UNIVERSITY OF PENNSYLVANIA HEALTH SYSTEM  
 
 

 

 

Elena Goncharova, Ph.D.
Research Associate

 
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Recent Publications:

Goncharova EA, Goncharov DA, Chisolm A, Spaits MS, Lim PN, Cesarone G, Khavin I, Tliba O, Amrani Y., Panettieri RA, Jr., Krymskaya VP: Interferon beta augments Tuberous Sclerosis Complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human LAM-derived cell proliferation. Mol Pharmacol 73(3):778-788, 2008.
Goncharova EA & Krymskaya VP: Pulmonary Lymphangioleiomyomatosis (LAM): progress and current challenges. J Cell Biochem 103:369-382, 2008.

Goncharova EA, Goncharov DA, Krymskaya VP: Assays for in vitro monitoring of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cell migration. Nature Protocols 1(6):2933-2939, 2006.

Goncharova EA, Lim P, Goncharov DA, Eszterhas A, Panettieri Jr RA, Krymskaya VP: Assays for in vitro monitoring of proliferation of human airway smooth muscle (ASM) and human pulmonary arterial vascular smooth muscle (VSM) cells. Nature Protocols 1(6):2905-2908, 2006.
Goncharova EA, Goncharov DA, Lim PN, Noonan D, Krymskaya VP: Modulation of cell migration and invasiveness by tumor suppressor TSC2 in Lymphangioleiomyomatosis. Am J Respir Cell Mol Biol 34:473-480, 2006.

Goncharova EA, Goncharov DA, Spaits M, Noonan DJ, Talovskaya EV, Eszterhas A, Krymskaya VP: Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis (LAM): Role for tumor suppressor TSC2. Am J Respir Cell Mol Biol 34:561-572, 2006.

Krymskaya VP, Goncharova EA, Ammit AJ, Lim PJ, Goncharov DA, Eszterhas A, Panettieri Jr RA : Src is necessary and sufficient for human airway smooth muscle cell proliferation and migration. FASEB J 19:428-430, 2005.

Goncharova EA, Goncharov DA, Noonan D, Krymskaya VP: TSC2 modulates actin cytoskeleton and cell adhesion through TSC1-binding domain and Rac1 GTPase. J Cell Biol 167:1171-1182, 2004.
Goncharova EA, Billington CK, Irani C, Vorotnikov AV, Tkachuk VA, Penn RB, Krymskaya VP, Panettieri Jr RA: Cyclic AMP-mobilizing agents and glucocorticoids modulate human smooth muscle cell migration. Am J Respir Cell Mol Biol 29:19-27, 2003.

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