Schnitzer
JJ, Hedrick HL, Pacheco BA, Losty PD, Ryan
DP, Doody DP, Donahoe PK. Prenatal glucocorticoid therapy
reverses pulmonary immaturity in congenital diaphragmatic
hernia in fetal sheep. Annals of Surgery 224(4):430-439, Oct.
1996.
Schnitzer JJ, Thompson
JE, Hedrick HL, Kaban JM, Wilson JM. High
frequency intratracheal pulmonary ventilation: improved gas
exchange at lower airway pressures. Journal of Pediatric Surgery
32(2):203-206, Feb. 1997.
Hedrick HL,
Kaban JM, Pacheco BA, Losty PD, Doody DP, Ryan DP, Manganaro
TF, Donahoe PK, Schnitzer JJ. Prenatal glucocorticoids improve
pulmonary morphometrics in fetal sheep with congenital diaphragmatic
hernia. Journal of Pediatric Surgery 32(2):217-222, Feb. 1997.
Schnitzer JJ, Thompson
JE, Hedrick HL. A new ventilator improves
CO2 removal in newborn lambs with congenital diaphragmatic
hernia. Critical Care Medicine 27(1):109-112, Jan. 1999.
Nance ML, Adamson WT, Hedrick
HL. Appendicitis in the young child: A continuing
diagnostic challenge. Pediatric Emergency Care 16(3):160-162,
June 2000.
McElhinney DB, Hedrick
HL, Bush DM, Pereira GR, Stafford PW, Gaynor JW,
Spray TL, Wernovsky G. Necrotizing enterocolitis in neonates
with congenital heart disease: Risk factors and outcomes.
Pediatrics 106(5):1080-1087, Nov. 2000.
Hedrick HL,
Nelson RM. Handling ethical conflicts in the clinical setting.
Seminars in Pediatric Surgery 10(4):192-197, Nov. 2001.
Crombleholme TM, Coleman
B, Hedrick H, Liechty K, Howell L, Flake
AW, Johnson M, Adzick NS. Cystic adenomatoid malformation
volume ratio predicts outcome in prenatally diagnosed cystic
adenomatoid malformation of the lung. Journal of Pediatric
Surgery 37(3):331-338, Mar. 2002.
Davey MG, Hedrick
HL, Mendoza JM, Kanai M, Adzick NS, Flake AW. Pulmonary
epithelial liquid absorption, expressed in relation to alveolar
surface area, is reduced in fetal lambs following in utero
tracheal occlusion. Pediatric Pulmonology 34(4):278-286, Oct.
2002.
Davey MG, Hedrick
HL, Bouchard S, Mendoza JM, Schwarz U, Adzick NS,
Flake AW. Temporary tracheal occlusion in fetal sheep with
lung hypoplasia does not improve postnatal lung function.
Journal of Applied Physiology 94(3):1054-62, Mar. 2003.
Davey MG, Hedrick
HL, Bouchard S, Adzick NS, Flake AW, Doolin EJ. Computer-assisted
stereology: Point fraction of lung parenchyma and alveolar
surface density in fetal and newborn sheep. Scanning 25(1):37-44,
Jan./Feb. 2003.
Keswani SG, Johnson MP,
Adzick NS, Hori S, Howell LJ, Wilson RD, Hedrick H,
Flake AW, Crombleholme TM. In utero limb salvage: Fetoscopic
release of amniotic bands for threatened limb amputation.
Journal of Pediatric Surgery 38(6):848-851, June 2003.
Lim FY, Crombleholme TM,
Hedrick HL, Flake AW, Johnson MP, Howell
LJ, Adzick NS. Congenital high airway obstruction syndrome:
Natural history and management. Journal of Pediatric Surgery
38(6):940-945, June 2003.
Hedrick HL.
Ex utero intrapartum therapy. Seminars in Pediatric Surgery
12(3):190-195, Aug. 2003.
Johnson MP, Sutton LN,
Rintoul N, Crombleholme TM, Flake AW, Howell LJ, Hedrick
HL, Wilson RD, Adzick NS. Fetal myelomeningocele
repair: Short-term clinical outcomes. American Journal of
Obstetrics & Gynecology 189(2):482-487, Aug. 2003.
Wilson RD, Johnson MP,
Crombleholme TM, Flake AW, Hedrick HL, King
M, Howell LJ, Adzick NS. Chorioamniotic membrane separation
following open fetal surgery: Pregnancy outcome. Fetal Diagnosis
& Therapy 18(5):314-320, Sept./Oct. 2003.
Hedrick HL,
Crombleholme TM, Flake AW, Nance ML, von Allmen D, Howell
LJ, Johnson MP, Wilson RD, Adzick NS. Right congenital diaphragmatic
hernia: Prenatal assessment and outcome. Journal of Pediatric
Surgery 39(3):319-323, Mar. 2004.
Hedrick HL,
Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD,
Adzick NS. Sacrococcygeal teratoma: Prenatal assessment, fetal
intervention, and outcome. Journal of Pediatric Surgery 39(3):430-438,
Mar. 2004.
Wilson RD, Baxter JK, Johnson
MP, King M, Kasperski S, Crombleholme TM, Flake AW, Hedrick
HL, Howell LJ, Adzick NS. Thoracoamniotic shunts:
Fetal treatment of pleural effusions and congenital cystic
adenomatoid malformations. Fetal Diagnosis & Therapy 19(5):413-420,
Sept./Oct. 2004.
Wilson RD, Johnson MP, Flake
AW, Crombleholme TM, Hedrick HL, Wilson J,
Adzick NS. Reproductive outcomes after pregnancy complicated
by maternal-fetal surgery. American Journal of Obstetrics
& Gynecology 191(4):1430-1436, Oct. 2004.
Danzer E, Johnson MP, Wilson
RD, Flake AW, Hedrick HL, Sutton LN, Adzick
NS. Fetal head biometry following in-utero repair of myelomeningocele.
Ultrasound in Obstetrics & Gynecology 24(6):606-611, Nov.
2004.
Keswani SG, Crombleholme TM,
Pawel BR, Johnson MP, Flake AW, Hedrick HL,
Howell LJ, Wilson RD, Davis GH, Adzick NS. Prenatal diagnosis
and management of mainstem bronchial atresia. Fetal Diagnosis
& Therapy 20(1):74-78, Jan./Feb. 2005.
Davey MG, Biard JM, Robinson
L, Tsai J, Schwarz U, Danzer E, Adzick NS, Flake AW, Hedrick
HL. Surfactant protein expression is increased in
the ipsilateral but not contralateral lungs of fetal sheep
with left-sided diaphragmatic hernia. Pediatric Pulmonology
39(4):359-367, Apr. 2005.
Hedrick HL,
Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD,
Adzick NS. The ex utero intrapartum therapy procedure for
high-risk fetal lung lesions. Journal of Pediatric Surgery
40(6):1038-1044, June 2005.
Keswani SG, Crombleholme TM,
Tychik J, Tian Z, Mackenzie TC, Johnson MP, Wilson RD, Flake
AW, Hedrick HL, Howell LJ, Adzick NS. Impact
of continuous intraoperative monitoring on outcomes in open
fetal surgery. Fetal Diagnosis & Therapy 20(4):316-320,
July/Aug. 2005.
DeMatos V, Russo P, Hedrick
H, Piccoli D, Mamula P. A 2 year old girl with persistent
ascites. Medscape case report, Aug. 2005.
Jackson MB, Guttenberg M, Hedrick
H, Moshang T. Multiple endocrine neoplasia type 2A
in a kindred with C634Y mutation. Pediatrics 116(3):e468-71,
Sept. 2005.
Biard JM, Johnson MP, Carr MC,
Wilson RD, Hedrick HL, Pavlock C, Adzick
NS. Long-term outcomes in children treated by prenatal vesicoamniotic
shunting for lower urinary tract obstruction. Obstetrics &
Gynecology 106(3):503-508, Sept. 2005.
Liechty KW, Hedrick HL,
Hubbard AM, Johnson MP, Wilson RD, Ruchelli ED, Howell LJ,
Crombleholme TM, Flake AW, Adzick NS. Severe pulmonary hypoplasia
associated with giant cervical teratomas. Journal of Pediatric
Surgery 41(1):230-233, Jan. 2006.
Danzer E, Robinson LE, Davey
MG, Schwarz U, Volpe MA, Adzick NS, Flake AW, Hedrick
HL. Tracheal occlusion in fetal rats alters expression
of mesenchymal nuclear transcription factors without affecting
surfactant protein expression. Journal of Pediatric Surgery
2006 (in press).
Danzer E, Hubbard AM, Hedrick
HL, Johnson MP, Wilson RD, Howell LJ, Flake AW, Adzick
NS. Diagnosis and characterization of fetal sacrococcygeal
teratoma with prenatal MR imaging. American Journal of Roentgenology
2006 (in press).
Reviews in
Peer Reviewed Research Publications
MacKenzie TC, Crombleholme TM, Johnson MP, Schnaufer L, Flake
AW, Hedrick HL, Howell LN, Adzick NS. The
natural history of prenatally diagnosed conjoined twins. [Review]
Journal of Pediatric Surgery 37(3):303-309, Mar. 2002.
Hedrick HL,
Flake AW, Crombleholme TM, Howell LJ, Johnson MP, Wilson RD,
Adzick NS. History of fetal diagnosis and therapy: Children's
Hospital of Philadelphia experience. [Review] Fetal Diagnosis
& Therapy 18(2):65-82, Mar./Apr. 2003.
Biard JM, Wilson RD, Johnson
MP, Hedrick HL, Schwarz U, Flake AW, Crombleholme
TM, Adzick NS. Prenatally diagnosed giant omphaloceles: Short-
and long-term outcomes. [Review] Prenatal Diagnosis 24(6):434-439,
June 2004.
Rychik J, Tian Z, Cohen MS, Ewing
SG, Cohen D, Howell LJ, Wilson RD, Johnson MP, Hedrick
HL, Flake AW, Crombleholme TM, Adzick NS. Acute cardiovascular
effects of fetal surgery in the human. [Review] Circulation
110(12):1549-1556, Sept. 21, 2004.
Research
Publications, Non-Peer-Reviewed
Hedrick HL, Pacheco BA, Losty PD, Donahoe
PK, Schnitzer JJ. Dexamethasone increases expression of surfactant
associated protein mRNA in rats with nitrofen-induced congential
diaphragmatic hernia. Surgical Forum 66:654-657, 1995.
Hedrick
HL, Kaufman OE, Teixeira JM, Donahoe PK, Schnitzer
JJ. Analysis of gene expression in scarless fetal vs. postnatal
skin. Surgical Forum 67:670-673, 1996.
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