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Najjia N. Mahmoud, M.D.
Colon and Rectal Surgery
 

Research Publications, peer reviewed
Paulson JR, Mesner PW, Delrow JJ, Mahmoud NN, Ciesielski WI. Rapid Analysis of Mitotic Histone H1 Phosphorylation By Cationic Disc Electrophoresis at Neutral pH in Minigels. Analytical Biochemistry 203(2):124-137, June 1992.

Bertagnolli MM, Mahmoud NN, Daly JN. Surgical Aspects of Colorectal Cancer. Hematology-Oncology Clinics of North America 11(4):655-677, Aug. 1997.

Mahmoud NN, Boolbol SK, Bilinski RT, Martucci C, Chadburn A, Bertagnolli MM. The APC Gene Mutation Creates a Dominant Negative Effect on Intestinal Cell Migration. Cancer Research 57(22):5045-5050, Nov. 15, 1997.

Mahmoud NN, Boolbol SK, Dannenberg AJ, Mestre JR, Bilinski RT, Martucci C, Newmark HL, Chadburn A, Bertagnolli MM. The Sulfide Metabolite of Sulindac Prevents Tumors and Restores Enterocyte Apoptosis in a Murine Model of Familial Adenomatous Polyposis. Carcinogenesis 19(1):87-91, Jan. 1998.

Mahmoud NN, Dannenberg AJ, Mestre J, Bilinski RT, Martucci C, Newmark H, Bertagnolli MM. Aspirin Prevents Tumors in a Murine Model of Familial Adenomatous Polyposis. Surgery, 124(2):225-231, Aug. 1998.

Mahmoud NN, Bilinski RT, Churchill MR, Edelmann W, Kucherlapati R, Bertagnolli MM. Genotype-Phenotype Correlation in Murine Apc Mutation: Differences in Enterocyte Migration and Response to Sulindac. Cancer Research 59(2):353-359, Jan. 15, 1999.

Mahmoud NN, Mack CA, DeCosse JJ, Michaeli J, Bertagnolli MM. Debulking of a Gastrointestinal Hemangioma Alleviates Coagulopathy Associated with Kasabach-Merritt Syndrome. Surgery 125(2):236-238, Feb. 1999.

Mahmoud NN, Bilinski RT, Mestre J, Martucci C, Bertagnolli MM. Administration of an Unconjugated Bile Acid Increases Duodenal Tumors in a Murine Model of Familial Adenomatous Polyposis. Carcinogenesis 20(2):101-105, Feb. 1999.

Mahmoud NN, Carothers AM, Grunberger D, Bilinski RT, Churchill MR, Martucci C, Newmark HL, Bertagnolli MM. Phenolic Antioxidants Decrease Intestinal Tumors in an Animal Model of Familial Adenomatous Polyposis. Carcinogenesis 21(5):921-927, May 2000.

Weyant MJ, Carothers AM, Mahmoud NN, Bradlow HL, Remotti H, Bilinski RT, Bertagnolli MM. Reciprocal Expression of ERalpha and ERbeta is Associated with Estrogen-Mediated Modulation of Intestinal Tumorigenesis. Cancer Research 61(6):2547-2551, Mar. 15, 2001.

Stein D, Mahmoud NN, Rose D, Anne P, Goldstein S, Isenberg G, Mitchell E, Fry RD. A Longer Time Interval between Completion of Neoadjuvant Chemoradiation and Surgical Resection does not Improve Downstaging of Rectal Carcinoma. Diseases of the Colon and Rectum, Vol. 46, No. 4, 2003.

JM Novi, CS Bradley, G Northington, NN Mahmoud, MA Morgan, LA Arya. Sexual Function in women following rectocele repair with porcine dermis graft versus site-specific rectovaginal fascia repair, International J of Urogynecology, accepted, 2006.

Dolinsky CM, Mahmoud NN, Mick R, Sun W, Whittington RW, Solin LJ, Haller DG, Fry RD, Metz JM. Effect of time interval between surgery and preoperative chemoradiotherapy with 5-fluorouracil (5-FU) or 5-FU/oxaliplatin (5FU/OX) for rectal cancer. Journal of Surgical Oncology, 96:207-12, 2007.

Salinas N, Han D, Carr S, Mahmoud NN. A surprising twist to an old problem: sigmoid volvulus in a 19 year-old. The American Surgeon 2007.

Mahmoud NN, Turpin RS, Saunders WB. Surgical Site Infections, Length of Stay, and Costs Associated with 23,067 Colorectal Procedures. Accepted, Journal of Gastrointestinal Surgery, June 2007.

Paulson EC, Mahmoud NN. Complications of Sigmoid Colon Duplication Cysts: A Review of the Literature. The American Surgeon, accepted, July 2007.

Dolinsky C, Mahmoud NN, Mick Rosemarie et al. Evidence for improved complete response (CR) rate after preoperative chemoradiotherapy with 5-FU/oxaliplatin (5FU/OX) for rectal cancer. Journal of Clinical Oncology, accepted, September 2007.

Abstracts
Carothers AM, Chiao C, Barrett JC, Mahmoud NN, Weyant MJ, Bilinski RT, Churchill MR, Grunberger D, Bertagnolli MM. Caffeic Acid Phenethyl Ester (CAPE) Prevents Tumors in Min/+ Mice and Regulates p53 Function In Vitro. International Society of Cancer Chemoprevention, Strang International Cancer Prevention Conference, November 14, 1998; Annals of the New York Academy of Science, 1999.

Carothers AM, Weyant MJ, Mahmoud NN, Bilinski RT, Bertagnolli MM. Estrogen modulates intestinal tumorigenesis in vitro and in vivo. Proceedings of the American Association of Cancer Research 40:530, 1999.

Mahmoud NN, Madoff RD, Rothenberger DA, Finne CO. TEM Reduces the Incidence of Positive Margins Compared to Transanal Excision for Rectal Tumors. Proceedings of the American Society of Colon and Rectal Surgeons, 2001.

Stein D, Mahmoud NN, Rose D, Anne P, Goldstein S, Isenberg G, Mitchell E, Fry RD. A Longer Time Interval between Completion of Neoadjuvant Chemoradiation and Surgical Resection does not Improve Downstaging of Rectal Carcinoma. Proceedings of the American Society of Colon and Rectal Surgeons, 2002.

Shafi B, Fry RD, Isenberg GA, Goldstein SD, Mahmoud NN. Proband Microsatellite Status May Predict Familial Risk in HNPCC. Collaborative Group of the Americas on Inherited Colorectal Cancer, 2002.

Novi JM, Bradley CS, Northington G, Mahmoud NN, Morgan MA, Arya LA. Sexual Function in women following rectocele repair with porcine dermis graft versus site-specific rectovaginal fascia repair, International Urogynecology Association, 2005.

Dolinsky CM, Mahmoud NN, Mick R, Sun W, Whittington RW, Solin LJ, Haller DG, Fry RD, Metz JM. Effect of time interval between surgery and preoperative chemoradiotherapy with 5-fluorouracil (5-FU) or 5-FU/oxaliplatin (5FU/OX) for rectal cancer. American Society for Therapeutic Radiology and Oncology, 2005.

Dolinsky CM, Mahmoud NN, Mick R, Sun W, Whittington RW, Solin LJ, Haller DG, Giantonio BJ, O’Dwyer PJ, Rombeau JL, Fry RD, Metz JM. Evidence for improved pathologic complete response (PCR) rate after preoperative chemoradiotherapy with 5-FU/oxaliplatin (5FU/OX) for rectal cancer. American Society of Clinical Oncology 2005.

Dolinsky CW, Metz JM, Sun W, Solin L J, Haller D G, O'Dwyer PJ, Rombeau J L, Fry RD, Mahmoud NN. Sphincter Preservation is Improved by Preoperative Oxaliplatin in Locally Advanced Rectal Cancer. American College of Surgeons, submitted, March 2006.

Novi JM, Bradley CS, Northington G, Mahmoud NN, Morgan MA, Arya LA. Sexual function in women following rectocele repair with porcine dermis graft versus site-specific rectovaginal fascia repair. American College of Obstetrics and Gynecology, May 2006.

Mahmoud NN, Turpin RS, Saunders WB. Surgical Site Infections, Length of Stay, and Costs Associated with 23,067 Colorectal Procedures. American Society of Colon and Rectal Surgeons. Poster Presentation, American Society of Colon and Rectal Surgeons, June 2007.

Turpin RS, Mahmoud NN, Guiping Y, Saunders WB. Length of Stay and Costs Associated with Surgical Site Infections in Colon Procedures in a Large US database. International Society for Pharmacoeconomics and Outcomes Research, May 2007.

Editorials, Reviews, Chapters
Mahmoud NN and Bradley B. Peristomal Complications. Intestinal Stomas: Principles, Techniques and Management, 2nd Ed., Revised and Expanded. (eds.) P. Cataldo and J. MacKeigan. Marcel-Dekker, Inc. 2004.

Mahmoud NN and Madoff R. Management of Malignant Tumors of the Anal Canal. Progress in Coloproctology. Ed. J. Beynen and N. Carr. Springer-Verlag. 2004.

Mahmoud NN, Rombeau J, Ross HM, Fry RD. Colon and Rectum. Sabiston Textbook of Surgery, 17th Ed. (ed) C Townsend. W.B. Saunders. 2004.

Mahmoud NN. Preoperative Evaluation of the Colorectal Cancer Patient. Contemporary Surgery. JM Daly (ed). Sept 2004.

Mahmoud NN. Rectal Prolapse. American Society of Colon and Rectal Surgeons Core Subjects. May 2004.

Ross HM, Mahmoud NN, Fry RD. Rectal Cancer. Current Problems in Surgery. Volume 42(2), 2005.

Karmacharya JJ, Mahmoud NN. Surgical Approach to Colorectal Neoplasia and High-risk Conditions. The Clinician’s Guide to Gastrointestinal Oncology. (ed) M. Kochman. Slack, Inc. 2005.

Mahmoud NN, Fry RD. Anal Cancer. Maingot’s Abdominal Operations, 11th ed. M. Zinner, S. Ashley (eds). Appleton & Lange, Stamford CT, 2006.

Mahmoud NN, Fry RD. Radiation Injury to the Small and Large Bowel. Current Surgical Therapy, 9th Ed. JL Cameron (ed), 2006.

Mahmoud NN, Maron DJ, Ross HM, Fry RD. Colon and Rectum. Sabiston Textbook of Surgery, 18th Ed. (ed) C Townsend. W.B. Saunders. 2006.

Fry RD, Mahmoud NN. Segmental Resection for Diverticulitis. Mastery of Surgery. 2007.

Fejka MD, Mahmoud NN. Management of Anal Pain. Surgical Principles for the Practitioner. J Pryor (ed). McGraw-Hill, Inc. 2007.

Kaye A, Gracias VH, Mahmoud NN. Rubber Band Ligation in the Management of Internal Hemorrhoids. US Gastroenterology Review 2007.

Paulson CE, Mahmoud NN. Chapter 11: Colorectal Surgery. Elsevier, In Press, October 2007.

Other Media
2005-present Onco-Link consultant, neoplastic diseases of the colon and rectum. http://www.oncolink.upenn.edu/

 


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