Hwang HC, Smythe WR, Elshami AA, Kucharczuk JC, Amin KM, Williams JL, Litzky LA, Kaiser LR, Albelda SM: Gene therapy using adenovirus carrying the herpes simplex-thy-midine kinase gene to treat in vivo models of human malignant mesothelioma and lung cancer. American Journal of Respiratory Cell & Molecular Biology, 13(1):7-16, July 1995.

Kucharczuk JC, Elshami AA, Zhang HB, Smythe WR, Hwang HC, Tomlinson JS, Amin KM, Litzky LA, Albelda SM, Kaiser LR: Plerual-based mesothelioma in immune competent rats: A model to adenoviral gene transfer. Annals of Thoracic Surgery, 60(3):593-598, Sept. 1995.

Elshami A, Kucharczuk JC, Sterman DH, Smythe WR, Hwang HC, Amin KM, Litzky LA, Albelda SM, Kaiser LR. The role of immune suppression in the efficacy of cancer gene therapy using adenovirus transfer of the Herpes Simplex-thymidine kinase gene. Annals of Surgery, 222(3):298-310, Sept. 1995.

Elshami AA, Kucharczuk JC, Zhang HB, Smythe WR, Litzky LA, Hwang HC, Kaiser LR, Albelda SM: Treatment of pleural mesothelioma in an immunocompetent rat model utilizing adenoviral transfer of the HSV-thymidine kinase gene. Human Gene Therapy, 7(2):141-148, Jan. 20, 1996.

Elshami AA, Saavedra A, Zhang HB, Kucharczuk JC, Spray D, Fishman GI, Kaiser LR, Albelda SM: Gap junctions play a role in the “bystander effect” of the herpes simplex virus thymidine kinase/ganciclovir system in vitro. Gene Therapy, 3(1):85-92, Jan. 1996.

Randazzo BT, Kucharczuk JC, Litzky LA, Brown MS, Kaiser LR, Fraser NW, Albelda SM: Herpes simplex 1716--- an ICP 34.5 mutant--- is severely replication restricted in human skin xenografts in vivo. Virology, 223(2):392-395, Sept. 15, 1996.

Kucharczuk JC, Raper S, Elshami AA, Smythe WR, Litzky LA, Kaiser LR, Albelda SM: Safety of intrapleurally administered recombinant adenovirus carrying herpes simplex thymidine kinase DNA followed by ganciclovir therapy in nonhuman primates. Human Gene Therapy, 7(18):2225-2233, Dec. 1, 1996.

Kucharczuk JC, Randazzo BT, Elshami AA, Sterman DH, Rizk NP, Amin KM, Molnar-Kimber KL, Brown MS, Litzky LA, Fraser NW, Albelda SM, Kaiser LR: Use of a “replication-restricted” herpes virus to treat experimental human malignant mesothelioma. Cancer Research, 57(3):466-471, Feb. 1, 1997.

Kucharczuk JC, Cohen ML, Rhodes LA, Karl TR, Spray TL, Gaynor JW: Epicardial atrial pacemaker lead placement following multiple cardiac operations. Accepted for Publication, Annals of Thoracic Surgery, 71:2057-2058, June 2001.

Deeb ME, Brinster CJ, Kucharczuk JC, Shrager JB, Kaiser LR. Expanded indications for transcervical thymectomy in the management of anterior mediastinal masses. Annals of Thoracic Surgery, 72:208-211, July 2001.

Marshall MB, Deeb ME, Bleier JL, Kucharczuk JC, Friedberg JS, Kaiser LR, Shrager JB. Suction vs. water seal after pulmonary resection: A randomized prospective study. Chest, 121(3): 831-835, March 2002.

Singhal S, Weiwrodt R, Malden, L, Matzie K, Friedberg J, Amin KM, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM. Gene expression mapping of malign-nant mesothelioma. Clinical Cancer Research, 9(8):3080-3097, Aug. 1, 2003.

Singhal S, Amin KM, Kruklitis R, Marshall MB, Kucharczuk JC, DeLong P, Litzky LA, Kaiser LR, Albelda SM. Differentially expressed apoptotic genes in early stage lung adenocarcinoma predicted by expression profiling. Cancer Biology & Therapy, 2(5):566-571, Sept./Oct. 2003.

Kucharczuk JC, Kaiser LR, Marshall MB. Weerda Diverticuloscope: Novel technique for removal of esophageal foreign body. Annals of Thoracic Surgery, 76(4):1276-1278, Oct. 2003.

Paulson EC, Singhal S, Kucharczuk JC, Sterman DH, Kaiser LR, Marshall MB. Bronchial sleeve resection for posttransplant stricture. Annals of Thoracic Surgery, 76(6):2075-2076, Dec. 2003.

Brinster CJ, Singhal S, Lawrence L, Marshall MB, Kaiser LR, Kucharczuk JC. Evolving options in the management of esophageal perforation. Annals of Thoracic Surgery, 77(4):1475-1483, Apr. 2004.

Marshall, MB, Kaiser LR, Kucharczuk JC. Simple technique for maximal thoracic muscle harvest. Annals of Thoracic Surgery 77(4):1465-1466, Apr. 2004.

Ahmed Z, Marshall MB, Kucharczuk JC, Kaiser LR, Shrager JB. Lung cancer in trans-plant recipients: A single institution experience. Archives of Surgery 139(8):902-906, Aug. 2004.

Marshall MB, Ahmed Z, Kucharczuk JC, Kaiser LR, Shrager JB. Catamenial pneumo-thorax: optimal hormonal and surgical management. European Journal of Cardio-Thoracic Surgery 27(4):662-666, Apr. 2005.

Lee L, Nance M, Kaiser LR, Kucharczuk JC. Familial massive leiomyoma with esophageal leiomyomatosis: An unusual presentation in a father and his two daughters. Journal of Pediatric Surgery 40(5):e29-32, May 2005.

Kucharczuk JC, Kaiser LR. Radical lobectomy, esophagectomy, and mediastinal dissections for intrathoracic malignancy. Surgical Oncology Clinics of North America 14(3):499-509, vi, July 2005.

O'Brien PK, Kucharczuk JC, Marshall MB, Friedberg JS, Chen Z, Kaiser LR, Shrager JB. Comparative study of subxiphoid versus video-thoracoscopic pericardial "window". Annals of Thoracic Surgery 80(6):2013-2019, Dec. 2005.

Marshall MB, Kucharczuk JC, Shrager JB, Kaiser LR. Anterior surgical approaches to the thoracic outlet. Journal of Thoracic & Cardiovascular Surgery. 131(6):1255-60, Jun 2006.

Levine S, Nguyen T, Friscia M, Zhu J, Szeto W, Kucharczuk JC, Tikunov B, Rubinstein N, Kaiser LR, Shrager JB. Parasternal Intercostal muscle remodeling in severe chronic obstructive pulmonary disease. Journal of Applied Physiology 101:1297-1302, 2006. [Epub ahead of print, June 22, 2006]

Kreider ME, Hansen-Flaschen J, Ahmand N, Rossman MD, Kaiser LR, Kucharczuk JC, Shrager JB. Complications of video-assisted thoracoscopic lung biopsy in patients with interstitial lung disease. Annals of Thoracic Surgery 83(3):1140-1144, Mar. 2007.

Willmont AS, Levine MS, Rubesin SE, Kucharczuk JC, Laufer I. Intraluminal migration of surgical drains after transhiatal esophagogastrectomy: Radiographic findings and clinical relevance. American Journal of Roentgenology 189(4):780-785, Oct. 2007.

Vachani Anil; Nebozhyn Michael; Singhal Sunil; Alila Linda; Wakeam Elliot; Muschel Ruth; Powell Charles A; Gaffney Patrick; Singh Bhuvanesh; Brose Marcia S; Litzky Leslie A; Kucharczuk John; Kaiser Larry R; Marron J Stephen; Showe Michael K; Albelda Steven M; Showe Louise C. A 10-gene classifier for distinguishing head and neck squamous cell carcinoma and lung squamous cell carcinoma. Clinical cancer research 13(10):2905-15, May 2007.

Ra J, Paulson EC, Kucharczuk J, Armstrong K, Wirtalla C, Rapaport-Kelz R, Kaiser LR, Spitz FR. Postoperative mortality after esophagectomy for cancer: development of a preoperative risk prediction model. Annals of Surgical Oncology 15(6):1577-1584, June 2008.

Wright C, Kucharczuk J, O’Brien S, Grab J, Allen M, Society of Thoracic Surgeons General Thoracic Surgery Database. Predictors of major morbidity and mortality after esophgectomoy for esophageal cancer: a Society of Thoracic Surgeons General Thoracic Surgery Database risk adjustment model. Journal of Thoracic Cardiovascular Surgery. 137(3):587-95; discussion 596, March 2009.

Kucharczuk J. Invited Commentary. Hybrid Techniques for the management of acute esophageal perforations. Ann Thorac Surg 88(1): 199, 2009.

Reviews in Peer-Reviewed Research Publications
Lee LS, Singhal S, Brinster CJ, Marshall B, Kochman ML, Kaiser LR, Kucharczuk JC. Current management of esophageal leiomyoma. [Review] Journal of the American College of Surgeons, 198(1):136-146, Jan. 2004.

Kucharczuk JC. Radiofrequency ablation: Emerging therapy for the small pulmonary nodule? [Review] Seminars in Thoracic & Cardiovascular Surgery 17(2):134-137, 2005.

Abstracts
Singhal S, Lee L, Brinster C, Friedberg J, Amin KA, Kucharczuk JC, Johnson SW, Sterman D, Kaiser LR, Albelda SM. “Genomic Profiling to Explain Positive PET-18FDG Imaging in Patients with Malignant Pleural Mesothelioma.” American Association of Surgery. 36th Annual Meeting. Novermber 7, 2002.

Singhal S, Weiwrodt R, Malden, L, Matzie K, Friedberg J, Amin KM, Kucharczuk JC, Litzky LA, Johnson SW, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” American College of Surgeons.88th Annual Meeting. San Francisco, California. October 9, 2002.

Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” University of Pennsylvania 8th Annual Respiration Research Retreat. Germantown, PA. June 21, 2002.

Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” University of Pennsylvania Department of Medicine Research Retreat. Philadelphia, PA. May 15, 2002.

Singhal S, Weiwrodt R, Matzie K, Friedberg J, Kucharczuk J, Kaiser LR, Albelda SM. “Gene Expression Mapping to Diagnose Malignant Mesothelioma.” The Eunice and Irving Annual Scientific Symposium: Advances in Cancer Research. Philadelphia, PA. March 26, 2002.

Kucharczuk JC, Marshall MB, Singhal S, Shrager JB, Kaiser LK. Needlescopic Sympathectomy for Palmar Hyperhidrosis. The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting. Miami FL, October 16-20, 2002.

Kruklitis R, Singhal S, Greenberg J, Marshall MB, Shrager JB, Sterman DH, Kaiser LR, Kucharczuk JC. Endobronchial Surgery for Removal of Endobronchial Hamartomas. The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting. Miami FL, October 16-20, 2002.

Marshall MB, Kucharczuk JC, Shrager JB, Kaiser LR. Anterior Transcervical Thoracic Approach for NSCLC: Lessons Learned. The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting. Miami FL, October 16-20, 2002.

Singhal S, Kucharczuk JC, Marshall MB, Kruklitis RJ, Friscia M, Shrager JB, Albleda SM, Kaiser LR. Transcriptional Profiling of Malignant Mesothelioma Using cDNA Microarrays. The Pennsylvania Association for Thoracic Surgery 40th Annual Meeting. Miami FL, October 16-20, 2002.

Singhal S, Kucharczuk JC, Marshall MB, Albelda SM, Kaiser LR. Transcript profiling of patients with N0 lung adenocarcinomas to predict survival. 83rd Annual Meeting of the American Association for Thoracic Surgery, Boston, MA, May 4-7, 2003.

Singhal S, Kruklitis, RJ, Marshall MB, Kucharczuk JC, Albelda SM, Kaiser LR. Viral gene transfer of IL-12 prolongs survival and prevents recurrence in early and advanced non-small cell lung cancer. Surgical Forum of the American College of Surgeons, 2003.

Ahmed Z, Marshall MB, Kucharczuk JC, Kaiser LR, Shrager JB. Bronchogenic Carci-noma in immunosupressed transplant recipients. Presented at the Surgical Forum of the American College of Surgeons, 2003.

Kreider ME, Ahmad NN, Hansen-Flaschen JC, Kaiser LR, Brinster C, Kucharczuk JC, Shrager JB. Complications of thoracoscopic lung biopsy in patients with interstitial lung disease. Presented at the American College of Chest Physicians Meeting, Montreal, CA Nov. 2005.

Shrager JB, Nathan DP, Spence AM, Kurichi JE, Kucharczuk JC, Kaiser LR. Compara-tive study of anterior and posterior approaches to pancoast tumors at a single institution. Presented at the American Association for Thoracic Surgery, Philadelphia, PA, May 2006.

Kucharczuk JC, Shrager JB, Kaiser LR, Cooper JD. Transcervical Thymectomy for Non Thymomatous Myasthenia Gravis. Society of Thoracic Surgery. January 2007, San Diego CA.

Kucharczuk JC, Cooper JD. Tracheal resection for subglotic stenosis. Presented at the General Thoracic Surgical Club 25th Annual Meeting, Captiva Island, FL, Feb 15, 2007.

Cornelius, K, Abbott, P, Moore B, Murphy J, Kucharczuk JC. Lobectomy for lung cancer in the octogenarian; is age a risk factor? A single institutional general thoracic database review. Presented at the Society of Thoracic Surgeons Advances in Quality and Outcomes Meeting, Minneapolis, MN, Nov. 1-3, 2007.

Kucharczuk JC, Shrager JB, Kaiser LR, Cooper JD. Tracheal Resection with Primary Reconstruction for subglottic stricture following tracheostomy. Presented at the 44th Annual Society of Thoracic Surgeons Meeting, Fort Lauderdale, FL, Jan. 29, 2007.

Paulson EC, Ra J, Wirtalla C, Rohrbach J, Kelz R, Cooper J, Rosato E, Gorman J, Kaiser L, Kucharczuk JC, Spitz F. Predictors of postoperative course following esophagectomy at a high volume institution. Presented at the Academic Surgical Congress, Huntington Beach, CA, Feb. 15, 2008.

Wright CD, Allen MS, Grab JD, Kucharczuk JC: Predictors of Major Morbidity and Mortality after Esophagectomy for Esophageal Cancer: An STS General Thoracic Surgery Database Risk Adjustment Model. : Plenary Session, American Association for Thoracic Surgery 88th Annual Meeting, San Diego, CA. May 12, 2008.

Kucharczuk JC, SU S, Cooper JD. Resection of Giant Right Epiphrenic Diverticulum and Hiatal Repair via a Belsey Wrap. 22nd Annual Meeting of The General Thoracic Surgical Club. St. Petersburg Florida. March 13, 2009.

Sanchez PG, Kucharczuk JC, Su S, Kaiser LR, Cooper JD. NETT Redux (Accentuating the Positive). Simultaneous Scientific Session. American Association for Thoracic Surgery 89 th Annual Meeting, Boston Mass, May 11, 2009.

Itkin M, Kucharczuk JC, Trerotola S, Kwak A, Cope C, Kaiser LR. Non Operative Thoracic Duct Embolization for traumatic Chylothorax: Experience in 103 patients. Accepted for Presentation: Plenary Session, American Association for Thoracic Surgery 89 th Annual Meeting, Boston Mass, May 12, 2009.

A. Berman, S. Singhal, S. Su, Kucharczuk JC, J. Cooper, J. Shrager, L. Kaiser, J. Friedberg, J. Faerber, T. Evans, J. Stevenson, C.J. Langer, J. Metz, E. Glatstein, S.M. Hahn, R. Rengan: Adjuvant Radiotherapy for Completely Resected Stage II Thymoma. International Association for the study of Lung Cancer. 13th World Conference on Lung Cancer. San Francisco CA, July 31, 2009.

A. Trister, C. Gillespie, A. Haas, D. Sterman, Kucharczuk JC, J. Cooper, J. Friedberg, J. Wobb, T. Lucas, D. Pryma, C. Divgi, L. Lin, R. Rengan : Prognostic Value of Primary Tumor FDG Uptake for Occult Mediastinal Lymph Node Involvement in N2 Node Negative Non Small Cell Lung Cancer as Staged by Positron Emission Tomography. International Association for the study of Lung Cancer. 13th World Conference on Lung Cancer. San Francisco CA, July 31, 2009.

R. Rengan, R. Mick, L. Lin, A. Maity, A. Gupta, T. Evans, J. Stevenson, C.J. Langer MD, Kucharczuk JC, J. Friedberg, S. Prendergast, J. Driesbaugh, and S.M. Hahn: Early Results of a Phase I Trial of the HIV Protease Inhibitor Nelfinavir with Concurrent Chemoradiotherapy (CT-RT) for Stage IIIA/IIIB NSCLC. International Association for the study of Lung Cancer. 13th World Conference on Lung Cancer. San Francisco CA, July 31, 2009.

Weiss J, Evans T, Eaby B, Stevenson J, Kucharczuk J, CooperJ , Kaiser L, Shrager J, Rengan R, Langer C. Adjuvant Cisplatin and Docetaxel (CDDP-Doc) for Non small cell Lung Cancer (NSCLC): the Hospital of the University of Pennsylvania (HUP) Experience. 13th World Conference on Lung Cancer. San Francisco CA, July 31, 2009.

Editorials, Chapters & Participation in Committee Reports
Buzby GP, Kucharczuk JC. Changes in immunologic function. Chap. 23 in Nutrition and Metabolism in the Surgical Patient, Second Edition. Fischer JE (ed). Boston: Little, Brown & Co., 1995, 623-635.

Kucharczuk JC, Kaiser LR. Invited Review: Literature review in video-assisted thoracic surgery. Contemporary Surgery, Nov. 2002.

Kucharczuk JC. Cancer of the lung from molecular biology to treatment guidelines (Weitberg AB, editor). Human Pathology, 33(4):451, Apr. 2002.

Kucharczuk JC. Invited book review: Thoracic surgical oncology: Exposures & tech-niques (Nesbit JG & Wind GG, eds). Annals of Thoracic Surgery 77(1):167, Jan. 2004.

Kucharczuk JC, Kaiser LR. Radical lobectomy, esophagectomy and mediastinal dissections for intra thoracic malignancy. Surgical Clinics of North America: The Evolutions of Radical Cancer Surgery in Oncology. 14(3):499-509, July 2005.

Kucharczuk JC, Shrager JB. Anterior mediastinal masses. In Sabiston & Spencer: Surgery of the Chest, Seventh Edition. Sellke F, Swanson S, del Nido P (eds.). New York: Elsevier, 2005, 667-680.

Kucharczuk JC. Surgical approaches to esophageal neoplasms. Chap. 2 in The Clinician's Guide to Gastrointestinal Oncology. Kochman M (ed.). Thorofare, NJ: SLACK Incorporated Professional Book Division, 2005, 11-22.

Kucharczuk JC, Kaiser LR. Esophageal tumors and injury. Greenfield’s Surgery: Scientific Principles & Practice, 4th Edition. Greenfield, LJ (ed). Philadelphia: Lippincott Williams & Wilkins, 2006, 691-708.

Kucharczuk JC, Kaiser LR. Bronchoscopy. Chap. 7 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds). London: Oxford University Press, 2006, 63-72.

Kucharczuk JC. The pericardium. Chap. 29 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds). London: Oxford University Press, 2006, 307-314.

Kucharczuk JC, Kaiser LR. Extrapleural pneumonectomy. Chap. 30 in Operative Thoracic Surgery. Jamieson GJ, Kaiser LR (eds). London: Oxford University Press, 2006, 315-324.

Kucharczuk JC. Chest wall resection. Mastery of Cardiothoracic Surgery, 2nd Edition. Kaiser LR, Kron IL, Spray TL (eds.). Philadelphia: Lippincott Williams & Wilkins, 2007, 222-227.

Kucharczuk JC, Kaiser LR. Surgical techniques: Surgery of pectus deformities. Chap. 108 in Pearson’s Thoracic Surgery 3rd Edition. Philadelphia: Churchill Livingstone, 2007, 1329-1339.

Kucharczuk JC, Cooper JD. Transcervical thymectomy for non thymomatous myasthenia gravis. Chap. 141 In Pearson’s Thoracic Surgery 3rd Edition. Philadelphia: Churchill Livingstone, 2007, 1715-1719.

Kucharczuk, JC. ACP XXI: Disorders of the mediastinum and hila. American College of Physicians Medicine. WebMD Inc, 2008.

Kucharczuk JC. Diagnostic Procedures in Thoracic Surgery. Sugical Pitfalls. Elsevier, November 2008

Rascoe P, Kucharczuk JC, Cooper JD. Surgery of the Mediastinum Historical Notes. Thoracic Surgical Clinics. Volume 19 (1), February 2009.

Kucharczuk JC, Cooper JD. Surgical technique: Transcervical thymectomy. Chapt. 134 in Adult Chest Surgery. New York: McGraw Hill, 2009, 1115-1120.

Rascoe P, Kucharczuk JC, Kaiser LR. Esophageal tumors and injury. Greenfield’s Surgery: Scientific Priciples and Practice. 5th Edition. Greenfield, LJ (ed). 2009.

Chung H, Kucharczuk JC, Shrager JB. Anterior mediastinal masses. Sabiston & Spencer: Surgery of the Chest, 8th t Edition. New York: Elsevier, 2009 , (in press).

Rascoe P, Kucharczuk JC, Kaiser LR. Esophageal Cancer in the Elderly Patient. Principles and Practice of Geriatric Surgery, Second Edition, edited by Drs. Rosenthal, Katlic and Zenilman. 2009, (in press).

Alternative Media
Kucharczuk JC. Review, Pier on line Project, American College of Physicians-American Society of Internal Medicine, Pneumothorax Module 2002.

Kucharczuk JC. TissueLink resection of metastatic renal cell to the lung with en-bloc chest wall resection. (multimedia presentation) WWW.Tissuelink.com.

Kucharczuk JC. Surgical management of lung abscess. Thoracic Surgery Directors Online Requisite Curriculum Publication http://www.tsda.org/curriculum/entry.htm, July 2003.

Kucharczuk JC. Congenital lung abnormalities module: Pulmonary sequestration. Multimedia Presentation. Thoracic Surgery Directors Requisite Online Curriculum Publication. http://www.tsda.org/curriculum/entry.htm, July 2003.

Kucharczuk JC, Kaiser LR. Resection of symptomatic, complex aspergilloma.
Available at: http://www.ctsnet.org/doc/8793. Posted Feb. 9, 2004.

Kucharczuk JC. 2: Chest Wall Mass, 4: Thorax. ACS Surgery Online. Souba WW, Fink MP, Jurkovich, GJ et al, Eds. WebMD Inc., New York 2005 http://www.acssurgery/ Oct. 2005.

Kucharczuk JC. American College of Surgeon’s Weekly Curriculum: Apr. 5, 2006 -- Chest Wall Mass, http://www.acssurgery.com/acsw, The ACS Surgery Weekly Curriculum, 111 Eighth Avenue, Suite 700, New York, NY 10011, Posted Apr. 5, 2006.

Patents
Kucharczuk JC. Application No.09/117,218 USPTO: Treatment of Non-Neuronal Cancer Using HSV Mutant (Application under review).