalm G, eds.
W. B. Saunders Co., Philadelphia. 1996;75:789-795.
Freund
H, Shaked A. Neutropenic enterocolitis. Letter
to the Editor, Dis. Colon & Rectum. 984; 27: 275.
Shaked
A, Calderon I, Durst A. Safety of surgical procedures
performed by residents. Letter to the Editor, Arch Surg. 1992;
127: 993.
Zamir,
GA, Olthoff KM, Nunes, FA, Shaked A et al.
Liver transplantation at the University of Pennsylvania and
The Children’s Hospital of Philadelphia. Clinical Transplants;
Cecka JM, Terasaki PL eds. UCLA Immunogenetics Center, Los
Angeles, 1999;20:223-229.
Zamir
G, Olthoff KM, Shaked A. Gene therapy and
graft modification. Curr Opin Organ Transpl 2001;6:343-347.
Barker
CF, Brayman KL, Markmann JF, Naji A, Olthoff KM, Shaked
A. Transplantation of Abdominal Organs. In: Beauchamp,
Evers, Matton, Eds. Sabiston Textbook of Surgery, 16th Edition,
Chapter 25: pp 429-470, 2001.
Rand
E, Olthoff KM. Pediatric Liver Transplantation. In: Lucey
M. Neuberger J, Shaked A, Eds. Liver Transplantation,
Chapter 10: pp 109-115, Landes Bioscience, 2002.
Rand
E, Olthoff KM. Pediatric Liver Transplantation. In: Lucey
M. Neuberger J, Shaked A, Eds. Liver Transplantation,
Chapter 10: pp 109-115, Landes Bioscience, 2002.
Olthoff
KM, Abt, PL, Shaked A. Liver Transplantation.
In: Reddy KR, Long WB, Eds. Requisites in Gastroenterology,
Volume 3: Hepatobiliary Tract and Pancreas, Chapter 12: pp
243-255, Mosby, 2004.
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