Reconstructive Transplant Surgery - ACRTS

6:15 am

Course Registration and Continental Breakfast

7:00 am

Introductory Remarks - Stefan Schneeberger, MD

7:05 am

Hand Transplantation: From a Personal Perspective - Matt Scott

7:10 am

KEYNOTE LECTURE I:
The Past, Present and Future of Hand Transplantation in the United States
Warren C. Breidenbach, III, MD, FACS

Hand, Face and Abdominal Wall Transplantation - The State of the Art I

Chairs: Warren C. Breidenbach, III, MD, FRCS and Robert L. Walton, MD

7:30 am

Surgical Aspects of Hand Transplantation - Milomir Ninkovic, MD

7:50 am

Surgical Aspects of Face Transplantation - Laurent A. Lantieri, MD

8:10 am

Rehabilitation and Assessment of Function after Hand and Foreman Transplantation - Marina Ninkovic, MD

8:30 am

Functional Outcome after Hand Transplantation - W.P. Andrew Lee, MD

8:50 am

Functional Outcome after Face Transplantation - Bernard Devauchelle, MD, DMD, PhD, FRCS

9:10 am

Abdominal Wall Transplantation: Surgical and Immunological Aspects - Gennaro Selvaggi, MD

9:30 am

Break

Hand, Face and Abdominal Wall Transplantation - The State of the Art II

Chairs: Raimund Margreiter, MD, Jean-Michel Dubernard, MD, PhD

9:45 am

Immunosuppression and Rejection in Human Hand Transplantation - Stefan Schneeberger, MD

10:15 am

Immune Monitoring of the Immunosuppressed Patient - Adriana Zeevi, PhD

10:35 am

Chronic Rejection in CTA: Experimental and Clinical Observations - Vijay S. Gorantla, MD, PhD

10:55 am

Ethics, IRBs, Media and the Public - Arthur L . Caplan, PhD

11:15 am

KEYNOTE LECTURE II:
Strategies for Local Immunosuppression and its Application in CTA
Scott A. Gruber, MD, PhD, MBA, FACS, FCP

11:45 am

Lunch

Strategies for Tolerance Induction I

Chairs: Wayne W. Hancock, MD, PhD and Angus W. Thomson, PhD, DSc

12:45 pm

Depletional Induction Therapy with Campath-1H for Tolerance Induction - Ron Shapiro, MD

1:05 pm

Depletion vs Myeloablation in Organ vs Bone Marrow Transplantation - Suzanne T. Ildstad, MD

1:25 pm

Tolerance Induction Following Kidney and Bone Marrow Transplantation Avoiding Myeloablation - Megan Sykes, MD

1:45 pm

Chimerism and Bone Marrow based Strategies for Tolerance Induction in CTA - Maria Z. Siemionow, MD, PhD, DSc

2:05 pm

All We Need is IDO? - Gerald Brandacher, MD

2:25 pm

Break

Strategies for Tolerance Induction II

Chairs: Abraham Shaked, MD, PhD and Megan Sykes, MD

2:40 pm

Tolerance Induction by Blockade of Co-Stimulatory Pathways - Nader Najafian, MD

3:00 pm

The Balance of Deletion and Regulation in Transplant Tolerance - Xin Xiao Zheng, MD

3:20 pm

Dendritic Cells - The Key to Transplantation Tolerance? - Angus W. Thomson, PhD, DSc

3:40pm

T-regs - Dinosaurs or Mystic Murine Tools for Tolerance Induction? - Robert Lechler MB, ChB, MRCP, PhD, FRCP, FRCPath, FMedSci

4:00 pm

Epigenetic Regulation of Foxp3 and Allograft Tolerance - Wayne W. Hancock, MD, PhD

4:20 pm

The Most Promising Strategies to Induce Tolerance in the Next Decade - Laurence A. Turka, MD

4:40 pm

Break

4:50 pm

Basic Science Free Paper Session - Chairs: Suzanne T. Ildstad, MD & Xin Xiao Zheng, MD

6:00 pm

Adjournment

SATURDAY, July 19, 2008

Establishing a Hand or Face Transplant Program

Chairs: Elisabeth K. Beahm, MD, FACS and Gordon R. Tobin, MD, FACS

7:00 am

Continental Breakfast

7:30 am

Requirements for Establishing a CTA Program: Infrastructure, Personnel, Timeline, Communication and Research - W.P. Andrew Lee, MD

7:50 am

Donor Availability and Collaboration with the OPO - Susan Stuart, RN, MPH

8:10 am

Funding a CTA Program - Vijay S. Gorantla, MD, PhD

8:30 am

Indications and Contraindications for Hand and Face Transplantation - L. Scott Levin, MD, FACS

8:50 am

Role of Composite Tissue Allotransplantation in the United States in the Next Decade - David W. Mathes, MD

9:10 am

The Role of Tissue Engineering in the United States in the Next Decade - Gregory R. D. Evans, MD, FACS

9:30 am

Break

9:50 am

KEYNOTE LECTURE III:
What the Brain Thinks about New Body Parts - Angela Sirigu, MD

10:20 am

Clinical Free Paper Session - Chairs: Steven L. Moran, MD & Joseph E. Losee, MD, FACS, FAAP

11:40 am

Lunch

Prospects and Visions I

Chairs: Gunter Germann, MD, PhD and Julian J. Pribaz, MD

12:40 pm

Novel Strategies for Immunosuppression in Hand and Face Transplantation:
The Pioneering French Experience - Jean-Michel Dubernard, MD, PhD

1:00 pm

Stop Playing, Start Acting: When is the Right Time for Full Face Transplantation? - Peter E. M. Butler MD, FRCSI, FRCS, FRCS

1:20 pm

Reconstructive Transplant Surgery for Burn Victims - Gunter Germann, MD, PhD

1:45 pm

When the Skin is not Enough: Allografts for Skeletal Facial Reconstruction after Maxillofacial Trauma - Paul N. Manson, MD and Edward D. Rodriguez, MD, DDS

2.05 pm

Allotransplantation for Inborn Defects and Deformities: Our Wildest Dreams - Joseph E. Losee, MD, FACS, FAAP

2:25 pm

Reconstructive Transplant Surgery for Indications other than Hand and Face - Joseph M. Serletti, MD, FACS

2:45 pm

Break

Prospects and Visions II

Chairs: Edward A. Athanasian, MD and Steven L. Moran, MD

3:05 pm

How to Optimize Nerve Regeneration after Transplantation: Relevance of Patient Age,
Time Since Amputation and Drug Treatment - Susan Mackinnon, MD

3:25 pm

Arm Transplantation: Options and Limitations - Neil F. Jones, MD

3:45 pm

CTA for Reconstruction under Low Dose Immunosuppression: Risks for Malignancy and Infections - Hugo Bonatti, MD

4:05 pm

Mini Oral Presentation Session I - Chairs: L. Scott Levin, MD, FACS & Maria Z. Siemionow, MD, PhD, DSc

5:25 pm

Closing Remarks - Joseph M. Serletti, MD, FACS

5:30 pm

Course Adjournment